CN106619746A - Ganoderma spore powder granules - Google Patents
Ganoderma spore powder granules Download PDFInfo
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- CN106619746A CN106619746A CN201610912388.1A CN201610912388A CN106619746A CN 106619746 A CN106619746 A CN 106619746A CN 201610912388 A CN201610912388 A CN 201610912388A CN 106619746 A CN106619746 A CN 106619746A
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- Prior art keywords
- powder particles
- reishi sporule
- ganoderma
- sporule powder
- granules
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- 239000000843 powder Substances 0.000 title claims abstract description 94
- 241000222336 Ganoderma Species 0.000 title claims abstract description 33
- 239000008187 granular material Substances 0.000 title abstract description 8
- 239000002245 particle Substances 0.000 claims abstract description 54
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 52
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 52
- 150000003648 triterpenes Chemical class 0.000 claims abstract description 11
- 239000002253 acid Substances 0.000 claims abstract description 9
- 150000002978 peroxides Chemical class 0.000 claims abstract description 8
- 239000000126 substance Substances 0.000 claims abstract description 8
- 238000001291 vacuum drying Methods 0.000 claims description 29
- 239000002994 raw material Substances 0.000 claims description 25
- 238000001035 drying Methods 0.000 claims description 22
- 238000002156 mixing Methods 0.000 claims description 16
- 235000020985 whole grains Nutrition 0.000 claims description 11
- -1 washing Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 7
- 230000008030 elimination Effects 0.000 claims description 7
- 238000003379 elimination reaction Methods 0.000 claims description 7
- 239000004744 fabric Substances 0.000 claims description 7
- 239000012467 final product Substances 0.000 claims description 7
- 239000012535 impurity Substances 0.000 claims description 7
- 238000010348 incorporation Methods 0.000 claims description 7
- 239000008213 purified water Substances 0.000 claims description 7
- 238000005406 washing Methods 0.000 claims description 7
- 238000005550 wet granulation Methods 0.000 claims description 7
- 238000005469 granulation Methods 0.000 claims description 4
- 230000003179 granulation Effects 0.000 claims description 4
- 244000000231 Sesamum indicum Species 0.000 claims 1
- 235000003434 Sesamum indicum Nutrition 0.000 claims 1
- 238000002604 ultrasonography Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract description 7
- 150000004676 glycans Chemical class 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 229920001282 polysaccharide Polymers 0.000 abstract description 4
- 239000005017 polysaccharide Substances 0.000 abstract description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract description 2
- 229910052782 aluminium Inorganic materials 0.000 abstract description 2
- 230000000975 bioactive effect Effects 0.000 abstract description 2
- 238000005265 energy consumption Methods 0.000 abstract description 2
- 239000002904 solvent Substances 0.000 abstract description 2
- 230000007547 defect Effects 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 12
- 238000000034 method Methods 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 235000013339 cereals Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000002932 luster Substances 0.000 description 6
- 238000004737 colorimetric analysis Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 3
- 235000011089 carbon dioxide Nutrition 0.000 description 3
- 235000019441 ethanol Nutrition 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 1
- 240000006891 Artemisia vulgaris Species 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 description 1
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000290333 Vanilla fragrans Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000011953 bioanalysis Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011868 grain product Nutrition 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 230000029052 metamorphosis Effects 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229940100243 oleanolic acid Drugs 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses ganoderma spore powder granules, having acid value of (0.1-0.2) KOH mg/g, and peroxide value index of (0.01-0.03) g/100 g, with the content of indicative functional component ganoderma total triterpenes being (3-5) g/100 g, and the content of ganoderma lucidum polysaccharides being (0.5-2.0) g/100 g. Compared with the prior art, the granules have no need for the addition of any auxiliaries during preparation; the prepared granules never loosen and have uniform particle size and good mobility; the defect that traditional ganoderma spore powder is poor in mobility, sticky to aluminum film and inconvenient to take is overcome; the obtained granules can well retain the original taste and color of ganoderma powder; the granules of the invention can well retain bioactive substances in ganoderma powder so that the granules are insusceptible to temperature, chemical solvents and other factors; the production cycle is shortened, labor intensity is reduced, energy consumption is lowered, and production efficiency is improved.
Description
Technical field
The invention belongs to lucidum spore powder Related product field, and in particular to a kind of Reishi sporule powder particles.
Background technology
Lucidum spore powder is that after ganoderma lucidum fruitbody is reached maturity, collection is formed by the spore ejected in tube.It collects
The elite of glossy ganoderma, nutritive value is far above ganoderma lucidum mycelium and fructification.Contain several amino acids, inorganic battalion in lucidum spore powder
Foster element, triterpene compound, alkaloid, phytosterin compound, ucleosides, macromolecule polysaccharide and other many physiologically active things
Matter.Modern pharmacology proves that lucidum spore powder has and adjusts the effects such as immunity, activating macrophage, regulation and control glucocorticoid.Due to
Reishi sporule has double-deck tough and tensile chitin, peptide glycan outer wall, and human body cannot clear up glossy ganoderma cell wall.Research has shown that, glossy ganoderma
Metamorphosis is obvious before and after lucidium spore powder wall breaking；After broken wall in conidia powder extract reduced sugar and peptide content obviously higher than broken wall
Before.Zoopery confirms, under same dose, the effect of immune function of mice is noticeably greater than before broken wall after lucidium spore powder wall breaking.Adopt
The biological effect of lucidum spore powder can be given full play to effective method broken wall.Ganoderma spove powder is by lucidum spore powder
Come, be the enrichment or concentration of all bioactive ingredients in a kind of lucidum spore powder, it eliminates human body can not digest decomposition
Reishi sporule cell membrane so that the bioactivator in Reishi sporule is easy to the absorption of human body, is utilized.
The technology for broken wall of lucidum spore powder is broadly divided into 5 classes:Bioanalysis, chemical method, Physical, Mechanical Method, synthesis.
Conidia powder poor fluidity after broken wall, it is greasy, meet that water is agglomerating sticks at molten device or packing material surface, have a strong impact on its consumption.
Typically ganoderma spove powder is made into particle, to improve its physical behavior.Generally it is dried conidia powder with heated-air circulation oven
Wet grain, and most directly affecting that the wet grain of high temperature drying conidia powder is brought is exactly feature substance bioactivity in lucidum spore powder
Decline.
The content of the invention
Goal of the invention：In order to solve above-mentioned technical problem, the present invention provides a kind of Reishi sporule powder particles.
Technical scheme：In order to realize foregoing invention purpose, the invention discloses a kind of Reishi sporule powder particles, the glossy ganoderma
In spore powder particles, its acid value is (0.1-0.2) KOHmg/g, and its peroxide value index is respectively (0.01-0.03) g/100g,
Significant functional component Ganoderma total triterpenes kind compound content is (3-5) g/100g, and ganoderma polyoses content is (0.5-2.0) g/
100g。
Preferably, in the Reishi sporule powder particles, its acid value is (0.14-0.16) KOHmg/g, its peroxide value refers to
Mark is respectively (0.018-0.028) g/100g, and significant functional component Ganoderma total triterpenes kind compound content is (4.05-4.30)
G/100g, ganoderma polyoses content is (1.3-1.8) g/100g.
As another kind preferably, in the Reishi sporule powder particles, the cell membrane of Reishi sporule is damaged state.
As another kind preferably, the Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size.
As another kind preferably, described Reishi sporule powder particles are mainly made up of following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Vacuum and vacuum drying time are set, moisture≤6% after vacuum drying is made；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 3-5h is placed；Then exist
Under the conditions of 40～70 DEG C, ultrasonic wave mixing broken wall is carried out；
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：(0.3-0.4) ratio is carried out
Mixing granulation；
(5) pneumatic conveying drying：EAT is set：50-60 DEG C, leaving air temp：35-40 DEG C, flow velocity：4500-5000m3/ s,
Carry out pneumatic conveying drying, drying time 3.5-4 hour, then whole grain, obtains final product.
As another kind preferably, vacuum described in step (2) is 0.7-1.0MPa, and vacuum drying time is 4-8h.
As another kind preferably, the supersonic frequency of ultrasonic wave described in step (3) is 18-22 KHzs, and incorporation time is 4
～12min, mixing rotating speed is 20～50rpm.
Preferably pelletize described in step (4) and pelletized using rotating pelletizer as another kind of, granulator rotating speed：50-
60rpm, screen cloth：11-13 mesh.
As another kind preferably, whole grain carries out whole grain using 15-17 eye mesh screens described in step (5).
The present invention is using the brittle broken wall of freezing, it is only necessary under the conditions of -18 DEG C, places embrittlement 3-5h, then carries out ultrasonic wave and breaks
Wall, you can reach more than 99% sporoderm-broken rate, condition requires low, process is simple, without the need for adding any auxiliary material, and can effectively protect
The active ingredient in raw material is stayed, sporoderm-broken rate is high.Have in prior art and 5-120 minutes are processed using superfreeze in liquid nitrogen, so
After be stored at room temperature, and repeated multiple times wall-breaking method, the method high cost, complex operation, condition has high demands, and broken wall is imitated
Fruit is not good；Also technology is placed in raw material in the mixture of dry ice and absolute ethyl alcohol, and using ultrasonic wave mechanical crushing broken wall is carried out,
Although the technology is also adopted by supersonic wave wall breaking, its broken wall is still needed at low ambient temperatures, and also need to add dry ice and
Absolute ethyl alcohol, in addition to increasing cost, absolute ethyl alcohol can destroy wherein active ingredient, or even cause residual.
Gained lucidum spore powder grain products of the invention without any auxiliary material, using cryogenic freezing broken wall, 38 DEG C of low temperature
Air-flow dynamic dry technology prepares Reishi sporule (broken wall) powder particles.The technical scheme has abandoned traditional 90～110 DEG C high temperature
Laminate is heated, and various bioactivators in ganoderma spove powder is not destroyed by high temperature heat source, and avoids traditional handicraft high
The time-consuming power consumption for putting raw material is manually turned in warm dry run.The method have also been changed greasy, the viscous thing of ganoderma spove powder
Reason characteristic, the drawbacks of could being pelletized with chemical adhesives such as ethanol.
Additionally, low-temperature airflow dynamic drying process and can effectively intercept the Reishi sporule escaped because of air-flow fluidized drying
Dry particl so as to which number of dropouts is less than 1%.The ganoderma spove powder particle (chewing granulate agent) prepared with the technology, each
There is the breakthrough of matter on item functional parameter.Compared with ganoderma spove powder product is dried with heated-air circulation oven, this product
Moist wood drying time be 3.5～4 hours.The ganoderma spove powder particle prepared with the technique, its acid value, peroxide value refer to
Mark is respectively (0.1-0.2) KOHmg/g, (0.01-0.03) g/100g, and significant functional component Ganoderma total triterpenes class compound contains
Amount up to (3-5) g/100g g (and the ganoderma spove powder particle prepared with traditional hot air circulation drying means, when it is dried
Between be 18～22 hours, acid value, peroxide value index are respectively 8.60KOHmg/g or so, 9.7g/100g or so, triterpenes
Compound content is only 1.6g/100g or so).The mouthfeel of this product, freshness are all greatly improved, without tradition Reishi sporule
The wormwood artemisia taste of powder, but a kind of pleasant sesame oil and lucid ganoderma spore powder polysaccharide alcohol fragrance.When this product is taken also easily, biography is changed
System lucidum spore powder absorption aluminium foil bag phenomenon.
Technique effect：Relative to prior art, the technology of the present invention has the advantage that：
1st, be not required to add any auxiliary material in particulate production of the present invention, made by particle is loose, even particle size,
Good fluidity, the traditional lucidum spore powder poor fluidity of change, the viscous shortcoming be stained with aluminium film, take inconvenience；
2nd, gained particle remains well original mouthfeel and color and luster of lucidum spore powder；
3rd, particle of the present invention remains well the bioactivator in lucidum spore powder so as to from temperature, chemistry
The impact of the factors such as solvent；Simultaneously the production cycle is shortened, alleviate labour intensity, reduce energy consumption, improve production efficiency.
Specific embodiment
Embodiment 1
The preparation technology of Reishi sporule powder particles, comprises the following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Setting vacuum be 0.9MPa, vacuum drying time is 6h, make moisture after vacuum drying≤
6%；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 3h is placed；Then 50
Under the conditions of DEG C, ultrasonic wave mixing broken wall is carried out；The supersonic frequency of the ultrasonic wave is 20 KHzs, and incorporation time is 5min, is mixed
Conjunction rotating speed is 40rpm.
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：0.3 ratio carries out mixing system
Grain；Pelletized using rotating pelletizer, granulator rotating speed：55rpm, screen cloth：12 mesh.
(5) pneumatic conveying drying：EAT is set：55 DEG C, leaving air temp：38 DEG C, flow velocity：4800m3/ s, carries out air-flow and does
Dry, 3.5 hours drying times, then 16 eye mesh screen whole grain, obtains final product.
Gained Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size, good fluidity, and remains spirit
Original mouthfeel of Ganoderma lucidum spore powder and color and luster.
Embodiment 2
The preparation technology of Reishi sporule powder particles, comprises the following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Setting vacuum be 0.9MPa, vacuum drying time is 6h, make moisture after vacuum drying≤
6%；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 5h is placed；Then 60
Under the conditions of DEG C, ultrasonic wave mixing broken wall is carried out；The supersonic frequency of the ultrasonic wave is 20 KHzs, and incorporation time is 10min, is mixed
Conjunction rotating speed is 30rpm.
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：0.4 ratio carries out mixing system
Grain；Pelletized using rotating pelletizer, granulator rotating speed：55rpm, screen cloth：12 mesh.
(5) pneumatic conveying drying：EAT is set：55 DEG C, leaving air temp：38 DEG C, flow velocity：4800m3/ s, carries out air-flow and does
Dry, 4 hours drying times, then 16 eye mesh screen whole grain, obtains final product.
Gained Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size, good fluidity, and remains spirit
Original mouthfeel of Ganoderma lucidum spore powder and color and luster.
Embodiment 3
The preparation technology of Reishi sporule powder particles, comprises the following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Setting vacuum be 0.9MPa, vacuum drying time is 6h, make moisture after vacuum drying≤
6%；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 4h is placed；Then 55
Under the conditions of DEG C, ultrasonic wave mixing broken wall is carried out；The supersonic frequency of the ultrasonic wave is 20 KHzs, and incorporation time is 8min, is mixed
Conjunction rotating speed is 35rpm.
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：0.35 ratio is mixed
Granulation；Pelletized using rotating pelletizer, granulator rotating speed：55rpm, screen cloth：12 mesh.
(5) pneumatic conveying drying：EAT is set：55 DEG C, leaving air temp：38 DEG C, flow velocity：4800m3/ s, carries out air-flow and does
Dry, 3.8 hours drying times, then 16 eye mesh screen whole grain, obtains final product.
Gained Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size, good fluidity, and remains spirit
Original mouthfeel of Ganoderma lucidum spore powder and color and luster.
Embodiment 4
The preparation technology of Reishi sporule powder particles, comprises the following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Vacuum and vacuum drying time are set, and vacuum is 0.7MPa, and vacuum drying time is 4h,
Make moisture≤6% after vacuum drying；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 5h is placed；Then 40
Under the conditions of DEG C, ultrasonic wave mixing broken wall is carried out, the supersonic frequency of ultrasonic wave is 18 KHzs, and incorporation time is 4min, and mixing turns
Speed is 50rpm；
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：0.3 ratio carries out mixing system
Grain, is pelletized using rotating pelletizer, granulator rotating speed：50rpm, screen cloth：11 mesh；
(5) pneumatic conveying drying：EAT is set：50 DEG C, leaving air temp：35 DEG C, flow velocity：4500m3/ s, carries out air-flow and does
It is dry, 3.5 hours drying times, then whole grain is carried out using 15 eye mesh screens, obtain final product.
Gained Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size, good fluidity, and remains spirit
Original mouthfeel of Ganoderma lucidum spore powder and color and luster.
Embodiment 5
The preparation technology of Reishi sporule powder particles, comprises the following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Vacuum and vacuum drying time are set, and vacuum is 1.0MPa, and vacuum drying time is 8h,
Make moisture≤6% after vacuum drying；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 3h is placed；Then 70
Under the conditions of DEG C, ultrasonic wave mixing broken wall is carried out, the supersonic frequency of ultrasonic wave is 22 KHzs, and incorporation time is 12min, and mixing turns
Speed is 20rpm；
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：0.4 ratio carries out mixing system
Grain, is pelletized using rotating pelletizer, granulator rotating speed：60rpm, screen cloth：13 mesh；
(5) pneumatic conveying drying：EAT is set：60 DEG C, leaving air temp：40 DEG C, flow velocity：5000m3/ s, carries out air-flow and does
It is dry, 4 hours drying times, then whole grain is carried out using 17 eye mesh screens, obtain final product.
Gained Reishi sporule powder particles oil-free is greasy, sticking phenomenon, even particle size, good fluidity, and remains spirit
Original mouthfeel of Ganoderma lucidum spore powder and color and luster.
The measure of active material in experimental example present invention gained Reishi sporule powder particles
Acid value is determined using GB/T 5009.37；
Peroxide value index is determined using GB/T 5009.37；
Using colorimetric method for determining Ganoderma total triterpenes kind compound content, (triterpene substance in glossy ganoderma is under perchloric acid effect
Coloring matter is generated with vanilla aldehyde reaction.Under 545nm wavelength, its absorbance size is directly proportional to triterpenes content.With
Oleanolic acid is reference substance, with the content of colorimetric method for determining triterpene substance)；
Using colorimetric method for determining ganoderma polyoses content, (polysaccharide is hydrolyzed into monose, and rapid dehydration shape under concentrated sulfuric acid effect
Generate alditol derivative, the effect of the derivative and phenol generates orange-yellow compound, product color within the specific limits with water
The contents of monosaccharides linear correlation that solution is formed, with colorimetric method for determining product absorbance, with glucose as a standard, can calculate sample
Soluble ganoderma polyoses content in product).
Measurement result such as table 1 below.
1 group is compareed using the method for the embodiment of the present invention 3, be the difference is that only：Using traditional hot air circulation drying means
The Reishi sporule powder particles of preparation.
2 groups are compareed using the method for the embodiment of the present invention 3, be the difference is that only：Dry ice and anhydrous second are placed in using raw material
In the mixture of alcohol, mechanical crushing broken wall, prepared Reishi sporule powder particles are carried out using ultrasonic wave.
The each index determining result of the Reishi sporule powder particles of table 1
Can be obtained by the result of upper table 1, compare two control groups, present invention gained Reishi sporule powder particles, its acid value and mistake
Oxidation number index is greatly reduced；And significant functional component Ganoderma total triterpenes kind compound content is significantly improved, show this
Bright gained lucidum spore powder particulates' properties are projected, and advantage is notable.
Additionally, 1 group of gained ganoderma lucidium spore powder wall breaking rate of control can also reach more than 99%, but compare 2 groups of broken wall
Rate is decreased obviously, and shows that the inventive method gained sporoderm-broken rate is greatly improved, and advantage is notable.
Claims (9)
1. a kind of Reishi sporule powder particles, it is characterised in that the Reishi sporule powder particles, its acid value is (0.1-0.2)
KOHmg/g, its peroxide value index is respectively (0.01-0.03) g/100g, significant functional component Ganoderma total triterpenes class chemical combination
Thing content is (3-5) g/100g, and ganoderma polyoses content is (0.5-2.0) g/100g.
2. Reishi sporule powder particles according to claim 1, it is characterised in that the Reishi sporule powder particles, its acid value
For (0.14-0.16) KOHmg/g, its peroxide value index is respectively (0.018-0.028) g/100g, significant functional component spirit
Sesame total triterpene kind compound content is (4.05-4.30) g/100g, and ganoderma polyoses content is (1.3-1.8) g/100g.
3. Reishi sporule powder particles according to claim 1, it is characterised in that in the Reishi sporule powder particles, glossy ganoderma
Archespore wall is damaged state.
4. Reishi sporule powder particles according to claim 1, it is characterised in that the Reishi sporule powder particles oil-free is greasy,
Sticking phenomenon, even particle size.
5. Reishi sporule powder particles according to claim 1, it is characterised in that it is mainly made up of following steps：
(1) raw material prepare：Take lucidum spore powder raw material, washing, impurity elimination；
(2) it is vacuum dried：Vacuum and vacuum drying time are set, moisture≤6% after vacuum drying is made；
(3) brittle broken wall is freezed：By the raw material after vacuum drying under the conditions of -18 DEG C, embrittlement 3-5h is placed；Then 40～
Under the conditions of 70 DEG C, ultrasonic wave mixing broken wall is carried out；
(4) wet granulation：By the lucidum spore powder after broken wall and purified water with mass ratio 1：(0.3-0.4) ratio is mixed
Granulation；
(5) pneumatic conveying drying：EAT is set：50-60 DEG C, leaving air temp：35-40 DEG C, flow velocity：4500-5000m3/ s, is carried out
Pneumatic conveying drying, drying time 3.5-4 hour, then whole grain, obtains final product.
6. Reishi sporule powder particles according to claim 5, it is characterised in that vacuum described in step (2) is 0.7-
1.0MPa, vacuum drying time is 4-8h.
7. Reishi sporule powder particles according to claim 5, it is characterised in that the ultrasound of ultrasonic wave described in step (3)
Frequency is 18-22 KHzs, and incorporation time is 4～12min, and mixing rotating speed is 20～50rpm.
8. Reishi sporule powder particles according to claim 5, it is characterised in that granulation is using rotation described in step (4)
Granulator is pelletized, granulator rotating speed：50-60rpm, screen cloth：11-13 mesh.
9. Reishi sporule powder particles according to claim 5, it is characterised in that whole grain adopts 15-17 described in step (5)
Eye mesh screen carries out whole grain.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108142922A (en) * | 2018-02-01 | 2018-06-12 | 河北工程大学 | Reishi sporule powder capsule and preparation method thereof |
| CN110419717A (en) * | 2019-07-18 | 2019-11-08 | 中华全国供销合作总社济南果品研究院 | A kind of preparation method avoiding viscous wall and the ganoderma spove powder for delaying oxidation |
| CN110506937A (en) * | 2019-09-26 | 2019-11-29 | 张北壮 | A kind of simple granulation process of glossy ganoderma spore powder with crushed sporoderm |
| CN111743874A (en) * | 2020-07-22 | 2020-10-09 | 芜湖御草医药有限公司 | Method for preparing ganoderma lucidum spore powder capsule |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973616A (en) * | 2012-12-25 | 2013-03-20 | 江南大学 | High-bioactivity ganoderma spore oil and supercritical preparation method thereof |
| CN104073344A (en) * | 2014-07-16 | 2014-10-01 | 江苏斯威森生物医药工程研究中心有限公司 | Extracting method for ganoderma lucidum spore oil |
| CN104388308A (en) * | 2014-10-11 | 2015-03-04 | 广州英佩尔电子科技有限公司 | Comprehensive micro-molecule wall breaking machine used for fresh food materials and fresh medicinal materials |
| CN104857030A (en) * | 2015-04-30 | 2015-08-26 | 黄宇明 | Wall breaking method for ganoderma lucidum spore powder and product obtained with same |
| CN104940248A (en) * | 2015-07-15 | 2015-09-30 | 杭州德标科技有限公司 | Cell wall breaking method of ganoderma lucidum spore powder |
| CN105820873A (en) * | 2016-04-28 | 2016-08-03 | 合肥云峰信息科技有限公司 | Extraction method of ganoderma lucidum spore oil |
-
2016
- 2016-10-19 CN CN201610912388.1A patent/CN106619746B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973616A (en) * | 2012-12-25 | 2013-03-20 | 江南大学 | High-bioactivity ganoderma spore oil and supercritical preparation method thereof |
| CN104073344A (en) * | 2014-07-16 | 2014-10-01 | 江苏斯威森生物医药工程研究中心有限公司 | Extracting method for ganoderma lucidum spore oil |
| CN104388308A (en) * | 2014-10-11 | 2015-03-04 | 广州英佩尔电子科技有限公司 | Comprehensive micro-molecule wall breaking machine used for fresh food materials and fresh medicinal materials |
| CN104857030A (en) * | 2015-04-30 | 2015-08-26 | 黄宇明 | Wall breaking method for ganoderma lucidum spore powder and product obtained with same |
| CN104940248A (en) * | 2015-07-15 | 2015-09-30 | 杭州德标科技有限公司 | Cell wall breaking method of ganoderma lucidum spore powder |
| CN105820873A (en) * | 2016-04-28 | 2016-08-03 | 合肥云峰信息科技有限公司 | Extraction method of ganoderma lucidum spore oil |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108142922A (en) * | 2018-02-01 | 2018-06-12 | 河北工程大学 | Reishi sporule powder capsule and preparation method thereof |
| CN110419717A (en) * | 2019-07-18 | 2019-11-08 | 中华全国供销合作总社济南果品研究院 | A kind of preparation method avoiding viscous wall and the ganoderma spove powder for delaying oxidation |
| CN110506937A (en) * | 2019-09-26 | 2019-11-29 | 张北壮 | A kind of simple granulation process of glossy ganoderma spore powder with crushed sporoderm |
| CN111743874A (en) * | 2020-07-22 | 2020-10-09 | 芜湖御草医药有限公司 | Method for preparing ganoderma lucidum spore powder capsule |
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