CN106580736A - Solubilizing grease composition, application thereof and cosmetic prepared from same - Google Patents

Solubilizing grease composition, application thereof and cosmetic prepared from same Download PDF

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Publication number
CN106580736A
CN106580736A CN201611069147.1A CN201611069147A CN106580736A CN 106580736 A CN106580736 A CN 106580736A CN 201611069147 A CN201611069147 A CN 201611069147A CN 106580736 A CN106580736 A CN 106580736A
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Prior art keywords
peg
fatss
compositionss
alcohol
type
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CN201611069147.1A
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Chinese (zh)
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CN106580736B (en
Inventor
何廷刚
张兵
朱思阳
艾勇
胡丽云
陈洪
黄垂凡
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Guangdong Heji Biotechnology Co., Ltd.
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Guangzhou Heji Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/49Solubiliser, Solubilising system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a solubilizing grease composition, an application thereof and a cosmetic prepared by using the composition. The composition comprises, by weight, 1 part of vitamin E or its derivatives, 1-3 parts of higher alcohols, 2-5 parts of low polymerization degree PEG-structure-carrying non-ionic surface active agent, 2-5 parts of high polymerization degree PEG-structure-carrying non-ionic surface active agent and 60-120 parts of lower alcohols. The prepared solubilizing grease composition can be adopted in lower alcohol or non-alcohol cosmetics such as astringent, essence, facial mask, can effectively promote the water solubility of the skin effective components such as vitamins and its derivatives, can compensate oil content to skin, and increase moisture level of the skin. The solubilizing grease composition has the advantages of causing little oily and greasy feeling to the skin, having little stimulation to the skin, being suitable for most water aqua systems, and causing no influence to the system stability.

Description

A kind of compositionss and its application and cosmetics prepared therefrom of solubilized oils and fatss
Technical field
The present invention relates to cosmetic field, the compositionss of more particularly to a kind of solubilized oils and fatss and its application and prepared therefrom Cosmetics.
Background technology
With the improvement of people's living standards, cosmetics have come into huge numbers of families, and people are needed to high-quality cosmetic Ask increasingly serious.Due to needing, may require that sometimes some oils and fatss, active matter, essence, preservative are added in selection in water-based system Deng oil soluble material.But, under general case, these lipophilic components are difficult to dissolve in formula system, it is impossible to form homogeneous.Cause This, solubilizing agent just serves vital effect in this kind of cosmetics, and solubilizing agent can help lipophilic component to be dissolved in water In, and form the homogeneous system of transparent and homogeneous.
On market, solubilizing agent composition is mainly based on nonionic surfactant and anion surfactant.By some Nonpolar Low grease carries out solubilising, and generally requiring the high nonionic table of a large amount of HLB values and living carries out solubilising, but by vitamin e, The nonpolar high oils and fatss such as tocopherol acetass solubilising in water, to transparent, made the preparations such as cosmetic water and is difficult to, its Often using substantial amounts of high polymerization degree nonionic surfactant, but solution be also difficult to it is transparent, it is impossible to ensure Cutaneous permeation inhale Receive.Additionally, using the nonionic surfactant of a large amount of high polymerization degrees, glutinous soapy feeling and zest can be caused to skin.
The content of the invention
In order to overcome the shortcoming that prior art is present and deficiency, the primary and foremost purpose of the present invention is to provide a kind of solubilized oils and fatss Compositionss, said composition is applied in water system cosmetics, can make solution solubilising to transparent, and the glutinous soapy feeling of skin is low, zest It is little.
The present invention is achieved by the following technical solutions:
A kind of compositionss of solubilized oils and fatss, comprising component:Vitamin E or derivatives thereof, higher alcohol, low polymerization degree are carried PEG structure nonionic surfactants, high polymerization degree carry PEG structures nonionic surfactant and lower alcohol, wherein, dimension life Plain E or derivatives thereof:Higher alcohol:Low polymerization degree carries PEG structure nonionic surfactants:High polymerization degree carries PEG structures Nonionic surfactant:The weight ratio of lower alcohol is 1:1-3:2-5:2-5:60-120.
The present invention not according to HLB value selecting tween, but by being conceived to the polarity of water, oil components The technical method found with the PEG degree of polymerization of nonionic surfactant.Oil components are vitamin and its derivant, are non- Polar oil.However, the polarity highest of water, high polymerization degree is soluble in water with PEG structure nonionic surfactants, but can not be molten In oil.The present invention by addition positioned at the rwo intermediate polarity low polymerization degree with PEG structures nonionic surfactant and Higher alcohol so as to become both materials compatible.Additionally, being located at water and high polymerization degree with PEG structure nonionics plus polarity Lower alcohol between surfactant, make oil components in water can solubilising to transparent.From the point of view of the chemical constitution of higher alcohol, its The end of alkyl carries hydroxyl, and in oil components, polarity is high.Polarity of the low polymerization degree with PEG structure nonionic surfactants Positioned at higher alcohol and high polymerization degree between the nonionic surfactant with PEG structures, both are all solvable.The present invention is by grinding Study carefully and higher alcohol, low polymerization degree are carried into PEG structure non-ionic surfaces with PEG structure nonionic surfactants, high polymerization degree Activating agent and lower alcohol are combined with oil components, and the amount of each component is controlled in certain proportion so as to Become the intermediate polarity connectionist of water and oil components, can be by oil components small dispersion and solubilising is to transparent.
PEG structure nonionic surfactants, Gao Ju are carried according to Vitamin E or derivatives thereof, higher alcohol, low polymerization degree The right polar relationship between PEG structures nonionic surfactant and lower alcohol, selects respective ratio to be 1:1-3:2- 5:2-5:60-120.If low polymerization degree and high polymerization degree are very few with PEG structure nonionic surfactants, higher alcohol mistake It is many, then polarity of the high polymerization degree with PEG structure nonionic surfactants with the polarities match of water, but can not can dissolve It is in higher alcohol, so as to there is lamination or even muddy.If low polymerization degree and high polymerization degree carry PEG structure nonionics Surfactant is excessive, and higher alcohol is very few, then polarity of the low polymerization degree with PEG structure nonionic surfactants can not be with Higher alcohol polarities match, also occurs corresponding layering, or even muddy.
As preferred version of the invention further, the compositionss of solubilized oils and fatss of the present invention, Vitamin E or its spread out It is biological:Higher alcohol:Low polymerization degree carries PEG structure nonionic surfactants:High polymerization degree carries PEG structure non-ionic surfaces Activating agent:The weight ratio of lower alcohol is 1:2:3-4:3-4:80-100.
Wherein, the vitamin derivative is tocopherol acetass, vitamin e succinate, Macrogol 1000 dimension life Plain E succinates.
Wherein, during the higher alcohol is octyl dodecanol, isooctadecanol, myristyl alcohol, lauryl alcohol, hexyldecanol or oleyl alcohol One or more, preferably octyl dodecanol, isooctadecanol or oleyl alcohol.
Wherein, the degree of polymerization of the high polymerization degree with PEG structure nonionic surfactants is 30-80, is chosen in particular from Polyoxyethylene fatty glyceride type, polyoxyethylene hardened castor oil fatty acid ester type, polyoxyethylene hardened castor oil type, PCA are different Stearate polyoxyethylene hardened castor oil type, polyoxyethylene fatty acid type, polyoxyethylene sorbitol type, polyoxyethylene alkyl ether One or more in type, one kind in preferred oleth -50, Cremophor RH40 or PEG-60 castor oil hydrogenated or It is several.
Wherein, the degree of polymerization of the low polymerization degree with PEG structure nonionic surfactants is 6-20, is chosen in particular from gathering Oxygen ethylene fatty acid glycerine type, polyoxyethylene hardened castor oil fatty acid ester type, polyoxyethylene hardened castor oil type, PCA are different hard Fat acid ester polyoxyethylene hardened castor oil type, polyoxyethylene fatty acid type, polyoxyethylene sorbitol type, polyoxyethylene alkyl ether-type In one or more, preferred PEG-6 iso stearic acid of glycerine ester, PEG-8 iso stearic acid of glycerine ester, PEG-7 glyceryl cocoates Or one or more in PEG-20 polysorbate.
Wherein, the lower alcohol for C2-C9 alcohol apoplexy due to endogenous wind one or more, preferably glycerol, Propylene Glycol, butanediol, different One or more in pentanediol, hexanediol, 1,2- pentanediols, ethohexadiol, ethohexadiol, dipropylene glycol or diglycerol.
The preparation method of the compositionss of the above-mentioned a kind of solubilized oils and fatss of the present invention is by Vitamin E or derivatives thereof, senior Alcohol, low polymerization degree with PEG structure nonionic surfactants, high polymerization degree carry PEG structures nonionic surfactant and Lower alcohol at 80 DEG C, dissolves which by stirring, reaches solubilizing effect in proportion.
Present invention also offers application of the compositionss of above-mentioned solubilized oils and fatss in cosmetics, food or health product.
Present invention also offers a kind of cosmetics, the compositionss comprising above-mentioned solubilized oils and fatss.
Preferably, the addition of the compositionss of the solubilized oils and fatss is the 5-15% of whole cosmetics gross mass.
In the compositionss of the solubilized oils and fatss of the invention described above, do not damaging in the range of effect of the present invention, can be any Coordinate the composition that generally may be fitted in cosmetics to prepare cosmetics.This any condition includes preservative, wetting agent, purple Ultraviolet absorbers, antioxidant, Ph regulators etc..Its consumption is the conventional amount used for preparing cosmetics.
The present invention compared with prior art, has the advantages that:
(1) present invention is by carrying PEG structure nonionic surfactants, high polymerization degree band by higher alcohol, low polymerization degree There are PEG structures nonionic surfactant and lower alcohol to be combined with oil components, and the amount of each component is controlled one In fixed proportion, the compositionss of the solubilized oils and fatss for preparing are applied to the low alcohol such as astringent, essence, facial film, without alcohol In water preparation cosmetics, it is soluble in water to effectively facilitate the skin effective ingredient such as vitamin and its derivant, can supplement to skin Oil, the moist degree for increasing skin;
(2) nonionic surfactant containing PEG structures used in the compositionss of solubilized oils and fatss prepared by the present invention is used Amount is few, and the glutinous soapy feeling of skin is low, zest is little, it is adaptable to most of water preparation system, and system stability will not be had an impact;
(3) preparation method of the present invention is simple to operate, easily realizes, prepared cosmetics cost performance is high, low cost.
Specific embodiment
The present invention is further illustrated below by specific embodiment, following examples are the present invention preferably embodiment party Formula, but embodiments of the present invention are not limited by following embodiments.
Raw material of the present invention derives from commercial products.
Performance test methods:
The method of testing of appearance transparence stability:
Transparent toner/smoothing toner is taken, 40 DEG C of storages 1 month, 25 DEG C of room temperature is placed in and is deposited 1 month, the storage 1 month of 5 DEG C of low temperature, it is extensive It is multiple to observe appearance transparence to room temperature.
The method of testing of the particle diameter of vitamin or derivatives thereof:Tested using LS900 type laser particle size analyzers, surveyed Examination scope:0.05~500 μm;Input mode:Wet method, circular sample feeder and static sample pond;
Repeatability error:<3%;Testing time:1-2 minutes;Standalone probe unit number:53;Light source category:Helium-neon swashs Light, power:2.0mW, wavelength:0.6328μm;Working environment:Temperature:5-35 DEG C, humidity:< 85%.
Transmittance method of testing:Using ultraviolet-uisible spectrophotometer UV1000, Exposure Metering:Single beam;Wave-length coverage: 190.0~1100.0nm;Spectral bandwidth:2nm;Transmittance ranges:0~200%T;Range of absorbency:- 0.3~3Abs;Light source: Deuterium lamp, halogen tungsten lamp;Dispersion element:Grating, 1200L/mm;Detector:Silicon photo diode;Use environment temperature:5 DEG C~35 DEG C; Use environment relative humidity:≤ 85%.
The preparation of the compositionss of solubilized oils and fatss:
By 1 formula of table, Vitamin E or tocopherol acetass, higher alcohol, low polymerization degree are carried into PEG structure nonionic tables Face activating agent, high polymerization degree carry PEG structures nonionic surfactant and lower alcohol in proportion at 80 DEG C, are made by stirring Its dissolving, you can obtain the compositionss of solubilized oils and fatss.
Table 1:The composition (weight portion) of the compositionss of solubilized oils and fatss
Continued 1
Embodiment 1-13 and comparative example 1-5:
By 2 formula of table, the compositionss of solubilized oils and fatss obtained above, preservative, pure water proportionally, at 40 DEG C, are stirred Mix to be mixed with and obtain transparent toner/smoothing toner, test its performance, results of property is as shown in table 2:
The composition and the performance test results (%) of 2 embodiment 1-13 of table and the transparent toner/smoothing toner of comparative example 1-5
Continued 2:
The present invention can be seen that by the result of 2 embodiment of table and comparative example higher alcohol, low polymerization degree are carried into PEG structures Nonionic surfactant, high polymerization degree carry PEG structures nonionic surfactant and lower alcohol and oil components and carry out Combination, and the amount of each component is controlled in certain proportion, the compositionss of the solubilized oils and fatss for preparing are applied to soft In skin water, it is soluble in water to effectively facilitate the skin effective ingredient such as vitamin and its derivant, can solubilising to transparent.

Claims (10)

1. a kind of compositionss of solubilized oils and fatss, it is characterised in that comprising component:It is Vitamin E or derivatives thereof, higher alcohol, oligomeric It is right to carry PEG structures nonionic surfactant and lower alcohol with PEG structure nonionic surfactants, high polymerization degree, Wherein, Vitamin E or derivatives thereof:Higher alcohol:Low polymerization degree carries PEG structure nonionic surfactants:High polymerization degree band There are PEG structure nonionic surfactants:The weight ratio of lower alcohol is 1:1-3:2-5:2-5:60-120, preferably 1:1:3-4: 3-4:80-100.
2. compositionss of solubilized oils and fatss according to claim 1, it is characterised in that the vitamin derivative is tocopherol One or more in acetass, vitamin e succinate or polyethylene glycol 1000 vitamin E succinic acid ester.
3. compositionss of solubilized oils and fatss according to claim 1, it is characterised in that the higher alcohol be octyl dodecanol, One or more in isooctadecanol, myristyl alcohol, lauryl alcohol, hexyldecanol or oleyl alcohol, preferably octyl dodecanol, different Hard Fat One or more in alcohol or oleyl alcohol.
4. compositionss of solubilized oils and fatss according to claim 1, it is characterised in that the high polymerization degree carries PEG structures The degree of polymerization of nonionic surfactant is 30-80, is chosen in particular from polyoxyethylene fatty glyceride type, polyoxyethylene hardened Semen Ricini Fatty acid oil ester type, polyoxyethylene hardened castor oil type, PCA isostearate polyoxyethylene hardened castor oil types, Polyethylene oxide One or more in fatty acid type, polyoxyethylene sorbitol type, polyoxyethylene alkyl ether-type, preferred oleth -50, PEG- One or more in 40 castor oil hydrogenated or PEG-60 castor oil hydrogenated.
5. compositionss of solubilized oils and fatss according to claim 1, it is characterised in that the low polymerization degree carries PEG structures The degree of polymerization of nonionic surfactant is 6-20, is chosen in particular from polyoxyethylene fatty glyceride type, polyoxyethylene hardened Semen Ricini Fatty acid oil ester type, polyoxyethylene hardened castor oil type, PCA isostearate polyoxyethylene hardened castor oil types, Polyethylene oxide One or more in fatty acid type, polyoxyethylene sorbitol type, polyoxyethylene alkyl ether-type, the different Hard Fat of preferred PEG-6 glycerol One kind or several in acid esters, PEG-8 iso stearic acid of glycerine ester, PEG-7 glyceryl cocoates or PEG-20 Polyoxyethylene Sorbitan Monooleates Kind.
6. compositionss of solubilized oils and fatss according to claim 1, it is characterised in that the lower alcohol is C2-C9 alcohol apoplexy due to endogenous wind One or more.
7. compositionss of solubilized oils and fatss according to claim 6, it is characterised in that the lower alcohol be glycerol, Propylene Glycol, One kind in butanediol, isoprene, hexanediol, 1,2- pentanediols, ethohexadiol, ethohexadiol, dipropylene glycol or diglycerol Or it is several.
8. application of the compositionss of the solubilized oils and fatss described in any one of claim 1-7 in cosmetics, food or health product.
9. a kind of cosmetics, the compositionss comprising the solubilized oils and fatss described in any one of claim 1-7.
10. cosmetics according to claim 9, it is characterised in that the addition of the compositionss of the solubilized oils and fatss is whole The 5-15% of individual cosmetics gross mass.
CN201611069147.1A 2016-11-29 2016-11-29 A kind of composition and its application and cosmetics prepared therefrom of solubilising grease Active CN106580736B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791015A (en) * 2021-01-25 2021-05-14 湖北煜韩环境科技有限公司 Essence solubilizer and preparation method thereof
CN115810437A (en) * 2022-11-16 2023-03-17 江苏爱朋医疗科技股份有限公司 Conductive liquid and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013154359A1 (en) * 2012-04-13 2013-10-17 (주)아모레퍼시픽 Nano-emulsion composition and method for producing the same
CN105596236A (en) * 2016-01-18 2016-05-25 上海蔚科精细化工有限公司 Low-foam solubilizer composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013154359A1 (en) * 2012-04-13 2013-10-17 (주)아모레퍼시픽 Nano-emulsion composition and method for producing the same
CN105596236A (en) * 2016-01-18 2016-05-25 上海蔚科精细化工有限公司 Low-foam solubilizer composition

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Title
广州市花安堂生物科技有限公司: "奢睿男士保湿精华水", 《国产非特殊用途化妆品备案服务平台》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112791015A (en) * 2021-01-25 2021-05-14 湖北煜韩环境科技有限公司 Essence solubilizer and preparation method thereof
CN112791015B (en) * 2021-01-25 2022-10-04 湖北煜韩环境科技有限公司 Essence solubilizer and preparation method thereof
CN115810437A (en) * 2022-11-16 2023-03-17 江苏爱朋医疗科技股份有限公司 Conductive liquid and preparation method thereof

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