CN106606550A - Traditional Chinese medicine composition capable of moistening intestines and relaxing bowels and preparation method thereof, and health food - Google Patents
Traditional Chinese medicine composition capable of moistening intestines and relaxing bowels and preparation method thereof, and health food Download PDFInfo
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- CN106606550A CN106606550A CN201611158806.9A CN201611158806A CN106606550A CN 106606550 A CN106606550 A CN 106606550A CN 201611158806 A CN201611158806 A CN 201611158806A CN 106606550 A CN106606550 A CN 106606550A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention provides a traditional Chinese medicine composition capable of moistening the intestines and relaxing the bowels, belonging to the field of Chinese herbal compounds. The traditional Chinese medicine composition is prepared from the following raw materials by weight: 15 to 20 parts of senna leaf, 10 to 16 parts of fruit of ford manglietia, 6 to 12 parts of Chinese angelica, 6 to 12 parts of cistanche, 6 to 10 parts of licorice root and 6 to 10 parts of honey. The traditional Chinese medicine composition provided by the invention is capable of benefiting lung qi, clearing away deficiency fire and dredging the intestinal tracts. The invention also discloses a preparation method for the traditional Chinese medicine composition. The preparation method comprises the following steps: crushing the Chinese angelica into powder; separately extracting the senna leaf, cistanche, fruit of ford manglietia and licorice root so as to obtain liquid extracts, combining the liquid extracts to obtain a liquid extract mixture and concentrating the liquid extract mixture so as to obtain extract paste; and mixing the powder, the extract paste and the honey so as to obtain the traditional Chinese medicine composition. The method can effectively extract active components in the raw materials.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, and more particularly to a kind of Chinese medicine composition of loosening bowel to relieve constipation, its preparation side
Method and health food.
Background technology
Constipation is a kind of common disease, the increase, daily schedule recently as people's life stress it is irregular with
And diet deflection is pungent, the sickness rate of China's constipation is further promoted to 30% or so.Constipation patient is due to faecal retention intestinal
It is difficult to discharge, abdominal part distension, nausea, anorexia, food and the symptom such as tasteless can be produced, and cause hemorrhoid, anal fissure, proctoptosis and knot
The anorectal disease such as intestina diverticulum, while patient can also produce the symptoms such as dysphoria, irritability, insomnia, receive the life of people
Very big impact.
From from the perspective of the traditional Chinese medical science, the cause of disease of constipation mainly has following several：First, accumulated heat in gastrointestinal tract, consumption impairment of body fluid liquid, make intestinal
Dry and astringent to lose profit, excrement matter is dried, it is difficult to discharge, and forms constipation.2nd, depression and stagnation of QI, sorrow are pondered over, and damage of the spleen is depressed；Or it is depressed angry,
Stagnation of QI due to depression of the liver；Or sitting is moved less, disorder of QI movement can cause the internal organs stagnation of QI stagnant, lead to and drop not normal, and conduction dereliction of duty stops in waste matter, must not
It is descending, or be intended to just not go out, or go out and smooth, or constipation with dry stool, form constipation.3rd, YIN-cold stagnates, addiction to uncooked and cold food, and stagnate gastrointestinal；
Or diseases caused by exogenous pathogenic factor cold-evil, direct attack the intestines and stomach；Or cross and take cold and cool, knot in YIN-cold can cause yin-cold excess, and stagnate gastrointestinal, conducts not normal, grain
The dregs of rice are not all right, form constipation.4th, deficiency of vital energy sun declines, improper diet and overtiredness, and taste are damaged；Or ferritic is weak, YANG QI deficiency；Or it is old,
Deficiency of vital energy sun declines；Or prolonged illness puerperal, healthy energy is multiple；Or eating cold and uncooked food excessively, damage yang-energy；Or bitter cold is sent an expedition against, impairment of YANG gas consumption can cause
Deficiency of vital energy sun declines, and then large intestine conduction is powerless for the deficiency of vital energy, and then intestinal loses in warm yang deficiency, knot in YIN-cold, just under it is powerless, prolong defecation time
It is long, form constipation.5th, deficiency of both YIN-fluid and blood, the ferritic deficiency of YIN；Or body fluid deficiency insufficiency of blood；Or puerperal after being ill, cloudy blood deficiency is few；Or lose blood and take antiperspirant by force, hinder
Tianjin exhaustion of blood；Or year is high weak, deficiency of YIN-blood；Or the pungent perfume of surfeit is scorching, the cloudy blood of loss can cause deficiency of both YIN-fluid and blood, and blood deficiency is then big
Intestinal is not flourish, and then large intestine is dry and astringent for yin deficiency, and intestinal loses profit, and constipation with dry stool is just lower difficult, forms constipation.
Above-mentioned five kinds of causes of disease usually occur simultaneously or mutually convert, and improve constipation diagnosis and the difficulty treated.It is existing
Constipation therapy method mostly adopts the compositions such as cathartic, the lactulose for such as adopting in doctor trained in Western medicine, glycerol, Sorbitol, adopts in the traditional Chinese medical science
Fructus Cannabis Bolus, the formula such as CHENGQI TANG, these cathartic are using rear easy initiation serious dehydration, nausea, abdominal distention, stomachache, diarrhoea, mistake
It is quick to wait side effect and untoward reaction, the more women of old man, child and the cold body constitution to having a delicate constitution simultaneously not to apply to.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition of loosening bowel to relieve constipation, its Small side effects is evident in efficacy, can
Effectively prevention and treatment constipation.
Another object of the present invention is to provide a kind of preparation method of the Chinese medicine composition of loosening bowel to relieve constipation, the original of the method
Material utilization rate is high, and can effectively remove the harmful components in raw material.
Another object of the present invention is to provide a kind of health food of prevention and treatment constipation.
The present invention solves its technical problem and employs the following technical solutions to realize.
The present invention proposes a kind of Chinese medicine composition of loosening bowel to relieve constipation, and which is prepared from the following materials, and counts by weight,
Raw material includes：15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6-10 parts Radix Glycyrrhizae and 6-
10 parts of Mel.
Further, in present pre-ferred embodiments, count by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation
Including：15-20 part Folium Sennae, 12-14 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 8-10 parts Radix Glycyrrhizae and 8-10 parts
Mel.
Further, in present pre-ferred embodiments, count by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation
Also include 6-12 part heat clearing away components, heat clearing away component includes Fructus Momordicae, Radix Ophiopogonis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Herba Artemisiae, at least one in Flos Sophorae.
Further, in present pre-ferred embodiments, count by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation
Including：15-20 part Folium Sennae, 12-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6-8 part Radix Glycyrrhizaes, 8-10 part honeybees
Honey, 2-4 part Fructus Momordicaes.
Further, in present pre-ferred embodiments, count by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation
Also include that 6-12 parts nourish component, nourishing component includes at least one in Colla Corii Asini, Semen Sesami Nigrum, Fructus Lycii.
Further, in present pre-ferred embodiments, count by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation
Including：15-20 part Folium Sennae, 10-14 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6-8 part Radix Glycyrrhizaes, 8-10 part honeybees
Honey, 2-4 part Colla Corii Asini.
The present invention proposes a kind of preparation method of the Chinese medicine composition of loosening bowel to relieve constipation, and which includes：
Prepare raw material 15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part meat deserts by weight
Rong, 6-10 parts Radix Glycyrrhizae and 6-10 part Mel；
Radix Angelicae Sinensis are crushed, powder is obtained；
Folium Sennae is extracted using water extraction, Senna fruit leaf extract is obtained；Fructus Manglietiae fordianae is extracted using water extraction, wood is obtained
Lotus fruit extracting solution；Herba Cistanches are extracted using water extraction, Herba Cistanches extracting solution is obtained；Radix Glycyrrhizae is extracted using water extraction, is obtained
Radix Glycyrrhizae extract；Senna fruit leaf extract, Fructus Manglietiae fordianae extracting solution, Herba Cistanches extracting solution and Radix Glycyrrhizae extract are merged and obtains extracting solution
Mixture, and it is concentrated to give extract mastic；
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent, granule, pill, tablet or capsule
Agent.
Further, in present pre-ferred embodiments, during the above-mentioned raw material of preparation by weight, raw material also includes 2-4
Portion Fructus Momordicae, 1-2 parts Radix Ophiopogonis, 1-2 part Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 1-2 part Flos Sophoraes, 1-2 part Herba Artemisiae；When extract mastic is prepared, by Radix Ophiopogonis, flood
Even, Flos Sophorae is extracted using water extraction respectively, obtains Radix Ophiopogonis extract, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Flos Sophorae extract；By Fructus Momordicae, Herba Artemisiae
Extracted using alcohol extracting method respectively, obtain Fructus Momordicae extracting solution, Herba Artemisiae extracting solution；Radix Ophiopogonis extract, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Flos Sophorae are carried
Take liquid, Fructus Momordicae extracting solution, Herba Artemisiae extracting solution and mix homogeneously with liquid mixture is extracted, and be concentrated to give extract mastic.
Further, in present pre-ferred embodiments, during the above-mentioned raw material of preparation by weight, raw material also includes 2-4
Part Colla Corii Asini, 2-4 parts Semen Sesami Nigrum and 2-4 part Fructus Lycii；When powder is prepared, Colla Corii Asini, Semen Sesami Nigrum, Fructus Lycii are crushed, and and powder
Radix Angelicae Sinensis mix homogeneously after broken, obtains powder.
The present invention proposes a kind of health food of prevention and treatment constipation, and which is by the Chinese medicine composition of above-mentioned loosening bowel to relieve constipation
1 is pressed with mixed grain rice:The weight of 4-10 is than mixing, and prepares.
The beneficial effect of the Chinese medicine composition and preparation method of the loosening bowel to relieve constipation of the embodiment of the present invention is：The loosening bowel to relieve constipation
Chinese medicine composition adopts rational drug matching, and with Folium Sennae as monarch, Fructus Manglietiae fordianae is minister, and Radix Angelicae Sinensis, Herba Cistanches are assistant, Radix Glycyrrhizae, honeybee
To make, obtained Chinese medicine composition has functions that lung benefiting gas, clear asthenic fire, logical intestinal to honey, effectively can prevent and treat just
It is secret, it is especially suitable for the body voids such as old man, child, women, YIN-cold body constitution crowd and uses.The preparation of the Chinese medicine composition of the loosening bowel to relieve constipation
Method effectively using the active component in raw material, and can remove the toxic and side effects of raw material.
Specific embodiment
To make purpose, technical scheme and the advantage of the embodiment of the present invention clearer, below will be in the embodiment of the present invention
Technical scheme be clearly and completely described.In embodiment, unreceipted actual conditions person, builds according to normal condition or manufacturer
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, are the conventional product that can pass through that commercially available purchase is obtained
Product.
Below the Chinese medicine composition and processing technology of the loosening bowel to relieve constipation of the embodiment of the present invention are specifically described.
The embodiment of the present invention provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and which is prepared from the following materials, by weight
Number meter, raw material include 15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6-10 part Radix Glycyrrhizaes
And 6-10 part Mel.Preferably, in present pre-ferred embodiments, count by weight, raw material includes：15-20 part Senna fruit
Leaf, 12-14 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 8-10 parts Radix Glycyrrhizae and 8-10 part Mel.
The Chinese medicine composition of the loosening bowel to relieve constipation that the present invention is provided, using rational drug matching, with Folium Sennae as monarch, Fructus Fici Pumilae
Fruit is minister, and, to help, Radix Glycyrrhizae, Mel are to make for Radix Angelicae Sinensis, Herba Cistanches；Wherein Folium Sennae, Fructus Manglietiae fordianae have functions that to expel the heat-evil, relieving constipation；When
Return, Herba Cistanches have functions that blood-nourishing blood enriching and yin nourishing YANG invigorating, loosening bowel to relieve constipation；Radix Glycyrrhizae has invigorating the spleen and replenishing QI, Cheongju thermal detoxifications, placed in the middle
Effect of mediation；Mel has functions that intestine moistening, invigorating middle warmer, removing toxic substances.Using Folium Sennae, Fructus Manglietiae fordianae, Radix Angelicae Sinensis, Herba Cistanches, Radix Glycyrrhizae, honeybee
Chinese medicine composition obtained in honey processing has functions that lung benefiting gas, clear asthenic fire, logical intestinal, intestinal stagnant for depression and stagnation of QI, the internal organs stagnation of QI
Stomach accumulated heat, consumption impairment of body fluid liquid and it is yin-cold excess, stagnate gastrointestinal produce constipation be respectively provided with good curative effect be adapted to old man, child,
The body voids such as women, YIN-cold body constitution crowd's life-time service.
It is further preferred that counting by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation also includes 6-12 part heat clearing away
Component, heat clearing away component include Fructus Momordicae, Radix Ophiopogonis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Herba Artemisiae, at least one in Flos Sophorae.Preferably, of the invention preferably real
Apply in example, count by weight, raw material includes 15-20 part Folium Sennae, 12-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part meat deserts
Rong, 6-8 part Radix Glycyrrhizaes, 8-10 part Mel, 2-4 part Fructus Momordicaes.Heat clearing away component has functions that heat clearing away, removing toxic substances, lung moistening, pathogenic fire purging, with
When Folium Sennae, Fructus Manglietiae fordianae, Radix Angelicae Sinensis, Herba Cistanches, Radix Glycyrrhizae, Mel are used cooperatively, be capable of auxiliary treating coprostasis produce gastrointestinal product knot,
Have blood in stool the symptoms such as hemorrhoidal bleeding, jaundice due to damp-heat.
It is further preferred that counting by weight, the raw material of the Chinese medicine composition of loosening bowel to relieve constipation is also nourished including 6-12 parts
Component, nourishing component includes at least one in Colla Corii Asini, Semen Sesami Nigrum, Fructus Lycii.Preferably, in present pre-ferred embodiments,
Count by weight, raw material includes：15-20 part Folium Sennae, 10-14 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6-8
Part Radix Glycyrrhizae, 8-10 part Mel, 2-4 part Colla Corii Asini.Nourish component and there is enriching blood and replenishing vital essence, nourshing Yin and drynsessmoistening prescription, with Folium Sennae, Fructus Fici Pumilae
Really, when Radix Angelicae Sinensis, Herba Cistanches, Radix Glycyrrhizae, Mel are used cooperatively, can effectively treat deficiency of vital energy sun and decline, YANG QI deficiency and yin deficiency blood
It is few, the constipation that deficiency of YIN-blood is produced, while there is nourishing and health preserving, liver and kidney tonifying, effect of conditioning body and mind.
The medicinal efficacy of above-mentioned primary raw material：
Folium Sennae, sweet in the mouth, hardship are cold in nature, return large intestine channel.Folium Sennae has stagnant, the relieving constipation of row of purging heat, effect of diuretic.For
Accumulation of heat stagnates, constipation stomachache, oedema turgor.
Fructus Manglietiae fordianae, acrid in the mouth are cool in nature, return lung, large intestine channel.There is relieving constipation, cough-relieving.Just close for excess-heat, Lao Rengan
Cough.
Radix Angelicae Sinensis, sweet in the mouth, pungent, warm in nature, Return liver, the heart, spleen channel, Radix Angelicae Sinensis have replenishing and activating blood, menstruction regulating and pain relieving, the work(of loosening bowel to relieve constipation
Effect.For blood deficiency and yellow complexion, dizziness palpitaition, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, carbuncle skin ulcer
Infectionss, dry constipation of intestines.
Herba Cistanches, it is sweet in the mouth, salty, it is warm in nature, return kidney, large intestine channel.Herba Cistanches have kidney-replenishing, and benefit essence is random, the work(of loosening bowel to relieve constipation
Effect.For insufficiency of kidney-YANG, blood and essence asthenia, sexual impotence are infertile, and soreness of the waist and knees, muscles and bones are powerless, dry constipation of intestines.
Radix Glycyrrhizae, sweet in the mouth are mild-natured, GUIXIN, lung, spleen, stomach.Radix Glycyrrhizae has invigorating the spleen and replenishing QI ， Cheongju thermal detoxifications, and expelling phlegm for arresting cough delays
Anxious pain relieving, effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction suddenly ache
Bitterly, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Mel, sweet in the mouth are mild-natured, return lung, spleen, large intestine channel.Mel has invigorating middle warmer, moisturizes, pain relieving, effect of removing toxic substances.External
In promoting tissue regeneration and ulcer healing, skin infection is not held back, burn due to hot liquid or fire.Interior empty bitterly for gastral cavity abdomen, dryness of the lung dry cough, dry constipation of intestines solve Aconitum poison of drug.
Fructus Momordicae, sweet in the mouth are cool in nature, return lung, large intestine channel.Fructus Momordicae has clearing heat and moistening lung, relieving sore throat to recover voice, the work(of laxation relieving constipation
Effect.For lung-heat type cough, pharyngalgia aphonia, dry constipation of intestines.
Radix Ophiopogonis, sweet in the mouth, slight bitter, cold nature, GUIXIN, lung, stomach.There is Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, effect of moistening lung clears away heart-fire.With
In dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.
Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), bitter in the mouth, sweet, cold in nature, return lung, the heart, Liver Channel.Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) has heat clearing away, removing toxic substances, dampness removing, suppressing the hyperactive liver, promoting the circulation of blood, regulating menstruation
Effect.For excessive thirst of generating heat, cough due to lung-heat, dizziness of having a headache, jaundice due to damp-heat, menoxenia, medicine food poisoning.
Herba Artemisiae, bitter in the mouth, pungent, cold in nature, Return liver, gallbladder meridian.Herba Artemisiae has clear Virtual hot, except hectic fever due to YIN-deficiency, solves summer-heat, preventing the attack (or recurrence) of malaria, jaundice eliminating
Effect.For pathogenic warmth impairment of YIN, night fever abating at dawn, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, pathogenic summer-heat heating, malaria cold and heat, jaundice due to damp-heat.
Flos Sophorae, bitter in the mouth, cold nature, Return liver, large intestine channel.Flos Sophorae has cooling blood for hemostasis, effect of purging liver-fire.For just
Blood, hemorrhoidal bleeding, dysentery, metrorrhagia are spitted blood, epistaxis, the hot hot eyes of liver, dizziness of having a headache.
Colla Corii Asini, sweet in the mouth are mild-natured, return lung, liver and kidney channel.Colla Corii Asini has YIN nourishing of enriching blood, and moisturizes, effect of hemostasis.For blood deficiency
It is sallow, dizziness palpitaition, flesh impotence is unable, dysphoria and insomnia, stirring-up of pathogenic wind in the interior resulting from deficiency, xeropulmonary cough, chronic cough spitting of blood, haematemesis hematuria, uterine bleeding of having blood in stool,
Vaginal bleeding during pregnancy.
Semen Sesami Nigrum, sweet in the mouth are mild-natured, Return liver, kidney, large intestine channel.Semen Sesami Nigrum has invigorating the liver and kidney, benefiting essence-blood, the dry effect of intestine moistening.
For blood and essence asthenia, dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dry constipation of intestines.
Fructus Lycii, sweet in the mouth are mild-natured, return liver and kidney channel.Fructus Lycii has nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight.For asthenia
Damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, Heat Diabetes, blood deficiency and yellow complexion, blurred vision.
A kind of preparation method of the Chinese medicine composition of loosening bowel to relieve constipation is present embodiments provided, is comprised the following steps：
Prepare raw material by weight：15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part meat deserts
Rong, 6-10 parts Radix Glycyrrhizae and 6-10 part Mel；
Radix Angelicae Sinensis were crushed into 100-200 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously after sieve, powder was obtained；
Folium Sennae is extracted using water extraction, Senna fruit leaf extract is obtained；Fructus Manglietiae fordianae is extracted using water extraction, wood is obtained
Lotus fruit extracting solution；Herba Cistanches are extracted using water extraction, Herba Cistanches extracting solution is obtained；Radix Glycyrrhizae is extracted using water extraction, is obtained
Radix Glycyrrhizae extract；Senna fruit leaf extract, Fructus Manglietiae fordianae extracting solution, Herba Cistanches extracting solution and Radix Glycyrrhizae extract are merged and obtains extracting solution
Mixture, and it is concentrated to give extract mastic；
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent, granule, pill, tablet or capsule
Agent.
In the technology of such scheme, the embodiment of the present invention additionally provides a kind of preparation of the Chinese medicine composition of loosening bowel to relieve constipation
Method, comprises the following steps：
Prepare raw material by weight：15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part meat deserts
Rong, 6-10 part Radix Glycyrrhizaes, 6-10 part Mel, 2-4 part Fructus Momordicaes, 1-2 parts Radix Ophiopogonis, 1-2 part Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 1-2 parts Herba Artemisiae and 1-2 part Chinese scholartrees
Flower.
Radix Angelicae Sinensis were crushed into 100-200 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously after sieve, powder was obtained；
Folium Sennae is extracted using water extraction, Senna fruit leaf extract is obtained；Fructus Manglietiae fordianae is extracted using water extraction, wood is obtained
Lotus fruit extracting solution；Herba Cistanches are extracted using water extraction, Herba Cistanches extracting solution is obtained；Radix Glycyrrhizae is extracted using water extraction, is obtained
Radix Glycyrrhizae extract；Radix Ophiopogonis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Flos Sophorae are extracted using water extraction respectively, Radix Ophiopogonis extract, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Flos Sophorae is obtained
Extracting solution, Fructus Momordicae, Herba Artemisiae are extracted using alcohol extracting method respectively, obtain Fructus Momordicae extracting solution, Herba Artemisiae extracting solution, Folium Sennae is carried
Take liquid, Fructus Manglietiae fordianae extracting solution, Herba Cistanches extracting solution, Radix Glycyrrhizae extract, Radix Ophiopogonis extract, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Flos Sophorae extract, sieve
Chinese fruit extracting solution, the merging of Herba Artemisiae extracting solution are obtained extracting liquid mixture, and are concentrated to give extract mastic.
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent, granule, pill, tablet or capsule
Agent.
In the technology of such scheme, the embodiment of the present invention additionally provides a kind of preparation of the Chinese medicine composition of loosening bowel to relieve constipation
Method, comprises the following steps：
Prepare raw material by weight：15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part meat deserts
Rong, 6-10 part Radix Glycyrrhizaes, 6-10 part Mel, 2-4 part Colla Corii Asini, 2-4 parts Semen Sesami Nigrum and 2-4 part Fructus Lycii.
Radix Angelicae Sinensis, Colla Corii Asini, Semen Sesami Nigrum and Fructus Lycii are crushed respectively, and crosses 100-200 mesh sieves, after the Radix Angelicae Sinensis after sieve, sieve
Colla Corii Asini, sieve after Semen Sesami Nigrum, sieve after Fructus Lycii mix homogeneously, obtain powder.
Folium Sennae is extracted using water extraction, Senna fruit leaf extract is obtained；Fructus Manglietiae fordianae is extracted using water extraction, wood is obtained
Lotus fruit extracting solution；Herba Cistanches are extracted using water extraction, Herba Cistanches extracting solution is obtained；Radix Glycyrrhizae is extracted using water extraction, is obtained
Radix Glycyrrhizae extract；Senna fruit leaf extract, Fructus Manglietiae fordianae extracting solution, Herba Cistanches extracting solution and Radix Glycyrrhizae extract are merged and obtains extracting solution
Mixture, and it is concentrated to give extract mastic；
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent, granule, pill, tablet or capsule
Agent.
Wherein, water extraction is by 1 by raw material and water:The mass ratio mixing of 5-10, and it is little that 1-2.5 is extracted at 50-80 DEG C
When, extract 1-2 time, be filtrated to get raw material extracting solution.Alcohol extracting method is by 1 by the ethanol of raw material and volumetric concentration 60-90%:2-5
Mass ratio mixing, and at 60-80 DEG C extract 1-2 hours, extract 1-2 time, separating alcohol after filtration, obtain raw material extract
Liquid.
The preparation method of the Chinese medicine composition of the loosening bowel to relieve constipation that the present embodiment is provided, by Radix Angelicae Sinensis, Colla Corii Asini, Semen Sesami Nigrum and Fructus Lycii
Son etc. has no toxic side effect, and the abundant component of active component directly crushes use, by Folium Sennae, Fructus Manglietiae fordianae, Herba Cistanches, Radix Glycyrrhizae, wheat
The component that winter, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Flos Sophorae, Herba Artemisiae etc. be slightly poisonous or active component is difficult to extract obtains extracting solution using water extraction or alcohol extraction to be made
With, retain the effective ingredient of each raw material to greatest extent, and mitigate toxic and side effects, making product be more suitable for old man, child and women makes
With.
The present embodiment additionally provides a kind of health food of prevention and treatment constipation, and the health food is prepared into above-mentioned
The Chinese medicine composition of the loosening bowel to relieve constipation for arriving and mixed grain rice are by 1:The ratio mixing of 4-10, and prepare.Obtained health care food
Product can effectively prevent and treat constipation, and have nourishing and health preserving, effect that QI invigorating is refreshed oneself.Above-mentioned mixed grain rice include greatly
The five class Foods such as rice, Semen setariae, beans, Semen Maydiss, potato class and some conventional food.
With reference to embodiments the feature and performance of the present invention are described in further detail.
Embodiment 1
Embodiment 1 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1800g Folium Sennae, 1300g Fructus Manglietiae fordianaes, 800g Radix Angelicae Sinensis, 800g Herba Cistanches, 800g parts
Radix Glycyrrhizae and 800g Mel；
Radix Angelicae Sinensis were crushed into 150 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1800g Folium Sennae and 9000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Folium Sennae and carries
Take liquid；800g Herba Cistanches and 6000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, is filtrated to get Herba Cistanches extracting solution；
1300g Fructus Manglietiae fordianaes and 8000g water are extracted 2 times at 80 DEG C, is decocted 2.5 hours every time, is filtrated to get Fructus Manglietiae fordianae extracting solution；Will
800g Radix Glycyrrhizaes are extracted 2 times at 70 DEG C with 4000g water, decoct 2 hours every time, are filtrated to get Radix Glycyrrhizae extract；Folium Sennae is carried
Take liquid, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract and merge and obtain extracting liquid mixture, and be concentrated to give extraction
Thing mastic.
By powder, extract mastic and Mel mix homogeneously, and it is prepared into ointment.
Embodiment 2
Embodiment 2 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1500g Folium Sennae, 1200g Fructus Manglietiae fordianaes, 750g Radix Angelicae Sinensis, 750g Herba Cistanches, 600g parts
Radix Glycyrrhizae and 750g Mel；
Radix Angelicae Sinensis were crushed into 150 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1500g Folium Sennae and 9000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Folium Sennae and carries
Take liquid；750g Herba Cistanches and 6000g water are extracted 2 times at 60 DEG C, is decocted 2.5 hours every time, be filtrated to get Herba Cistanches extraction
Liquid；1200g Fructus Manglietiae fordianaes and 7000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Fructus Manglietiae fordianae extracting solution；
600g Radix Glycyrrhizaes and 4000g water are extracted 2 times at 60 DEG C, is decocted 2.5 hours every time, is filtrated to get Radix Glycyrrhizae extract；By Senna fruit
Leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract merging are obtained extracting liquid mixture, and are concentrated to give
Extract mastic.
By powder, extract mastic and Mel mix homogeneously, and it is prepared into pill.
Embodiment 3
Embodiment 3 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1600g Folium Sennae, 1500g Fructus Manglietiae fordianaes, 900g Radix Angelicae Sinensis, 900g Herba Cistanches, 900g are sweet
Grass, 900g Mel, 800g Fructus Momordicaes.
Radix Angelicae Sinensis were crushed into 150 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1600g Folium Sennae and 12000g water are extracted 2 times at 70 DEG C, is decocted 1.5 hours every time, is filtrated to get Folium Sennae
Extracting solution；900g Herba Cistanches and 5000g water are extracted 2 times at 60 DEG C, is decocted 2 hours every time, be filtrated to get Herba Cistanches extraction
Liquid；80% ethanol of 800g Fructus Momordicaes and 2000g is extracted twice in hot reflux heating extraction device, 2 hours every time, extracted
Temperature 70 C, obtains Fructus Momordicae extracting solution；1500g Fructus Manglietiae fordianaes and 7500g water are extracted 2 times at 80 DEG C, 2 is decocted every time little
When, it is filtrated to get Fructus Manglietiae fordianae extracting solution；900g Radix Glycyrrhizaes and 5000g water are extracted 2 times at 80 DEG C, is decocted 1.5 hours every time, mistake
Filter obtains Radix Glycyrrhizae extract；Senna fruit leaf extract, Fructus Manglietiae fordianae extracting solution, Herba Cistanches extracting solution, Radix Glycyrrhizae extract, Fructus Momordicae are carried
Take liquid and obtain extracting liquid mixture, and be concentrated to give extract mastic.
By powder, extract mastic and Mel mix homogeneously, and prepare piece agent.
Embodiment 4
Embodiment 4 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1700g Folium Sennae, 1200g Fructus Manglietiae fordianaes, 600g Radix Angelicae Sinensis, 600g Herba Cistanches, 600g are sweet
Grass, 600g Mel, 400g Fructus Momordicaes, 200g Lagotis clarkei Hook. F (Lagotis brevituba Maxim.).
Radix Angelicae Sinensis were crushed into 200 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1700g Folium Sennae and 10000g water are extracted 2 times at 75 DEG C, is decocted 2 hours every time, is filtrated to get Folium Sennae and carries
Take liquid；600g Herba Cistanches and 6000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Herba Cistanches extracting solution；
70% ethanol of 400g Fructus Momordicaes and 800g is extracted twice in hot reflux heating extraction device, 1.5 hours every time, extract temperature
70 DEG C of degree, obtains Fructus Momordicae extracting solution；1200g Fructus Manglietiae fordianaes and 7000g water are extracted 2 times at 80 DEG C, are decocted 2 hours every time,
It is filtrated to get Fructus Manglietiae fordianae extracting solution；600g Radix Glycyrrhizaes and 4000g water are extracted 2 times at 80 DEG C, is decocted 1.5 hours every time, filtered
Obtain Radix Glycyrrhizae extract；200g Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) and 1000g water are extracted 2 times at 60 DEG C, is decocted 1 hour every time, is filtrated to get Lagotis clarkei Hook. F (Lagotis brevituba Maxim.)
Extracting solution；By Senna fruit leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract, Fructus Momordicae extracting solution, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.)
Extracting solution merging obtains extracting liquid mixture, and is concentrated to give extract mastic.
By powder, extract mastic and Mel mix homogeneously, drying, and it is prepared into capsule.
Embodiment 5
Embodiment 5 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1500g Folium Sennae, 1000g Fructus Manglietiae fordianaes, 600g Radix Angelicae Sinensis, 600g Herba Cistanches, 600g are sweet
Grass, 1000g Mel, 300g Fructus Momordicaes and 150g Herba Artemisiae.
Radix Angelicae Sinensis were crushed into 100 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1500g Folium Sennae and 12000g water are extracted 2 times at 80 DEG C, is decocted 1.5 hours every time, is filtrated to get Folium Sennae
Extracting solution；600g Herba Cistanches and 5000g water are extracted 2 times at 60 DEG C, is decocted 2 hours every time, be filtrated to get Herba Cistanches extraction
Liquid；70% ethanol of 300g Fructus Momordicaes and 1200g is extracted twice in hot reflux heating extraction device, 1.5 hours every time, is carried
Temperature 70 C is taken, Fructus Momordicae extracting solution is obtained；1000g Fructus Manglietiae fordianaes and 6000g water are extracted 2 times at 80 DEG C, 2 is decocted every time little
When, it is filtrated to get Fructus Manglietiae fordianae extracting solution；600g Radix Glycyrrhizaes and 4000g water are extracted 2 times at 60 DEG C, is decocted 2 hours every time, filtered
Obtain Radix Glycyrrhizae extract；150g Herba Artemisiae and 1500g water are extracted 2 times at 60 DEG C, is decocted 1 hour every time, is filtrated to get Herba Artemisiae
Extracting solution；By Senna fruit leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract, Fructus Momordicae extracting solution, Herba Artemisiae
Extracting solution simultaneously obtains extracting liquid mixture, and be concentrated to give extract mastic.
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent.
Embodiment 6
Embodiment 6 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material 1600g Folium Sennae, 1500g Fructus Manglietiae fordianaes, 700g Radix Angelicae Sinensis, 700g Herba Cistanches, 650g by weight sweet
Grass, 800g Mel, 250g Fructus Momordicaes and 180g Flos Sophoraes.
Radix Angelicae Sinensis were crushed into 200 mesh sieves, by the Radix Angelicae Sinensis mix homogeneously for sieving, powder was obtained；
1600g Folium Sennae and 8500g water are extracted 2 times at 60 DEG C, is decocted 2.5 hours every time, is filtrated to get Folium Sennae
Extracting solution；700g Herba Cistanches and 7000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, be filtrated to get Herba Cistanches extraction
Liquid；70% ethanol of 250g Fructus Momordicaes and 800g is extracted twice in hot reflux heating extraction device, 1.5 hours every time, is carried
Temperature 70 C is taken, Fructus Momordicae extracting solution is obtained；1500g Fructus Manglietiae fordianaes and 9000g water are extracted 2 times at 80 DEG C, 2 is decocted every time little
When, it is filtrated to get Fructus Manglietiae fordianae extracting solution；650g Radix Glycyrrhizaes and 5000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, filtered
Obtain Radix Glycyrrhizae extract；180g Flos Sophoraes and 1500g water are extracted 2 times at 60 DEG C, is decocted 1 hour every time, is filtrated to get Flos Sophorae
Extracting solution；By Senna fruit leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract, Fructus Momordicae extracting solution, Radix Ophiopogonis
Extracting solution, the conjunction of Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Herba Artemisiae extracting solution, Flos Sophorae extract simultaneously obtain extracting liquid mixture, and be concentrated to give extract
Mastic.
By powder, extract mastic and Mel mix homogeneously, and it is prepared into granule.
Embodiment 7
Embodiment 7 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1800g Folium Sennae, 1600g Fructus Manglietiae fordianaes, 1000g Radix Angelicae Sinensis, 1000g Herba Cistanches,
1000g Radix Glycyrrhizaes, 800g Mel, 400g Colla Corii Asini.
Radix Angelicae Sinensis, Colla Corii Asini are crushed respectively, and crosses 200 mesh sieves, the Colla Corii Asini mix homogeneously after the Radix Angelicae Sinensis after sieve, sieve is obtained
Powder.
1800g Folium Sennae and 9000g water are extracted 2 times at 65 DEG C, is decocted 2.5 hours every time, is filtrated to get Folium Sennae
Extracting solution；1000g Herba Cistanches and 7500g water are extracted 2 times at 75 DEG C, is decocted 1.5 hours every time, is filtrated to get Herba Cistanches and carries
Take liquid；1600g Fructus Manglietiae fordianaes and 8000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, be filtrated to get Fructus Manglietiae fordianae extraction
Liquid；1000g Radix Glycyrrhizaes and 5000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Radix Glycyrrhizae extract；General kind
Rush down leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract and merge and obtain extracting liquid mixture, and be concentrated to give
To extract mastic.
By powder, extract mastic and Mel mix homogeneously, drying, and prepare piece agent.
Embodiment 8
Embodiment 8 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1600g Folium Sennae, 1200g Fructus Manglietiae fordianaes, 800g Radix Angelicae Sinensis, 800g Herba Cistanches, 800g are sweet
Grass, 1000g Mel and 200g Semen Sesami Nigrums.
Radix Angelicae Sinensis and Semen Sesami Nigrum are crushed respectively, and crosses 200 mesh sieves, by the Semen Sesami Nigrum mix homogeneously after the Radix Angelicae Sinensis after sieve, sieve,
Obtain powder.
1600g Folium Sennae and 9500g water are extracted 2 times at 80 DEG C, is decocted 2.5 hours every time, is filtrated to get Folium Sennae
Extracting solution；800g Herba Cistanches and 8500g water are extracted 2 times at 65 DEG C, is decocted 2.5 hours every time, is filtrated to get Herba Cistanches and carries
Take liquid；1200g Fructus Manglietiae fordianaes and 8000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, be filtrated to get Fructus Manglietiae fordianae extraction
Liquid；800g Radix Glycyrrhizaes and 6000g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Radix Glycyrrhizae extract；By Senna fruit
Leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract merging are obtained extracting liquid mixture, and are concentrated to give
Extract mastic.
By powder, extract mastic and Mel mix homogeneously, and it is prepared into granule.
Embodiment 9
Embodiment 9 provides a kind of Chinese medicine composition of loosening bowel to relieve constipation, and its preparation method is as follows：
Prepare raw material by weight：1600g Folium Sennae, 1200g Fructus Manglietiae fordianaes, 800g Radix Angelicae Sinensis, 800g Herba Cistanches, 800g are sweet
Grass, 1000g Mel, 300g Fructus Momordicaes, 250g Radix Ophiopogonis, 250g Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 200g Colla Corii Asini, 200g Semen Sesami Nigrums.
Radix Angelicae Sinensis, Colla Corii Asini, Semen Sesami Nigrum are crushed respectively, and crosses 100 mesh sieves, after the Colla Corii Asini after the Radix Angelicae Sinensis after sieve, sieve, sieve
Semen Sesami Nigrum mix homogeneously, obtains powder.
1600g Folium Sennae and 11000g water are extracted 2 times at 70 DEG C, is decocted 2 hours every time, is filtrated to get Folium Sennae and carries
Take liquid；800g Herba Cistanches and 6500g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get Herba Cistanches extracting solution；
80% ethanol of 300g Fructus Momordicaes and 900g is extracted twice in hot reflux heating extraction device, 1.5 hours every time, extract temperature
60 DEG C of degree, obtains Fructus Momordicae extracting solution；1200g Fructus Manglietiae fordianaes and 6000g water are extracted 2 times at 80 DEG C, are decocted 2 hours every time,
It is filtrated to get Fructus Manglietiae fordianae extracting solution；800g Radix Glycyrrhizaes and 5000g water are extracted 2 times at 70 DEG C, is decocted 2.5 hours every time, filtered
Obtain Radix Glycyrrhizae extract；250 Radix Ophiopogonis and 1500g water are extracted 2 times at 80 DEG C, is decocted 2 hours every time, is filtrated to get and carries Radix Ophiopogonis
Take liquid；250g Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) and 2000g water are extracted 2 times at 80 DEG C, is decocted 1.5 hours every time, is filtrated to get Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution；Will
Senna fruit leaf extract, Herba Cistanches extracting solution, Fructus Manglietiae fordianae extracting solution, Radix Glycyrrhizae extract, Fructus Momordicae extracting solution, Radix Ophiopogonis extract, flood
Even extracting solution merges and obtains extracting liquid mixture, and is concentrated to give extract mastic.
By powder, extract mastic and Mel mix homogeneously, and prepare paste making agent.
Embodiment 10
Embodiment 10 provides a kind of health food of prevention and treatment constipation, and its preparation method is as follows：Embodiment 9 is made
The standby unguentum for obtaining and oatmeal in mass ratio 1:6 ratio mixing, and add water and make dough, cook.
Embodiment 11
Embodiment 11 provides a kind of health food of prevention and treatment constipation, and its preparation method is as follows：Embodiment 8 is made
The standby granule for obtaining and Oryza glutinosa in mass ratio 1:8 ratio mix homogeneously, cooks.
The effect of the present invention is described in further detail below by way of clinical trial.
First, pharmacology's toxicological test.
The unguentum prepared from embodiment 5 carries out toxicological test, and test shows：The product safety is nontoxic.
1.1 acute toxicity test in mice, male and female its mouse oral MTD value are all higher than 20g/kg.d, according to acute oral toxicity
Grade scale, the sample belong to nontoxic level.
1.2 60 days feeding trials：Unguentum prepared by embodiment 5 (is respectively equivalent to people with 750 and 1500mg/kg dosage
75 and 150 times of body recommended intake) feed rat 15 days, the ordinary circumstance of animal, body weight, food-intake, food under two dosage
Thing utilization rate, hematology, blood biochemical analysis, organ weights, dirty body when high dose group histopathological examination and matched group ratio
Significant difference is showed no relatively.
2nd, pharmacology test.
2.1 trial drug：The unguentum prepared from embodiment 5 is tested.
2.2. try out animal：From 20-24g rats, male and female half and half, by rat be randomly assigned into matched group and first group,
Second group, the 3rd group of three test groups, 10 per group, single cage is raised, and freely absorbs water and feedstuff.
2.3 test method：
2.3.1 defecation balance meassurement.After by mice fasting 12 hours, give feedstuff gavage to control group mice, to first
Mice gives the feedstuff that is mixed into unguentum in embodiment 5 and makes intake reach 0.1g unguentum/kg.d, gives to second group of mice group
It is mixed into the feedstuff of unguentum in embodiment 5 and makes intake reach 0.2g unguentum/kg.d, gives to the 3rd group of mice and be mixed into embodiment
The feedstuff of unguentum intake is made to reach 0.3g unguentum/kg.d in 5, argol number that every group of mice of observed and recorded is discharged, loose stool number
And the not animal of defecation, as shown in table 2.
2.3.2 intestinal propulsion speed trial.Forage feed is given 30 days by control group mice；First group of mice is given mixed
Enter the forage feed of unguentum in embodiment 1 30 days, and make intake reach 0.1g unguentum/kg.d；Second group of mice is given mixed
Enter the forage feed of unguentum in embodiment 5 30 days, and make intake reach 0.2g unguentum/kg.d；3rd group of mice is given mixed
Enter the forage feed of unguentum in embodiment 9 30 days, and make intake reach 0.3g unguentum/kg.d, four groups of Mouse Weights of record become
Change, as shown in table 1；Subsequently 5% mass was respectively given to matched group, first group, second group, the 3rd group of mice at the 31st day dense
The white carbon black aqueous solution gavage of degree, 30min after gavage put to death mice, and taking-up gastrointestinal of cutting open the belly immediately is laid on glass plate, measure
Charcoal end head end displacement and small intestinal total length (from pylorus to ileum) in the intestinal tube, before calculating intestinal propulsion percentage rate %=charcoals end
End and the distance/small intestinal total length of pylorus, as shown in table 3.
2.4 result
2.4.1 the change of each group the weight of animals during testing is shown in Table 1.
The impact (means standard deviation) of table 1 Chinese medicine composition to Mouse Weight (g)
From table 1, there was no significant difference between the weight of animals each group during test (P>0.05), each dosage group is little to testing
The body weight of Mus has no significantly impact.
2.4.2 impact of the Chinese medicine composition to mice defecation situation is shown in Table 2.
Impact (means standard deviation) of 2 Chinese medicine composition of table to mice defecation situation
From table 2, first group after test-meal, second group and the 3rd week mice defecation situation compare with matched group, difference has
Statistical significance (P ＜ 0.05), the rat defecation situation for taking the feedstuff for being mixed with Chinese medicine composition significantly take a turn for the better.
2.4.3 impact of the Chinese medicine composition to mouse small intestine ahead running is shown in Table 3.
Impact (means standard deviation) of 3 Chinese medicine composition of table to mouse small intestine advance distance (cm)
From table 3, first group after test-meal, second group and the 3rd week mouse small intestine advance distance compare with matched group, it is poor
Different statistically significant (P ＜ 0.05), takes the mouse small intestine wriggling situation for being mixed with Chinese medicine composition feedstuff with very big
Improve.
In sum, the Chinese medicine composition of the loosening bowel to relieve constipation of the embodiment of the present invention has promotion intestinal peristalsis promoting, improves intestinal
Effect of degree of wetting, can effectively prevent and treat constipation.The preparation method of the Chinese medicine composition of the loosening bowel to relieve constipation can be closed
Effective ingredient in the utilization raw material of reason, reduces the toxic and side effects of raw material.
Embodiments described above is a part of embodiment of the invention, rather than the embodiment of whole.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected enforcement of the present invention
Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of Chinese medicine composition of loosening bowel to relieve constipation, it is characterised in which is prepared from the following materials, and counts by weight,
The raw material includes：
2. the Chinese medicine composition of loosening bowel to relieve constipation according to claim 1, it is characterised in that count by weight, which includes：
3. the Chinese medicine composition of loosening bowel to relieve constipation according to claim 1, it is characterised in that count by weight, the original
Material also includes 6-12 part heat clearing away components, the heat clearing away component include Fructus Momordicae, Radix Ophiopogonis, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), Herba Artemisiae, in Flos Sophorae at least one
Kind.
4. the Chinese medicine composition of loosening bowel to relieve constipation according to claim 3, it is characterised in that count by weight, the original
Material includes：
5. the Chinese medicine composition of loosening bowel to relieve constipation according to claim 1, it is characterised in that count by weight, the original
Material also includes that 6-12 parts nourish component, and the nourishing component includes at least one in Colla Corii Asini, Semen Sesami Nigrum, Fructus Lycii.
6. the Chinese medicine composition of loosening bowel to relieve constipation according to claim 5, it is characterised in that count by weight, the original
Material includes：
7. a kind of preparation method of the Chinese medicine composition of loosening bowel to relieve constipation as claimed in claim 1, it is characterised in which includes：
Prepare raw material 15-20 part Folium Sennae, 10-16 part Fructus Manglietiae fordianaes, 6-12 part Radix Angelicae Sinensis, 6-12 part Herba Cistanches, 6- by weight
10 portions of Radix Glycyrrhizaes and 6-10 part Mel；
The Radix Angelicae Sinensis are crushed, powder is obtained；
The Folium Sennae is extracted using water extraction, Senna fruit leaf extract is obtained；The Fructus Manglietiae fordianae is extracted using water extraction, is obtained
To Fructus Manglietiae fordianae extracting solution；The Herba Cistanches are extracted using water extraction, Herba Cistanches extracting solution is obtained；The Radix Glycyrrhizae is used into water extraction
Method is extracted, and obtains Radix Glycyrrhizae extract；By the Senna fruit leaf extract, the Fructus Manglietiae fordianae extracting solution, the Herba Cistanches extracting solution and
The Radix Glycyrrhizae extract merging obtains extracting liquid mixture, and is concentrated to give extract mastic；
By the powder, the extract mastic and the Mel mix homogeneously, and prepare paste making agent, granule, pill, tablet
Or capsule.
8. the preparation method of the Chinese medicine composition of loosening bowel to relieve constipation according to claim 7, it is characterised in that by weight
When preparing the raw material, the raw material also includes 2-4 part Fructus Momordicaes, 1-2 parts Radix Ophiopogonis, 1-2 part Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), 1-2 part Flos Sophoraes, 1-2 parts
Herba Artemisiae；When the extract mastic is prepared, the Radix Ophiopogonis, the Lagotis clarkei Hook. F (Lagotis brevituba Maxim.), the Flos Sophorae are extracted using water extraction respectively, obtained
To Radix Ophiopogonis extract, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, Flos Sophorae extract；The Fructus Momordicae, the Herba Artemisiae are extracted using alcohol extracting method respectively, is obtained
To Fructus Momordicae extracting solution, Herba Artemisiae extracting solution；By the Radix Ophiopogonis extract, the Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) extracting solution, the Flos Sophorae extract, described
Fructus Momordicae extracting solution, the Herba Artemisiae extracting solution are mixed homogeneously with the extraction liquid mixture, and are concentrated to give the extract cream
Body.
9. the preparation method of the Chinese medicine composition of loosening bowel to relieve constipation according to claim 7, it is characterised in that by weight
When preparing the raw material, the raw material also includes 2-4 part Colla Corii Asini, 2-4 parts Semen Sesami Nigrum and 2-4 part Fructus Lycii；Preparing the powder
During material, the Colla Corii Asini, the Semen Sesami Nigrum, the Fructus Lycii are crushed, and mixed homogeneously with the Radix Angelicae Sinensis after crushing, institute is obtained
State powder.
10. it is a kind of prevention and treatment constipation health food, it is characterised in that the health food be will in claim 1-6 appoint
The Chinese medicine composition of the loosening bowel to relieve constipation described in presses 1 with mixed grain rice:The weight of 4-10 is than mixing, and prepares.
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| CN201611158806.9A Pending CN106606550A (en) | 2016-12-15 | 2016-12-15 | Traditional Chinese medicine composition capable of moistening intestines and relaxing bowels and preparation method thereof, and health food |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107865174A (en) * | 2017-12-24 | 2018-04-03 | 肇庆市高新区伟瑞生物科技有限公司 | A kind of herbal tea to relax bowel |
| CN109998068A (en) * | 2019-04-04 | 2019-07-12 | 北京紫云英保健品开发有限责任公司 | A kind of preparation process of relax bowel and defecation honey |
| CN112772812A (en) * | 2019-11-04 | 2021-05-11 | 晨光生物科技集团邯郸有限公司 | Composition for tonifying qi, moistening intestines and relaxing bowels and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857419A (en) * | 2005-04-30 | 2006-11-08 | 高春清 | Cathartic honey for treating constipation and its preparing method |
-
2016
- 2016-12-15 CN CN201611158806.9A patent/CN106606550A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857419A (en) * | 2005-04-30 | 2006-11-08 | 高春清 | Cathartic honey for treating constipation and its preparing method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107865174A (en) * | 2017-12-24 | 2018-04-03 | 肇庆市高新区伟瑞生物科技有限公司 | A kind of herbal tea to relax bowel |
| CN109998068A (en) * | 2019-04-04 | 2019-07-12 | 北京紫云英保健品开发有限责任公司 | A kind of preparation process of relax bowel and defecation honey |
| CN112772812A (en) * | 2019-11-04 | 2021-05-11 | 晨光生物科技集团邯郸有限公司 | Composition for tonifying qi, moistening intestines and relaxing bowels and preparation method thereof |
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Application publication date: 20170503 |