CN106604737B - 鼠尾草素组合物和其用途 - Google Patents

鼠尾草素组合物和其用途 Download PDF

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Publication number
CN106604737B
CN106604737B CN201580026976.9A CN201580026976A CN106604737B CN 106604737 B CN106604737 B CN 106604737B CN 201580026976 A CN201580026976 A CN 201580026976A CN 106604737 B CN106604737 B CN 106604737B
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carnosin
subject
administration
cerebral
composition
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Chinese (zh)
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CN106604737A (zh
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刘仁玉
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201580026976.9A 2014-03-21 2015-03-23 鼠尾草素组合物和其用途 Active CN106604737B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461968667P 2014-03-21 2014-03-21
US61/968,667 2014-03-21
PCT/US2015/021994 WO2015143429A2 (en) 2014-03-21 2015-03-23 Salvinorin compositions and uses thereof

Publications (2)

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CN106604737A CN106604737A (zh) 2017-04-26
CN106604737B true CN106604737B (zh) 2020-07-21

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CN201580026976.9A Active CN106604737B (zh) 2014-03-21 2015-03-23 鼠尾草素组合物和其用途

Country Status (4)

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EP (2) EP3685843A3 (enExample)
JP (2) JP2017508768A (enExample)
CN (1) CN106604737B (enExample)
WO (1) WO2015143429A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3685843A3 (en) 2014-03-21 2020-09-02 The Trustees of the University of Pennsylvania Uses of salvinorin a
CN110664799B (zh) * 2019-10-14 2020-06-19 河北医科大学第二医院 用于治疗脑缺血的药物组合物及其应用
CN118267384B (zh) * 2024-03-27 2024-12-20 徐州医科大学 κ阿片受体激动剂在制备预防和/或治疗颞叶癫痫药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102186503A (zh) * 2008-10-15 2011-09-14 埃里莫斯医药品有限公司 不溶于水或难溶于水的药物的稳定水性制剂
CN103313601A (zh) * 2010-06-29 2013-09-18 宾夕法尼亚大学理事会 salvinorin组合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531569B2 (en) * 2003-12-02 2009-05-12 Sanofi-Aventis Deutschland Gmbh Process for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives
AU2005222640A1 (en) 2004-03-12 2005-09-29 The Mclean Hospital Corporation Salvinorin derivatives and uses thereof
AT505086B1 (de) 2007-04-02 2009-06-15 Planta Naturstoffe Vertriebsge Pharmazeutisches mittel gegen juckreiz und juckreizbedingten schmerz
US11000505B2 (en) * 2010-06-29 2021-05-11 The Trustees Of The University Of Pennsylvania Salvinorin compositions and uses thereof
US8563470B2 (en) * 2010-12-13 2013-10-22 E I Du Pont De Nemours And Company Anthranilic diamide and cyclodextrin compositions for propagule coating
EP3685843A3 (en) 2014-03-21 2020-09-02 The Trustees of the University of Pennsylvania Uses of salvinorin a

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102186503A (zh) * 2008-10-15 2011-09-14 埃里莫斯医药品有限公司 不溶于水或难溶于水的药物的稳定水性制剂
CN103313601A (zh) * 2010-06-29 2013-09-18 宾夕法尼亚大学理事会 salvinorin组合物及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
紫珠属植物的化学成分及生物活性研究进展;王艳晶等;《中草药》;20080112;第39卷(第01期);133-138 *

Also Published As

Publication number Publication date
EP3685843A2 (en) 2020-07-29
WO2015143429A3 (en) 2015-12-10
JP2020045359A (ja) 2020-03-26
EP3119411A2 (en) 2017-01-25
WO2015143429A2 (en) 2015-09-24
EP3685843A3 (en) 2020-09-02
JP2017508768A (ja) 2017-03-30
CN106604737A (zh) 2017-04-26
EP3119411A4 (en) 2018-02-28
EP3119411B1 (en) 2019-11-27

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