CN106421537A - Traditional Chinese medicinal composition for treating gout and preparation method of traditional Chinese medicinal composition - Google Patents

Traditional Chinese medicinal composition for treating gout and preparation method of traditional Chinese medicinal composition Download PDF

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CN106421537A
CN106421537A CN201611164007.2A CN201611164007A CN106421537A CN 106421537 A CN106421537 A CN 106421537A CN 201611164007 A CN201611164007 A CN 201611164007A CN 106421537 A CN106421537 A CN 106421537A
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gout
traditional chinese
chinese medicinal
medicinal composition
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何云清
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HUOSHAN COUNTY HOSPITAL OF CHINESE MEDICINE
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HUOSHAN COUNTY HOSPITAL OF CHINESE MEDICINE
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Abstract

The invention discloses a traditional Chinese medicinal composition for treating gout. The traditional Chinese medicinal composition comprises, by weight, 9-11 parts of rhizoma atractylodis, 14-16 parts of cortex phellodendri, 28-32 parts of coix seeds, 11-13 parts of papayas, 5-7 parts of indigo naturalis, 14-16 parts of talc, 8-10 parts of rhizoma anemarrhenae, 28-32 parts of caulis spatholobi, 14-16 parts of angelica sinensis, 14-16 parts of red peony roots and 11-13 parts of yam rhizomes. The traditional Chinese medicinal composition for treating the gout has the advantages that overall regulation advantages of the compound traditional Chinese medicine are developed, the synergistic effect can be achieved effectively, the effects of clearing heat, removing dampness, promoting blood circulation and dredging collaterals are realized, and the traditional Chinese medicinal composition has good curative effect and quick action on the gout.

Description

A kind of treat Chinese medicine composition of gout and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines is and in particular to a kind of treat Chinese medicine composition of gout and preparation method thereof.
Background technology
, also known as hyperuricemia, sickness rate is high, cure difficult, recurrent exerbation, belongs to disorders of purine metabolism and causes for gout Metabolic disease.Gout is multiple to be born in middle-aged and elderly people, overweight people and brain worker, and age of onset tends to young in recent years Change, its clinical characters is hyperuricemia and the gouty acute arthritises recurrent exerbation that thus causes, tophaceous deposition, bitterly Wind stone chronic arthritiss and joint deformity etc., with redness and swelling of joints, burning pain, recurrent exerbation, joint motion dumb for main Clinical manifestation.Often involving kidney causes chronic interstitial nephritiss and uric acid kidney stones to be formed.Reason is increased according to uric acid in blood Constitutional and Secondary cases two big class can be divided into.The cause of disease of primary gout is due to congenital purine metabolic disturbance, belongs to Heritability.The cause of disease of secondary gout, can be caused by many reasons such as nephropathy, leukemia, medicine, foods, good In male and menopausal woman.Gout belongs to Chinese medicine " arthromyodynia " category.《Treatise on blood trouble》“:Gout, general numbness and hypoesthesia, extremity pain Bitterly, modern name gout, Gu say arthromyodynia ".
Western medicine currently used for treatment gout mainly has:Colchicine, Phenylbutazone or crovaril, indometacin, ibuprofen (ibvprofen, ibuprofen), piroxicam (piroxicanum), naproxen (naproxen congex), ACTH and prednisone etc..But said medicine can only stablize the state of an illness mostly, gout can not be effected a radical cure;Serious pair also can be caused Effect causes the infringement of hepatic and renal function；Even if Emergent therapy is effectively nor symptom management recurs, and can produce drug resistance Property and repellence, or even occur that leukopenia, cardiac function are impaired, hepatic and renal function is impaired, stimulating intestine and stomach system, regeneration barrier Impenetrability anemia, lead to the complication such as diabetes.Increasing expert thinks：From the organic conception of the traditional Chinese medical science, use Chinese medicine Integral syndrome differentiation treats, the good footpath of another bar for the treatment of gout of can yet be regarded as；Not only the toxic and side effects of Chinese medicine itself greatly reduce , and Western medicine dose can be reduced, overcome and take merely the huge toxic and side effects that Western medicine is brought for a long time.But existing market The Chinese patent medicine of upper treatment gout is few, and curative effect is preferably more a lack of, and patient still can only be by taking toxic and side effects in a large number Larger Western medicine is stablizing the state of an illness.
Content of the invention
The invention discloses a kind of Chinese medicine composition treating gout, this Chinese medicine composition has removing damp-heat, and promoting blood circulation is logical The effect of network, treat gout, good effect, instant effect, toxic and side effects are little.
The technical solution used in the present invention is as follows：
It is characterised in that being made up of following bulk drugs, the weight portion of each component is a kind of Chinese medicine composition treating gout：Grey Art 9-11, Cortex Phellodendri 14-16, Semen Coiciss 28-32, Fructus Chaenomeliss 11-13, Indigo Naturaliss 5-7, Talcum 14-16, Rhizoma Anemarrhenae 8-10, Caulis Spatholobi 28- 32nd, Radix Angelicae Sinensis 14-16, Radix Paeoniae Rubra 14-16, Bi 11-13.
The Chinese medicine composition of described treatment gout it is characterised in that being made up of following bulk drugs, the weight of each component Part it is：Rhizoma Atractylodis 10, Cortex Phellodendri 15, Semen Coiciss 30, Fructus Chaenomeliss 12, Indigo Naturaliss 6, Talcum 15, the Rhizoma Anemarrhenae 9, Caulis Spatholobi 30, Radix Angelicae Sinensis 15, Radix Paeoniae Rubra 15, Bi 12.
The preparation method of the described Chinese medicine composition for the treatment of gout is it is characterised in that comprise the following steps：
（1）Weigh each component raw material by formula proportion；
(2) Semen Coiciss are dried, fragrant vinegar, then carry out micronizing, obtain Semen Coiciss micropowder, standby；
（3）The remaining material medicine dry mixed removing in formula outside Talcum is pulverized, then crosses 60 mesh sieves, add thick in coarse powder The Mel of silty amount 1-2%, 1% Fructus Hordei Germinatus powder, 1% Rhizoma Dioscoreae powder, 150% pure water, prepare culture medium, and go out in 121 DEG C Bacterium 15 min, after cooling, by 1% inoculum concentration inoculating lactobacillus acidophilus, presses 2% inoculum concentration inoculation yeast, is 35-36 DEG C in temperature Under conditions of, ferment 24-36h, after fermentation ends, is dried under the conditions of 50-55 DEG C, obtains the mixed powder that ferments；
（4）To step（3）Obtain fermenting in mixed powder plus 8-10 times amount alcohol reflux 2-3 time, each 4-5h, merge and filter Liquid, obtains fermented extracted liquid, and decompression recycling ethanol obtains fermented extracted thick paste to no alcohol taste；
（5）Medicinal residues after alcohol reflux add and formula in Talcum add the decocting of 8-10 times amount and boil 2-3 time, each 1-1.5h , merge decocting liquid, be concentrated into the extractum that 50-60 DEG C of relative density is 1.1-1.2；
（6）By step（2）The Semen Coiciss micropowder of acquisition, step（4）Fermented extracted thick paste, step（5）The water extracted immersing paste, mixes Close uniformly, be vacuum-packed on request, you can.
Usage and dosage：A day three times, each 3-4g, warm water is taken after mixing it with water, and is within general 10 days a course for the treatment of.
Beneficial effect
The Chinese medicine composition of the treatment gout of the present invention, plays the integrally-regulated advantage of herbal mixture, can effectively play collaborative work With playing the effect of removing damp-heat, promoting blood circulation to remove obstruction in the collateral, treating gout good effect, instant effect.Oral through clinical 325 patients Treatment, total effective rate is 100%, can effectively eliminate local red and swollen heat pain symptom.
Therapeutic effect excellent 85.5%, good 15.4%, no Ineffective Cases.
Specific embodiment
A kind of Chinese medicine composition treating gout, is made up of following bulk drugs, the weight of each component（g）For：
Rhizoma Atractylodis 10, Cortex Phellodendri 15, Semen Coiciss 30, Fructus Chaenomeliss 12, Indigo Naturaliss 6, Talcum 15, the Rhizoma Anemarrhenae 9, Caulis Spatholobi 30, Radix Angelicae Sinensis 15, Radix Paeoniae Rubra 15, Bi 12.
Preparation method：
（1）Weigh each component raw material by formula proportion；
(2) Semen Coiciss are dried, fragrant vinegar, then carry out micronizing, obtain Semen Coiciss micropowder, standby；
（3）The remaining material medicine dry mixed removing in formula outside Talcum is pulverized, then crosses 60 mesh sieves, add thick in coarse powder The Mel of silty amount 1-2%, 1% Fructus Hordei Germinatus powder, 1% Rhizoma Dioscoreae powder, 150% pure water, prepare culture medium, and go out in 121 DEG C Bacterium 15 min, after cooling, by 1% inoculum concentration inoculating lactobacillus acidophilus, presses 2% inoculum concentration inoculation yeast, is 35-36 DEG C in temperature Under conditions of, ferment 24-36h, after fermentation ends, is dried under the conditions of 50-55 DEG C, obtains the mixed powder that ferments；
（4）To step（3）Obtain fermenting in mixed powder plus 8-10 times amount alcohol reflux 2-3 time, each 4-5h, merge and filter Liquid, obtains fermented extracted liquid, and decompression recycling ethanol obtains fermented extracted thick paste to no alcohol taste；
（5）Medicinal residues after alcohol reflux add and formula in Talcum add the decocting of 8-10 times amount and boil 2-3 time, each 1-1.5h , merge decocting liquid, be concentrated into the extractum that 50-60 DEG C of relative density is 1.1-1.2；
（6）By step（2）The Semen Coiciss micropowder of acquisition, step（4）Fermented extracted thick paste, step（5）The water extracted immersing paste, mixes Close uniformly, be vacuum-packed on request, you can.
Usage and dosage：A day three times, each 3-4g, warm water is taken after mixing it with water, and is within general 10 days a course for the treatment of.
Model case
1st, Liu, because of " left foot Metatarsophalangeal joint red and swollen heat pain one week ", outpatient clinic, dialectical for gout（Damp and hot numbness type）, Take the Chinese medicine composition of the present invention, a day three times, each 3g, warm water delivery service, after taking a course for the treatment of, cure.After January Pay a return visit, well.
2nd, Zhang, because of " left foot Metatarsophalangeal joint red and swollen heat pain 3 days, increase a day ", outpatient clinic, dialectical for gout （Damp and hot numbness type）, take the Chinese medicine composition of the present invention, a day three times, each 3g, warm water delivery service, take 2 courses for the treatment of Afterwards, cure.Adjust diet, pay a return visit after January, well.
3rd, Sun, because of " in right sufficient Metatarsophalangeal joint red and swollen heat pain January, increase one week ", outpatient clinic, dialectical for gout （Damp and hot numbness type）, take the Chinese medicine composition of the present invention, a day three times, each 3g, warm water delivery service, take a course for the treatment of Afterwards hence it is evident that taking a turn for the better, after continuing to take 1 course for the treatment of, cure.
4th, Huang, because of " left foot red and swollen heat pain 2 weeks, increase 3 days " outpatient clinic, patient gives moxibustion therapy because of other places, causes a whole left side Sufficient red and swollen heat pain is uncomfortable, dialectical for gout（Damp and hot numbness type）, take the Chinese medicine composition of the present invention, a day three times, every time 3g, warm water delivery service, hence it is evident that taking a turn for the better after taking 1 course for the treatment of, after 1 course for the treatment of of following the service, cure.

Claims (3)

1. it is characterised in that being made up of following bulk drugs, the weight portion of each component is a kind of Chinese medicine composition treating gout： Rhizoma Atractylodis 9-11, Cortex Phellodendri 14-16, Semen Coiciss 28-32, Fructus Chaenomeliss 11-13, Indigo Naturaliss 5-7, Talcum 14-16, Rhizoma Anemarrhenae 8-10, Caulis Spatholobi 28- 32nd, Radix Angelicae Sinensis 14-16, Radix Paeoniae Rubra 14-16, Bi 11-13.
2. according to claim 1 treatment gout Chinese medicine composition it is characterised in that being made up of following bulk drugs, respectively The weight portion of component is：Rhizoma Atractylodis 10, Cortex Phellodendri 15, Semen Coiciss 30, Fructus Chaenomeliss 12, Indigo Naturaliss 6, Talcum 15, the Rhizoma Anemarrhenae 9, Caulis Spatholobi 30, Radix Angelicae Sinensis 15th, Radix Paeoniae Rubra 15, Bi 12.
3. the preparation method of the Chinese medicine composition for the treatment of gout as claimed in claim 1 is it is characterised in that include following walking Suddenly：
（1）Weigh each component raw material by formula proportion；
(2) Semen Coiciss are dried, fragrant vinegar, then carry out micronizing, obtain Semen Coiciss micropowder, standby；
（3）The remaining material medicine dry mixed removing in formula outside Talcum is pulverized, then crosses 60 mesh sieves, add thick in coarse powder The Mel of silty amount 1-2%, 1% Fructus Hordei Germinatus powder, 1% Rhizoma Dioscoreae powder, 150% pure water, prepare culture medium, and go out in 121 DEG C Bacterium 15 min, after cooling, by 1% inoculum concentration inoculating lactobacillus acidophilus, presses 2% inoculum concentration inoculation yeast, is 35-36 DEG C in temperature Under conditions of, ferment 24-36h, after fermentation ends, is dried under the conditions of 50-55 DEG C, obtains the mixed powder that ferments；
（4）To step（3）Obtain fermenting in mixed powder plus 8-10 times amount alcohol reflux 2-3 time, each 4-5h, merge and filter Liquid, obtains fermented extracted liquid, and decompression recycling ethanol obtains fermented extracted thick paste to no alcohol taste；
（5）Medicinal residues after alcohol reflux add and formula in Talcum add the decocting of 8-10 times amount and boil 2-3 time, each 1-1.5h, Merge decocting liquid, be concentrated into the extractum that 50-60 DEG C of relative density is 1.1-1.2；
（6）By step（2）The Semen Coiciss micropowder of acquisition, step（4）Fermented extracted thick paste, step（5）The water extracted immersing paste, mixes Close uniformly, be vacuum-packed on request, you can.
CN201611164007.2A 2016-12-16 2016-12-16 Traditional Chinese medicinal composition for treating gout and preparation method of traditional Chinese medicinal composition Pending CN106421537A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
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CN107156590A (en) * 2017-07-12 2017-09-15 广州华博生物制药研究所 Vegetable solid beverage and preparation method thereof
CN108159309A (en) * 2017-12-21 2018-06-15 霍山县中医院 A kind of Chinese prescription for treating gout
CN108379479A (en) * 2018-05-17 2018-08-10 贵州苗缘医药科技有限公司 A kind of medicine for alleviating gout
CN108853395A (en) * 2018-10-10 2018-11-23 冯小冰 One kind is for treating higher caused gout formula of uric acid and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107156590A (en) * 2017-07-12 2017-09-15 广州华博生物制药研究所 Vegetable solid beverage and preparation method thereof
CN108159309A (en) * 2017-12-21 2018-06-15 霍山县中医院 A kind of Chinese prescription for treating gout
CN108379479A (en) * 2018-05-17 2018-08-10 贵州苗缘医药科技有限公司 A kind of medicine for alleviating gout
CN108853395A (en) * 2018-10-10 2018-11-23 冯小冰 One kind is for treating higher caused gout formula of uric acid and preparation method thereof

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Application publication date: 20170222