CN106420485A - Oligopeptide skin smoothing rejuvenating powder - Google Patents

Oligopeptide skin smoothing rejuvenating powder Download PDF

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CN106420485A
CN106420485A CN201610972862.XA CN201610972862A CN106420485A CN 106420485 A CN106420485 A CN 106420485A CN 201610972862 A CN201610972862 A CN 201610972862A CN 106420485 A CN106420485 A CN 106420485A
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oligopeptide
skin
powder
parts
ratio
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苏建华
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Beijing Acne Research Institute
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Beijing Acne Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to skin smoothing products in the field of cosmetics, and particularly relates to oligopeptide skin smoothing rejuvenating powder. The oligopeptide skin smoothing rejuvenating powder is prepared from, by weight, 0.5-1 part of mannitol, 1-2 parts of oligopeptide-1, 1-2 parts of oligopeptide-3, 0.2-0.5 part of sodium dihydrogen phosphate, 0.2-0.5 part of disodium hydrogen phosphate, 1-2 parts of glucan and 1-2 parts of tripeptide-1. Ultraviolet protection and moisture preserving and moistening are effectively combined, and the skin is protected against ultraviolet light and outside damage; the oligopeptide skin smoothing rejuvenating powder is capable of deeply moistening the skin, promoting metabolism, accelerating skin cell neogenesis, improving skin compactness, smoothing wrinkles, delaying skin ageing and fast recovering skin vitality and vigour.

Description

A kind of flat flesh of oligopeptide repairs powder
Technical field
The present invention relates to flat flesh product is and in particular to a kind of flat flesh of oligopeptide repairs powder in cosmetic field.
Background technology
Skin is the maximum organ of human body, mainly has both sides barrier action, protects human body and be not subject to outside stimuluss Or injury:On the one hand prevent the loss of internal water, electrolyte and other materials;On the other hand stop invading of extraneous harmful substance Enter.Skin remains stablizing of human internal environment, is physiologically playing important defencive function, skin also assists in human body simultaneously Metabolic process.Skin, after by ultraviolet overexposure, can damage epidermis cell;Activation Tyrosinase, can accelerate pigment to close Become, destroy the moisture-keeping functions of skin, make skin become drying, make the elastic fiberss in skin corium impaired, so that microgroove is produced.Strong Under burning sun light irradiation, also can cause skin inflammation, burn.The time being acted on by ultraviolet and pollutants in air with skin increases Long, easily lack nutrition, and then make skin dehydration, destroy skin keratin, cause pachylosiies, follow the string, long-term skin Skin drying results even in wrinkle to be occurred and skin aging.
Water is the key component of living cells, and most cellular biochemical reaction is carried out all in water environment.? In living cells, the ratio of water accounts for the 70% about of gross weight, and relative constancy.Although hydrone is led to simple penetration diffusion way Cell membrane, but diffusion velocity is slowly.Research has shown that, the fast transport that hydrone crosses over cell membrane is by cell membrane On a kind of aquaporin realize.Because keratodermatitis are that protection internal water provides effective barrier, so angle The aquaporin that matter is formed on cell is significant for maintaining skin hydration to act on, and aquaporin becomes skin moisture-keeping Recent studies on direction.Exogenous supplementary oligopeptide -1 can induce aquaporin high expression in human body cell, this expression also as Concentration raise and the prolongation of time and increase.
The flat flesh product function of moisturizing in the market is single:General moisturizer can not effectively sun-proof it is impossible to opposing ultraviolet Line is to the damage of skin it is impossible to effective protection skin is not encroached on by extraneous harmful substance.Common sunscreen product does not have to skin Have and moisten and maintenance effect, coating time is oversize, increases skin loadings, so that skin is tarnished.Calm down cicatrix product for dispelling Except cicatrix has certain effect, for flat flesh effect on driving birds is not good, nor possesses moisture-keeping efficacy.If the cosmetic of various difference in functionalitys Product overlap and use, and not only can not play respective effect, also can increase the burden of skin, also can produce anti-between part cosmetics Should, constitute the potential danger of skin.
Content of the invention
For above-mentioned weak point of the prior art, the invention provides a kind of flat flesh of oligopeptide repairs powder, the present invention is real Show effective combination of ultraviolet protection and moisturizing, preferably protect skin from ultraviolet and external injury;Being capable of deep layer Moist skin, enhances metabolism, and accelerates skin cell newborn, strengthens skin compactness, calms down wrinkle, delaying skin aging, The vigor and vitality of fast quick-recovery skin.
A kind of flat flesh of oligopeptide repairs powder, including:
Mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and tripeptides -1, above-mentioned composition By weight percentage, ratio is respectively 0.5-1 part, 1-2 part, 1-2 part, 0.2-0.5 part, 0.2-0.5 part, 1-2 part, 1- 2 parts.
Further, described mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and three The ratio by mass percentages of peptide -1, preferably 0.7-1 part, 1.5-2 part, 1-1.5 part, 0.3-0.5 part, 0.2-0.4 part, 1.5-2 part, 1-1.5 part.
Further, described mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and three The ratio by mass percentages of peptide -1, preferably 0.7 part, 1.5 parts, 1.5 parts, 0.3 part, 0.3 part, 1.5 parts, 1.5 parts.
Further, above-mentioned formula also comprises in wild Fructus Citri flower extract, civilian king's one-pen and hamamelis extract Plant or several.
Further, the ratio of described open country Fructus Citri flower extract by weight percentage, is 0.2-0.5 part, preferably 0.3 part.
Further, the ratio of described literary composition king's one-pen by weight percentage, is 0.2-0.5 part, preferably 0.4 Part.
Further, the ratio of described hamamelis extract by weight percentage, is 0.5-1 part, preferably 0.7 Part.
Further, described hamamelis extract is pressed hot dipping and is measured, and the amount of water-soluble extractivess is no less than 15%.
Wherein, described mannitol (English name mannitol) is the sugar that the aldehyde radical of mannose is reduced to alcohol radical and is formed Alcohol.Easily crystallize.Natural product are widely present in plant exudates, exist in the organisms such as algae, edible fungi and lichens Interior.Because Mannitol has special physics and chemical property, therefore have in industries such as food, medicine and chemical industry and extensively should With.Mannitol industrialized production mainly adopts Thallus Laminariae (Thallus Eckloniae) extraction method and chemical synthesiss at present.
Wherein, described oligopeptide is a kind of classification of polypeptide, and molecular weight section is typically below 1000 dalton, also referred to as little Peptide, oligopeptide, oligopeptide, or referred to as small active peptides, are typically made up of 2--6 aminoacid, and exceed is known as polypeptide, ammonia Base acid is referred to as protein for more than 50 above polypeptides.Difference with other peptides is to be not required to digest in human body, you can directly inhale Receive.Oligopeptide can be divided into again:Oligopeptide -1, oligopeptide -3, oligopeptide -5, oligopeptide -6 etc., oligopeptide -6 is also called hexapeptide or Argireline.Traditional Protein digestibility, absorption approach think:Protein, in enteric cavity, generates free amino acid by peptide protease and Chymotrypsin effect With oligopeptide (containing 2~6 amino acid residues), oligopeptide is hydrolyzed into free amino acid in the presence of peptidase completely, and with free Amino acid form enters blood circulation.Oligopeptide absorption characteristics are:1. it is not required to digest, directly absorb.It is not required to when 2. absorbing consume people Physical ability amount.3. human intestines and stomach's function burden will not be increased.4. there is preferential absorption feature.5. human body is promoted to inhale with self-energy Receive.6., when absorption of human body function is lost, force absorption of human body.7. 100% it is absorbed by the body.8. absorb quick.Inhale than human body Receive macro-molecular protein fast 129600 seconds, fast compared with human amino acid 64800 seconds.9. there is carrier function.People can be eaten Other nutrition are loaded on its body, are transported to human body cell, tissue.10. become means of transport in human body, by various micro units Element transports partes corporis humani position.Also there is extremely strong activity and physiological function multiformity.The little oligopeptide of molecular weight can compare polypeptide There is higher percutaneous permeability it is easier to be absorbed by human body skin, simultaneously because molecular weight is little having arrived to a certain degree, biological activity Just there occurs qualitative leap.Peptide molecular weight is less, and " amino acid chain " is shorter, is more easily absorbed and utilized by the body.It is widely used in The fields such as daily use chemicals beauty treatment, hair-washing hair-care, health care of food product, biomedicine, weaving.
Wherein, described sodium dihydrogen phosphate (sodium dihydrogen phosphate), also known as sodium acid phosphate, molecule Formula is NaH2PO4·2H2O and NaH2PO4, relative molecular mass is 156.01 and 119.98.Divide anhydride and two water things, two water things For colourless to white crystals or crystalline powder, anhydride is white powder or granule.Soluble in water, it is practically insoluble in ethanol. 100 DEG C lose continuation heating after water of crystallization, then generate acidic sodium pyrophosphate.Sodium dihydrogen phosphate is as buffer agent and water softening device, quilt It is applied to following industry:Brewage, in the food processing such as milk product, as acidity regulator;Meat productss are used as sticking agent and Stabilizer;In low power concentrated milk, condensed milk and dilute cream;Pork luncheon meat, cooked ham, cold cuts end (alone or with other phosphate close With);Cold drink etc..
Wherein, described disodium hydrogen phosphate (Dibasic Sodium Phosphate), also known as dibasicity sodium phosphate, molecule Formula Na2HPO4, molecular weight 141.96, white powder, lamellar or shot-like particle.Disodium hydrogen phosphate easy-weathering in atmosphere, puts during room temperature It is placed in the air, easy-weathering loses 5 water of crystallization and forms seven water thing (Na2HPO4.7H2O), it is heated to when 100 DEG C losing all Water of crystallization forms anhydride, decomposes and become sodium pyrophosphate when 250 DEG C.Water soluble, do not dissolve in alcohol.Aqueous solution is in that alkalescence is reacted (PH of 0.1-1N solution is about 9.0).Lose water of crystallization at 100 DEG C and form anhydride, when 250 DEG C, decompose coking sodium phosphate.1% The pH value of aqueous solution is 8.8~9.2;Insoluble in alcohol.Melt and lose 5 water of crystallization when 35.1 DEG C.Disodium hydrogen phosphate is used for making Make citric acid, water softener, fabric weighting agent, fireproof agent, and for glaze, welding agent, medicine, pigment, food industry and produce it His phosphate is used as industrial water quality treatment agent, printing and dyeing detergent, quality improver, nertralizer, antibiotic nutrient chemical, biochemical treatment Agent food quality modifying agent.
Wherein, described glucosan (dextran or glucan), also known as dextran, molecular formula [C6H10O5]n.Glucosan is Refer to the homotype polysaccharide forming with glucose for monosaccharide, bonded with glucosides between glucose unit.Class wherein according to glycosidic bond Type can be divided into alpha- glucosan and beta- glucosan again.Study in alpha- glucosan and using more for dextran, It is a kind of polysaccharide.It is present in the mucus that certain micro-organisms is secreted in growth course.Glucosan has higher molecular weight, main Will be by D- glucopyanosyl with α, 1-6 is bonded, and side chain point has 1-2,1-3,1-4 to connect.With microbe species and growth The difference of condition, its structure also has difference.It has high specific rotatory power, and partial hydrolysiss mainly obtain dextrinose.Glucosan A part of whole blood can be replaced in transfusion procedure, the expansion agent (referred to as plasma substitute) as Plasma volumes.Commodity blood plasma substitute It is the glucosan after partial hydrolysiss, be dissolved in normal saline.Glucosan is the homopolysaccharide being polymerized by several glucose molecules.Portugal Polysaccharide is not monosaccharide but oligosaccharide.The polysaccharide that beta glucan active structure is made up of glucose unit, their great majority By β -1,3 combinations, this is the mode that Fructus Vitis viniferae sugar chain connects.It can activated macrophage, neutrophils etc., therefore can Improve the content of leukin, the basic element of cell division and distinct antibodies, stimulate the immune system of body comprehensively, allow body to have more It is ready to resist the disease that microorganism causes.Beta glucan can make the lymphocyte of injured body produce cytokine (IL-1) Ability is rapid to recover normal, effectively adjusts human body immune function.
Wherein, described tripeptides -1 (tripeptide-1), also known as corium growth-promoting factors, white powder, effect and effect:Thorn Sharp skin tissue recovering, reinvents the biochemical function of skin, thus improving skin tightness, for crease-resistant and defying age.
Using technique scheme, the present invention includes following Advantageous Effects:
Oligopeptide -1 in raw material of the present invention and oligopeptide -3 are somatomedin, can be with stimulating cellular growth, old and feeble, the anti-powder of suppression Thorn, remove trace, accelerate wound healing, to preventing and to nurse acne respond well.
Present invention achieves effective combination of ultraviolet protection and moisturizing, preferably protect skin from ultraviolet and outer Boundary injures;Deep layer can moisten skin, enhance metabolism, accelerate skin cell newborn, strengthen skin compactness, calm down wrinkle Stricture of vagina, delaying skin aging, the vigor and vitality of fast quick-recovery skin.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail.
The invention provides a kind of flat flesh of oligopeptide repairs powder, including:
Mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and tripeptides -1, above-mentioned composition By weight percentage, respectively 0.5-1 part, 1-2 part, 1-2 part, 0.2-0.5 part, 0.2-0.5 part, 1-2 part, 1-2 part.
It is further preferred that described mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan With the ratio by mass percentages of tripeptides -1, preferably 0.7-1 part, 1.5-2 part, 1-1.5 part, 0.3-0.5 part, 0.2-0.4 Part, 1.5-2 part, 1-1.5 part.
It is further preferred that described mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, disodium hydrogen phosphate, Portugal gather Sugar and tripeptides -1 ratio by mass percentages, preferably 0.7 part, 1.5 parts, 1.5 parts, 0.3 part, 0.3 part, 1.5 parts, 1.5 Part.
In specific embodiment, above-mentioned recipe ingredient ratio is as shown in table 1 below:
Table 1. inventive formulation component proportion ratio table
It is further preferred that above-mentioned formula also comprises wild Fructus Citri flower extract.
It is further preferred that the ratio of described open country Fructus Citri flower extract is by weight percentage, it is 0.2-0.5 Part, preferably 0.3 part.
It is further preferred that described open country Fructus Citri flower extract is the water extraction dried powder of wild Fructus Citri, described open country Fructus Citri flower extract is pressed hot dipping and is measured, and the amount of water-soluble extractivess is no less than 10%.
It is further preferred that above-mentioned formula also comprises civilian king's one-pen.
It is further preferred that the ratio of described literary composition king's one-pen is by weight percentage, it is 0.2-0.5 part, excellent Select 0.4 part.Described literary composition king's one-pen is the dried powder of civilian king's one-pen.
It is further preferred that above-mentioned formula also comprises hamamelis extract.
It is further preferred that the ratio of described hamamelis extract is by weight percentage, it is 0.5-1 part, excellent Select 0.7 part.
It is further preferred that described hamamelis extract is the water extraction dried powder of the root of Radix Hamamelidis Molliss, described gold Thread prunus mume extract is pressed hot dipping and is measured, and the amount of water-soluble extractivess is no less than 15%.
Wherein, described open country Fructus Citri (latin name Capparis bodinieri) belongs to for Capparaceae Capparis Spirrosa, evergreen shrubss Or dungarunga.Bitter in the mouth, cold in nature.Indication:Herb is medicinal, heat-clearing and toxic substances removing;Hemostasis, antiinflammatory, convergence, dispelling, collateral-activating.
Wherein, described literary composition king's one-pen is Balanophoraceae plant Balanophora involicrata Hook.f. (Balanophora involucrata) or Serpentiss The meat herbaceous plant of wild rice (BalanophoraJ Wjaponica), is grown under the hillside of height above sea level 1000-2500 rice, colonizes in On the root of xylophyta.Civilian king one-pen Herb can be cooked medical material, has hemostasis, granulation promoting, analgesic effect.
Wherein, described Radix Hamamelidis Molliss (Hamamelis mollis Oliver) are Rosales Hamamelidaceae Plants Radix Hamamelidis Molliss Root, fragrant in another name wood, cattle steps on fruit.Include multiple tannin such as Ellagtannin and Hamamlitannin, sebum can be adjusted and divide Secrete, Hydrolyzed Protein and Milk Protein.Promote lymph blood circulation, the effect there is calmness, pacifying, cracking, sunburn, acne are had and change Kind effect.The regeneration capacity at skin night can effectively be helped.Remove eye pouch, loosen and relax oily skin or allergy skin effect Really excellent.Have releive, restrain, the effect of antibacterial, have convergence oil-control, the significant curative effect of sterilization, for children in adolescence or go out The more serious skin of oily condition, is only selection.Radix Hamamelidis Molliss have functions that deep layer cleaning can make skin defying age.Hair can be restrained Hole, wet, the quiet flesh of benefit.Radix Hamamelidis Molliss Bearberry Extract, effect, balance skin pH value and the fat secretion of calm skin, purify pore, repair Impaired skin, effectively adjusts the pore of diastole hence it is evident that convergence enlarged pores, prevents blackhead, acne from producing, so that skin is quickly presented Fine and smooth, smooth, tight.Hazel extract is also used as moisturizing composition, as astringent, facial film maintenance water and moisturizing Moisturizer uses.
Wherein, described open country Fructus Citri flower extract and hamamelis extract shine water-soluble extractivess algoscopy (general rule 2201) item Under hot dipping measure the content of its water-soluble extractives.
Ultraviolet protection is effectively combined by the above embodiment of the present invention with moisturizing, preferably protects skin from ultraviolet And external injury;Deep layer can moisten skin, enhance metabolism, accelerate skin cell newborn, strengthen skin compactness, calm down Wrinkle, delaying skin aging, the vigor and vitality of fast quick-recovery skin.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for the skill of this area For art personnel, the present invention can have various modifications and variations.All within the spirit and principles in the present invention, made any repair Change, equivalent, improvement etc., should be included within the scope of the present invention.

Claims (8)

1. a kind of flat flesh of oligopeptide repairs powder it is characterised in that including:Mannitol, oligopeptide -1, oligopeptide -3, sodium dihydrogen phosphate, phosphorus Sour disodium hydrogen, glucosan and tripeptides -1, by weight percentage, ratio is respectively 0.5-1 part, 1-2 part, 1- to above-mentioned composition 2 parts, 0.2-0.5 part, 0.2-0.5 part, 1-2 part, 1-2 part;Remaining is solvent.
2. the flat flesh of oligopeptide according to claim 1 repair powder it is characterised in that described mannitol, oligopeptide -1, oligopeptide - 3rd, the ratio by mass percentages of sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and tripeptides -1, preferably 0.7-1 part, 1.5- 2 parts, 1-1.5 part, 0.3-0.5 part, 0.2-0.4 part, 1.5-2 part, 1-1.5 part.
3. the flat flesh of oligopeptide according to claim 2 repair powder it is characterised in that described mannitol, oligopeptide -1, oligopeptide - 3rd, the ratio by mass percentages of sodium dihydrogen phosphate, disodium hydrogen phosphate, glucosan and tripeptides -1, preferably 0.7 part, 1.5 parts, 1.5 parts, 0.3 part, 0.3 part, 1.5 parts, 1.5 parts.
4. powder is repaired it is characterised in that above-mentioned formula also comprises wild Fructus Citri according to the flat flesh of the arbitrary described oligopeptide of claim 1-3 Flower extract, civilian one or more of king's one-pen and hamamelis extract.
5. the flat flesh of oligopeptide according to claim 4 repairs powder it is characterised in that the proportioning ratio of described open country Fructus Citri flower extract Example by weight percentage, is 0.2-0.5 part, preferably 0.3 part.
6. the flat flesh of oligopeptide according to claim 4 repairs powder it is characterised in that the ratio of described literary composition king's one-pen is pressed Percentage by weight meter, is 0.2-0.5 part, preferably 0.4 part.
7. the flat flesh of oligopeptide according to claim 4 repairs powder it is characterised in that the ratio of described hamamelis extract By weight percentage, it is 0.5-1 part, preferably 0.7 part.
8. the flat flesh reparation powder of oligopeptide according to claim 7 is it is characterised in that described hamamelis extract presses hot dipping survey Fixed, the amount of water-soluble extractivess is no less than 15%.
CN201610972862.XA 2016-11-07 2016-11-07 Oligopeptide skin smoothing rejuvenating powder Pending CN106420485A (en)

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CN109966169A (en) * 2019-04-23 2019-07-05 嫦娥创新(武汉)生物科技有限公司 A kind of external preparation for skin peptide composition and its application
CN110179728A (en) * 2019-05-13 2019-08-30 广州丽彦妆生物科技有限公司 A kind of edible freeze-dried powder preparation and preparation method thereof
CN112043619A (en) * 2020-08-20 2020-12-08 广州优理氏生物科技有限公司 Peptide composition with repairing effect and preparation method and application thereof
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