CN106580825B - Natural full-herbal foam toothpaste - Google Patents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/553—Phospholipids, e.g. lecithin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention provides natural full-herbal foam toothpaste which is prepared from the following raw materials: dendrobe extract, honeysuckle extract, moutan bark extract, amomum fruit extract, poria cocos extract, mint extract, clove extract, purple daisy extract, sodium phytate and amino acid. The '0' additive formula of the natural full-herbal toothpaste provided by the invention does not contain additives such as preservatives, abrasives, adhesive binders, alcohol and the like, the traditional Chinese medicine extract is directly absorbed by the spleen and the stomach through oral mucosa, has the functions of sterilization, bacteriostasis and analgesia, can refresh breath, relieve oral ulcer, maintain gum, effectively eliminate and prevent redness and swelling and bleeding of gum, brighten and whiten teeth, can be used by children and adults, and is safe and free of side effects.
Description
Technical Field
The invention relates to the technical field of toothpaste, in particular to natural full-herbal foam toothpaste.
Background
The oral cavity has a more complex microbial environment, 90% of adults have oral cavity problems of different degrees, and professional medical statistical data finds that the oral cavity problems such as oral ulcer, tooth open swelling and pain, bleeding, atrophy and the like are rapidly spreading along with the change of eating habits (numbness, spiciness and scalding) and the increase of working pressure. These oral "small problems", while not sufficient to go to hospitals, greatly confound people's mood, thereby creating a consumer demand for oral problems. Meanwhile, periodontal supporting tissues in the oral cavity are locally stimulated, such as dental calculus, food impaction, poor restoration bodies and the like, long-term mechanical stimulation, irregular dentition and incorrect tooth brushing method cause excessive load of part of teeth occlusal force, and gingivitis, periodontitis, alveolar abscess and other common oral diseases are caused by chemicals, burns, vitamin C deficiency, oral bacterial growth and the like. The toothpaste is a common cleaning product in daily life, and the quality requirement of the toothpaste is gradually improved along with the improvement of the living standard of people. Performance aspects generally require that toothpaste be capable of removing pellicle and plaque from the tooth surface without damaging the enamel and dentin; has good function of cleaning the oral cavity and the periphery thereof; no toxicity and no stimulation to oral mucosa; has comfortable fragrance and taste, and has cool and fresh feeling after use. Generally, effective medicines are added into toothpaste to prevent and treat various oral diseases caused by bacteria or viruses. Antibiotics can effectively resist bacteria, but have large side effects. The mainstream in the market is also traditional Chinese medicine toothpaste, but basically, several functional traditional Chinese medicine extracts are added on the basis of a toothpaste matrix, however, the toothpaste matrix comprises chemical additives such as preservatives, abrasive agents, adhesive binders, alcohol and the like, and the toothpaste matrix is a chemical substance and can have adverse effects on the oral cavity after long-term use; in addition, some added traditional Chinese medicines are complex and various in types, so that uncertain risks to the sterilization and bacteriostasis effects of the traditional Chinese medicines are caused, and the cost of the traditional Chinese medicines is increased. Therefore, for the reasons mentioned above, it is important to provide a herbal toothpaste with simple ingredients, safety and reliability, and "0" addition.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides natural full-herbal foam toothpaste.
In order to achieve the purpose, the invention is realized by the following technical scheme:
a natural full herbal foam toothpaste, which consists of the following raw materials: dendrobe extract, honeysuckle extract, moutan bark extract, amomum fruit extract, poria cocos extract, mint extract, clove extract, purple daisy extract, sodium phytate and amino acid.
Preferably, the weight parts of the raw materials are as follows: 10-15 parts of dendrobium extract, 10-15 parts of honeysuckle extract, 10-15 parts of moutan bark extract, 7-12 parts of fructus amomi extract, 15-20 parts of poria cocos extract, 10-15 parts of mint extract, 7-12 parts of clove extract, 15-20 parts of purple daisy extract, 2-5 parts of sodium phytate and 1-3 parts of amino acid.
Preferably, the weight parts of the raw materials are as follows: 13 parts of dendrobium extract, 15 parts of honeysuckle extract, 12 parts of moutan bark extract, 10 parts of fructus amomi extract, 15 parts of poria cocos extract, 12 parts of mint extract, 10 parts of clove extract, 17 parts of purple daisy extract, 4 parts of sodium phytate and 2 parts of amino acid.
Preferably, the preparation method of the dendrobium extract comprises the following steps: pulverizing herba Dendrobii, soaking in 4-6 times of water for 30min, decocting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the honeysuckle extract comprises the following steps: extracting flos Lonicerae with 4-6 times of 70-80% ethanol under reflux for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the moutan bark extract comprises the following steps: pulverizing cortex moutan, adding 1-2 times of 65-75% ethanol, and performing CO treatment2Performing supercritical extraction at the extraction pressure of 20-40MPa for 1-3h and the temperature of 40-50 ℃;
the preparation method of the fructus amomi extract comprises the following steps: pulverizing fructus Amomi, placing in ultrasonic extraction tank, adding 4-6 times of 70-80% ethanol, soaking for 30min, heating to 35-40 deg.C, performing ultrasonic treatment for 0.5-1h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the tuckahoe extract comprises the following steps: pulverizing Poria, soaking in 4-6 times of water for 30min, decocting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the mint extract comprises the following steps: pulverizing herba Menthae, adding 6-8 times of 70-80% ethanol, cold soaking for 20-25 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the clove extract comprises the following steps: adding 4-6 times of 70-80% ethanol into flos Caryophylli, heating, reflux extracting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the purple daisy extract comprises the following steps: adding 70-80% ethanol 4-6 times the amount of Echinacea purpurea, reflux extracting under heating for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature.
Preferably, in the preparation method of the fructus amomi extract, the ultrasonic power is 550-650W.
The effects of the raw materials of the invention are as follows:
and (3) dendrobium extract: it has effects in nourishing stomach yin, clearing away stomach heat, and treating gingival swelling and pain, and aphtha.
And (3) honeysuckle extract: can be used for relieving gingival swelling and pain, sore throat, and oral ulcer.
Moutan bark extract: paeonol has analgesic and antipyretic effects, and can relieve gingival swelling and pain and oral ulcer.
And (3) fructus amomi extract: has effects in activating qi-flowing, flavoring, regulating stomach function, and activating spleen.
And (3) poria cocos extract: it has effects in enhancing immunity, promoting digestion, protecting liver, and inhibiting ulcer.
And (3) mint extract: has refreshing fragrance, and can be used for relieving inflammation, relieving pain, and treating sore throat and toothache.
Clove extract: has special fragrance, and can warm middle warmer and dispel cold, and can be used for treating wind-cooling toothache, gingival atrophy and halitosis.
Purple daisy extract: can reduce inflammation and resist bacteria and viruses.
Sodium phytate: the pure natural green organic extract has the functions of whitening teeth and cleaning and removing dirt.
Amino acids: the important nutrients of human body provide material basis for normal metabolism and life maintenance.
The invention has the beneficial effects that: the '0' additive formula of the natural full-herbal toothpaste provided by the invention does not contain additives such as preservatives, abrasives, adhesive binders, alcohol and the like, the traditional Chinese medicine extract is directly absorbed by the spleen and the stomach through oral mucosa, has the functions of sterilization, bacteriostasis and analgesia, can refresh breath, relieve oral ulcer, maintain gum, effectively eliminate and prevent redness and swelling and bleeding of gum, brighten and whiten teeth, can be used by children and adults, and is safe and free of side effects.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a natural full herbal foam toothpaste, which consists of the following raw materials: dendrobe extract, honeysuckle extract, moutan bark extract, amomum fruit extract, poria cocos extract, mint extract, clove extract, purple daisy extract, sodium phytate and amino acid.
The preparation method of the natural full-herbal foam toothpaste comprises the following steps: mixing the above materials, adding appropriate amount of water, stirring, making into paste, degassing, storing paste, bottling, and packaging to obtain the final product.
Example 2:
a natural full herbal foam toothpaste is composed of the following raw materials in parts by weight: 13 parts of dendrobium extract, 15 parts of honeysuckle extract, 12 parts of moutan bark extract, 10 parts of fructus amomi extract, 15 parts of poria cocos extract, 12 parts of mint extract, 10 parts of clove extract, 17 parts of purple daisy extract, 4 parts of sodium phytate and 2 parts of amino acid.
The preparation method of the natural full-herbal foam toothpaste comprises the following steps:
1) the preparation method of the dendrobium extract comprises the following steps: pulverizing herba Dendrobii, soaking in 5 times of water for 30min, decocting for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the honeysuckle extract comprises the following steps: extracting flos Lonicerae with 6 times of 75% ethanol under reflux for 1.5 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the moutan bark extract comprises the following steps: pulverizing cortex moutan, adding 1.5 times of 70% ethanol, and performing CO treatment2Performing supercritical extraction at 35MPa for 2h and 45 ℃;
the preparation method of the fructus amomi extract comprises the following steps: crushing fructus Amomi, placing in ultrasonic extraction tank, adding 4 times of 70% ethanol, soaking for 30min, heating to 37 deg.C, performing ultrasonic treatment for 1 hr with ultrasonic power of 600W, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the tuckahoe extract comprises the following steps: pulverizing Poria, soaking in 6 times of water for 30min, decocting for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the mint extract comprises the following steps: pulverizing herba Menthae, adding 7 times of 75% ethanol, cold soaking for 22 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the clove extract comprises the following steps: adding 75% ethanol 6 times the amount of the purple daisy, heating, refluxing, extracting for 2h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the purple daisy extract comprises the following steps: adding 75% ethanol 6 times the amount of the purple daisy, heating, refluxing, extracting for 2h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature.
2) Mixing herba Dendrobii extract, flos Lonicerae extract, cortex moutan extract, fructus Amomi extract, Poria extract, herba Menthae extract, flos Caryophylli extract, purple daisy extract, sodium phytate, and amino acids, adding appropriate amount of water, stirring, making into paste, degassing, storing paste, bottling, and packaging to obtain the final product.
Example 3:
a natural full herbal foam toothpaste is composed of the following raw materials in parts by weight: 12 parts of dendrobium extract, 14 parts of honeysuckle extract, 14 parts of moutan bark extract, 9 parts of fructus amomi extract, 17 parts of poria cocos extract, 11 parts of mint extract, 9 parts of clove extract, 16 parts of purple daisy extract, 3 parts of sodium phytate and 1 part of amino acid.
The preparation method of the natural full-herbal foam toothpaste comprises the following steps:
1) the preparation method of the dendrobium extract comprises the following steps: pulverizing herba Dendrobii, soaking in 4 times of water for 30min, decocting for 1h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the honeysuckle extract comprises the following steps: extracting flos Lonicerae with 5 times of 70% ethanol under reflux for 1 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the moutan bark extract comprises the following steps: pulverizing cortex moutan, adding 1 time of 75% ethanol, and performing CO treatment2Performing supercritical extraction at the extraction pressure of 20MPa for 3h and the temperature of 50 ℃;
the preparation method of the fructus amomi extract comprises the following steps: crushing fructus Amomi, placing in ultrasonic extraction tank, adding 5 times of 75% ethanol, soaking for 30min, heating to 35 deg.C, performing ultrasonic treatment for 40min with ultrasonic power of 550W, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the tuckahoe extract comprises the following steps: pulverizing Poria, soaking in 5 times of water for 30min, decocting for 1.5 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the mint extract comprises the following steps: pulverizing herba Menthae, adding 6 times of 80% ethanol, cold soaking for 25 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the clove extract comprises the following steps: extracting flos Caryophylli with 5 times of 70% ethanol under reflux for 1.5 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature
The preparation method of the purple daisy extract comprises the following steps: adding 70% ethanol 5 times the amount of the purple daisy, heating, refluxing, extracting for 1.5h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature.
2) Mixing herba Dendrobii extract, flos Lonicerae extract, cortex moutan extract, fructus Amomi extract, Poria extract, herba Menthae extract, flos Caryophylli extract, purple daisy extract, sodium phytate, and amino acids, adding appropriate amount of water, stirring, making into paste, degassing, storing paste, bottling, and packaging to obtain the final product.
Example 4:
a natural full herbal foam toothpaste is composed of the following raw materials in parts by weight: 15 parts of dendrobium extract, 10 parts of honeysuckle extract, 15 parts of moutan bark extract, 7 parts of fructus amomi extract, 20 parts of poria cocos extract, 10 parts of mint extract, 7 parts of clove extract, 20 parts of purple daisy extract, 2 parts of sodium phytate and 3 parts of amino acid.
The preparation method of the natural full-herbal foam toothpaste comprises the following steps:
1) the preparation method of the dendrobium extract comprises the following steps: pulverizing herba Dendrobii, soaking in 6 times of water for 30min, decocting for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the honeysuckle extract comprises the following steps: extracting flos Lonicerae with 4 times of 80% ethanol under reflux for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the moutan bark extract comprises the following steps: pulverizing cortex moutan, adding1 time of 75% ethanol for CO2Performing supercritical extraction at 40MPa for 1h and 40 deg.C;
the preparation method of the fructus amomi extract comprises the following steps: crushing fructus Amomi, placing in ultrasonic extraction tank, adding 4 times of 80% ethanol, soaking for 30min, heating to 40 deg.C, performing ultrasonic treatment for 0.5 hr with ultrasonic power of 650W, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the tuckahoe extract comprises the following steps: pulverizing Poria, soaking in 4 times of water for 30min, decocting for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the mint extract comprises the following steps: pulverizing herba Menthae, adding 8 times of 70% ethanol, cold soaking for 25 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the clove extract comprises the following steps: adding flos Caryophylli into 4 times of 80% ethanol, heating and reflux-extracting for 2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the purple daisy extract comprises the following steps: adding 80% ethanol 4 times the amount of the purple daisy, heating, refluxing, extracting for 2h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature.
2) Mixing herba Dendrobii extract, flos Lonicerae extract, cortex moutan extract, fructus Amomi extract, Poria extract, herba Menthae extract, flos Caryophylli extract, purple daisy extract, sodium phytate, and amino acids, adding appropriate amount of water, stirring, making into paste, degassing, storing paste, bottling, and packaging to obtain the final product.
Example 5:
a natural full herbal foam toothpaste is composed of the following raw materials in parts by weight: 10 parts of dendrobium extract, 15 parts of honeysuckle extract, 10 parts of moutan bark extract, 12 parts of fructus amomi extract, 15 parts of poria cocos extract, 15 parts of mint extract, 12 parts of clove extract, 15 parts of purple daisy extract, 5 parts of sodium phytate and 1 part of amino acid.
The natural full herbal mousse dentifrice is prepared as in example 4.
To further illustrate the effect of the toothpaste prepared according to the present invention, the toothpaste effect evaluation was performed from the following aspects:
(1) and (3) bacteriostatic evaluation:
taking common pathogenic bacteria in oral cavity as an antibacterial object, culturing at constant temperature of 35 ℃ by using a hydrolyzed casein liquid culture medium, taking the toothpaste prepared in the embodiment 2 of the invention as an experimental object, diluting the toothpaste into a group of gradient samples with different concentrations by using water, and measuring the antibacterial performance of the toothpaste. The experimental results are shown in table 1 below.
TABLE 1 bacteriostatic test of toothpaste on pathogenic bacteria
| Bacterial strain | 1：10 | 1：200 | 1：400 | 1：600 |
| Streptococcus mutans | Sterile growth | Sterile growth | Sterile growth | Growth with bacteria |
| Porphyromonas gingivalis | Sterile growth | Sterile growth | Sterile growth | Growth with bacteria |
| Candida albicans | Sterile growth | Sterile growth | Sterile growth | Growth with bacteria |
As can be seen from the table 1, the prepared toothpaste has an antibacterial effect after being diluted by 400 times, which shows that the toothpaste has a good inhibition effect on common pathogenic bacteria in the oral cavity.
(2) Anti-inflammatory evaluation:
the experimental method comprises the following steps: 30 healthy male KM mice, weighing 18-22g, were randomly divided into 3 groups of 10 mice each. Blank (saline 0.2 ml/body), experimental group (0.1 g/body, prepared as in example 2), control group (dexamethasone tablets, 0.05 g/body). The administration route is intragastric administration, 1 time per day, 7 days of continuous administration, 30 minutes after the last administration, 0.1 ml/mouse of dimethylbenzene is uniformly coated on the inner and outer surfaces of the right auricle of each mouse, and the left auricle is used as a self blank control without treatment. Mice were sacrificed 1 hour after xylene exposure, ears were cut, aligned, ear was punched out with an 8mm punch, weighed with an analytical balance, and swelling values were calculated: swelling values were from right to left, and the results are shown in table 2.
TABLE 2 effect of toothpaste samples on acute inflammation swelling of mouse auricle caused by xylene
| Group of | Dosage form | Swelling number (mg) |
| Blank group | Physiological saline 0.2 ml/bag | 17.02±2.99 |
| Experimental group | Example 2 toothpaste 0.1 g/toothpaste | 10.85±2.38 |
| Control group | Dexamethasone 0.05 g/body | 9.77±2.15 |
As can be seen from Table 2, the weight of acute inflammation swelling auricles of mice in the experimental group and the control group is obviously reduced, and compared with the blank group, the weight of acute inflammation swelling auricles of mice in the experimental group and the control group is obviously different, and the difference has statistical significance (P < 0.05), which indicates that the toothpaste disclosed by the invention has an obvious anti-inflammatory effect on acute inflammation. (3) Clinical use efficacy evaluation 100 patients with oral diseases with gingivitis and gingival pain, the age is 15-65 years, the toothpaste prepared by the method of the invention in example 3 is used for brushing teeth once in the morning and at night every day, the teeth are brushed by a horizontal vibration method for 2-3 minutes, and the used toothpaste body is about 1-1.5 cm. After the medicine is continuously used for 2 weeks, the effective rate reaches 100%, the gum of a gingivitis patient is normal in color and plump, the gum does not have the phenomenon of swelling and bleeding, the pain of the gum pain patient disappears, and no adverse reaction occurs. The toothpaste of the invention has obvious improvement effect on gingivitis and gingival pain. It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (3)
1. The natural full-herbal foam toothpaste is characterized by comprising the following raw materials in parts by weight: 10-15 parts of dendrobium extract, 10-15 parts of honeysuckle extract, 10-15 parts of moutan bark extract, 7-12 parts of fructus amomi extract, 15-20 parts of poria cocos extract, 10-15 parts of mint extract, 7-12 parts of clove extract, 15-20 parts of purple daisy extract, 2-5 parts of sodium phytate and 1-3 parts of amino acid;
the preparation method of the dendrobium extract comprises the following steps: pulverizing herba Dendrobii, soaking in 4-6 times of water for 30min, decocting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the honeysuckle extract comprises the following steps: extracting flos Lonicerae with 4-6 times of 70-80% ethanol under reflux for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the moutan bark extract comprises the following steps: pulverizing cortex moutan, adding 1-2 times of 65-75% ethanol, and performing supercritical CO2 extraction at 40-50 deg.C under 20-40MPa for 1-3 hr;
the preparation method of the fructus amomi extract comprises the following steps: pulverizing fructus Amomi, placing in ultrasonic extraction tank, adding 4-6 times of 70-80% ethanol, soaking for 30min, heating to 35-40 deg.C, performing ultrasonic treatment for 0.5-1h, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the tuckahoe extract comprises the following steps: pulverizing Poria, soaking in 4-6 times of water for 30min, decocting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the mint extract comprises the following steps: pulverizing herba Menthae, adding 6-8 times of 70-80% ethanol, cold soaking for 20-25 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the clove extract comprises the following steps: adding 4-6 times of 70-80% ethanol into flos Caryophylli, heating, reflux extracting for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature;
the preparation method of the purple daisy extract comprises the following steps: adding 70-80% ethanol 4-6 times the amount of Echinacea purpurea, reflux extracting under heating for 1-2 hr, filtering, concentrating the filtrate under reduced pressure, and drying at low temperature.
2. The natural full herbal foam toothpaste of claim 1 wherein the raw materials comprise, in parts by weight: 13 parts of dendrobium extract, 15 parts of honeysuckle extract, 12 parts of moutan bark extract, 10 parts of fructus amomi extract, 15 parts of poria cocos extract, 12 parts of mint extract, 10 parts of clove extract, 17 parts of purple daisy extract, 4 parts of sodium phytate and 2 parts of amino acid.
3. The natural full herbal foam toothpaste as claimed in claim 2, wherein the fructus Amomi extract is prepared by a method wherein the ultrasonic power is 550-650W.
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| CN1078882A (en) * | 1992-05-20 | 1993-12-01 | 吴海元 | Multipurpose anti-caries liquid tooth-paste and compound method thereof |
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| CN104666185B (en) * | 2015-02-13 | 2018-01-02 | 成都润兴消毒药业有限公司 | A kind of liquid tooth paste and preparation method thereof |
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| JP2001233751A (en) * | 2000-02-22 | 2001-08-28 | Lion Corp | Liquid dental caries-preventing agent composition |
| TW201132359A (en) * | 2010-03-24 | 2011-10-01 | Zhi-Jian Chen | Teeth-cleaning mousse type toothpaste without grinding agent and having a slight-bubbling function, and manufacturing method thereof |
| JP2015086164A (en) * | 2013-10-30 | 2015-05-07 | ライオン株式会社 | Liquid oral composition |
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