CN106581352A - Blood pressure lowering medicine and production method thereof - Google Patents
Blood pressure lowering medicine and production method thereof Download PDFInfo
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- CN106581352A CN106581352A CN201510662282.6A CN201510662282A CN106581352A CN 106581352 A CN106581352 A CN 106581352A CN 201510662282 A CN201510662282 A CN 201510662282A CN 106581352 A CN106581352 A CN 106581352A
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Abstract
The invention discloses a blood pressure lowering medicine and a production method thereof, wherein the blood pressure lowering medicine is mainly prepared from concha cypraeae violacae, allium victorialis l, dendrobium, longan pulp, dandelion, arthraxon hispidus(thunb.)makino, geum japonicum thunb. var. chinense f. bolle, centaurium pulchellum (swartz) druce var. altaicum moench, ballooflower rhizome, gomuti sugarpalm fruit, oxalis corymbosa dc, tylophora mollissima, cortex moutan, leonurus artemisia, angelica sinensis, codonopsis pilosula, eucommia ulmoides oliver and mulberry leaf. The blood pressure lowering medicine of the present invention has the blood pressure lowering effect, can be used for high blood pressure treatment, and has characteristics of significant treatment effect, short treatment cycle, safety, and no side effect.
Description
Technical field
The present invention relates to a kind of medicine of blood pressure lowering and preparation method thereof, belongs to the field of medicine technology.
Technical background
Hypertension is the arch-criminal of cardiovascular and cerebrovascular disease, be the dead root of kidney and interior organ failure because, it is high with sickness rate, the characteristics of control rate is low.It is the great public health problem in global range and cardiovascular and cerebrovascular disease has been substituted infectious disease and has become the number one killer of human health.According to statistics, up to 600,000,000, China's resident's nutrition in 2004 shows whole world Hypertension number with Health Situation survey result, and China 18 years old and above Hypertension among Residents in Urban sickness rate are 18.8%, estimates national number of patients more than 1.6 hundred million, it is contemplated that 2025 will be up to 400,000,000.
For above-mentioned disease, although have much currently used for the medicine for the treatment of blood circulation promoting and blood stasis dispelling, but most drug is slow just for drug effect, and treatment cycle is long.
The content of the invention
It is an object of the present invention to provide a kind of medicine of blood pressure lowering and preparation method thereof.The medicine has the effect for reducing blood pressure, and can be used to treat hypertension；Evident in efficacy, treatment cycle is short, has no side effect safely.
To solve above-mentioned technical problem, the present invention employs the following technical solutions realization：A kind of medicine of blood pressure lowering, calculate by weight, be mainly made by Concha Erosariae seu Cypraeae 20-30 parts, Bulbus Allii Victorialis 10-15 parts, Herba Dendrobii 10-20 parts, Arillus Longan 20-30 parts, Herba Taraxaci 20-30 parts, Herba Arthraxonis Hispidi 25-35 parts, Herba Gei 35-45 parts, Herba centaurll altaici 25-35 parts, Rhizoma platycodi 30-40 parts, Fructus arengae pinnatae's 45-55 parts, red colored Vat slurries grass 20-30 parts, Radix Tylophorae mollissimae 25-35 parts, Cortex Moutan 5-15 parts, Herba Leonuri 10-20 parts, Radix Angelicae Sinensis 10-20 parts, Radix Codonopsis 10-20 parts, Cortex Eucommiae 15-25 part and Folium Mori 25-35 parts.
In the medicine of aforesaid blood pressure lowering, calculate by weight, be mainly made by 30 parts of 25 parts of Concha Erosariae seu Cypraeae, 12 parts of Bulbus Allii Victorialis, 15 parts of Herba Dendrobii, 25 parts of Arillus Longan, 25 parts of Herba Taraxaci, 30 parts of Herba Arthraxonis Hispidi, 40 parts of Herba Gei, 30 parts of Herba centaurll altaici, 35 parts of Rhizoma platycodi, 50 parts of Fructus arengae pinnatae, red colored 25 parts of Vat slurries grass, 30 parts of Radix Tylophorae mollissimae, 10 parts of Cortex Moutan, 15 parts of Herba Leonuri, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Codonopsis, 20 parts of the Cortex Eucommiae and Folium Mori.
A kind of manufacture method of the medicine of aforesaid blood pressure lowering, takes said medicine, can add adjuvant, it is also possible to be not added with adjuvant, makes oral formulations.
In the manufacture method of the medicine of aforesaid blood pressure lowering, the oral formulations are granule, capsule, tablet, pill, powder or cream.
In the manufacture method of the medicine of aforesaid blood pressure lowering, the granule so makes：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, and relative density is the extractum of 1.15-1.20, extractum and the starch and 20% dextrine powder mixing granulation of extractum amount 20% when being condensed into 50-60 DEG C, is dried, and is obtained final product.
In the manufacture method of the medicine of aforesaid blood pressure lowering, the manufacture method of the capsule is：Take said medicine, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filtrate recycling ethanol and when being condensed into 50-60 DEG C relative density for 1.20-1.25 extractum, the starch and 0.7% magnesium stearate and extractum for separately taking extractum amount 30% is mixed, with 60% alcohol granulation, dry, pulverize, filling capsule, obtains final product.
In the manufacture method of the medicine of aforesaid blood pressure lowering, the manufacture method of the tablet is：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, and relative density is the extractum of 1.15-1.20 when being condensed into 50-60 DEG C, and extractum is mixed with the starch of above-mentioned mixed powder and extractum amount 20%, and tabletting, film coating is obtained final product.
Compared with prior art, medicine of the present invention is mainly made by Concha Erosariae seu Cypraeae, Bulbus Allii Victorialis, Herba Dendrobii, Arillus Longan, Herba Taraxaci, Herba Arthraxonis Hispidi, Herba Gei, Herba centaurll altaici, Rhizoma platycodi, Fructus arengae pinnatae, Hong Hua Vat slurry grass, Radix Tylophorae mollissimae, Cortex Moutan, Herba Leonuri, Radix Angelicae Sinensis, the Radix Codonopsis 1, Cortex Eucommiae and Folium Mori, each raw material has good synergism in prescription, play altogether with the effect for reducing blood pressure, can be used to treat hypertension；Evident in efficacy, treatment cycle is short, has no side effect safely.
Treatment example：
Imperial ××, man, 63 years old, Jing Qiandongnan Prefecture of Guizhou Province the People's Hospital checked blood fat, and slight Hypertension ate as described in Example 1 product of the present invention after 2 months, and blood pressure, blood fat recovers normal.
Shen ××, man, 45 years old, high blood glucose in recent years.Start invented food, sooner or later each 1.5g, after eating January, blood glucose is normal.
Invention is further described with reference to embodiment, but is not intended as the foundation limited the present invention.
Specific embodiment
Embodiment 1.
Formula：Concha Erosariae seu Cypraeae 25g, Bulbus Allii Victorialis 12g, Herba Dendrobii 15g, Arillus Longan 25g, Herba Taraxaci 25g, Herba Arthraxonis Hispidi 30g, Herba Gei 40g, Herba centaurll altaici 30g, Rhizoma platycodi 35g, Fructus arengae pinnatae 50g, Hong Hua Vat slurry grass 25g, Radix Tylophorae mollissimae 30g, Cortex Moutan 10g, Herba Leonuri 15g, Radix Angelicae Sinensis 15g, Radix Codonopsis 15g, Cortex Eucommiae 20g and Folium Mori 30g.
Technique：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, and relative density is the extractum of 1.15-1.20, extractum and the starch and 20% dextrine powder mixing granulation of extractum amount 20% when being condensed into 50-60 DEG C, is dried, and obtains final product granule.
Specification：0.5g/ grains.
Usage and dosage：Every time 2-3 grains, daily 2-3 time.
Embodiment 2.
Formula：Concha Erosariae seu Cypraeae 20g, Bulbus Allii Victorialis 10g, Herba Dendrobii 10g, Arillus Longan 20g, Herba Taraxaci 20g, Herba Arthraxonis Hispidi 25g, Herba Gei 35g, Herba centaurll altaici 25g, Rhizoma platycodi 30g, Fructus arengae pinnatae 45g, Hong Hua Vat slurry grass 20g, Radix Tylophorae mollissimae 25g, Cortex Moutan 5g, Herba Leonuri 10g, Radix Angelicae Sinensis 10g, Radix Codonopsis 10g, Cortex Eucommiae 15g and Folium Mori 25g.
Technique：Take said medicine, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filtrate recycling ethanol and when being condensed into 50-60 DEG C relative density for 1.20-1.25 extractum, the starch and 0.7% magnesium stearate and extractum for separately taking extractum amount 30% is mixed, with 60% alcohol granulation, dry, pulverize, filling capsule, obtains final product capsule.
Specification：0.5g/ grains.
Usage and dosage：Every time 2-3 grains, daily 2-3 time.
Embodiment 3.
Formula：Concha Erosariae seu Cypraeae 30g, Bulbus Allii Victorialis 15g, Herba Dendrobii 20g, Arillus Longan 30g, Herba Taraxaci 30g, Herba Arthraxonis Hispidi 35g, Herba Gei 45g, Herba centaurll altaici 35g, Rhizoma platycodi 40g, Fructus arengae pinnatae 55g, Hong Hua Vat slurry grass 30g, Radix Tylophorae mollissimae 35g, Cortex Moutan 15g, Herba Leonuri 20g, Radix Angelicae Sinensis 20g, Radix Codonopsis 20g, Cortex Eucommiae 25g and Folium Mori 35g.
Technique：Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, and relative density is the extractum of 1.15-1.20, extractum and the starch and 20% dextrine powder mixing granulation of extractum amount 20% when being condensed into 50-60 DEG C, is dried, and obtains final product granule.
Specification：0.5g/ grains.
Usage and dosage：Every time 2-3 grains, daily 2-3 time.
Claims (7)
1. a kind of medicine of blood pressure lowering, it is characterised in that：Calculate by weight, mainly by Concha Erosariae seu Cypraeae 20-30 parts, Bulbus Allii Victorialis 10-15 parts,
Herba Dendrobii 10-20 parts, Arillus Longan 20-30 parts, Herba Taraxaci 20-30 parts, Herba Arthraxonis Hispidi 25-35 parts, Herba Gei 35-45 parts,
Herba centaurll altaici 25-35 parts, Rhizoma platycodi 30-40 parts, Fructus arengae pinnatae's 45-55 parts, Hong Hua Vat slurry grass 20-30 parts, Radix Tylophorae mollissimae 25-35
Part, Cortex Moutan 5-15 parts, Herba Leonuri 10-20 parts, Radix Angelicae Sinensis 10-20 parts, Radix Codonopsis 10-20 parts, Cortex Eucommiae 15-25 part and Folium Mori
25-35 parts are made.
2. the medicine of blood pressure lowering as claimed in claim 1, it is characterised in that：Calculate by weight, mainly by 25 parts of Concha Erosariae seu Cypraeae, For-carrying
12 parts of Herba Alii fistulosi, 15 parts of Herba Dendrobii, 25 parts of Arillus Longan, 25 parts of Herba Taraxaci, 30 parts of Herba Arthraxonis Hispidi, 40 parts of Herba Gei, Herba centaurll altaici 30
Part, 35 parts of Rhizoma platycodi, 50 parts of Fructus arengae pinnatae, 25 parts of Hong Hua Vat slurries grass, 30 parts of Radix Tylophorae mollissimae, 10 parts of Cortex Moutan, Herba Leonuri
30 parts of 15 parts, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Codonopsis, 20 parts of the Cortex Eucommiae and Folium Mori are made.
3. a kind of manufacture method of the medicine of blood pressure lowering as claimed in claim 1 or 2, it is characterised in that：Said medicine is taken, can be with
Plus adjuvant, it is also possible to adjuvant is not added with, oral formulations are made.
4. the manufacture method of the medicine of blood pressure lowering as claimed in claim 3, it is characterised in that：The oral formulations are granule, glue
Wafer, tablet, pill, powder or cream.
5. the manufacture method of the medicine of blood pressure lowering as claimed in claim 4, it is characterised in that：The granule so makes：Take
Medicine is stated, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and merges decoction liquor, relative density when being condensed into 50-60 DEG C
For the extractum of 1.15-1.20, extractum and the starch and 20% dextrine powder mixing granulation of extractum amount 20%, it is dried, obtains final product.
6. the manufacture method of the medicine of blood pressure lowering as claimed in claim 4, it is characterised in that：The manufacture method of the capsule is：
Said medicine is taken, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filtrate recycling ethanol
And relative density is the extractum of 1.20-1.25 when being condensed into 50-60 DEG C, separately takes the starch of extractum amount 30% and 0.7% stearic acid
Magnesium is mixed with extractum, with 60% alcohol granulation, be dry, pulverize, and fills capsule, is obtained final product.
7. the manufacture method of the medicine of blood pressure lowering as claimed in claim 4, it is characterised in that：The manufacture method of the tablet is：Take
Said medicine, plus 10 times amount decoctings boil 3 times, each 1.5h, filter, merge decoction liquor, be condensed into relatively close when 50-60 DEG C
The extractum for 1.15-1.20 is spent, extractum is mixed with the starch of above-mentioned mixed powder and extractum amount 20%, tabletting, film coating, i.e.,
.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510662282.6A CN106581352A (en) | 2015-10-14 | 2015-10-14 | Blood pressure lowering medicine and production method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510662282.6A CN106581352A (en) | 2015-10-14 | 2015-10-14 | Blood pressure lowering medicine and production method thereof |
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| CN106581352A true CN106581352A (en) | 2017-04-26 |
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| CN201510662282.6A Pending CN106581352A (en) | 2015-10-14 | 2015-10-14 | Blood pressure lowering medicine and production method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108541800A (en) * | 2018-05-08 | 2018-09-18 | 广西中医药大学 | A kind of novel pressed candy and preparation method thereof adjusting blood pressure |
| CN109730223A (en) * | 2019-03-05 | 2019-05-10 | 延边大学 | A kind of cold green onion beverage and the preparation method and application thereof |
-
2015
- 2015-10-14 CN CN201510662282.6A patent/CN106581352A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108541800A (en) * | 2018-05-08 | 2018-09-18 | 广西中医药大学 | A kind of novel pressed candy and preparation method thereof adjusting blood pressure |
| CN109730223A (en) * | 2019-03-05 | 2019-05-10 | 延边大学 | A kind of cold green onion beverage and the preparation method and application thereof |
| CN109730223B (en) * | 2019-03-05 | 2022-03-01 | 延边大学 | Cold onion beverage and preparation method and application thereof |
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Application publication date: 20170426 |