CN101530594B - Ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis - Google Patents
Ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis Download PDFInfo
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Abstract
The invention relates to an ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis, comprising the following drug ingredients: tortoise platron, carapax trionycis, radix astragali, large head atractylodes rhizome, Chinese lobelia herb, salvia miltiorrhiza bunge, spreading hedyotis herb, chicken gizzard membrane, radix bupleuri, towel gourd vegetable sponge, beautiful sweetgum fruit, liquoric root, white paeony root, Szechuan lovage rhizome, ridge and zedoary root; all the drugs are processed into ultra-fine drug powder; sesame oil and yellow lead are mixed with the ultra-fine drug powder and the mixture is made into the ultra-fine grain traditional Chinese medicine defibrination paste; when in use, the paste is taken and is externally stuck at the area of the liver. The ultra-fine grain traditional Chinese medicine defibrination paste used for treating liver cirrhosis can improve cellular immune function, adjust humoral immunity, restrain fibroplasia of the liver and promote fiber adsorption of the liver, thus achieving the effect of reversing liver fibrosis. The defibrination paste has the advantages of having rich materials, easy preparation, low cost, treatment of internal disease with external therapy, simple treatment, convenient use, effective drugs, fast effect and good therapeutic effect and simultaneously overcoming adverse reaction of alimentary canal caused by orally taking traditional Chinese medicine by patients with dysfunction of intestines and stomach.
Description
Technical field
The invention belongs to Chinese traditional treatment liver cirrhosis application compress, fine cream falls in the ultra micron Chinese medicine of especially treating the hepatic fibrosis of liver cirrhosis cercinoma prophase pathologic change.
Background technology
Liver cirrhosis belongs to common clinical, frequently-occurring disease, difficult disease; The chronic hepatopathy overwhelming majority has hepatic fibrosis, and hepatic fibrosis is the most important pathological characters of chronic hepatopathy, and hepatic fibrosis and liver cirrhosis both were related; Have any different again; See from pathology, only have diffusivity liver fiber heavy knit to increase claim hepatic fibrosis, the diffusivity hepatic fibrosis simultaneously with lobules of liver destructurized then be liver cirrhosis; Seeing that from pathogenesis hepatic fibrosis is the cercinoma prophase pathologic change of liver cirrhosis, is reversible, and the liver cirrhosis further development that is hepatic fibrosis causes that liver failure causes death.Doctor trained in Western medicine mainly adopts antiviral, anti-immunity at present, Drug therapy hepatic fibrosis such as interferon, but expensive, and side effect is many; And curative effect is also imprecise, and there is the Chinese medicine preparation of some treatment liver cirrhosis traditional Chinese medical science aspect, certain curative effect is arranged, but all be Oral preparation; There is untoward reaction in various degree, regurgitation occurs after taking medicine, uncomfortable phenomenon in the stomaches such as vomiting; Production technology is owing to adopt the traditional mode of production processing method simultaneously, and drug quality is difficult to control, so curative effect of medication is limited to.
Summary of the invention
The purpose of this invention is to provide a kind of ultra micron Chinese medicine of treating liver cirrhosis and fall fine cream, the tcm characteristic of its utilization inner disease outer treat had both made things convenient for the treatment of patient's external application, had avoided endo-medicine to cause the untoward reaction that gastrointestinal function is disorderly simultaneously again.
The drug ratio of technical scheme of the present invention is: get Carapax et Plastrum Testudinis 8-12g, Carapax Trionycis 12-20g, Radix Astragali 15-25g, Rhizoma Atractylodis Macrocephalae 8-12g, Herba Lobeliae Chinensis 15-25g, Radix Salviae Miltiorrhizae 25-35g, Herba Hedyotidis Diffusae 15-25g, Endothelium Corneum Gigeriae Galli 8-12g, Radix Bupleuri 8-12g, Retinervus Luffae Fructus 12-20g, Fructus Liquidambaris 8-12g, Radix Glycyrrhizae 3-8g, Radix Paeoniae Alba 12-20g, Rhizoma Chuanxiong 8-12g, triangular 8-12g, Rhizoma Curcumae 8-12g, said medicine is machined to ultra micron medicated powder with modern ultra micro, and other gets Oleum sesami 1000g, Plumbum preparatium 300-500g; Earlier Oleum sesami is put into the oil refining of iron pan internal heating, refining adds the Plumbum preparatium powder of heat drying crushing screening in the iron pan Oleum sesami when dripping into pearl; Stir, and after reaching appropriate level with " dripping into pearl " method inspection, again ointment is blown slowly in the impouring cold water box; Constantly stir with waddy, it is become band, treat to take out after the ointment cooling is condensed and pinch pressure repeatedly; And process agglomerate, again the ointment agglomerate is soaked in the cold water more than three days, to remove " fire-toxin "; Change water every day once, remove the ointment agglomerate of clean fire-toxin then and insert the fusing of iron pan internal heating, add above-mentioned ultra micron medicated powder; Pick a certain amount of ointment stand with bamboo let behind the mix homogeneously and be applied on the paper, the stand is coated with wants even rounding, every adhesive plaster net weight 5 grams; During use, the cream thermoplastic of getting it filled, external application patient hepatic region; One time one subsides, two days once.
The etiology and pathogenesis of liver cirrhosis is poison, empty, the stasis of blood, and the residual difficulty of epidemic disease caused by damp-heat pathogen poison is full of the startup factor and lasting factor, and deficiency of vital QI is an endogenous cause of ill, and the blood stasis yin collaterals is a pathologic basis; Pathogen usually intruding into collateral in protracted disease, prolonged illness must be empty, and hepatopathy makes the spleen pathological process that is inevitable, and liver cirrhosis patient causes gastrointestinal function low because prolonged illness is weakened body resistance with liver disease affecting spleen; Drug absorption is poor, and regurgitation, vomiting phenomenon appear in endo-medicine easily, and therefore, the effective way of treatment liver cirrhosis is an inner disease outer treat; Inner disease outer treat is a tcm characteristic, and external treatment great master Wu Shiji says " reason of external treatment, the i.e. reason of treatment by oral administration of medicines; the medicine of external treatment is the medicine of treatment by oral administration of medicines also are though control outside not different from being in harmony also interior ".So it is etiology and pathogenesis and motherland's Traditional Chinese medical theory according to liver cirrhosis that fine cream falls in the ultra micron Chinese medicine that said medicine is formed, on the basis of secret prescription handed down in the family from generation to generation, combine modern ultra micron herbal pharmaceutical technology, the dialectical and science ancestral side of differential diagnosis of diseases, just in the Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, the reinforcing the heart of nourishing blood; Carapax Trionycis hard masses softening and resolving is brought down a fever to remove and is steamed Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, expelling pus and promoting granulation, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI; The dampness diuretic, the Herba Lobeliae Chinensis inducing diuresis to remove edema, heat-clearing and toxic substances removing, the Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire; Microcirculation improvement, the epidemic disease poison is separated in the Herba Hedyotidis Diffusae heat clearing away, Endothelium Corneum Gigeriae Galli invigorating the stomach and promoting digestion, Radix Bupleuri reconciling superficies and interior, soothing the liver yang invigorating; Retinervus Luffae Fructus collateral dredging promoting blood circulation by removing wind, the Fructus Liquidambaris dispelling, collateral-activating, diuresis is stimulated the menstrual flow, Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving spasm to stop pain; The side's of mediation medicine, Radix Paeoniae Alba invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, triangular, Rhizoma Curcumae removing blood stasis circulation of qi promoting; The removing food stagnancy pain relieving, microcirculation improvement gathers heat-clearing and toxic substances removing altogether, blood circulation promoting and blood stasis dispelling, tonify deficiency is set upright; Regulate humoral immunization, improve cellular immune function, promote the liver fiber absorbs, suppress hepatic fibroplasia, thereby reach the effect that reverses hepatic fibrosis.
Adopt the ultra grain of the present invention Chinese medicine to fall fine cream treatment liver cirrhosis and can improve cellular immune function, regulate humoral immunization, suppress hepatic fibroplasia, promote the liver fiber absorbs; Thereby reach the effect that reverses hepatic fibrosis, have abundant raw material, preparation easily, and is with low cost; Inner disease outer treat, medicine is effective, and treatment is simple; Easy to use, avoid patient's gastrointestinal function disorderly simultaneously, Chinese medicine for oral administration causes advantage and effects such as side effect of digestive tract.
The specific embodiment
Embodiment is detailed below:
Get Carapax et Plastrum Testudinis 8-12g, Carapax Trionycis 12-20g, Radix Astragali 15-25g, Rhizoma Atractylodis Macrocephalae 8-12g, Herba Lobeliae Chinensis 15-25g, Radix Salviae Miltiorrhizae 25-35g, Herba Hedyotidis Diffusae 15-25g, Endothelium Corneum Gigeriae Galli 8-12g, Radix Bupleuri 8-12g, Retinervus Luffae Fructus 12-20g, Fructus Liquidambaris 8-12g, Radix Glycyrrhizae 3-8g, Radix Paeoniae Alba 12-20g, Rhizoma Chuanxiong 8-12g, triangular 8-12g, Rhizoma Curcumae 8-12g, said medicine is processed into ultra micron medicated powder, other gets Oleum sesami 1000g, Plumbum preparatium 300-500g; Earlier Oleum sesami is put into the oil refining of iron pan internal heating; Refining is to dripping into pearl, and the Plumbum preparatium powder with crushing screening adds in the iron pan Oleum sesami again, stirs; After reaching appropriate level with " dripping into pearl " method inspection; Again ointment is blown slowly in the impouring cold water box, constantly stir, it is become band with wooden stick; Take out after cooling is condensed and pinch pressure repeatedly; Process agglomerate, again the ointment agglomerate was soaked in the cold water more than three days, change water every day once.The ointment agglomerate of removing behind the poison that goes out is only inserted the fusing of iron pan internal heating, inspection old tender suitable after, add above-mentioned ultra micron medicated powder; Stir, pick a certain amount of ointment stand with bamboo let then and be applied on the paper, control every weight 5 grams; Guarantee to spread out to be coated with and want even rounding to get final product, during use, the cream of getting it filled is heated softening; External application patient hepatic region, one time one subsides, two days are once.
Clinical practice divides treatment group and matched group, and the treatment group adopts ultra micron Chinese medicine to fall fine cream thermoplastic, the external application patient hepatic region liver cave of healing, subsides in two days; Manifold card 3 months was a course of treatment, and two courses of treatment are observed in treatment, and the treatment group is treated 36 people altogether, wherein male 26 people; Woman 10 people, by state of an illness weight branch, slight 20 people, moderate 16 people; Press the Chinese medical discrimination branch, syndrome of stagnation of liver qi 8 people, insufficiency of the spleen leading to overabundance of dampness disease 6 people, Blood stasis 22 people; It is for oral administration that matched group adopts ultra micron Chinese medicine to fall fine cream side, every day potion, serveing on three months is a course of treatment, two courses of treatment are observed in treatment, treat 35 people altogether; Wherein male 27 people, women 8 people, by state of an illness weight branch, slight 18 people, moderate 17 people; Press the Chinese medical discrimination branch, syndrome of stagnation of liver qi 8 people, insufficiency of the spleen leading to overabundance of dampness is demonstrate,proved 7 people, Blood stasis 20 people, therapeutic outcome: 36 philtrums are organized in treatment; Produce effects 15 people, effective 14 people, invalid 7 people, total effective rate 80.6%, matched group 35 philtrums; Produce effects 14 people, effective 13 people, invalid 8 people, total effective rate 77.1%.
Serum liver fibrosis testing result before and after two groups of treatments:
Claims (1)
1. fine cream falls in a ultra micron Chinese medicine of treating liver cirrhosis, it is characterized in that, the composition proportioning of this medicine is: Carapax et Plastrum Testudinis 8-12g, Carapax Trionycis 12-20g, Radix Astragali 15-25g, Rhizoma Atractylodis Macrocephalae 8-12g, Herba Lobeliae Chinensis 15-25g, Radix Salviae Miltiorrhizae 25-35g, Herba Hedyotidis Diffusae 15-25g, Endothelium Corneum Gigeriae Galli 8-12g, Radix Bupleuri 8-12g, Retinervus Luffae Fructus 12-20g, Fructus Liquidambaris 8-12g, Radix Glycyrrhizae 3-8g, Radix Paeoniae Alba 12-20g, Rhizoma Chuanxiong 8-12g, triangular 8-12g, Rhizoma Curcumae 8-12g, and said medicine is processed into ultra micron medicated powder with the ultra micron pulverizer; Get Oleum sesami 1000g, Plumbum preparatium 300-500g, and Oleum sesami is put into iron pan internal heating oil refining, refining is when dripping into pearl, and the Plumbum preparatium powder that again drying and crushing is sieved adds in the Oleum sesami; Stir, and with after the Cheng Zhufa inspection appropriate level of dripping, ointment is blown slowly in the impouring cold water box, constantly stir with wooden stick; It is become band, treat to take out after the ointment cooling is condensed and pinch pressure repeatedly, process agglomerate, again the ointment agglomerate is soaked in the cold water; To remove " fire-toxin ", change water every day once, take out after three days go clean " fire-toxin " and the plaster agglomerate; Insert iron pan internal heating fusing, inspection old tender suitable after, add above-mentioned ultra micron medicated powder; Mixing stirs, and picks a certain amount of plaster stand with bamboo let and is coated with on the paper, controls every subsides drug weight net weight 5 grams; Guarantee that the stand is coated with rounding, during use, gets the plaster thermoplastic; The external application hepatic region, one time one subsides, two days are once.
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| CN102198242B (en) * | 2011-06-06 | 2012-05-23 | 许从玉 | Traditional Chinese medicine composition for treating hysteromyoma |
| CN102988906B (en) * | 2013-01-08 | 2014-05-07 | 于收 | Traditional Chinese medicine combination for treating cirrhosis |
| CN105194553B (en) * | 2015-10-13 | 2019-01-11 | 肇庆医学高等专科学校 | A kind of Chinese medicine composition for preventing and treating cirrhosis Esophageal varicosis rupture hemorrghage |
| CN105194554A (en) * | 2015-10-13 | 2015-12-30 | 肇庆医学高等专科学校 | Preparation method of traditional Chinese medicine composition for preventing and treating cirrhosis esophageal variceal bleeding |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1147398A (en) * | 1996-08-29 | 1997-04-16 | 李安治 | Chinese patent medicine for treating cirrhosis |
| CN1879864A (en) * | 2006-05-14 | 2006-12-20 | 干石亮 | Soup formulation for treating liver and kidney Yin defect type cirrhosis ascites, and its preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1147398A (en) * | 1996-08-29 | 1997-04-16 | 李安治 | Chinese patent medicine for treating cirrhosis |
| CN1879864A (en) * | 2006-05-14 | 2006-12-20 | 干石亮 | Soup formulation for treating liver and kidney Yin defect type cirrhosis ascites, and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 谷井文等.降纤1号方治疗肝纤维化42例.《湖南中医杂志》.2004,第20卷(第20期),30-31. * |
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