CN106581780B - 一种润滑剂及其制备方法和应用 - Google Patents
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Abstract
本发明涉及一种润滑剂及其制备方法和应用。该润滑剂包括具有以下重量百分比的组分:增稠剂0.1‑1.0%、润滑剂0.1‑1.0%、保湿剂3.0‑10.0%、pH值调节剂0.1‑2.0%、防腐剂0.3‑2.0%,余量为无菌水;本发明润滑剂配方中的各个成分在特定的含量作用下,互相协同作用,具有很强的保湿滋润作用,性质温和,对人体无不良反应,同时还具有抗菌作用,对于妇产科窥视器械及阴道都具有极佳的润滑效果。
Description
技术领域
本发明涉及妇科润滑剂领域,具体涉及一种润滑剂及其制备方法和应用。
背景技术
我国人口众多,意味着需要接受妇科常规检查的成年妇女基数庞大,在现有的常规妇科检查时,如果使用窥视医疗器具,所用的润滑剂一般为凡士林、液体石蜡或硅油等,这些润滑剂都不理想,而接受常规妇科检查的女性,往往心情紧张不安,阴道容易干涩,没有适合润滑剂的辅助,会给身心带来不适;此外,围绝经期后的妇女,由于雌激素的下降,阴道壁干涩易裂,哺乳期的妇女,雌孕激素的变化导致阴道壁变薄,心情抑郁身体疲劳时会导致阴道干涩,上述这类人群,性生活时都需要安全有效的润滑剂的帮助;但是,目前市售的妇科用润滑剂均没有安全保障,并且多次使用,往往造成人为感染,给成年妇女带来极大身心烦恼和损害。
发明内容
本发明的一个目的是提供一种润滑剂,该润滑剂呈水溶性,无毒无害,无色无味,易于清洗,并且一次性使用,不易污染。
本发明的另一个目的是提供上述润滑剂的制备方法及应用。
本发明解决上述技术问题的技术方案如下:提供一种润滑剂,包括具有以下重量百分比的组分:
卡波树脂0.2%、银耳多糖0.7%、丙三醇1.0%、丁二醇2.0%、甜菜碱1.0%、精氨酸0.1%,sensiva SC10 0.3%,以及无菌水94.7%;senviva SC10由辛甘醇和乙基己基甘油以质量比7:3复配而成;
上述润滑剂的制备方法为:
(1)预先用80℃无菌水浸泡分散卡波树脂4小时,待卡波树脂充分溶胀备用;
(2)开启搅拌设备,于60℃无菌水中加入银耳多糖搅拌至完全溶解;
(3)将步骤(1)制得的溶胀后的卡波树脂加入步骤(2)的搅拌桶中搅拌混合均匀;
(4)再向步骤(3)制得的物质中分别加入丙三醇、丁二醇和甜菜碱,每种原料加入后,搅拌20分钟后加入下一种原料;再加入精氨酸调节溶液的pH值至4.5-5.0,最后加入防腐剂,搅拌1.5-2.0小时,离心,制得;
(5)将上述制得的润滑剂罐装入5-10ml聚乙烯软瓶中,封口辐照灭菌,包装后置阴凉通风处保存;
上述人体润滑剂主要用在妇产科窥视器械润滑及外阴粘膜的润滑中;
上述润滑剂在润滑时的使用方法为:一次性使用,妇产科检查操作时折断瓶颈,挤压出润滑剂至妇科窥视医疗器械前端即可使用,剩余部分废弃。
本发明的润滑剂可以在妇产科窥视检查及各种原因导致的阴道干涩的情况下使用,该润滑剂的配方采用具有润滑滋润作用的原料制成,对正常阴道菌群和酸碱度无影响,能够最大程度上达到润滑和舒缓的效果,并且无色无味,无毒无害,对人体无不良反应,制剂配方为水溶性,易于清洗。
该润滑剂在洁净后封装于聚乙烯软瓶中,臭氧、高温或辐照情况下消毒灭菌,采用一次性封闭包装,可在妇科窥视医疗器械润滑中使用,并且是一次性使用,妇产科检查操作时,折断瓶颈,挤压出润滑剂至妇科窥视医疗器械前端即可,剩余部分废弃;在日常性生活使用时,折断瓶颈,挤压出润滑剂至女性外阴口或男性生殖器前端即可,剩余部分废弃。
本发明润滑剂配方中的各个成分在特定的含量作用下,互相协同作用,具有很强的保湿滋润作用,性质温和,对人体无不良反应,同时还具有抗菌作用,对于妇产科窥视器械及阴道都具有极佳的润滑效果。
本发明的润滑剂选用银耳多糖、蓝丝美肤剂、酸豆籽多糖和皱波角叉菜中的一种或多种,优选银耳多糖,银耳多糖的保湿效果极好,其保湿作用原理是通过无数个的末端羟基与水分子结合形成氢键,从而结合大量的水,在空间形成一个分子海绵状的结构,进而具有极强的吸水性。
本发明的增稠剂选用卡波树脂、瓜尔胶、黄原胶、聚乙烯吡咯烷酮和聚丙烯酰胺中的一种或多种,优选卡波树脂,卡波树脂是含有聚烯基聚醚交联的丙烯酸聚合物,卡波分子中的羧基基团经碱中和离子化后,负电荷相互排斥,使分子链弥散伸展,大幅膨胀,少量卡波即能形成透明凝胶;卡波凝胶易于涂抹,肤感清透,但成膜性强,会造成皮肤的紧绷感;银耳多糖不容易随湿度的变化而收缩,高爽滑度,易于涂抹且不紧绷;银耳多糖和卡波树脂质量比在2:1-8:1可以复配出热稳定性好、爽滑度高、不紧绷、涂抹后不发热的凝胶。
本发明的防腐剂为senviva SC10、Spectrastat PHL、葡萄柚提取物和PA40中的一种或多种,优选senviva SC10,senviva SC10由辛甘醇和乙基己基甘油以质量比7:3复配而成;SC 10融合了乙基己基甘油的良好肤感和除臭特性以及辛甘醇的保湿、抗菌性能,作为复合原料性质温和无刺激,水溶性好;该防腐剂优选与银耳多糖和卡波树脂配合使用,从而得到润滑效果极佳且对人体无害的润滑剂。
具体实施方式
以下对本发明的原理和特征进行描述,所举实例只用于解释本发明,并非用于限定本发明的范围。
实施例1:
润滑剂,包括含有以下重量百分比的组分:
卡波树脂0.2%、银耳多糖0.7%、丙三醇1.0%、丁二醇2.0%、甜菜碱1.0%、精氨酸0.1%,sensiva SC10 0.3%,以及无菌水94.7%;senviva SC10由辛甘醇和乙基己基甘油以质量比7:3复配而成。
上述润滑剂的制备方法为:
(1)预先用80℃无菌水浸泡分散卡波树脂4小时,待卡波树脂充分溶胀备用;
(2)开启搅拌设备,于60℃无菌水中加入银耳多糖搅拌至完全溶解;
(3)将步骤(1)制得的溶胀后的卡波树脂加入步骤(2)的搅拌桶中搅拌混合均匀;
(4)再向步骤(3)制得的物质中分别加入丙三醇、丁二醇和甜菜碱,每种原料加入后,搅拌20分钟后加入下一种原料;再加入精氨酸调节溶液的pH值至4.5-5.0,最后加入防腐剂,搅拌1.5-2.0小时,离心,制得。
(5)将上述制得的润滑剂罐装入5-10ml聚乙烯软瓶中,封口辐照灭菌,包装后置阴凉通风处保存。
上述人体润滑剂主要用在妇产科窥视器械润滑及外阴粘膜的润滑中。
上述润滑剂在润滑时的使用方法为:一次性使用,妇产科检查操作时折断瓶颈,挤压出润滑剂至妇科窥视医疗器械前端即可使用,剩余部分废弃;在日常性生活使用时,折断瓶颈,挤压出润滑剂至女性外阴口或男性生殖器前端即可,剩余部分弃去。
试验例
本发明实施例1制得的用于人体的润滑剂的感官和理化指标为:
无色无味、透明粘滑,pH值为4.0-5.0;
微生物指标:无菌;
润滑效果:介于0.7-0.15之间;其中,较常见的物质的润滑性如下,空气0.5、清水0.35、柴油0.07、泥浆0.2-0.35;可见,本发明的润滑剂的润滑效果极佳。
A:随机选取常规妇科检查客户50例,知情同意后,体验本发明实施例2制得的润滑剂涂抹至窥阴医疗器械前端后的润滑效果,结果是:
反馈润滑舒适,无不良反应。
B:选取由于各种原因导致房事干涩疼痛的成年妇女30例,体验本发明实施例1制得的润滑剂在性生活时改善干涩疼痛的润滑效果,结果是:
反馈润滑效果明显,愉悦舒适,显著改善疼痛干涩,无疼痒刺激,无感染。以上所述仅为本发明的较佳实施例,并不用以限制本发明,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (1)
1.一种润滑剂,其特征是,包括具有以下重量百分比的组分:
卡波树脂0.2%、银耳多糖0.7%、丙三醇1.0%、丁二醇2.0%、甜菜碱1.0%、精氨酸0.1%,sensiva SC 10 0.3%,以及无菌水94.7%;senviva SC 10由辛甘醇和乙基己基甘油以质量比7:3复配而成;
上述润滑剂的制备方法为:
(1)预先用80℃无菌水浸泡分散卡波树脂4小时,待卡波树脂充分溶胀备用;
(2)开启搅拌设备,于60℃无菌水中加入银耳多糖搅拌至完全溶解;
(3)将步骤(1)制得的溶胀后的卡波树脂加入步骤(2)的搅拌桶中搅拌混合均匀;
(4)再向步骤(3)制得的物质中分别加入丙三醇、丁二醇和甜菜碱,每种原料加入后,搅拌20分钟后加入下一种原料;再加入精氨酸调节溶液的pH值至4.5-5.0,最后加入防腐剂,搅拌1.5-2.0小时,离心,制得;
(5)将上述制得的润滑剂罐装入5-10ml聚乙烯软瓶中,封口辐照灭菌,包装后置阴凉通风处保存;
上述- 润滑剂主要用在妇产科窥视器械润滑及外阴粘膜的润滑中;
上述润滑剂在润滑时的使用方法为:一次性使用,妇产科检查操作时折断瓶颈,挤压出润滑剂至妇科窥视医疗器械前端即可使用,剩余部分废弃。
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