CN106414738A - 人kras中单核苷酸多态性的检测 - Google Patents

人kras中单核苷酸多态性的检测 Download PDF

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Publication number
CN106414738A
CN106414738A CN201580020715.6A CN201580020715A CN106414738A CN 106414738 A CN106414738 A CN 106414738A CN 201580020715 A CN201580020715 A CN 201580020715A CN 106414738 A CN106414738 A CN 106414738A
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seq
probe
kras
primer
sample
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English (en)
Chinese (zh)
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S.Y.侯
A.H.夏
X.陈
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Abbott Laboratories
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Abbott Laboratories
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201580020715.6A 2014-06-24 2015-06-23 人kras中单核苷酸多态性的检测 Pending CN106414738A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462016312P 2014-06-24 2014-06-24
US62/016312 2014-06-24
PCT/US2015/037268 WO2015200377A1 (en) 2014-06-24 2015-06-23 Detection of single nucleotide polymorphisms in human kras

Publications (1)

Publication Number Publication Date
CN106414738A true CN106414738A (zh) 2017-02-15

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CN201580020715.6A Pending CN106414738A (zh) 2014-06-24 2015-06-23 人kras中单核苷酸多态性的检测

Country Status (5)

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US (2) US9909187B2 (enExample)
EP (1) EP3161151A1 (enExample)
JP (1) JP2017522015A (enExample)
CN (1) CN106414738A (enExample)
WO (1) WO2015200377A1 (enExample)

Cited By (5)

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Publication number Priority date Publication date Assignee Title
CN107937524A (zh) * 2017-12-05 2018-04-20 中源协和基因科技有限公司 人类kras基因突变检测试剂盒及检测方法
CN110452983A (zh) * 2019-07-05 2019-11-15 凯威康达(厦门)生物医药科技有限公司 一种检测kras基因12密码子6种热点突变的引物、探针、检测体系和试剂盒及方法
CN110650792A (zh) * 2017-08-23 2020-01-03 诺尔有限公司 用于存储试剂的存储介质,利用其的检查方法及检查模块
CN111373055A (zh) * 2017-09-08 2020-07-03 豪夫迈·罗氏有限公司 用于癌症的诊断和治疗方法
CN112795653A (zh) * 2021-02-08 2021-05-14 深圳市核子基因科技有限公司 Kras基因突变检测的引物探针组、试剂盒及其应用

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JP6754202B2 (ja) * 2016-03-15 2020-09-09 アークレイ株式会社 Ｋ−ｒａｓ遺伝子増幅用フォワードプライマーセット、Ｋ−ｒａｓ遺伝子増幅用キット、Ｋ−ｒａｓ遺伝子増幅方法、多型解析方法、及び薬効判定方法
CA3022947A1 (en) 2016-05-04 2017-11-09 Children's Hospital & Research Center At Oakland Rapid extraction of nucleic acids from clinical samples for downstream applications
US11377698B2 (en) * 2018-09-05 2022-07-05 Inivata Ltd. Method of treating a cancer patient without the need for a tissue biopsy
WO2022108933A1 (en) * 2020-11-17 2022-05-27 Cy Molecular Diagnostics, Inc. Compositions and methods for high sensitivity detection of rare mutations
CN117858956A (zh) * 2021-08-25 2024-04-09 南京金斯瑞生物科技有限公司 一种用于检测单碱基突变的引物组和基因芯片方法

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CN103114146A (zh) * 2013-02-28 2013-05-22 张戈 一种检测K-ras基因突变的试剂盒及其检测方法
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CN101423866A (zh) * 2007-10-31 2009-05-06 上海长海医院 检测K-ras基因突变的PNA、探针、引物及方法
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CN103114146A (zh) * 2013-02-28 2013-05-22 张戈 一种检测K-ras基因突变的试剂盒及其检测方法

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110650792A (zh) * 2017-08-23 2020-01-03 诺尔有限公司 用于存储试剂的存储介质,利用其的检查方法及检查模块
CN110650792B (zh) * 2017-08-23 2021-11-05 诺尔有限公司 用于存储试剂的存储介质,利用其的检查方法及检查模块
CN111373055A (zh) * 2017-09-08 2020-07-03 豪夫迈·罗氏有限公司 用于癌症的诊断和治疗方法
US11859252B2 (en) 2017-09-08 2024-01-02 Genentech, Inc. Diagnostic and therapeutic methods for cancer
CN107937524A (zh) * 2017-12-05 2018-04-20 中源协和基因科技有限公司 人类kras基因突变检测试剂盒及检测方法
CN110452983A (zh) * 2019-07-05 2019-11-15 凯威康达(厦门)生物医药科技有限公司 一种检测kras基因12密码子6种热点突变的引物、探针、检测体系和试剂盒及方法
CN110452983B (zh) * 2019-07-05 2022-09-20 凯威康达(厦门)生物医药科技有限公司 一种检测kras基因12密码子6种热点突变的引物、探针、检测体系和试剂盒及方法
CN112795653A (zh) * 2021-02-08 2021-05-14 深圳市核子基因科技有限公司 Kras基因突变检测的引物探针组、试剂盒及其应用

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EP3161151A1 (en) 2017-05-03
US20180171417A1 (en) 2018-06-21
WO2015200377A1 (en) 2015-12-30
JP2017522015A (ja) 2017-08-10
US9909187B2 (en) 2018-03-06
US20150368725A1 (en) 2015-12-24

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Application publication date: 20170215