CN106606757A

CN106606757A - Medicine for treating infantile lung-heat type cough and preparation method thereof

Info

Publication number: CN106606757A
Application number: CN201510702397.3A
Authority: CN
Inventors: 陈修仕
Original assignee: GUIZHOU RUNSHENG PHARMACEUTICAL Co Ltd
Current assignee: GUIZHOU RUNSHENG PHARMACEUTICAL Co Ltd
Priority date: 2015-10-26
Filing date: 2015-10-26
Publication date: 2017-05-03

Abstract

The invention discloses a medicine for treating infantile cough and a preparation method thereof, wherein the medicine is mainly prepared from pinellia ternate, apricot kernel, radix asteris, white atractylodes rhizome, poria cocos, cassia twig, liquorice, dried tangerine or orange peel, fructus schisandrae, bombyx batryticatus and dried ginger. All the raw materials have good synergistic effect, and can be used for treating infantile cough; the medicine has the advantages of obvious curative effect, short treatment period, safety, and no side effects.

Description

It is a kind of to treat medicine of cough with lung heat of children and preparation method thereof

Technical field

The present invention relates to a kind of treat medicine of cough with lung heat of children and preparation method thereof, belong to the field of medicine technology.

Technical background

Cough is a kind of protectiveness respiratory reflex action of human body, by coughre flex can effectively remove secretions in respiratory tract or Into the foreign body of air flue.But under pathological state, such as long-term, frequent, violent cough has a strong impact on the daily life of patient.Pathology shape Cough under state can cause respiratory tract hemorrhage or even cause the symptoms such as laryngalgia, hoarseness and breathing myalgia.In the traditional Chinese medical science, cough refer to because For factors such as diseases caused by exogenous pathogenic factor or internal injuries, cause impaired depurative descending of lung QI, abnormal rising of lung-QI impact air flue and sending coughs sound or with coughing up phlegm as Clinical symptoms A kind of disease.Ancient Chinese medicine doctor is referred to as coughing by sound without expectorant, there is that expectorant is noiseless to be referred to as coughing, and has the cough of the sound meaning of expectorant.Clinically it mostly is Expectorant sound is simultaneously shown in, it is difficult to it is well-separated, therefore to cough and claim.With air pollution in recent years, increasingly serious and people smoke, stay up late Prevailing etc. unsound life style, the sickness rate more and more higher in crowd of coughing is caused greatly to people's physical and mental health Threat.

Respiratory tract infection is the first reason for causing less than 5 years old death of child, the commonly encountered diseases, frequently-occurring disease as department of pediatrics, causes and exhales The cause of disease for inhaling road infection is but difficult clearly.Doctor trained in Western medicine research shows that 90% or so is caused by virus, and bacterium infection is often secondary to viral sense It is clinically common with antibacterial, virus mixed infection after dye.Cough with lung heat of children is one kind the most common in respiratory tract infection Type, is that pathogenic heat accumulate lung, and lung is burnt by pyretic toxicity because wind-heat evil toxin violates lung, or wind and coldization heat, loses, expectorant heat clear respectful in a surname's drop Inside causes a kind of disease that intrapulmonary is hot and suffocating, Lung Qi obstraction appearance is based on generating heat, cough.

For above-mentioned disease, although have much currently used for the medicine for the treatment of cough with lung heat of children, but most drug drug effect is slow Slowly, treatment cycle is long, large side effects.

The content of the invention：

It is an object of the present invention to provide a kind of treat medicine of cough with lung heat of children and preparation method thereof.The medicine can be used for Treatment cough with lung heat of children；Suitable child administration, evident in efficacy, treatment cycle is short, has no side effect safely.

To solve above-mentioned technical problem, the present invention employs the following technical solutions realization：A kind of medicine for treating cough with lung heat of children, Calculate by weight, mainly by Fructus Forsythiae 15-25 parts, Flos Lonicerae 15-25 parts, Radix Isatidis 1-10 parts, Radix Peucedani 10-20 parts, Bombyx Batryticatus 1-10 parts, Radix Glycyrrhizae 10-20 parts, Ramulus Cinnamomi 1-10 parts, Radix Glycyrrhizae 25-35 parts, Pericarpium Citri Reticulatae 30-40 parts, Fructus Schisandrae Chinensis 20-30 parts, Bombyx Batryticatus 1-10 parts and Rhizoma Zingiberiss 1-10 parts are made.

In the medicine of aforesaid treatment cough with lung heat of children, calculate by weight, mainly by 20 parts of Fructus Forsythiae, 20 parts of Flos Lonicerae, plate 5 parts of blue root, 15 parts of Radix Peucedani, 5 parts of Bombyx Batryticatus, 15 parts of Radix Glycyrrhizae, 5 parts of Ramulus Cinnamomi, 30 parts of Radix Glycyrrhizae, 35 parts of Pericarpium Citri Reticulatae, the five tastes 5 parts of 25 parts of son, 5 parts of Bombyx Batryticatus and Rhizoma Zingiberiss are made.

A kind of manufacture method of the medicine of aforementioned therapies cough with lung heat of children, takes said medicine, can add adjuvant, it is also possible to be not added with Adjuvant, makes oral formulations.

In the manufacture method of the medicine of aforementioned therapies cough with lung heat of children, the oral formulations be granule, capsule, tablet, Pill, powder or cream.

In the manufacture method of the medicine of aforementioned therapies cough with lung heat of children, the granule so makes：Said medicine is taken, plus 10 Again amount decocting is boiled 3 times, and each 1.5h is filtered, and merges decoction liquor, and relative density is 1.15-1.20 when being condensed into 50-60 DEG C Extractum, the starch and 20% dextrine powder mixing granulation of extractum and extractum amount 20% are dried, obtain final product.

In the manufacture method of the medicine of aforementioned therapies cough with lung heat of children, the manufacture method of the capsule is：Take said medicine, With the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, and filtrate recycling ethanol is simultaneously condensed into 50-60 DEG C When relative density be the extractum of 1.20-1.25, separately take the starch and 0.7% magnesium stearate of extractum amount 30% and mix with extractum, use 60% alcohol granulation, dry, pulverize, and fill capsule, obtain final product.

In the manufacture method of the medicine of aforementioned therapies cough with lung heat of children, the manufacture method of the tablet is：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, and each 1.5h is filtered, and merges decoction liquor, and relative density is 1.15-1.20 when being condensed into 50-60 DEG C Extractum, the starch of extractum and above-mentioned mixed powder and extractum amount 20% mixes, and tabletting, film coating is obtained final product.

Compared with prior art, medicine of the present invention is mainly by Fructus Forsythiae, Flos Lonicerae, Radix Isatidis, Radix Peucedani, Bombyx Batryticatus, Radix Glycyrrhizae, Ramulus Cinnamomi, Radix Glycyrrhizae, Pericarpium Citri Reticulatae, Fructus Schisandrae Chinensis, Bombyx Batryticatus and Rhizoma Zingiberiss are made.Each raw material has good synergism in prescription, Can be used for treatment cough；Evident in efficacy, treatment cycle is short, has no side effect safely.

Treatment example：

Liu, female, 1 years old, on January 28th, 2014 examined

Hope：White both sides are yellow in red tongue tongue, and front middle tongue is on the low side.Hear：Cough sound.Ask：Start after being under the weather cough, afternoon with 1 point or so of evening very, with breathing heavily, when have hypopnea, have expectorant, yellow skin is white, feels itching throat, and two sides of body do not relax, watery nasal discharge, hyperhidrosis. Cut：Right cun of arteries and veins is sliding to close that slide rule is heavy to be slided, and left cun sliding to close that heavy slide rule is heavy to be slided.This patient side of body rib is not relaxed, and night is coughed very, is that Liver Channel is not smooth Clear proof, the lateral deviation of tongue two is yellow, is performance that is strongly fragrant and changing heat, and its expectorant yellow skin is alternate in vain, and the right cun cunning of arteries and veins is lung meridian cold-phlegm Performance.Treatment is worked as with the cold-phlegm of temperatureization lung, clear profit stagnated heat of liver channel.Its mechanism being under the weather is complied with first, gives relieving exterior syndrome and dispelling cold, The XIAOQINGLONG TANG of warming for resolving cold-phlegm adds Rhizoma Belamcandae, Radix Saposhnikoviae, Radix Asteriss, the Radix Stemonae, Radix Platycodoniss.Meanwhile, its mechanism with stagnated heat of liver channel is complied with, Give ZHIKE SAN.After five days, recovery from illness.

Zhang, female, 3 years old, on June 10th, 2014 examined

Hope：The dark stagnant network of tongue is thin, and thin fur is slided.Hear：Cough sound.Ask：It is under the weather at the beginning of 2 months, coughing occurs to April in protracted course of disease Cough, cough recently increases, and feeling has white expectorant and glue, feel itching throat, then swallow viscous unfavorable at nightfall.Coughed last night and even woke up, 2-3 points When it is most heavy, food is received still, even to feel xerostomia, feels that antiperspirant is few.Cut：The right CUN-pulse being moderate chi of arteries and veins sinks weak, and left cun of bean closes the little string of slow tape.This Patient coughs very at night, and itching throat expectorant glues, and points out Liver Channel not smooth and has hot and suffocating.Its expectorant color is white, and right CUN-pulse being moderate is the performance of lung meridian cold-phlegm. Treatment is when with the cold-phlegm of temperatureization lung, clear profit stagnated heat of liver channel is not solved less first along its antiperspirant for exterior cold, gives relieving exterior syndrome and dispelling cold, Wen Huahan The XIAOQINGLONG TANG of expectorant adds processs Radix Asteriss, processs coltsfoot, Bombyx Batryticatus, Rhizoma Belamcandae, Semen Ginkgo.For the feature that with the passing of time expectorant glues, give sharp expectorant Fresh Succus Bambusae, in Wen Huazhong burnt Radix Aconiti Lateralis Preparata reason, assists resolving sputum jointly.Simultaneously as it is with stagnated heat of liver channel, coordinate ZHIKE SAN. After seven days, recovery from illness.

Invention is further described with reference to embodiment, but is not intended as the foundation limited the present invention.

Specific embodiment：

Embodiment 1.

Formula：It is Fructus Forsythiae 20g, Flos Lonicerae 20g, Radix Isatidis 5g, Radix Peucedani 15g, Bombyx Batryticatus 5g, Radix Glycyrrhizae 15g, Ramulus Cinnamomi 5g, sweet Careless 30g, Pericarpium Citri Reticulatae 35g, Fructus Schisandrae Chinensis 25g, Bombyx Batryticatus 5g and Rhizoma Zingiberiss 5g.

Technique：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, is condensed into 50-60 DEG C When relative density for 1.15-1.20 extractum, the starch and 20% dextrine powder mixing granulation of extractum and extractum amount 20% is dried, Obtain final product granule.

Specification：0.5g/ grains.

Usage and dosage：Every time 2-3 grains, daily 2-3 time.

Claims

1. a kind of medicine for treating cough with lung heat of children, it is characterised in that：Calculate by weight, mainly by Fructus Forsythiae 15-25 parts, Flos Lonicerae 15-25 parts, Radix Isatidis 1-10 parts, Radix Peucedani 10-20 parts, Bombyx Batryticatus 1-10 parts, Radix Glycyrrhizae 10-20 parts, Ramulus Cinnamomi 1-10 parts, Radix Glycyrrhizae 25-35 parts, Pericarpium Citri Reticulatae 30-40 parts, Fructus Schisandrae Chinensis 20-30 parts, Bombyx Batryticatus 1-10 parts and Rhizoma Zingiberiss 1-10 parts are made.

2. the medicine of cough with lung heat of children is treated as claimed in claim 1, it is characterised in that：Calculate by weight, mainly by Fructus Forsythiae 20 parts, 20 parts of Flos Lonicerae, 5 parts of Radix Isatidis, 15 parts of Radix Peucedani, 5 parts of Bombyx Batryticatus, 15 parts of Radix Glycyrrhizae, 5 parts of Ramulus Cinnamomi, Radix Glycyrrhizae 30 5 parts of part, 35 parts of Pericarpium Citri Reticulatae, 25 parts of Fructus Schisandrae Chinensis, 5 parts of Bombyx Batryticatus and Rhizoma Zingiberiss are made.

3. it is a kind of it is as claimed in claim 1 or 2 treatment cough with lung heat of children medicine manufacture method, it is characterised in that：Take above-mentioned medicine Thing, can add adjuvant, it is also possible to be not added with adjuvant, make oral formulations.

4. the manufacture method for treating the medicine of cough with lung heat of children as claimed in claim 3, it is characterised in that：The oral formulations are Granule, capsule, tablet, pill, powder or cream.

5. the manufacture method for treating the medicine of cough with lung heat of children as claimed in claim 4, it is characterised in that：The granule is so Make：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, is condensed into 50-60 DEG C When relative density for 1.15-1.20 extractum, the starch and 20% dextrine powder mixing granulation of extractum and extractum amount 20% is dried, Obtain final product.

6. the manufacture method for treating the medicine of cough with lung heat of children as claimed in claim 4, it is characterised in that：The system of the capsule It is as method：Said medicine is taken, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filter Relative density is the extractum of 1.20-1.25 when liquid reclaims ethanol and is condensed into 50-60 DEG C, separately takes the starch and 0.7% of extractum amount 30% Magnesium stearate and extractum mix, with 60% alcohol granulation, dry, pulverize, fill capsule, obtain final product.

7. the manufacture method for treating the medicine of cough with lung heat of children as claimed in claim 4, it is characterised in that：The making of the tablet Method is：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, is condensed into 50-60 DEG C When relative density for 1.15-1.20 extractum, the starch of extractum and above-mentioned mixed powder and extractum amount 20% mixes, and tabletting is wrapped thin Film clothing, obtains final product.