CN106474218A - Fructus Chaenomelis ferment nutritional solution and preparation method thereof - Google Patents

Fructus Chaenomelis ferment nutritional solution and preparation method thereof Download PDF

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Publication number
CN106474218A
CN106474218A CN201610955704.3A CN201610955704A CN106474218A CN 106474218 A CN106474218 A CN 106474218A CN 201610955704 A CN201610955704 A CN 201610955704A CN 106474218 A CN106474218 A CN 106474218A
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parts
folium crataegi
fructus
preparation
water
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金凤章
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GUANGXI JIN CHEN TECHNOLOGY Co Ltd
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GUANGXI JIN CHEN TECHNOLOGY Co Ltd
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Priority to CN201610955704.3A priority Critical patent/CN106474218A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of Fructus Chaenomelis ferment nutritional solution and preparation method thereof, it is related to enzyme nutrient solution technical field.This Fructus Chaenomelis ferment nutritional solution is made up of Fructus Chaenomeliss, dry Folium Crataegi, Mel, oligosaccharide, glucose powder, dry yeast and water by fermentation, and preparation method is by by Fructus Chaenomeliss pulping, will be to boil water for dry Folium Crataegi, add Mel, oligosaccharide, dry yeast fermentation and make.The present invention has remarkable result to preventing and treating endocrine disturbance and has no side effect after taking.

Description

Fructus Chaenomelis ferment nutritional solution and preparation method thereof
Technical field
The present invention relates to enzyme nutrient solution technical field, especially a kind of use Fructus Chaenomeliss are as the Fructus Chaenomeliss ferment of dominant fermentation raw material Plain nutritional solution and preparation method thereof.
Background technology
The various hormones that the hormonal system of human body is secreted under normal circumstances are to maintain balance, such as because certain reason makes This balance is broken(Certain hormonosis or very few), will result in endocrine regulation, cause sterility and infertility, gynaecopathia, Impact beauty treatment, generation is short-tempered, irritability, temper degenerate, hypophysis pathological changes, hypothyroidism, thyroid function are high Enter, Ke's Cotard, diabetes, reduce the harm such as human immunity.These harm impacts to health are very great, once This disease there is, not only treatment time length and medical expense is higher, will bring to patient that serious body and mind injures and economy is born Load.
From the point of view of from the traditional Chinese medical science, endocrine regulation is the performance of the deficiency of YIN, is that congestion is detained body caused by QI and blood is retarded by silt Interior, venation is obstructed, outer poison invasion human body, lochiostasises etc. all may be led to that QI and blood is retarded by silt.So, can be from ordinary times Diet aspect prevents and treats endocrine regulation.But the health product price of the prevention endocrine regulation publicizing in the market is held high Expensive and there is certain potential safety hazard, meanwhile, effect is not also notable.
Content of the invention
The technical problem to be solved be a kind of clothes are provided after have no side effect, treatment endocrine disturbance is had aobvious Write Fructus Chaenomelis ferment nutritional solution of effect and preparation method thereof.
In order to solve the above problems, the technical solution adopted in the present invention is:This Fructus Chaenomelis ferment nutritional solution, using following The raw material of weight portion is made:8~10 parts of Fructus Chaenomeliss, 2~2.5 parts of dry Folium Crataegi, 1~1.5 part of Mel, 1~1.5 part of oligosaccharide, Fructus Vitis viniferae 1 part~1.5 parts of Icing Sugar, 0.1~0.2 part of dry yeast, 120~150 parts of water.
Its preparation method comprises the steps:
(1), Fructus Chaenomeliss are removed the peel, break into papaya puree, standby;
(2), by the water infusion of dry Folium Crataegi, 90-100 part is left in infusion to water, obtains Folium Crataegi solution, by this Folium Crataegi solution It is cooled to 20 DEG C~35 DEG C, standby;
(3), by step(1)Gained papaya puree and step(2)Gained Folium Crataegi solution mixes, and adds Mel, oligosaccharide, dry ferment Mother, loads in container, seals described container, ferment 15~25 days, obtain fermentation liquid;
(4), by step(3)Gained fermentation liquid stratification, filters, obtains final product.
In technique scheme, more specifically technical scheme can also be:Described water is pure water.
Fructus Chaenomeliss of the present invention(Scientific name:Chaenomeles sinensis (Thouin)Koehne):Rosaceae Fructus Chaenomeliss Genus, shrub or dungarunga, produce Shandong, Shaanxi, Hubei, Jiangxi, Anhui, Jiangsu, Zhejiang, Guangdong, Guangxi.Composition is:Fructus Caricae Alkali, papain, chymopapain, lycopene, vitamin B, C, E, sugar, protein, fat, carotene, cryptoxanthine, Violaxanthin, cryptoxanthine ring amide etc., also be rich in oleanolic acid, Fructus Chaenomeliss phenol, Saponin, malic acid, tartaric acid, citric acid, Vitamin C, flavonoid, tannin.It is used as medicine to have and relieve the effect of alcohol, go expectorant, pleasant, dysentery relieving, antitumor, antibacterial and parasiticide effect, strengthen The effect of the effects such as the resistances against diseases of body, spasmolytic.
Folium Crataegi of the present invention, Chinese medicine name.For rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge.var.major N.E.Br. or the dried leaves of Folium Crataegi Grataegus pinnati fida Bge..Summer, season in autumn two adopt Receive, dry.It is distributed in the ground such as northeast, North China.There is blood circulation promoting and blood stasis dispelling, qi-regulating is promoted blood circulation, change effect of turbid lipid-loweringing.For stagnation of QI blood The stasis of blood, obstruction of qi in the chest and cardialgia, chest distress, palpitation and amnesia, vertigo and tinnitus, hyperlipemia.
Due to employing technique scheme, the present invention compared with prior art has the advantages that:
Preparation is simple, because this nutritional solution is to be formed using pure plant-fermented, using safety, has no side effect after clothes;Through clinic Test shows, using this Fructus Chaenomelis ferment nutritional solution, treats endocrine disturbance, short treating period, prevention is notable with curative effect, is difficult multiple Send out.
Specific embodiment
Below in conjunction with specific embodiment, the invention will be further described:
Embodiment one:
The Fructus Chaenomelis ferment nutritional solution of the present embodiment, the raw material using following weight is made:4 kilograms of Fructus Chaenomeliss, 1 kilogram of dry Folium Crataegi, 0.5 kilogram of Mel, 0.5 kilogram of oligosaccharide, 0.5 kilogram of glucose powder, 0.05 kilogram of dry yeast, 60 kilograms of pure water.
The preparation method of this Fructus Chaenomelis ferment nutritional solution comprises the steps:
(1), Fructus Chaenomeliss are removed the peel stripping and slicing, break into papaya puree, standby;
(2), by the water infusion of dry Folium Crataegi, infusion to water is left 45 kilograms, obtains Folium Crataegi solution, will be cold for this Folium Crataegi solution But to 20 DEG C, standby;
(3), by step(1)Gained papaya puree and step(2)Gained Folium Crataegi solution mixes, and adds Mel, oligosaccharide, dry ferment Mother, loads in container, seals described container, ferment 15 days, obtain fermentation liquid;
(4), by step(3)Gained fermentation liquid stratification, filters, obtains final product.
Embodiment 2
The Fructus Chaenomelis ferment nutritional solution of the present embodiment, the raw material using following weight is made:5 kilograms of Fructus Chaenomeliss, dry Folium Crataegi 1.25 thousand Gram, 0.75 kilogram of Mel, 0.75 kilogram of oligosaccharide, 0.75 kilogram of glucose powder, 0.1 kilogram of dry yeast, 75 kilograms of pure water.
The preparation method of this Fructus Chaenomelis ferment nutritional solution comprises the steps:
(1), Fructus Chaenomeliss are removed the peel stripping and slicing, break into papaya puree, standby;
(2), by the water infusion of dry Folium Crataegi, infusion to water is left 50 kilograms, obtains Folium Crataegi solution, will be cold for this Folium Crataegi solution But to 35 DEG C, standby;
(3), by step(1)Gained papaya puree and step(2)Gained Folium Crataegi solution mixes, and adds Mel, oligosaccharide, glucose Powder, dry yeast, load in container, seal described container, ferment 25 days, obtain fermentation liquid;
(4), by step(3)Gained fermentation liquid stratification, filters, obtains final product.
It is below clinical experiment part:
1. test total case load and be 150, the age is 35~55 years old, and all cases are all diagnosed as endocrine disturbance.By these diseases Example is randomly divided into treatment group A, treatment group B and matched group, and every group 50, three groups in sex, age, course of disease no significant difference.
2. medicament selection:Treatment group A uses the Fructus Chaenomelis ferment nutritional solution of the embodiment of the present invention one, each takes 50 milliliters, Sooner or later 2 times are taken daily;Treatment group B uses the Fructus Chaenomelis ferment nutritional solution of the embodiment of the present invention two, each takes 50 milliliters, early daily Evening takes 2 times;Matched group using being commonly used for treating the medicine of endocrine disturbance, routinely take by medicining mode.10 days courses for the treatment of, All treat 3 courses for the treatment of for three groups.
3. efficacy determination:(1)Recovery from illness:Symptom all disappears;(2)Effective:Total urination time reduces, and sleep quality improves;(3) Effectively:Indefatigability, the mental status is good;(4)Invalid:The state of an illness no takes a turn for the better.
4. experimental therapy result is as follows:
As seen from the above table, Fructus Chaenomelis ferment nutritional solution treatment endocrine disturbance of the present invention, short treating period, evident in efficacy.

Claims (3)

1. a kind of Fructus Chaenomelis ferment nutritional solution is it is characterised in that made using the raw material of following weight portion:8 parts~10 parts of Fructus Chaenomeliss, do 2 parts~2.5 parts of Folium Crataegi, 1 part~1.5 parts of Mel, 1 part~1.5 parts of oligosaccharide, 1 part~1.5 parts of glucose powder, 0.1 part of dry yeast ~0.2 part, 120 parts~150 parts of water.
2. a kind of preparation method of Fructus Chaenomelis ferment nutritional solution it is characterised in that:
Raw material using following weight portion:8 parts~10 parts of Fructus Chaenomeliss, 2 parts~2.5 parts of dry Folium Crataegi, 1 part~1.5 parts of Mel, oligosaccharide 1 part~1.5 parts, 1 part~1.5 parts of glucose powder, 0.1 part~0.2 part of dry yeast, 120 parts~150 parts of water;
Its preparation method comprises the steps:
(1), Fructus Chaenomeliss are removed the peel, break into papaya puree, standby;
(2), by the water infusion of dry Folium Crataegi, infusion to water is left 90 parts~100 parts, obtains Folium Crataegi solution, by this Folium Crataegi Solution is cooled to 20 DEG C~35 DEG C, standby;
(3), by step(1)Gained papaya puree and step(2)Gained Folium Crataegi solution mixes, and adds Mel, oligosaccharide, glucose Powder, dry yeast, load in container, seal described container, ferment 15 days~25 days, obtain fermentation liquid;
(4), by step(3)Gained fermentation liquid stratification, filters, obtains final product.
3. Fructus Chaenomelis ferment nutritional solution according to claim 2 preparation method it is characterised in that:Described water is pure water.
CN201610955704.3A 2016-10-27 2016-10-27 Fructus Chaenomelis ferment nutritional solution and preparation method thereof Pending CN106474218A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110547381A (en) * 2019-10-18 2019-12-10 山西农业大学 Preparation method of papaya enzyme compound beverage
JP2020033273A (en) * 2018-08-27 2020-03-05 株式会社大里インターナショナル Pharmaceutical composition for treating electromagnetic hypersensitivity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020033273A (en) * 2018-08-27 2020-03-05 株式会社大里インターナショナル Pharmaceutical composition for treating electromagnetic hypersensitivity
JP7026387B2 (en) 2018-08-27 2022-02-28 株式会社大里インターナショナル Pharmaceutical composition for treating electromagnetic hypersensitivity
CN110547381A (en) * 2019-10-18 2019-12-10 山西农业大学 Preparation method of papaya enzyme compound beverage

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Application publication date: 20170308