CN106617069A - Blueberry and rhodiola rosea composite oral liquid and preparation method thereof - Google Patents

Blueberry and rhodiola rosea composite oral liquid and preparation method thereof Download PDF

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Publication number
CN106617069A
CN106617069A CN201710034029.5A CN201710034029A CN106617069A CN 106617069 A CN106617069 A CN 106617069A CN 201710034029 A CN201710034029 A CN 201710034029A CN 106617069 A CN106617069 A CN 106617069A
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China
Prior art keywords
blueberry
oral liquid
rhodiola root
concentrated
rhodiola rosea
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CN201710034029.5A
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Chinese (zh)
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毛迪锐
洪海成
常凯
孙广仁
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Beihua University
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Beihua University
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Priority to CN201710034029.5A priority Critical patent/CN106617069A/en
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Abstract

The invention discloses a blueberry and rhodiola rosea composite oral liquid and a preparation method thereof. The blueberry and rhodiola rosea composite oral liquid comprises the following components in percentage by weight: 30 to 80 percent of blueberries, 10 to 15 percent of rhodiola rosea, 6 to 10 percent of white granulated sugar, 0.025 to 0.050 percent of citric acid and 0.15 to 0.30 percent of beta-cyclodextrin. The blueberries are crushed, subjected to enzymolysis, extracted, filtered and concentrated to obtain concentrated blueberry juice; the rhodiola rosea is crushed, extracted, filtered and concentrated to obtain concentrated rhodiola rosea juice; the concentrated blueberry juice, the concentrated rhodiola rosea juice, the white granulated sugar and the beta-cyclodextrin are mixed, blended, filtered, canned and sterilized to prepare the composite oral liquid. The blueberry and rhodiola rosea composite oral liquid is simple in preparation process and thick in fruity taste, has a remarkable anti-fatigue effect, and can meet the requirement of a customer on an anti-fatigue product.

Description

Blueberry rhodiola root composite oral liquid and preparation method thereof
Technical field
The present invention relates to oral liquid, specifically provides a kind of composite oral liquid and preparation method thereof.
Background technology
Blueberry, also known as cowberry, are the most abundant species of nutrient content in cowberry platymiscium, rich in carbohydrate, organic acid, various Vitamin, mineral matter and anthocyanidin, flavones, niacin isoreactivity composition.Active component in blueberry has antifatigue, antioxygen The effects such as changing, strengthen human immunologic function, preventing ocular diseases and protection eyesight, prevention of cardiovascular systemic disease.In recent years, I State blueberry industry is fast-developing, while blueberries are also into high yield period, but at present, blueberry is using the 60% of fresh pod yield as fresh Fruit is edible, and remaining 40% blueberries is processed, and blueberry essence, deep processed product are less.Rhodiola root be Crassulaceae rhodiola for many years Sward sheet or semishrub plant, contain various bioactivators in rhodiola plant, mainly there is flavonoids, glycoside, alkaloid Class, Coumarins etc., with significant antifatigue, anti anoxia, anti-ageing physiological function of waiting for a long time.
Oral liquid is the liquid preparation for oral administration of Jing extra packages, with taking dose it is little, absorb very fast, steady quality, take Band and taking convenience, it is easy to maintain the advantages of, be rapidly developed in recent years.
Now social most people is acted in a kind of inferior health, the exactly one of relatively more concerned aspect of fatigue. Fatigue refers to that organism physiology process can not continue its function and can not maintain predetermined exercise intensity in a specified level or each organ. Investigate according to the World Health Organization, close 40% crowd in the whole world is in fatigue state.Therefore a mouth with anti-fatigue effect is developed Liquid is taken, the species of oral liquid medicine not only can be increased, demand of the consumer to anti-fatigue product can be met again.
The content of the invention
The purpose of the present invention is:Blueberry rhodiola root composite oral liquid and preparation method thereof, the letter of oral liquid manufacture craft are provided It is single, with significant anti-fatigue effect.
The effect of each component in the present invention is:
In described Blueberry containing abundant anthocyanidin, polysaccharide, flavones and multivitamin, superoxide dismutase, Mineral matter and other components, with anti-oxidant, anti-aging, protection eyesight and reduce cardiovascular and cerebrovascular disease the effects such as;Its effect is:Blueberry Polysaccharide and anthocyanidin have antifatigue effect, used as the antifatigue composition that oral liquid is main;
Containing various bioactivators such as rhodioside, flavones, alkaloid, polysaccharide in described rhodiola plant, with anti- The effects such as aging, antifatigue, anti anoxia, anti-aging;Its effect is:Rhodioside has antifatigue effect, used as oral liquid master The antifatigue composition wanted;
Described white granulated sugar is a kind of common sweetener, and its effect is:Improve the mouthfeel of oral liquid;
Described citric acid is a kind of common acid, and its effect is:Improve the flavour of oral liquid;
Described cycloheptaamylose is with β -1,4- by made by starch is extracted Jing after microbial enzyme effect by 7 glucose residues The ring that glycosidic bond is bonded.Cycloheptaamylose is novel molecular lapping, can form inclusion with multiple compounds multiple Compound, with stable, solubilized, sustained release, emulsification, it is anti-oxidant, shelter the effect such as peculiar smell, its effect is:Suitably cover rhodiola root bitter Astringent taste.
It is an advantage of the invention that:Blueberry rhodiola root composite oral liquid is easy to use, manufacture craft simple, active component content Height, antifatigue effect is notable;Demand of the consumer to anti-fatigue product can be met, and improve the economic worth of blueberry.
Specific embodiment
Blueberry rhodiola root composite oral liquid, is made up of per 100 milliliters of oral liquids the raw material of following weight range:Blueberry 30% ~ 80%th, rhodiola root 10% ~ 15%, white granulated sugar 6% ~ 10%, citric acid 0.025% ~ 0.050% and the % of beta-schardinger dextrin 0.15% ~ 0.30, surplus It is distilled water.
Described is made up per 100 milliliters of oral liquids of the raw material of following preferred weight value:The g of blueberry 50, rhodiola root 10 G, the g of white granulated sugar 8, the g of citric acid 0.025, the g of beta-schardinger dextrin 0.2, surplus is distilled water.
Described blueberry, rhodiola root, white granulated sugar, citric acid, beta-schardinger dextrin, distilled water are commercially available prod.
The specific implementation method for making oral liquid based on above-mentioned component is as follows:
Embodiment one:The g of blueberry 50 beating crusher machines are weighed, 0.25 g pectinase enzymatic hydrolysis are added, hydrolysis temperature is 45 DEG C, enzyme The solution time is 3h;After enzymolysis, gone out enzyme 5min with 95 DEG C of water-baths, be cooled to room temperature;With the EtOH Sonicate ripple that 300 mL concentration are 60% Extract, extraction time is 45min, ultrasonic power is 280 W, extract vacuum filtration, the clarified solution rotary evaporation for obtaining Device is concentrated in vacuo, is concentrated into 50 mL, and with the filter-cloth filtering of 120 mesh, filtrate is standby;The g of rhodiola root 10 crushing is taken, 80 mesh sieve are crossed Sieved, ultrasonic wave extraction 2 times, 100 mL distilled water are added every time, extraction time is 20 min, and ultrasonic power is 500 W, merges extract, and extract vacuum filtration, the clarified solution for obtaining is concentrated in vacuo with rotary evaporator, is concentrated into 20 mL, uses The filter-cloth filtering of 120 mesh, filtrate is standby;A certain amount of sucrose is weighed, it is 50% to add enough distilled water to prepare mass fraction Syrup, heating while stirring makes sucrose fully dissolve, standby with the filter-cloth filtering removal of impurities of 200 mesh after cooling;Weigh a certain amount of Citric acid, adds enough distilled water to prepare the citric acid solution that mass fraction is 50%, and stirring makes citric acid fully dissolve, and uses The filter-cloth filtering removal of impurities of 200 mesh, it is standby;The mL of rhodiola root inspissated juice 20 and the stirring of 0.2 g beta-schardinger dextrins that handle well will be taken, be mixed Close uniform;The mL of blueberry inspissated juice 50, the 50% white sand sugar juice 16mL and mL of 50% citric acid solution 0.05 are added, are well mixed, 100mL is settled to distilled water;By mixed liquor under the conditions of 5000 r/min the min of centrifugal filtration 20;Obtained oral liquid is stood In carving filling to clean cillin bottle, Jing ultra high temperature short time sterilizations(135 DEG C, maintain 5S)Afterwards, be sequentially placed into 80 DEG C, 60 DEG C, Cooling is classified in 40 DEG C of water and under room temperature condition, is got product.The oral liquid be aubergine liquid, clear, with blueberry Fruital and rhodiola root peculiar fragrance;Anthocyanidin content is 150 mg/100mL, and Determination of Salidroside is 100 mg/100mL; Blueberry rhodiola root composite oral liquid can improve the mice burden swimming time 65%;Hepatic glycogen content improves 39% in mouse body, inose Former content improves 20%, and blood urea nitrogen content reduces by 6%, and Serum lactic acid content reduces by 25%.Adult drinks daily 20mL blueberry rhodiola roots Composite oral liquid, you can have significant antifatigue effect.
Embodiment two:The mL of rhodiola root inspissated juice 25 is obtained with the method for embodiment one to mix with 0.25 g beta-schardinger dextrins It is even;The mL of blueberry inspissated juice 50, the 50% white sand sugar juice 18mL and mL of 50% citric acid solution 0.05 are added, is well mixed, with steaming Distilled water is settled to 100mL;By mixed liquor under the conditions of 5000 r/min the min of centrifugal filtration 20;Obtained oral liquid is filled at once In being filled to the cillin bottle of cleaning, Jing ultra high temperature short time sterilizations(135 DEG C, maintain 5S)Afterwards, it is sequentially placed into 80 DEG C, 60 DEG C, 40 DEG C Cooling is classified in water and under room temperature condition, is got product.The oral liquid be aubergine liquid, clear, the fruit with blueberry The peculiar fragrance of fragrant and rhodiola root;Anthocyanidin content is 148 mg/100mL, and Determination of Salidroside is 118 mg/100mL;Blueberry Rhodiola root composite oral liquid can improve the mice burden swimming time 68%;Hepatic glycogen content improves 35% in mouse body, and muscle glycogen contains Amount improves 23%, and blood urea nitrogen content reduces by 10%, and Serum lactic acid content reduces by 27%.Adult drinks daily 20mL blueberries rhodiola root and answers Close oral liquid, you can have significant antifatigue effect.
Embodiment three:Mixed with 0.25 g beta-schardinger dextrins with the mL of rhodiola root inspissated juice 25 obtained in the method for embodiment one Uniformly;The mL of blueberry inspissated juice 60, the mL of 50% white sand sugar juice 20 and the mL of 50% citric acid solution 0.06 are added, are well mixed, 100mL is settled to distilled water;By mixed liquor under the conditions of 5000 r/min the min of centrifugal filtration 20;Obtained oral liquid is stood In carving filling to clean cillin bottle, Jing ultra high temperature short time sterilizations(135 DEG C, maintain 5S)Afterwards, be sequentially placed into 80 DEG C, 60 DEG C, Cooling is classified in 40 DEG C of water and under room temperature condition, is got product.The oral liquid be aubergine liquid, clear, with blueberry Unique fruital and rhodiola root peculiar fragrance;Anthocyanidin content is 176 mg/100mL, and Determination of Salidroside is 121 mg/ 100mL;Blueberry rhodiola root composite oral liquid can improve the mice burden swimming time 72%;Hepatic glycogen content is improved in mouse body 41%, muscle glycogen content improves 30%, and blood urea nitrogen content reduces by 14%, and Serum lactic acid content reduces by 31%.Adult drinks daily 20mL Blueberry rhodiola root composite oral liquid, you can have significant antifatigue effect.
Described ultrasonic cell disruptor is can to produce strong vibration using ultrasonic wave, accelerates active ingredient to enter Solvent, so as to improve recovery rate, ultrasonic wave extraction(Also referred to as ultrasonic extraction)It has that Extracting temperature is low, recovery rate is high, carries Time short unique advantage is taken, is widely used in the extraction of Chinese medicine and various animal and plant effective contents, substitute tradition shearing work Process, realizes that efficient, energy-saving and environmental protection formula is extracted, and ultrasonic wave extraction is mechanical effect, the cavitation effect having using ultrasonic wave And fuel factor, by increasing movement velocity, the penetration power of increase medium of medium molecule to extract biological effective components.
Blueberry rhodiola root composite oral liquid of the present invention is easy to use, manufacture craft is simple, active component content is high, antifatigue Effect is significant, is a kind of oral liquor with very strong development potentiality.

Claims (3)

1. a kind of blueberry rhodiola root composite oral liquid, is characterized in that the weight proportion that raw material is constituted is:Blueberry 30% ~ 80%, red scape Its 10% ~ 15%, white granulated sugar 6% ~ 10%, citric acid 0.025% ~ 0.050% and the % of beta-schardinger dextrin 0.15% ~ 0.30, surplus is distillation Water.
2. blueberry rhodiola root composite oral liquid according to claim 1, it is characterised in that:Per 100 milliliters of oral liquids by with The raw material of lower weight is made:The g of blueberry 50, the g of rhodiola root 10, the g of white granulated sugar 8, the g of citric acid 0.025, beta-schardinger dextrin 0.20 G, surplus is distilled water.
3. the preparation method of the blueberry rhodiola root composite oral liquid described in claim 1 or 2 is made, it is characterised in that the compound mouth Taking the preparation process of liquid includes:
(1)Prepare blueberry inspissated juice:The g of blueberry 50 beating crusher machines, 0.25 g pectinase enzymatic hydrolysis of addition are taken, hydrolysis temperature is 45 DEG C, enzymolysis time is 3h;95 DEG C of water-baths are gone out enzyme, are cooled to room temperature;Extracted with the EtOH Sonicate ripple that 300 mL concentration are 60%, Extraction time is 45min, and ultrasonic power is 280 W;Filter, the clarified solution for obtaining is concentrated in vacuo with rotary evaporator, it is dense 50 mL are reduced to, with the filter-cloth filtering of 120 mesh, filtrate is standby;
(2)Prepare rhodiola root inspissated juice:Take the g of rhodiola root 10 and crushed 80 mesh sieve, ultrasonic wave extraction 2 times adds every time 100 ML distilled water, extraction time is 20 min, and ultrasonic power is 500 W, merges extract, and with rotary evaporator 20 are concentrated into ML, with the filter-cloth filtering of 120 mesh, filtrate is standby;
(3)Mixing:Rhodiola root inspissated juice and beta-schardinger dextrin are uniformly mixed;Add blueberry inspissated juice, white sand sugar juice, Citric acid solution, is well mixed;
(4)Filter:By oral liquid under the conditions of 5000 r/min the min of centrifugal filtration 20;
(5)Filling, sterilization:By in oral liquid filling to cillin bottle, Jing ultra high temperature short time sterilizations(135 DEG C, maintain 5S)Afterwards, successively Put into 80 DEG C, 60 DEG C, in 40 DEG C of water and classification cooling under room temperature condition, get product.
CN201710034029.5A 2017-01-18 2017-01-18 Blueberry and rhodiola rosea composite oral liquid and preparation method thereof Pending CN106617069A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110236039A (en) * 2019-06-14 2019-09-17 昆明科晔生物技术有限公司 A kind of antifatigue white fragrant fruit beverage and preparation method thereof of refreshing oneself
CN112618652A (en) * 2020-12-25 2021-04-09 皖西学院 Stachys polysaccharide oral liquid and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091959A (en) * 1993-03-06 1994-09-14 西藏自治区生物资源开发研究中心 Xizang Rhodiola root oral liquid and preparation technology thereof
CN1915112A (en) * 2006-09-06 2007-02-21 大连轻工业学院 Method for preparing nutrient oral liquid of blueberries raw juice
CN103462148A (en) * 2013-08-27 2013-12-25 安徽农业大学 Preparation method of vaccimium spp. juice with high anthocyanin content
CN105949166A (en) * 2016-07-13 2016-09-21 吉林省普蓝高科技有限公司 Extraction method for blueberry anthocyanin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091959A (en) * 1993-03-06 1994-09-14 西藏自治区生物资源开发研究中心 Xizang Rhodiola root oral liquid and preparation technology thereof
CN1915112A (en) * 2006-09-06 2007-02-21 大连轻工业学院 Method for preparing nutrient oral liquid of blueberries raw juice
CN103462148A (en) * 2013-08-27 2013-12-25 安徽农业大学 Preparation method of vaccimium spp. juice with high anthocyanin content
CN105949166A (en) * 2016-07-13 2016-09-21 吉林省普蓝高科技有限公司 Extraction method for blueberry anthocyanin

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110236039A (en) * 2019-06-14 2019-09-17 昆明科晔生物技术有限公司 A kind of antifatigue white fragrant fruit beverage and preparation method thereof of refreshing oneself
CN112618652A (en) * 2020-12-25 2021-04-09 皖西学院 Stachys polysaccharide oral liquid and preparation method thereof

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