CN106539779A - A kind of formula of ointment shape content composition soft capsule - Google Patents
A kind of formula of ointment shape content composition soft capsule Download PDFInfo
- Publication number
- CN106539779A CN106539779A CN201611194323.4A CN201611194323A CN106539779A CN 106539779 A CN106539779 A CN 106539779A CN 201611194323 A CN201611194323 A CN 201611194323A CN 106539779 A CN106539779 A CN 106539779A
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- CN
- China
- Prior art keywords
- soft capsule
- formula
- content composition
- ointment shape
- shape content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
A kind of formula of ointment shape content composition soft capsule that the present invention is provided, including 100 300g of gelatin, 100 300g of water, 40 120g of glycerine, 0.1 0.3g of pigment, 32 96g of propolis, 60 180g of wheat-germ oil, 4 12g of vitamin E, 3 9g of amino acid/11 3g and linoleic acid, step is simple, it is easy to operate, it is easy to make, the stability of soft capsule is high, it is easy to chew, soft capsule intensity is higher, content can stable for extended periods of time, it is easy to storage, cost is relatively low, can more meet the demand of producer.
Description
Technical field
The present invention relates to soft capsule technical field, particularly a kind of formula of ointment shape content composition soft capsule.
Background technology
Soft capsule belongs to a kind of manner of packing of capsule, is common in medicine or health food.It is by liquid medicine or
A kind of capsule made by during juicy fruit body medicine Jing process is sealed in soft capsule material.Soft capsule material is by gelatinum pro capsulae, sweet
Oily or other suitable pharmaceutic adjuvants are independent or are mixed.Soft capsule is referred to directly to be encapsulated a certain amount of liquid medicine, or
Solid drugs are dissolved or dispersed in suitable excipient and make solution, suspension, emulsion or semisolid, be sealed in it is spherical or
Capsule in oval soft capsule material.The intracapsular content of existing flexible glue is carried out to softgel shell after moisture absorption, makes softgel shell hardness
It is higher, it is unfavorable for the chewing of user, soft capsule preparation process in preparation process is loaded down with trivial details, relatively costly, can not meet producer
Demand.
The content of the invention
Problem to be solved by this invention is to provide a kind of formula of ointment shape content composition soft capsule, solves existing flexible glue
Intracapsular content is carried out to softgel shell after moisture absorption, makes softgel shell hardness higher, is unfavorable for the chewing of user, prepared by soft capsule
In journey, preparation process is loaded down with trivial details, relatively costly, can not meet the problem of the demand of producer.
To solve problem above scheme of the present invention：
A kind of formula of ointment shape content composition soft capsule, wherein, constituent is as follows by weight：
Gelatin 100-300g；
Water 100-300g；
Glycerine 40-120g；
Pigment 0.1-0.3g；
Propolis 32-96g；
Wheat-germ oil 60-180g；
Vitamin E 4-12g；
Amino acid/11-3g；
Linoleic acid 3-9g.
A kind of formula of above-mentioned ointment shape content composition soft capsule, wherein, the weight of described gelatin, water, glycerine and pigment
Amount ratio is 100：100：40：0.1.
A kind of formula of above-mentioned ointment shape content composition soft capsule, wherein, described propolis, wheat-germ oil, vitamin
E, amino acid are 32 with linoleic part by weight：60：4：1：3.
The beneficial effect of this programme：
A kind of formula of ointment shape content composition soft capsule that the present invention is provided, including it is gelatin 100-300g, water 100-300g, sweet
Oily 40-120g, pigment 0.1-0.3g, propolis 32-96g, wheat-germ oil 60-180g, vitamin E 4-12g, amino acid/11-3g with
Linoleic acid 3-9g, step are simple, it is easy to operate, easy to make, and the stability of soft capsule is high, it is easy to chew, soft capsule intensity compared with
Height, content can stable for extended periods of time, it is easy to stores, cost is relatively low, can more meet the demand of producer.
Specific embodiment
The specific embodiment of the present invention is described in further detail below by way of specific embodiment.
Embodiment one
A kind of formula of ointment shape content composition soft capsule, wherein, constituent is as follows by weight：
Gelatin 100g；
Water 100g；
Glycerine 40g；
Pigment 0.1g；
Propolis 32g；
Wheat-germ oil 60g；
Vitamin E 4g；
Amino acid/11 g；
Linoleic acid 3g.
Embodiment two
A kind of formula of ointment shape content composition soft capsule, wherein, constituent is as follows by weight：
Gelatin 200g；
Water 200g；
Glycerine 80g；
Pigment 0.2g；
Propolis 64g；
Wheat-germ oil 120g；
Vitamin E 8g；
Amino acid 2g；
Linoleic acid 6g.
Embodiment three
A kind of formula of ointment shape content composition soft capsule, wherein, constituent is as follows by weight：
Gelatin 300g；
Water 300g；
Glycerine 120g；
Pigment 0.3g；
Propolis 96g；
Wheat-germ oil 180g；
Vitamin E 12g；
Amino acid 3g；
Linoleic acid 9g.
A kind of formula of above-mentioned ointment shape content composition soft capsule, wherein, the weight of described gelatin, water, glycerine and pigment
Amount ratio is 100：100：40：0.1.
A kind of formula of above-mentioned ointment shape content composition soft capsule, wherein, described propolis, wheat-germ oil, vitamin
E, amino acid are 32 with linoleic part by weight：60：4：1：3.
A kind of formula of ointment shape content composition soft capsule that the present invention is provided, including gelatin 100-300g, water 100-
300g, glycerine 40-120g, pigment 0.1-0.3g, propolis 32-96g, wheat-germ oil 60-180g, vitamin E 4-12g, amino
Sour 1-3g and linoleic acid 3-9g, step are simple, it is easy to operate, easy to make, and the stability of soft capsule is high, it is easy to chew, flexible glue
Capsule intensity is higher, and content can stable for extended periods of time, it is easy to stores, cost is relatively low, can more meet the demand of producer.
The only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto, any to be familiar with
Those skilled in the art the invention discloses technical scope in, the change or replacement that can be readily occurred in should all be covered
Within the scope of the present invention.Therefore, protection scope of the present invention should be defined by the protection domain of claims.
Claims (3)
1. a kind of formula of ointment shape content composition soft capsule, wherein, constituent is as follows by weight：
Gelatin 100-300g；
Water 100-300g；
Glycerine 40-120g；
Pigment 0.1-0.3g；
Propolis 32-96g；
Wheat-germ oil 60-180g；
Vitamin E 4-12g；
Amino acid/11-3g；
Linoleic acid 3-9g.
2. the formula of above-mentioned a kind of ointment shape content composition soft capsule, wherein, the weight of described gelatin, water, glycerine and pigment
Ratio is 100：100：40：0.1.
3. the formula of above-mentioned a kind of ointment shape content composition soft capsule, wherein, described propolis, wheat-germ oil, vitamin E,
Amino acid is 32 with linoleic part by weight：60：4：1：3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611194323.4A CN106539779A (en) | 2016-12-21 | 2016-12-21 | A kind of formula of ointment shape content composition soft capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611194323.4A CN106539779A (en) | 2016-12-21 | 2016-12-21 | A kind of formula of ointment shape content composition soft capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106539779A true CN106539779A (en) | 2017-03-29 |
Family
ID=58397748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611194323.4A Pending CN106539779A (en) | 2016-12-21 | 2016-12-21 | A kind of formula of ointment shape content composition soft capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106539779A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103637197A (en) * | 2013-12-03 | 2014-03-19 | 江苏江大源生态生物科技有限公司 | Propolis soft capsule and preparation method thereof |
-
2016
- 2016-12-21 CN CN201611194323.4A patent/CN106539779A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103637197A (en) * | 2013-12-03 | 2014-03-19 | 江苏江大源生态生物科技有限公司 | Propolis soft capsule and preparation method thereof |
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| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170329 |