CN106619751A - External medicine for treating tinea unguium - Google Patents
External medicine for treating tinea unguium Download PDFInfo
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- CN106619751A CN106619751A CN201510721921.1A CN201510721921A CN106619751A CN 106619751 A CN106619751 A CN 106619751A CN 201510721921 A CN201510721921 A CN 201510721921A CN 106619751 A CN106619751 A CN 106619751A
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- tinea unguium
- onychomycosis
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Abstract
The invention discloses an external medicine for treating tinea unguium. The external medicine comprises, by weight, 1-10 parts of scorpio, 1-5 parts of salicylic acid, 1-8 parts of ketoconazole, 40-70 parts of propolis, 15-40 parts of herba speranskiae tuberculatae, 1-5 parts of laurocapram and 15-30 parts of sesame oil. The external medicine for treating the tinea unguium has the advantages that the external medicine is high in adhesion and cure rate, durable in efficacy and free of irritation and can be permeated into stratum corneum to kill fungi, and accordingly good treatment effects can be realized.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of externally applied drug for treating onychomycosis.
Background technology
Onychomycosis, the traditional Chinese medical science is referred to as curled paralysis, and tinea, doctor trained in Western medicine claims onychomycosis, refers to that dermatophytes invades disease caused under deck or first.Onychomycosis is by the fungus-caused first infection such as dermatophytes, saccharomycete and non-dermatophytes.Common two type of first fungi：1. the white first of fungoid（Shallow white onychomycosis）This kind of disease damage is confined to that first face is a piece of or its is sophisticated；2. nosomycosis under first, divides distal side bit-type, near-end first mo(u)ld bottom half and superficial white type, this kind of pathology to infect under deck then from the beginning of the both sides or distal end of first again.
Onychomycosis is a kind of refractory skin.At present, multiplex ointment, liquid medicine class agent, and endo-medicine for example griseofulvin, terbinafine HCl piece, Itraconazole,SporanoxDeng treatment, poor with rear effect, cure rate is low, it is difficult to effect a radical cure, it is easy to recur.Trace it to its cause, endo-medicine large side effects, it is impossible to adhere to taking for a long time；External used medicine is in addition to drug factors, it is because that first matter is a kind of fine and close connective tissue, drug penetration in above-mentioned preparation is weak, it is difficult to mycelia and the spore of fungi are killed or suppressed into cuticula, and above-mentioned preparation and biological tissue's adhesion are weak, it is easy to fall off, uncomplicated laundering is sloughed, and medicine time of staying at first is short, without the living environment for effectively changing pathogenic bacteria, killing direct to fungi is difficult to, is easily sprouted again.
The content of the invention
In view of the problem that prior art is present, the present invention provides that a kind of antifungal effect of killing is good, and adhesive force is strong, and lasting medicine is nonirritant, medicine can be made to enter cuticula and kill fungi, and therapeutic effect is good, the externally applied drug of the high treatment onychomycosis of cure rate.
The task of the present invention is completed as follows, and it is made up of the component of the material medicine proportioning of following weight：Scorpio 1--10, salicylic acid 1--5, ketoconazole 1--8, propolis 40--70, lopseed 15--40, azone 1--5, sesame oil 15--30.
Currently preferred bulk drug composition by weight is respectively：Scorpio 7, salicylic acid 3, ketoconazole 6, propolis 65, lopseed 28, azone 1.5, sesame oil 20.
The further preferred bulk drug composition by weight of the present invention is respectively：Scorpio 10, salicylic acid 5, ketoconazole 4, propolis 50, lopseed 20, azone 2, sesame oil 15.
Preparation method：
1st, lopseed is added water to cook into method according to conventional Chinese medicine, is decocted twice, 30 minutes for the first time, second 20 minutes, merging filtrate, concentration dry, pulverize, and cross 200 mesh sieves, standby.
2nd, by scorpio, by several times being put into sesame oil fries withered, and oil strain waste is standby.
3rd, it is homogeneous after 2, after being cooled to 50 °C, sequentially add salicylic acid, ketoconazole, azone, finally by 1, add, stir, keep 45 °C it is standby.
4th, propolis is put into 3-4 hours in 70 °C of insulating boxs, during into dilute cream shape, 3, addition is stirred evenly, be cooled to compared with plaster, be this product.
Using method：
Appropriate externally applied drug of the present invention is taken, disease first size, 2mm thickness pieces is pinched into, affected part is affixed on and is wrapped up, changed within 4 days one, first with blade the softening part topical application of drug again of nail matrix, 4 courses for the treatment of are removed during each dressing.
Effect of each material medicine and effect in the present invention：
Scorpio：It is pungent, put down；It is poisonous.Return liver warp.Indication：Ceases wind antispastic, dispersing pathogen accumulation is removed obstruction in channels to relieve pain.For child convulsion, tic spasm, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.Scorpion venom to nervous system, digestive system, cardio-cerebrovascular, cancer, skin disease, etc. various diseases, and the various viruses very harmful to the mankind have prevention and inhibitory action.
Salicylic acid：Salicylic acid is usually used in treating various chronic dermatosis such as acne in dept. of dermatology（Whelk）, tinea etc..Salicylic acid can dispel cutin, sterilization, anti-inflammatory.
Ketoconazole：For the candidiasis for the treatment of 1. of following systemic fungal infection, chronic mucocutaneous beads disease, oral cavity monilial infection, urinary tract monilial infection, local treatment invalid chronic, recurrent vaginal candidiasis.2. blastomycetic dermatitidis.3. coccidioidomycosis.4. histoplasmosis.5. chromoblastomycosis.6. paracoccidioidomycosis.By dermatophyte and saccharomycetic dermatomycosis, tinea versicolor and tinea capitis.
Propolis：Mild-natured, bitter, pungent, micro-sweet have moisturizing myogenic, and effect of anti-inflammatory analgetic can treat the illnesss such as gastric ulcer, canker sore, burn and scald, skin Tearing Pain, radiation proof.With antibacterial, anti-inflammatory, it is antipruritic, anti-oxidant, strengthen immune, hypoglycemic, reducing blood lipid, the several functions such as antitumor, 1967, the Lin Dengfoersai in the U.S.（Lindenfelser）Research have shown that propolis has inhibitory action to 25 kinds of bacteriums.
Lopseed：It is sweet, it is nontoxic.Indication:Wind-dispelling, dehumidifying, relaxing muscles and tendons, promoting blood circulation, pain relieving.Control arthralgia due to wind-dampness, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, sore tinea pyogenic infections.《Book on Chinese herbal medicine is just》：It is " deep sensible.”
Azone：The oily liquids of colourless to the yellowish clarification of this product;Odorless, it is almost tasteless.As bleeding agent, for all kinds of creams and hair care product in cosmetics;The penetrating agent smear as external used medicine, massaged;For agricultural chemicals, as plant growth regulator vapor and sterilization, the penetrating agent of insecticide are promoted;
Sesame oil：Nature and flavor are sweet, cool, the effect of with relaxing bowel, solving taking poison and growing muscle due.According to《Compendium of Materia Medica》Upper record:" have moisturize, detoxify, pain relieving, the work(of detumescence.
The ingenious compatibility of the present invention, anti-inflammation and sterilization, dispersing pathogen accumulation is deep sensible, cutin-softening, suppresses virus, treatment dermatophyte and saccharomycetic dermatomycosis, and Each performs its own functions, brings out the best in each other, and adds the strong osmotic effect of azone, and the efficacy of a drug is gone directly focus.
Using the present invention external plaster treatment onychomycosis 115, cure 112, effective 3, efficient 100%, cure rate 97.3%.
Specific embodiment
Embodiment
Take according to the further preferred material medicine of the present invention：Scorpio 10, salicylic acid 5, ketoconazole 4, propolis 50, lopseed 20, azone 2, sesame oil 15.
Preparation method：
1、
Lopseed is added water to cook into method according to conventional Chinese medicine, is decocted twice, 30 minutes for the first time, second 20 minutes, merging filtrate, concentration dry, pulverize, and cross 200 mesh sieves, standby.
2nd, by scorpio, by several times being put into sesame oil fries withered, and oil strain waste is standby.
3rd, it is homogeneous after 2, after being cooled to 50 °C, sequentially add salicylic acid, ketoconazole, azone, be eventually adding 1, stir, keep 45 °C it is standby.
4th, propolis is put into 3-4 hours in 70 °C of insulating boxs, during into dilute cream shape, 3, addition is stirred evenly, be cooled to compared with plaster, be this product.
Using method：
Appropriate externally applied drug of the present invention is taken, disease first size, 2mm thickness pieces is pinched into, affected part is affixed on and is wrapped up, changed within 4 days one, first with blade the softening part topical application of drug again of nail matrix, 4 courses for the treatment of are removed during each dressing.
Hereinafter several cases are enumerated in conjunction with the clinical practice record of the medicine obtained by embodiment, the effect of the present invention is illustrated：
Case one
On June 23rd, 2011, king X X, female, 49 years old, peasant, bipod big toe suffered from fungoid Bai Jiasan, and once the paste of used treatment onychomycosis, tincture effect did not showed, and using the course for the treatment of of embodiment medicine one and half new first is grown.Visit after 1 year and do not recur.
Case two
2013, September 10 days, Liu X X, man, 52 years old, workman suffered from onychomycosis for many years, and nail grey is thickened, deformation, and once the paste of used treatment onychomycosis, tincture and balsamine wrapping effect did not showed, and using embodiment medicine, the course for the treatment of of medication two grows new first.Visit after 1 year and do not recur.
Case three
On August 19th, 2014, Zhao X, female, 53 years old, retired worker, two hand thumbs and forefinger suffered from onychomycosis 5 years, and nail grey is thickened, and deformation affects attractive in appearance.Once the paste of used treatment onychomycosis, tincture effect did not showed, take again afterwards Itraconazole,Sporanox, effect still, after make big drug withdrawal and recur because secondary.New first is grown using the course for the treatment of of embodiment medicine two.Visit after a year and a half and do not recur.
Claims (1)
1. a kind of externally applied drug for treating onychomycosis, it is characterised in that it is made up of the component of the material medicine proportioning of following weight：Scorpio 1--10, salicylic acid 1--5, ketoconazole 1--8, propolis 40--70, lopseed 15--40, azone 1--5, sesame oil 15--30.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721921.1A CN106619751A (en) | 2015-10-31 | 2015-10-31 | External medicine for treating tinea unguium |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721921.1A CN106619751A (en) | 2015-10-31 | 2015-10-31 | External medicine for treating tinea unguium |
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| Publication Number | Publication Date |
|---|---|
| CN106619751A true CN106619751A (en) | 2017-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510721921.1A Pending CN106619751A (en) | 2015-10-31 | 2015-10-31 | External medicine for treating tinea unguium |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109303815A (en) * | 2018-12-17 | 2019-02-05 | 江西博汇生物科技有限公司 | A kind of plant extract formula applied to onychomycosis and the ringworm of the foot |
-
2015
- 2015-10-31 CN CN201510721921.1A patent/CN106619751A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109303815A (en) * | 2018-12-17 | 2019-02-05 | 江西博汇生物科技有限公司 | A kind of plant extract formula applied to onychomycosis and the ringworm of the foot |
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170510 |
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| WD01 | Invention patent application deemed withdrawn after publication |