CN106490365A - A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease - Google Patents

A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease Download PDF

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Publication number
CN106490365A
CN106490365A CN201610963536.2A CN201610963536A CN106490365A CN 106490365 A CN106490365 A CN 106490365A CN 201610963536 A CN201610963536 A CN 201610963536A CN 106490365 A CN106490365 A CN 106490365A
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parts
radix
chinese herbal
feed additive
barren sow
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CN106490365B (en
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应朝阳
黄秀声
林忠宁
陆烝
李振武
杨有泉
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Institute of Agricultural Ecology of Fujian Academy of Agricultural Sciences
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Institute of Agricultural Ecology of Fujian Academy of Agricultural Sciences
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/02Breeding vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

Abstract

The invention belongs to barren sow field of feed, is more particularly to a kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease and preparation method thereof.The preparation method includes:By Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae successively with 60% 90% ethanol, drinking water reflux, extract, united extraction liquid, again flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and the Aqueous extracts of Radix Glycyrrhizae mix, mixed liquor concentration, dry processing and form dry powder, finally mix homogeneously and pack with the Fructus Hordei Germinatus (parched) powder and Thallus Laminariae (Thallus Eckloniae) powder crushed.The Chinese herbal feed additive raw material of the present invention is scientific and reasonable, preparation process is workable, and the additive palatability of preparation is good, can effectively prevent the generation of barren sow digestive tract disease, production performance, anti-stress and the immunity of barren sow is improved, improves the quality and nutritive value of Carnis Sus domestica.

Description

A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease
Technical field
The invention belongs to barren sow field of feed, is more particularly in a kind of prevention and treatment barren sow digestive tract disease Medical herbs feed additive and preparation method thereof.
Background technology
Chinese herbal medicine is natural green plantss, has nutrition and two medicinal attribute concurrently, with promotion animal growth, Improve the function such as efficiency of feed utilization, apply in meat swine rearing, but at present Chinese herbal feed additive mainly for On in terms of the production performance of barren sow, immunity, and it is directed to less in terms of prevention barren sow digestive tract disease, and effect is not bright enough Aobvious;Digestive tract disease is one of swine diseasess for frequently occurring in recent years as suffered from diarrhoea, and the growth for having a strong impact on barren sow is even dead, provisions Grow enterprise or peasant household causes great economic loss, at present, for this little swine diseases mainly using antibiotic therapy, bring comparison tight The medicament residue problem of weight, and such swine diseasess are treated with Chinese herbal medicine, medicament residue problem can be solved very well;Meanwhile, much The inadequate scientific and precise of Chinese herbal feed additive prescription, palatability are poor, and Chinese herbal feed additive mostly is drying, crushing, mixes The powder for closing, processing technology fall behind, and addition is excessive, constrains the popularization and application of barren sow Chinese herbal feed additive.
Content of the invention
It is an object of the invention to provide a kind of prevention and treatment barren sow digestive tract disease Chinese herbal feed additive and its Preparation method, raw material are scientific and reasonable, and preparation process is workable, and the additive palatability of preparation is good, can effectively prevent meat The generation of swine alimentary canal disease, improves production performance, anti-stress and the immunity of barren sow, improves quality and the nutriture value of Carnis Sus domestica Value.
A kind of Chinese herbal feed additive of prevention barren sow digestive tract disease, the raw material components of the additive are according to weight Number includes:Flower of poplar 4-10 parts, Herba Portulacae 4-10 parts, Radix Pulsatillae 4-10 parts, Semen Raphani 4-10 parts, rough Semen Coicis 4-10 parts, Fu Siberian cocklebur 4-10 parts, Cortex Magnoliae Officinalis 2-8 part, Rhizoma Atractylodis Macrocephalae 2-8 parts, Radix Aucklandiae 2-8 parts, Flos Sophorae 2-8 parts, Fructus Chebulae's 2-8 parts, Semen Euryaless 2-8 parts, Radix Astragali 2-6 Part, Radix Codonopsis 2-6 parts, Radix Scutellariae 2-6 parts, Rhizoma Atractylodis 2-6 parts, Fructus Hordei Germinatus (parched) 1-5 parts, Thallus Laminariae (Thallus Eckloniae) 1-5 parts, Fructus Crataegi 1-3 parts, Pericarpium Citri Reticulatae 1-3 parts are sweet Careless 1-3 parts.
The preparation method of Chinese herbal feed additive of the present invention, including:By Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae Successively use 60%-90% ethanol, drinking water reflux, extract, united extraction liquid, then flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, The Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and the Aqueous extracts of Radix Glycyrrhizae mix, mixed liquor concentration, dry plus Work forms dry powder, finally mixs homogeneously and pack with the Fructus Hordei Germinatus (parched) powder and Thallus Laminariae (Thallus Eckloniae) powder crushed.
Comprise the following steps that:
(1), crush:Fructus Hordei Germinatus (parched) and Thallus Laminariae (Thallus Eckloniae) are crushed, the screen cloth of 80-160 mesh is crossed, standby;
(2), extraction:Mass concentration by Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae 4-8 times of bulking value of medicine is 60%-90% alcohol reflux 0.5-1.5 hours, collect ethanol extract a, then again with the drink of 4-8 times of bulking value of medicine With water backflow extraction 2-3 time, temperature 85-95 DEG C, each 0.5-1.5 hours collect extracting solution b;By flower of poplar, Herba Portulacae, white Head father-in-law, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and Radix Glycyrrhizae addition 4-8 times of medicine weigh The drinking water of amount volume is decocted 2-3 time, each 0.5-1.5 hours, and temperature 85-95 DEG C collects extracting solution c;
(3), concentration:By step extracting solution a, b and c mixing (2), when being concentrated into 40-60 DEG C, relative density is 1.05-1.10's Concentrated solution;
(4), be spray-dried:The dextrin for accounting for that concentrated solution weight ratio is 1%-3% is added, is stirred and is spray-dried;
(5), prepare:It is that 0.02-0.05%CMC and weight ratio are 0.03- to add weight ratio in dry powder toward after being spray-dried 0.05% phospholipid, mix homogeneously;
(6), sieve:Cross 80-160 eye mesh screens;
(7), mixing:By step(6)Dry powder and step after sieving(1)The Fructus Hordei Germinatus (parched) powder for obtaining and Thallus Laminariae (Thallus Eckloniae) powder mix homogeneously, bag Dress.
The present invention Chinese herbal feed additive application be:By the additive by the weight ratio of barren sow feedstuff feed amount it is The ratio of 0.1-0.5% is added to the daily feedstuff of barren sow(Powder)In, feed is carried out after mixing thoroughly, it is also possible to which premix material form adds Being added to and pellet being a granulated in barren sow basal diet formula and carry out feed, the Chinese herbal feed additive is from the beginning of barren sow 40kg Carry out overall process uninterruptedly to add.
The present invention remarkable advantage be:
(1), the present invention preparation method take extraction, concentration with spray method, the " micro of feed additive can have been accomplished Change, high efficiency ", convenient production, transport and feed, the demand of adaptation modern times barren sow large-scale cultivation, while to Semen Raphani, the rough heart of a lotus seed Leach extraction method of the medical materials such as rice, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae using first alcohol extraction water extraction again, it is ensured that the liposoluble constituent of these medical materials with Water soluble ingredient is leached out together, ensures effect of Chinese herbal feed additive to greatest extent.
(2), the present invention Chinese herbal feed additive scientific formula, coordinate rationally, the Chinese herbal feed additive prescription Middle flower of poplar, Herba Portulacae, the Radix Pulsatillae, Fructus Chebulae and Semen Euryaless are respectively provided with different degrees of heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping and removing dampness to be stopped The effects such as rushing down, synergistic application have the good prophylactic treatment such as gi system disease such as dysentery, diarrhoea, and fine antiinflammatory is antibacterial disease-resistant Toxic action;Semen Raphani, Cortex Magnoliae Officinalis, the Radix Aucklandiae, Thallus Laminariae (Thallus Eckloniae), Fructus Hordei Germinatus (parched) and Fructus Crataegi be respectively provided with different degrees of circulation of qi promoting, help digestion, de-swelling, change , there are the various symptoms that treatment gi system disease causes well stagnant the effects such as, synergistic application;Rough Semen Coicis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Huang The effects such as a kind of reed mentioned in ancient books, Rhizoma Atractylodis, Fructus Hordei Germinatus (parched) and Pericarpium Citri Reticulatae etc. are respectively provided with different degrees of spleen benefiting and stimulating the appetite, eliminate dampness and have diuretic effect, synergistic application has very The various symptoms that good prevention and alleviation gi system disease cause;The Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Thallus Laminariae (Thallus Eckloniae), Fructus Hordei Germinatus (parched), Pericarpium Citri Reticulatae, mountain Short, bristly hair or beard and Radix Glycyrrhizae are respectively provided with effect of different degrees of invigorating the spleen and replenishing QI, calming heart and tranquilizing mind, and synergistic application has fine growth promotion, resisting should The sharp, effect of enhance immunity.
(3), the present invention have obvious preventive effect, Incidence of Diarrhea to compare matched group to barren sow digestive tract disease(Routine is not Add medicine)Reduce 41.9%-85.0%;Be significantly improved effect to the growth performance of barren sow and immunity, with matched group Compare, wherein feedstuff-meat ratio reduces 12..0%-23.3%, the content of barren sow Immunoglobulin in Serum IgA improves 14.5%-23.4%, The content of Immunoglobulin IgM improves 9.7%-18.6%, and the content of immunoglobulin IgG improves 10.2%-14.3%;Meanwhile, right Meat quality also has improvement result, and compared with matched group, wherein eye muscle area improves 10.0%-19.6%, and cooked meat percentage improves 5.8%- 8.7%th, total amino acidss content improves 8.5%-12.3%, intramuscular fat acid content and improves 15.2%-23.5%.
(4), the present invention have obvious therapeutical effect to barren sow digestive tract disease, treatment total effective rate reaches 78.5%-91.0%, With Western medicine group(Amoxicillin+amikacin+gentamycin sulfate+multidimensional)It is close to, while treatment, piglet can also be improved Growth performance, improve meat quality, compared with Western medicine group, feedstuff-meat ratio reduce 7.0%-13.27%, eye muscle area improve 8.5%- 13.0%, cooked meat percentage improves 4.5%-6.5%, total amino acidss content and improves 8.6%-11.7%, intramuscular fat acid content raising 10.5%- 19.1%.
Specific embodiment
It is below several instantiations of the present invention, further describes the present invention, but the present invention is not limited only to this.
Example 1
A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease, the raw material components of the additive are according to weight Amount number includes:10 parts of flower of poplar, 10 parts of Herba Portulacae, 10 parts of the Radix Pulsatillae, 4 parts of Semen Raphani, 4 parts of rough Semen Coicis, 4 parts of Poria, Cortex Magnoliae Officinalis 8 Part, 8 parts of the Rhizoma Atractylodis Macrocephalae, 8 parts of the Radix Aucklandiae, 2 parts of Flos Sophorae, 2 parts of Fructus Chebulae, 2 parts of Semen Euryaless, 6 parts of the Radix Astragali, 6 parts of Radix Codonopsis, 2 parts of Radix Scutellariae, 2 parts of Rhizoma Atractylodis are fried 5 parts of Fructus Hordei Germinatus, 1 part of Thallus Laminariae (Thallus Eckloniae), 1 part of Fructus Crataegi, 2 parts of Pericarpium Citri Reticulatae, 3 parts of Radix Glycyrrhizae.(Total 100 parts)
The preparation method of Chinese herbal feed additive, comprises the following steps that:
(1)Crush:Fructus Hordei Germinatus (parched) and Thallus Laminariae (Thallus Eckloniae) are crushed, the screen cloth of 80 mesh is crossed, standby;
(2)Extraction:It is 60% second by the mass concentration of 8 times of Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae medicine bulking value Alcohol reflux is extracted 1.5 hours, collects ethanol extract a, is then extracted 2 times with the drinking water backflow of 8 times of medicine bulking value again, 85 DEG C of temperature, 1.5 hours every time, collects extracting solution b;By flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and Radix Glycyrrhizae add the drinking water of 4 times of drug weight volume to decoct 2 times, every time 1.5 hours, 85 DEG C of temperature collected extracting solution c;
(3)Concentration:By step(2)Extracting solution a, b and c mixing, when being concentrated into 40 DEG C, relative density is 1.05 concentrated solution;
(4)It is spray-dried:Add in concentrated solution and account for the dextrin that concentrated solution weight ratio is 1%, stir and be spray-dried;
(5)Prepare:It is that 0.02%CMC and weight ratio are 0.05% phospholipid, mixing to add weight ratio in dry powder toward after being spray-dried Uniformly;
(6)Sieve:Cross 80 eye mesh screens;
(7)Mixing:By step(6)Dry powder and step after sieving(1)The Fructus Hordei Germinatus (parched) powder for obtaining and Thallus Laminariae (Thallus Eckloniae) powder mix homogeneously, bag Dress.
The application of Chinese herbal feed additive, including:The weight that Chinese herbal feed additive is pressed barren sow feedstuff feed amount Ratio than 0.1% is added in the daily feedstuff of barren sow, carries out feed after mixing thoroughly, and the Chinese herbal feed additive is from barren sow 40kg comes into effect overall process uninterruptedly to be added.
Example 2
A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease, the raw material components of the additive are according to weight Amount number includes:7 parts of flower of poplar, 7 parts of Herba Portulacae, 7 parts of the Radix Pulsatillae, 7 parts of Semen Raphani, 7 parts of rough Semen Coicis, 7 parts of Poria, 5 parts of Cortex Magnoliae Officinalis, 5 parts of the Rhizoma Atractylodis Macrocephalae, 5 parts of the Radix Aucklandiae, 5 parts of Flos Sophorae, 5 parts of Fructus Chebulae, 5 parts of Semen Euryaless, 4 parts of the Radix Astragali, 4 parts of Radix Codonopsis, 4 parts of Radix Scutellariae, 4 parts of Rhizoma Atractylodis, cooked wheat 3 parts of bud, 3 parts of Thallus Laminariae (Thallus Eckloniae), 3 parts of Fructus Crataegi, 1 part of Pericarpium Citri Reticulatae, 2 parts of Radix Glycyrrhizae.(Total 100 parts)
The preparation method of Chinese herbal feed additive, comprises the following steps that:
(1)Crush:Fructus Hordei Germinatus (parched) and Thallus Laminariae (Thallus Eckloniae) are crushed, the screen cloth of 120 mesh is crossed, standby;
(2)Extraction:It is 80% second by the mass concentration of 6 times of Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae medicine bulking value Alcohol reflux is extracted 1.0 hours, collects ethanol extract a, is then extracted 2 times with the drinking water backflow of 6 times of medicine bulking value again, 90 DEG C of temperature, 1.0 hours every time, collects extracting solution b;By flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and Radix Glycyrrhizae add the drinking water of 6 times of drug weight volume to decoct 2 times, every time 1.0 hours, 90 DEG C of temperature collected extracting solution c;
(3)Concentration:By step(2)Extracting solution a, b and c mixing, when being concentrated into 50 DEG C, relative density is 1.05 concentrated solution;
(4)It is spray-dried:Add in concentrated solution and account for the dextrin that concentrated solution weight ratio is 2%, stir and be spray-dried;
(5)Prepare:It is that 0.03%CMC and weight ratio are 0.04% phospholipid, mixing to add weight ratio in dry powder toward after being spray-dried Uniformly;
(6)Sieve:Cross 120 eye mesh screens;
(7)Mixing:By step(6)Dry powder and step after sieving(1)The Fructus Hordei Germinatus (parched) powder for obtaining and Thallus Laminariae (Thallus Eckloniae) powder mix homogeneously, bag Dress.
The application of Chinese herbal feed additive, including:Chinese herbal feed additive is added to barren sow base with premix material form Being a granulated into pellet in plinth Diet Formula carries out feed, and the addition of Chinese herbal feed additive accounts for weight and compares 0.3%, in this Medical herbs feed additive comes into effect overall process from barren sow 40kg uninterruptedly to be added.
Example 3
A kind of Chinese herbal feed additive of prevention and treatment barren sow digestive tract disease, the raw material components of the additive are according to weight Amount number includes:4 parts of flower of poplar, 4 parts of Herba Portulacae, 4 parts of the Radix Pulsatillae, 10 parts of Semen Raphani, 10 parts of rough Semen Coicis, 10 parts of Poria, Cortex Magnoliae Officinalis 2 Part, 2 parts of the Rhizoma Atractylodis Macrocephalae, 2 parts of the Radix Aucklandiae, 8 parts of Flos Sophorae, 8 parts of Fructus Chebulae, 8 parts of Semen Euryaless, 2 parts of the Radix Astragali, 2 parts of Radix Codonopsis, 6 parts of Radix Scutellariae, 6 parts of Rhizoma Atractylodis are fried 1 part of Fructus Hordei Germinatus, 5 parts of Thallus Laminariae (Thallus Eckloniae), 2 parts of Fructus Crataegi, 3 parts of Pericarpium Citri Reticulatae, 1 part of Radix Glycyrrhizae.(Total 100 parts)
The preparation method of Chinese herbal feed additive, comprises the following steps that:
(1)Crush:Fructus Hordei Germinatus (parched) and Thallus Laminariae (Thallus Eckloniae) are crushed, the screen cloth of 160 mesh is crossed, standby;
(2)Extraction:It is 90% second by the mass concentration of 4 times of Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae medicine bulking value Alcohol reflux is extracted 0.5 hour, collects ethanol extract a, is then extracted 3 times with the drinking water backflow of 4 times of medicine bulking value again, 95 DEG C of temperature, 0.5 hour every time, collects extracting solution b;By flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with and Radix Glycyrrhizae add the drinking water of 8 times of drug weight volume to decoct 3 times, every time 0.5 hour, 95 DEG C of temperature collected extracting solution c;
(3)Concentration:By step(2)Extracting solution a, b and c mixing, when being concentrated into 60 DEG C, relative density is 1.10 concentrated solution;
(4)It is spray-dried:Add in concentrated solution and account for the dextrin that concentrated solution weight ratio is 3%, stir and be spray-dried;
(5)Prepare:It is that 0.05%CMC and weight ratio are 0.03% phospholipid, mixing to add weight ratio in dry powder toward after being spray-dried Uniformly;
(6)Sieve:Cross 160 eye mesh screens;
(7)Mixing:By step(6)Dry powder and step after sieving(1)The Fructus Hordei Germinatus (parched) powder for obtaining and Thallus Laminariae (Thallus Eckloniae) powder mix homogeneously, bag Dress.
The application of Chinese herbal feed additive, the application include:By Chinese herbal medicine additive by barren sow feedstuff feed amount Ratio of the weight than 0.5% is added in the daily feedstuff of barren sow, carries out feed after mixing thoroughly, and the Chinese herbal feed additive is from meat Pig 40kg comes into effect overall process uninterruptedly to be added.
The present invention is embodied as effect
The present invention has obvious preventive effect, Incidence of Diarrhea to compare matched group to barren sow digestive tract disease(Routine is without medicine) Reduce 41.9%-85.0%;Be significantly improved effect to the growth performance of barren sow and immunity, compared with matched group, wherein Feedstuff-meat ratio reduces 12..0%-23.3%, and the content of barren sow Immunoglobulin in Serum IgA improves 14.5%-23.4%, immune globulin The content of white IgM improves 9.7%-18.6%, and the content of immunoglobulin IgG improves 10.2%-14.3%;Meanwhile, to meat quality Also there is improvement result, compared with matched group, wherein eye muscle area improves 10.0%-19.6%, cooked meat percentage improves 5.8%-8.7%, total Amino acid content improves 8.5%-12.3%, intramuscular fat acid content and improves 15.2%-23.5%.
The present invention has obvious therapeutical effect to barren sow digestive tract disease, and treatment total effective rate reaches 78.5%-91.0%, with west Medicine group(Amoxicillin+amikacin+gentamycin sulfate+multidimensional)It is close to, while treatment, the life of piglet can also be improved Long performance, improves meat quality, and compared with Western medicine group, feedstuff-meat ratio reduces 7.0%-13.27%, and eye muscle area improves 8.5%- 13.0%, cooked meat percentage improves 4.5%-6.5%, total amino acidss content and improves 8.6%-11.7%, intramuscular fat acid content raising 10.5%- 19.1%.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes that is done according to scope of the present invention patent with Modification, should all belong to the covering scope of the present invention.

Claims (4)

1. a kind of prevention and treatment barren sow digestive tract disease Chinese herbal feed additive, it is characterised in that:The additive Raw material components include according to parts by weight:Flower of poplar 4-10 parts, Herba Portulacae 4-10 parts, Radix Pulsatillae 4-10 parts, Semen Raphani 4-10 parts, Rough Semen Coicis 4-10 parts, Poria 4-10 parts, Cortex Magnoliae Officinalis 2-8 part, Rhizoma Atractylodis Macrocephalae 2-8 parts, Radix Aucklandiae 2-8 parts, Flos Sophorae 2-8 parts, Fructus Chebulae's 2-8 parts, Gorgon euryale Real 2-8 parts, Radix Astragali 2-6 parts, Radix Codonopsis 2-6 parts, Radix Scutellariae 2-6 parts, Rhizoma Atractylodis 2-6 parts, Fructus Hordei Germinatus (parched) 1-5 parts, Thallus Laminariae (Thallus Eckloniae) 1-5 parts, Fructus Crataegi 1-3 Part, Pericarpium Citri Reticulatae 1-3 parts, Radix Glycyrrhizae 1-3 parts.
2. a kind of preparation method of Chinese herbal feed additive as claimed in claim 1, it is characterised in that:The preparation method Including:Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae are used 60%-90% ethanol, drinking water reflux, extract, united extraction successively Liquid, then flower of poplar, Herba Portulacae, the Radix Pulsatillae, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi with Mix with the Aqueous extracts of Radix Glycyrrhizae, mixed liquor concentration, dry processing and form dry powder, finally mixed with the Fructus Hordei Germinatus (parched) powder and Thallus Laminariae (Thallus Eckloniae) powder that crushes Close uniform and pack.
3. the preparation method of Chinese herbal feed additive according to claim 2, it is characterised in that:Comprise the following steps that:
(1)Crush:Fructus Hordei Germinatus (parched) and Thallus Laminariae (Thallus Eckloniae) are crushed, the screen cloth of 80-160 mesh is crossed, standby;
(2)Extraction:Mass concentration by Semen Raphani, rough Semen Coicis, the Radix Aucklandiae, Fructus Chebulae and Pericarpium Citri Reticulatae medicine bulking value 4-8 times is 60%-90% alcohol reflux 0.5-1.5 hours, collect ethanol extract a, then again with the drink of medicine bulking value 4-8 times With water backflow extraction 2-3 time, temperature 85-95 DEG C, each 0.5-1.5 hours collect extracting solution b;By flower of poplar, Herba Portulacae, white Head father-in-law, Poria, Cortex Magnoliae Officinalis, the Rhizoma Atractylodis Macrocephalae, Flos Sophorae, Semen Euryaless, the Radix Astragali, Radix Codonopsis, Radix Scutellariae, Rhizoma Atractylodis, Fructus Crataegi and and Radix Glycyrrhizae addition drug weight body The drinking water of 4-8 times of product is decocted 2-3 time, each 0.5-1.5 hours, temperature 85-95 DEG C, collects extracting solution c;
(3)Concentration:By step(2)Extracting solution a, b and c mixing, when being concentrated into 40-60 DEG C, relative density is for 1.05-1.10 Concentrated solution;
(4)It is spray-dried:The dextrin for accounting for that concentrated solution weight ratio is 1%-3% is added in concentrated solution, and stirring carries out spray dried Dry;
(5)Prepare:It is that 0.02-0.05%CMC and weight ratio are 0.03-0.05% to add weight ratio in dry powder toward after being spray-dried Phospholipid, mix homogeneously;
(6)Sieve:Cross 80-160 eye mesh screens;
(7)Mixing:By step(6)Dry powder and step after sieving(1)The Fructus Hordei Germinatus (parched) powder for obtaining and Thallus Laminariae (Thallus Eckloniae) powder mix homogeneously, bag Dress.
4. a kind of application of Chinese herbal feed additive as claimed in claim 1, it is characterised in that:The application includes:Will Chinese herbal feed additive is added in the daily feedstuff of barren sow in the ratio of the weight than 0.1-0.5% of barren sow feedstuff feed amount, Feed is carried out after mixing thoroughly;Or be added in barren sow basal diet formula with premix material form be a granulated into pellet carry out feed Raise, the Chinese herbal feed additive comes into effect overall process from barren sow 40kg uninterruptedly to be added.
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CN107568482A (en) * 2017-10-17 2018-01-12 肖秋花 It is a kind of to improve pork lean meat percentage and the green feed additive of edible quality
CN107594179A (en) * 2017-11-07 2018-01-19 广州美豆生物技术有限公司 A kind of modified form of combination expanded soybean and emulsifying agent easily absorbs feed and preparation method thereof
CN108785368A (en) * 2018-08-29 2018-11-13 江苏食品药品职业技术学院 Treat " four wormwood artemisias " feed addictive and the preparation method and application thereof of grice diarrhoea
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CN113229400A (en) * 2021-06-11 2021-08-10 福建省农业科学院农业生态研究所 Preparation method of Chinese herbal medicine feed additive for piglets

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