CN106512046B

CN106512046B - Lifting and rotating device and plasma virus inactivation monitor

Info

Publication number: CN106512046B
Application number: CN201710011701.9A
Authority: CN
Inventors: 赵利俊; 赵利明
Original assignee: Shenzhen Meister Biomedical Engineering Co ltd
Current assignee: Shenzhen Meister Biomedical Engineering Co ltd
Priority date: 2017-01-07
Filing date: 2017-01-07
Publication date: 2022-10-28
Anticipated expiration: 2037-01-07
Also published as: CN106512046A

Abstract

The invention discloses a lifting rotary device and a plasma virus inactivation monitor adopting the lifting rotary device; the lifting and rotating device comprises a vertically arranged main shaft, a lifting mechanism and a lifting driving mechanism, wherein the lifting mechanism lifts along the axial direction of the main shaft; the lifting driving mechanism comprises an upper fixing plate and a lower fixing plate which are horizontally and fixedly arranged on the main shaft; a lifting driving plate horizontally arranged and a lead screw vertically arranged are arranged between the upper fixing plate and the lower fixing plate; the screw rod is connected with the lifting driving plate through a nut; the lifting driving mechanism also comprises a driving piece for driving the screw rod to rotate; the lower end of the lifting mechanism is fixedly connected with the lifting driving plate, and the upper end of the lifting mechanism penetrates through the upper fixing plate; and the upper end and the lower end of the main shaft are both provided with rotating bearings. The lifting and rotating device can meet the equipment operation requirements of all steps of plasma virus inactivation, and the monitoring is more convenient and simpler.

Description

Lifting rotating device and plasma virus inactivation monitor

Technical Field

The invention relates to the technical field of blood component preparation machines, in particular to a lifting rotating device and a plasma virus inactivation monitor.

Background

In order to ensure the safety of the blood plasma for clinical blood transfusion, the blood plasma virus inactivation treatment is required in the preparation process of blood components such as blood plasma, blood cells and the like in the blood station component department. At present, the method adopted for inactivating the plasma virus is a methylene blue photochemical inactivation method, and the method is characterized in that methylene blue is added into plasma and then is subjected to light treatment, wherein the methylene blue can be combined with guanine of virus nucleic acid and lipid envelope of the virus in light, and further the nucleic acid of the virus is broken and the envelope is damaged under the action of visible light, so that the virus completely loses the penetrating, copying and infecting abilities. The comparison of the average levels of plasma globulin, albumin, plasma VIII factor and fibrinogen before and after methylene blue inactivation meets the national standard of more than or equal to 50g/L, and HBV-DNA positive plasma is converted into negative plasma HBV-DNA after virus inactivation, so that the method is an effective plasma virus inactivation measure at present. The operation process of the methylene blue method for plasma virus inactivation can be seen in the attached figures 1 to 2:

firstly, connecting an original plasma bag 1 with a first blood collection bag 2 below through a conduit A, hanging the plasma bag 1 after the conduit A is communicated, transferring plasma from the original plasma blood bag 1 to the first blood collection bag 2 under the action of gravity, dissolving methylene blue powder arranged on the conduit A in the plasma and transferring the methylene blue powder together during transferring, and realizing the addition of the methylene blue to the plasma (shown in figure 1); after the methylene blue is added, the first blood collecting bag 2 is subjected to illumination treatment to inactivate viruses; after the illumination is finished, the first blood collecting bag 2 is connected to the second blood collecting bag 3 through a conduit B with a filter plug in the manner shown in fig. 2, the plasma in the first blood collecting bag 2 flows into the second blood collecting bag 3 through the filter plug, the filter plug can filter out methylene blue from the plasma, and the plasma after the methylene blue is filtered out flows into the second blood collecting bag 3, that is, the inactivated plasma without methylene blue is obtained.

In order to ensure follow-up plasma quality review, process review, problem tracing and the like, the automation device assisting the virus inactivation operation and recording relevant data of the operation process is a plasma virus inactivation monitor. The schematic structure of the current virus inactivation monitor is shown in fig. 3, a blood bag hook 20a is arranged at the upper end of the frame for hanging a blood bag, and a blood bag supporting panel 30a is arranged in the frame 10a to prevent the suspension of the blood bag below. Certainly, the virus inactivation monitor is also provided with a monitoring and sensing device for monitoring the process of adding and filtering methylene blue, and the monitoring and sensing device can timely process and record when blockage, leakage and the like occur in the adding and filtering process so as to ensure that finally prepared blood plasma can be safely used for treatment.

However, when the currently used virus inactivation monitor performs plasma virus inactivation operation, due to the fact that the blood bag and the catheter consumables are different in the two steps of adding methylene blue and filtering the methylene blue, the length of the catheter B in the methylene blue filtering process is obviously longer than that of the catheter A in the adding process; furthermore, when the virus inactivation monitor is used, a large number of blood bags can be placed on the blood bag supporting panel 30a, and the total weight is about dozens of jin, so that the weight-limited blood bag supporting panel 30a is not convenient to prepare into a manually adjustable height form; the two steps of adding and filtering methylene blue are respectively completed under two plasma virus inactivation monitors with different heights of the blood bag supporting panel 30a, so that the step of inactivation operation needs to be separated from the two monitors to be respectively carried out, and the operation and the monitoring are relatively inconvenient.

Disclosure of Invention

The invention mainly aims to provide a lifting rotating device and a plasma virus inactivation monitor adopting the lifting rotating device, aiming at enabling equipment to meet the operation requirements of all steps of plasma virus inactivation and enabling the operation and the monitoring to be more convenient.

In order to achieve the above purpose, the lifting and rotating device provided by the invention comprises a vertically arranged main shaft, a lifting mechanism lifting along the axial direction of the main shaft, and a lifting driving mechanism for driving the lifting mechanism to lift; wherein,

the lifting driving mechanism comprises an upper fixing plate and a lower fixing plate which are horizontally and fixedly arranged on the main shaft;

a lifting driving plate horizontally arranged and a lead screw vertically arranged are arranged between the upper fixing plate and the lower fixing plate; the screw rod is connected with the lifting driving plate through a nut;

the lifting driving mechanism also comprises a driving piece for driving the screw rod to rotate;

the lower end of the lifting mechanism is fixedly connected with the lifting driving plate, and the upper end of the lifting mechanism penetrates through the upper fixing plate;

and rotating bearings are arranged at the upper end and the lower end of the main shaft.

Preferably, the lifting mechanism comprises a sliding sleeve sleeved on the main shaft, the lower end of the sliding sleeve is fixedly connected with the lifting driving plate, and the upper end of the sliding sleeve penetrates through the upper fixing plate;

and/or the lifting mechanism comprises at least two straight rods arranged parallel to the main shaft, the lower ends of the straight rods are fixedly connected with the lifting driving plate, and the upper ends of the straight rods penetrate through the upper fixing plate.

Preferably, the driving part is a motor, and the motor is connected with the screw rod through a transmission part; the transmission part comprises a first synchronous pulley, a second synchronous pulley and a synchronous belt sleeved on the first synchronous pulley and the second synchronous pulley; wherein,

the first synchronous belt wheel is installed on the output end of the motor, and the second synchronous belt wheel is installed on the end portion of the screw rod.

Preferably, the driving piece is a motor, and the motor is connected with the screw rod through a transmission piece; the transmission part comprises a driving gear and a driven gear which are meshed with each other; wherein,

the driving gear is installed on the output end of the motor, and the driven gear is installed on the end portion of the screw rod.

Preferably, at least one transmission gear is arranged between the driving gear and the driven gear in parallel; the driving gear, the transmission gear and the driven gear are sequentially meshed with each other.

Preferably, a vertically arranged lifting guide rod is arranged between the upper fixing plate and the lower fixing plate;

the lifting guide rod penetrates through the lifting driving plate, and a first guide shaft sleeve is installed between the lifting guide rod and the lifting driving plate.

Preferably, the lifting mechanism further comprises a guide piece arranged between the straight rod and the upper fixing plate;

the guide piece is a second guide shaft sleeve arranged between the straight rod and the upper fixing plate;

or the guide piece comprises a base, and three guide bearings which are abutted to the surface of the straight rod are arranged on the base.

Preferably, at least one rotating handle is also directly or indirectly mounted on the main shaft.

Preferably, a vertically arranged supporting side plate is further fixedly arranged between the upper fixing plate and the lower fixing plate;

and the supporting side plate is provided with an optical coupling inductor for detecting the height of the lifting driving plate.

The invention further provides a plasma virus inactivation monitor adopting the lifting and rotating device, which comprises a frame and the lifting and rotating device;

a blood bag suspension plate is arranged on a main shaft of the lifting and rotating device;

blood bag receiver is installed on elevating system top of lifting and drop rotating device, this blood bag receiver with the blood bag hangs the board and corresponds the setting.

By adopting the lifting rotating device and the plasma virus inactivation monitor, the blood bag can be hung and taken by an operator in an inactivation step by rotating besides meeting the requirements of the hanging and storage heights; accurate monitoring of the weight and flow rate of the plasma and collection monitoring of each underlying collection bag is also facilitated.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.

FIG. 1 is a schematic of the addition of methylene blue to plasma in plasma virus inactivation;

FIG. 2 is a schematic diagram of the filtration of methylene blue from plasma during viral inactivation of plasma;

FIG. 3 is a schematic diagram of a conventional monitor for plasma virus inactivation;

FIG. 4 is a schematic diagram of the monitor for plasma virus inactivation according to the present invention;

FIG. 5 is a schematic structural diagram of an embodiment of a lifting/lowering device according to the present invention;

FIG. 6 is a schematic view of a rotating assembly at the upper end of the main shaft of the lifting and rotating device of FIG. 5;

FIG. 7 is a schematic view of a rotating assembly of a lower end of a main shaft in the lifting and rotating device of FIG. 5;

FIG. 8 is a schematic structural view of the lifting/lowering device of FIG. 5 in a raised state;

FIG. 9 is an exploded view of the elevating rotary device of FIG. 5;

FIG. 10 is a schematic structural view of another embodiment of a lifting structure of the lifting rotating apparatus according to the present invention;

FIG. 11 is a schematic view of the guide member of FIG. 10;

FIG. 12 is an exploded view of the guide member of FIG. 11;

FIG. 13 is an exploded view of the transmission member of FIG. 10.

The implementation, functional features and advantages of the present invention will be further described with reference to the accompanying drawings.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that all directional indicators (such as up, down, left, right, front, and back \8230;) in the embodiments of the present invention are only used to explain the relative positional relationship between the components, the motion situation, etc. in a specific posture (as shown in the attached drawings), and if the specific posture is changed, the directional indicators are changed accordingly.

The invention provides a plasma virus inactivation monitor, aiming at enabling equipment to meet the operation requirements of all steps of plasma virus inactivation in plasma virus inactivation operation and enabling the operation and the monitoring to be more convenient. The structure of the monitor for plasma virus inactivation of the present invention is shown in fig. 4, and the monitor for plasma virus inactivation of the present invention comprises a rack 100 and a lifting and rotating device 200, wherein the number of the lifting and rotating device 200 can be 1, or a plurality of lifting and rotating devices 200, which are appropriately arranged and used according to the size of the internal space of the rack, and two are explained and illustrated as preferred embodiments in the present invention.

Further, referring to fig. 5, the lifting and rotating device 200 of this embodiment includes a vertically disposed main shaft 10, a lifting mechanism capable of vertically moving along the main shaft 10, and a lifting and driving mechanism 40 for driving the lifting mechanism to move up and down. Referring to fig. 6 and 7, the upper and lower ends of the main shaft 10 are provided with rotating bearings 101; in this embodiment, the two ends of the main shaft 10 are specifically connected to the rotating bearings 101 through the couplers 102, and the rotating bearings at the two ends of the main shaft 10 are respectively fixed on the rack 100, so that the integral rotation of the lifting and rotating device 200 can be realized; of course, the rotational connection between the main shaft 10 and the frame 100 can also be implemented by other similar rotational structural components capable of realizing integral rotation.

The lifting mechanism adopts a sliding sleeve 20 in the embodiment of fig. 5, the sliding sleeve 20 is slidably sleeved on the main shaft 10, and both ends of the main shaft 10 extend out of the sliding sleeve 20, that is, the length of the sliding sleeve 20 is less than that of the main shaft 10; the elevation rotation apparatus 200 further includes an elevation driving mechanism 40 for driving the elevation movement of the sliding sleeve 20 in the axial direction of the main shaft 10, and the elevation driving mechanism 40 is drivingly connected to the sliding sleeve 20. The lifting drive mechanism 40 of the present embodiment may be mounted on the frame 100, or may be mounted and fixed to the main shaft 10.

Further, referring to fig. 5, 8 and 9 correspondingly, the lifting driving mechanism 40 includes a screw 43 and a driving member 41 (a motor is preferably used in the present embodiment) for driving the screw 43 to rotate; in order to ensure that the lifting process can be normally realized, an upper fixed plate 44 and a lower fixed plate 45 for lifting and applying force and a lifting driving plate 42 which is horizontally arranged between the upper fixed plate 44 and the lower fixed plate 45 and can move up and down are fixedly arranged on the main shaft 10; the screw 43 is then vertically mounted between the upper and lower fixed

plates

44, 45 and passes through the lift driving plate 42; the driving element 41 is fixed on the upper fixing plate 44, the top end of the screw rod 43 is connected with the output end of the driving element 41, and the bottom end of the screw rod 43 can rotate around the axis and is limited on the lower fixing plate 45. The screw 43 penetrates the elevating drive plate 42, and a nut S is interposed therebetween.

In this embodiment, the driving unit 41 is fixed to the main shaft 10 by a screw 43 and a lower fixing plate 45, and the driving unit 41 is rotated by the driving screw 43 and is converted into a driving unit for driving the elevating driving plate 42 to move up and down between the upper fixing plate 44 and the lower fixing plate 45 by a nut S.

It should be noted that, in other embodiments, the lifting driving mechanism 40 may also adopt other driving manners, for example, a telescopic driving manner of an air cylinder. And in the sense of the above embodiment, the screw rod 43 is vertically disposed between the upper fixing plate 44 and the lower fixing plate 45, and whether its end needs to penetrate the upper fixing plate 44 and the lower fixing plate 45 or not may depend on the position of the output end of the driving member 41. For example, in fig. 5, the output end of the driving member (motor) 41 is higher than the upper fixing plate 44, so that for the convenience of connection, the top end of the screw rod 43 is inserted above the upper fixing plate 44 and then connected by the synchronous pulley assembly in fig. 5. Therefore, if the position of the output end of the driving member 41 is located below the upper fixing plate 44 when the internal space and the stroke of the screw 43 are allowed (this is the case with the second embodiment of fig. 10), the top end of the screw 43 does not need to penetrate the upper fixing plate 44 correspondingly. Also, since the driving member 41 can be also installed on the lower fixing plate 45, the manner and position of the lower end of the screw rod 43 may be similar to those of the corresponding arrangement and installation in a natural implementation, and the skilled person can easily refer to the corresponding arrangement.

Further in the above embodiments, in order to ensure the stability of the elevating movement, a guide function part for assisting the elevating is further installed in the apparatus. In the embodiment of fig. 5, two sides of the screw rod 43 are respectively provided with a lifting guide rod 46 parallel to the screw rod 43 (in this embodiment, two sides of the screw rod 43 are respectively provided with one lifting guide rod 46 as an example); wherein, the setting mode of lift guide bar 46 can be: the lifting guide rod 46 penetrates through the lifting driving plate 42, and two ends of the lifting guide rod 46 are respectively fixed on the upper fixing plate 44 and the lower fixing plate 45; the upper fixing plate 44 and the lower fixing plate 45 are connected and fixed through a lifting guide rod 46; meanwhile, the lifting driving plate 42 guides the lifting movement thereof through the lifting guide rod 46, so that the lifting movement thereof is smoother and more stable. Specifically, a guide bushing Z is installed at a joint of the elevation guide bar 46 and the elevation driving plate 42, respectively, so that the relative sliding between the elevation driving plate 42 and the elevation guide bar 46 is more stable and reliable.

Of course, the guide sleeve Z is a relatively general guide auxiliary functional component, and a self-designed three-way guide bearing may also be used for assistance in implementation, for example, the structure of the guide 60 in another embodiment of the present invention can be specifically referred to the description of fig. 10 below. Of course, in addition to the above two modes, the lifting guide rods 46 may also adopt other connection setting modes to achieve the lifting guide function, and the number of the lifting guide rods 46 may also be larger.

Further, referring to fig. 5, 8 and 9, in this embodiment, it is preferable that the driving element 41 is disposed side by side with the screw 43, and the driving element 41 is disposed on a surface of the upper fixing plate 44 facing the lower fixing plate 45; the output end of the driving member 41 is connected to the screw rod 43 through a transmission member.

The driving part 41 and the screw rod 43 are arranged side by side, that is, the driving part 41 and the screw rod 43 are transversely arranged side by side and staggered, so that the driving part 41 is arranged in the area between the upper fixing plate 44 and the lower fixing plate 45, the requirement of the whole lifting driving mechanism 40 on the space height is reduced, and the space is saved; in addition, the driving member 41 is connected to the screw rod 43 through a transmission member to maintain the driving of the screw rod 43, and the rotating speed of the screw rod 43 can be set through the selection of the component size of the transmission member, so that the driving member 41 can control the transmission distance of the screw rod 43 more accurately. Of course, if the space-saving height is not needed, the driving member 41 and the screw 43 may be vertically stacked, that is, disposed on a surface of the upper fixing plate 44 opposite to the lower fixing plate 45, and if the speed reduction design is needed, the two are connected through the speed reducer.

Further, in this embodiment, the transmission member connecting the output end of the driving member 41 and the top end of the screw 43 may adopt a synchronous pulley member shown in fig. 7, which includes a first synchronous pulley 51 coaxially fixed with the output end of the driving member 41, a second synchronous pulley 52 coaxially fixed with the top end of the screw 43, and a synchronous belt 53 connecting the first synchronous pulley 51 and the second synchronous pulley 52; the ratio of the rotation speed of the driver 41 to the lead screw 43 can be adjusted by selecting different sizes of the first and second timing pulleys 51 and 52. Based on the similar transmission function, the transmission member can also be realized by using a gear combination shown in another embodiment in fig. 10, and the following description of fig. 8 can be referred to.

Further, referring to fig. 4-5 and 8-9, two sides of the main shaft 10 of the present embodiment are further provided with supporting side plates 47, respectively, and two ends of the supporting side plates 47 are correspondingly connected and fixed with the upper fixing plate 44 and the lower fixing plate 45; thus, the two supporting side plates 47, the upper fixing plate 44 and the lower fixing plate 45 form a frame-shaped supporting frame, so that the lifting driving mechanism 40 is driven more stably and reliably; on the other hand, the upper fixing plate 44 itself can be fixed on the main shaft 10 through the frame-shaped frame, because when the supporting side plate 47 does not exist, since the upper fixing plate 44 needs to be penetrated by the main shaft 10, and in the case that the sliding sleeve 20 needs to be lifted on the surface of the main shaft 10, the upper fixing plate 44 needs to be connected with the main shaft 10 through other fixing structures, when the supporting side plate 47 is installed, other fixing structures for connection can be omitted. In addition, an optical coupler sensor for detecting the height of the lifting driving plate 43 may be provided on the supporting side plate 47. Alternatively, the lifting driving plate 42 may be provided with an optical coupling sensing piece 48, and one of the supporting side plates 47 may be provided with a sensing seat 49 corresponding to the optical coupling sensing piece 48. The sensing is divided into a receiving module and a transmitting module, and in the lifting process of the lifting driving plate 42, the optical coupling sensing sheet 48 triggers a sensing signal when passing through the position of the sensing seat 49, so that the sensing is more accurate; thereby realizing the position monitoring of the lifting driving plate 42 and facilitating the lifting control of the lifting driving plate 42.

Based on a modified structure similar to the above embodiment, the structure of the elevating portion in the structure of the elevating and rotating device of another embodiment of the present invention is shown with reference to fig. 10. Of course, this embodiment is also realized by relying on the components such as the main shaft 10 in the above embodiment, and referring to fig. 8 in combination with the above-mentioned drawings, the structure of the lifting part adopts the straight rod 46a in fig. 8. The straight rod 46a used in this embodiment has a lower end fixed to the lift driving plate 42a and an upper end directly penetrating above the upper fixing plate 44 a; the straight rod 46a is driven to lift by the lifting driving plate 42a in a mode that the motor drives the screw rod 43 a; and since it can be seen from the figure that there may be a plurality of straight rods 46a, and because of their length and arrangement, they have the function of a lifting guide rod during lifting, the structure similar to the lifting guide rod 46a in the previous embodiment may be omitted compared to the previous embodiment. Some auxiliary lifting guide elements may be added in the lifting process of the straight rod 46a, and the auxiliary lifting guide elements may be similar to the guide shaft sleeve Z in the previous embodiment, or may be the guide element 60 mounted on the straight rod 46a in fig. 8; the guide 60 has three guide bearings which are respectively abutted against the straight bar 46a from three directions of the outer surface of the straight bar 46a to form a clamp to assist the lifting positioning and guiding, and the guide bearings can rotate, so that the lifting of the straight bar 46a is not hindered.

Further, referring to fig. 10 to 12, the structure of the guide 60 on the lifting and rotating device of the present embodiment includes a base plate 61 parallel to the straight rod 46a corresponding to the guide 60, two bolts 62 perpendicular to the base plate 61 and spaced apart from each other are disposed on the base plate 61, a transverse bearing 63 is respectively mounted on the two bolts 62, and the straight rod 46a is fittingly clamped between the two transverse bearings 63; the base plate 61 is provided with a notch 611 corresponding to the position of the straight rod 46a, the notch 611 is provided with a vertical bearing 64, the outer peripheral wall of which abuts against the straight rod 46a, the vertical bearing 64 is sleeved on a pin shaft 55 perpendicular to the straight rod 46a, and the pin shaft 55 is fixed with the base plate 61. The base plate 61 is fixed to one of the upper fixing plate 44a and the lift driving plate 42a which is slidable with respect to the straight rod 46 a; that is, when the straight bar 46a is provided in the first mode, the substrate 61 is fixed to the elevating drive plate 42 a; when the straight bar 46a is provided in the second manner as described above, the base plate 61 is fixed to the upper fixing plate 44 a. It should be noted that in this embodiment, the substrate 61 of the guide 60 is only used as a mounting carrier for three bearings, and this embodiment is a preferred substrate 61 as a mounting carrier, and the positions of the three bearings relative to the straight rod 46a are described, and in other embodiments, the mounting carrier is not limited to a plate shape, but may also be a block shape or an irregular shape, and the mounting carrier does not necessarily need to be parallel to the straight rod 46a.

In this embodiment, the base plate 61 is fixed on the upper fixing plate 44a, the straight rod 46a is adapted to be clamped in a concave area surrounded by two lateral bearings 63 and a vertical bearing 64, so that three sides of the straight rod 46a are abutted and limited by the bearings, and the function is equivalent to the above-mentioned connecting shaft sleeve Z, thereby preventing the deviation of the straight rod 46a, and making the sliding of the straight rod 46a relative to the upper fixing plate 44a more stable, and because the lateral bearings 63 and the vertical bearings 64 are abutted with the straight rod 46a in a tangential manner, when the straight rod 46a slides relative to the upper fixing plate 44a, the lateral bearings 63 and the vertical bearings 64 rotate around their axes, thereby greatly reducing the friction resistance when the straight rod 46a moves, and making the straight rod 46a still slide very easily and smoothly.

Specifically, a groove (not shown) for accommodating the pin shaft 55 is further formed in the substrate 61, the pin shaft 55 is accommodated in the groove, the two ends of the pin shaft 55 are pressed and fixed in the groove through the fastening pieces 66, and the pin shaft 55 is arranged in the groove, so that the axis of the vertical bearing 64 is more stable, and the offset cannot be generated.

With further specific reference to fig. 10 and 13, in the present embodiment, the transmission member between the driving member 41a and the lead screw 43a includes a driving gear 54 and a driven gear 55 engaged with each other, wherein the driving gear 54 is mounted on the output end of the motor, and the driven gear 55 is mounted on the end of the lead screw 43 a. The rotation speed ratio of the driving member 41a to the screw 43a can also be adjusted by selecting different sizes of the driving gear 54 and the driven gear 55. Further, at least one driven gear 57 is provided in parallel between the drive gear 54 and the driven gear 54, and the drive gear 54, the transmission gear 57, and the driven gear 55 are sequentially engaged with each other. Specifically, in the present embodiment, the driving gear 54 and each driven gear 55 are respectively mounted on a base 56 through a bearing member 59, so that the driving gear 54 and the driven gear 55 are kept fixed in position, and the fixed connection between the driving end of the driving member 41a and the driving gear 54 and the fixed connection between the lead screw 43a and the driven gear 55 can be fixed in the radial direction through a pin; the base 56 is also provided with a protective shield 58 at each end thereof for blocking the gear row at each end thereof.

Further, when the lifting and rotating device of the two embodiments of the present invention is used in a virus inactivation monitor apparatus, the top end of the lifting structure is used for installing the blood bag storage device 30, and a blood bag suspension plate device is correspondingly installed above the spindle 10 (in the attached figures of this embodiment, structural technicians of the blood bag suspension plate may refer to the structural description of the weighing disk and the hook in patent No. 201520357286.9, which is not described herein again), so as to meet the operation requirement of virus inactivation. Referring to fig. 5 and fig. 8 in particular, in the present embodiment, the accommodating device 30 includes a supporting chassis 31 sleeved on the main shaft 10 and an accommodating box 32 arranged on the supporting chassis 31, and the supporting chassis 31 is fixed to the sliding sleeve 20; the storage case 32 has accommodating portions 321 corresponding to hooks on the blood bag hanging plate, each accommodating portion 321 being for accommodating one collected blood bag, respectively; namely, the blood bag hung on the hook corresponds to the blood bag in the corresponding accommodating part 321; the storage box 32 and the support chassis 31 may be integrally or separately provided. In this embodiment, the portion 321 that holds of receiver 32 adopts and is the circumference around main shaft 10 and distributes to saved storage device 30's occupation space by a wide margin, and adopted couple and the mode of the portion 321 position one-to-one that holds, so, made things convenient for hanging and monitoring of blood bag more, the monitoring management that makes each blood bag is more convenient, is difficult for makeing mistakes.

Because this embodiment has the plasma virus inactivation monitor of the lift rotary device of above-mentioned structure, carrying out the plasma virus inactivation in-process, to different processing steps, accessible lift actuating mechanism 40 drive sliding sleeve 20 goes up and down to adjust storage device 30's height, so that storage device 30's height and current pipe length cooperation, and then methylene blue's the operation of adding and filtering operation all can accomplish on this plasma virus inactivation monitor, make the monitoring of plasma virus inactivation operation more convenient, simple.

Furthermore, the storage box 32 of this embodiment is further provided with a turntable base 33 sleeved on the main shaft 10, the turntable base 33 is fixed to the top end of the sliding sleeve 20, and a plurality of rotating handles 34 distributed along the radial direction of the main shaft 10 are distributed at intervals on the outer edge of the turntable base 33, so that the rotating handles 34 are indirectly connected with the main shaft 10. Rotate carousel seat 33 through operation turning handle 34, rotate sliding sleeve 20 promptly, then sliding sleeve 20 takes lift driving plate 42 to rotate, because lift driving plate 42 and lead screw 43, lead screw 43 is owing to be connected with main shaft 10 through upper fixed plate 44, bottom plate 45 and support curb plate 47, consequently whole lift rotary device 200 homogeneous phase rotates frame 100, the blood bag hangs the board and rotates with receiver 32 synchronization, so, at hanging blood bag and follow-up inspection in-process, need not to stir the blood bag repeatedly, only need rotate handle 34 with rotating main shaft 10 through the operation, and then find the couple that corresponds and carry out the blood bag and hang or find corresponding blood bag and inspect, make the hanging of blood bag and inspect the operation more convenient like this. Specifically, the twist grip 34 of this embodiment includes a ball-shaped handle (not numbered) and a connecting rod (not numbered), and the ball-shaped handle is connected in the one end of connecting rod, and the other end spiro union of connecting rod is on the carousel seat 33, and the ball-shaped handle makes twist grip 34 better grip, and it is more convenient to the rotation operation of carousel seat 33.

In addition, the rotating handle 34 can be arranged in another way, that is, the rotating handle 34 is directly connected with the main shaft 10, so that the main shaft 10 can be directly rotated by operating the rotating handle 34 to rotate, the whole lifting and rotating device 200 can rotate along with the main shaft, and the hanging and subsequent inspection operations of the blood bag are also more convenient. Of course, the rotating handle 34 with this arrangement needs to be kept away from the ascending and descending movement path of the storage box 32, and the rotating handle 34 can be connected to the main shaft 10 at a position higher than the highest point of the storage box 32.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims

1. The utility model provides a plasma virus inactivation monitor, includes the frame, its characterized in that, plasma virus inactivation monitor still includes lift rotary device:

the lifting and rotating device comprises a vertically arranged main shaft, a lifting mechanism lifting along the axial direction of the main shaft and a lifting driving mechanism for driving the lifting mechanism to lift;

the lifting driving mechanism comprises an upper fixing plate and a lower fixing plate which are horizontally and fixedly arranged on the main shaft, and a vertically arranged supporting side plate is fixedly arranged between the upper fixing plate and the lower fixing plate; a lifting driving plate horizontally arranged and a lead screw vertically arranged are arranged between the upper fixing plate and the lower fixing plate;

the lifting driving mechanism further comprises a driving piece for driving the screw rod to rotate, the driving piece is fixed on the upper fixing plate, the top end of the screw rod is connected with the output end of the driving piece, and the bottom end of the screw rod can rotate around the axis of the screw rod and is limited on the lower fixing plate;

the screw rod is connected with the lifting driving plate through a nut, the driving piece drives the screw rod to rotate, and the lifting driving plate is driven to move up and down between the upper fixing plate and the lower fixing plate through the nut;

an optical coupling sensor for detecting the height of the lifting driving plate is mounted on the supporting side plates, or an optical coupling sensing sheet is arranged on the lifting driving plate, and a sensing seat corresponding to the optical coupling sensing sheet is arranged on one supporting side plate;

the upper end and the lower end of the main shaft are both provided with rotating bearings;

2. The plasma virus inactivation monitor of claim 1, wherein the lifting mechanism comprises a sliding sleeve sleeved on the main shaft, the lower end of the sliding sleeve is fixedly connected with the lifting driving plate, and the upper end of the sliding sleeve penetrates through the upper fixing plate;

3. The monitor for plasma virus inactivation according to claim 1, wherein the driving member is a motor connected to a screw rod through a transmission member; the transmission part comprises a first synchronous belt wheel, a second synchronous belt wheel and a synchronous belt sleeved on the first synchronous belt wheel and the second synchronous belt wheel; wherein,

4. The plasma viral inactivation monitor of claim 3, wherein the transmission further comprises a drive gear and a driven gear in meshing engagement; wherein,

5. The monitor of claim 4, wherein at least one transmission gear is disposed between the driving gear and the driven gear in parallel; the driving gear, the transmission gear and the driven gear are meshed with each other in sequence.

6. The plasma virus inactivation monitor of claim 1, wherein a vertically disposed lifting guide bar is disposed between the upper fixing plate and the lower fixing plate;

7. The plasma viral inactivation monitor of claim 2, wherein the lifting mechanism further comprises a guide member disposed between the straight rod and the upper fixation plate;

8. The monitor of claim 1 or 2, wherein the main shaft is further provided with at least one rotating handle directly or indirectly.