CN106389646A - Traditional Chinese medicine compound for treating premature white hair - Google Patents

Traditional Chinese medicine compound for treating premature white hair Download PDF

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Publication number
CN106389646A
CN106389646A CN201610975228.1A CN201610975228A CN106389646A CN 106389646 A CN106389646 A CN 106389646A CN 201610975228 A CN201610975228 A CN 201610975228A CN 106389646 A CN106389646 A CN 106389646A
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parts
chinese medicine
traditional chinese
medicine compound
radix
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CN201610975228.1A
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Chinese (zh)
Inventor
姜迪蛟
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Chengdu Ling Xi Luxuries Technology Co Ltd
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Chengdu Ling Xi Luxuries Technology Co Ltd
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Priority to CN201610975228.1A priority Critical patent/CN106389646A/en
Publication of CN106389646A publication Critical patent/CN106389646A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)

Abstract

The invention discloses a traditional Chinese medicine compound for treating premature white hair. The traditional Chinese medicine compound comprises 4-17 parts of mulberry fruits, 4-12 parts of dried rehamnnia roots, 3-16 parts of red peony roots, 5-15 parts of folium mori, 7-21 parts of cortex moutan, 5-18 parts of chrysanthemum, 15-30 parts of fleece-flower roots and radix rehmanniae and fructus viticis, wherein morus notabili or morus bombycis is taken as the mulberry fruits. In a use process, the traditional Chinese medicine compound disclosed by the invention is free from untoward effects; the traditional Chinese medicine compound has an obvious effect on treating premature white hair; the selected medicine materials have no toxic or side effect to each other; the slight and serious premature white hair patients both can use the traditional Chinese medicine compound; the application scope is wide; the quality of the hair can be increased; the internal heat of the body can be eliminated; and the mental state can be improved.

Description

A kind of Chinese medicine composition for treating teen-ager leukotrichia
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine composition for treating teen-ager leukotrichia.
Background technology
Modern medicine is thought, the generation of teen-ager leukotrichia is how chronic with Nervous and Mental Factors, malnutrition, dyshormonia and whole body Wasting diseasess are relevant.Chinese medicine then thinks, caused by this disease is mainly due to deficiency of the liver and kindey, deficiency of both QI and blood.Geneogenous few white Head, how relevant with heredity, it is difficult to treat.And teen-ager leukotrichia posteriority, except according in addition to etiological treatment, nutrition also should be strengthened.
Teenager is in the green, preponderance of YANG QI, if pathogenic heat human blood.Decoct consumption cloudy liquid, then beard and hair cervical carcinoma with cachexia and early white.As ZHANG Cong-zheng ?《Confucian's Duties to Their Parents》In described:" to such as young.Send out early fall in vain, or white scales person, this heat in blood and too ".Nutrient blood deficiency-heat causes early white Person is more common in teenager, is in grey more, first has a small amount of poliosis, gradually increase later, black and white is mutually miscellaneous, very then poliosis can account for its poliosis All 70%~80% about of hair.Typically many no conscious symptons, some companions see that scalp is scorching hot, prurituss, have white scales to come off or see Fidgets due to deficiency is uneasy.Insomnia and dreamful sleep, memory is not good.Red tongue, the rapid pulse or symptom such as count accurately.
At present the method for the treatment of early whitening of beard and hair adopts Western medicine or external used medicine mostly, and Chinese medicine for teen-ager leukotrichia treatment its Real more efficient, external used medicine belongs to cures the symptoms, not the disease, Western medicine instant effect but root can not be removed, often there is showing of Relapse rate As.
Content of the invention
It is an object of the invention to provide a kind of can significantly slow teen-ager leukotrichia symptom, the health level of lifting body, removal The scorching Chinese medicine composition of body.
The present invention is achieved through the following technical solutions:A kind of Chinese medicine composition for treating teen-ager leukotrichia, by weight, Including:Fructus Mori 4-17 part, Radix Rehmanniae 4-12 part, Radix Paeoniae Rubra 3-16 part, Folium Mori 5-15 part, Cortex Moutan 7-21 part, Flos Chrysanthemi 5-18 part, the Radix Polygoni Multiflori 15-30 part.
A kind of crude drug pharmacology of Chinese medicine composition for treating teen-ager leukotrichia of the present invention:
Fructus Mori:Cold in nature, sweet in the mouth, acid.Thoughts of returning home warp, Liver Channel, kidney channel.Enrich blood YIN nourishing, fluid dryness.Belong to qi-restoratives medicine subordinate classification Hematonic.
The Radix Rehmanniae:Cold in nature, sweet in the mouth.Thoughts of returning home warp, Liver Channel, kidney channel.Clearing away heat and cooling blood, yin nourishing, promote the production of body fluid.Belong to antipyretic subordinate classification Heat removing and blood cooling medicine.
Radix Paeoniae Rubra:Cold nature, bitter in the mouth.Return liver warp, spleen channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Belong to the heat clearing away of antipyretic subordinate classification Blood-cooling drugs.
Folium Mori:Cold in nature, sweet in the mouth, hardship.Return lung warp, Liver Channel.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.Belong to diaphoretic medicine subordinate The pungent and cold medicine for relieving the exterior syndrome of classification.Cortex Moutan:Cold nature, bitter in the mouth, pungent.Thoughts of returning home warp, Liver Channel, kidney channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Belong to clear The heat removing and blood cooling medicine of medicine of a warm nature subordinate classification.
Flos Chrysanthemi:Cold nature, sweet in the mouth, hardship.Return lung warp, Liver Channel.Scattered wind heat clearing away, flat liver improving eyesight.Belong to diaphoretic medicine subordinate classification Pungent and cold medicine for relieving the exterior syndrome.
The Radix Polygoni Multiflori:Warm in nature, bitter in the mouth, sweet, puckery.Return liver warp, kidney channel, heart channel.Removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.Belong to lower point of purgatives medicine The laxative drug of class.
The preparation method of medicine of the present invention, comprises the following steps:
(1)Represented with weight portion, weigh Fructus Mori 4-17 part, Radix Rehmanniae 4-12 part, Radix Paeoniae Rubra 3-16 part, Folium Mori 5-15 part, Cortex Moutan 7- 21 parts, Flos Chrysanthemi 5-18 part, Radix Polygoni Multiflori 15-30 part;
(2)By above-mentioned whole raw material of Chinese medicine medicines, clear water or pure water is used in advance to soak 30 minutes, water consumption for immersion is 0.9 ~ 1.1L;
(3)The liquid medicine of the raw material of Chinese medicine medicine after soaking and its immersion is added in decocting container, adds a cover and jointly decoct;
(4)So that decocting container herb liquid is seethed with excitement with high heat, reuse slow fire and boil, need to stir when boiling medicine 2 ~ 3 times;
(5)After the completion of decoction, plus proper amount of clear water or pure water did not had medicine, carried out second decoction, decocted duration and degree of heating method ibid;
(6)Leach medicinal liquid, obtained medicinal liquid is endo-medicine.
For optimizing the effect of drugs of medicine, further, 10 parts of described Fructus Mori, 10 parts of the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, Folium Mori 12 Part, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori.
Further, in order to improve extraction effect of drugs, present invention additionally comprises:Radix Rehmanniae 3-23 part, Fructus Viticises 5-25 part.
Further, described Chinese medicine composition includes the raw material of following weight portion:
10 parts of Fructus Mori, 10 parts of the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 12 parts of Folium Mori, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori, Radix Rehmanniae 20 Part, 10 parts of Fructus Viticises.
Further, described Fructus Mori selects morus notabili or morus bombycis.
The Chinese medicine composition of the present invention does not have untoward reaction in use, and the treatment to teen-ager leukotrichia has significantly Effect, the medicine material of selection does not have toxic and side effects from each other, and slight and severe teen-ager leukotrichia patient can use, applicable model Enclose wide, strengthen the hair quality of hair, eliminate the fire of moxibustion of body, improve the mental status.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, but embodiments of the present invention not limited to this, Without departing from the idea case in the present invention described above, according to ordinary skill knowledge and customary means, make various replacing Change and change, all should be included within the scope of the invention.
Embodiment 1:
A kind of Chinese medicine composition for treating teen-ager leukotrichia described in the present embodiment, by weight, including:Fructus Mori 4-17 part, Radix Rehmanniae 4-12 part, Radix Paeoniae Rubra 3-16 part, Folium Mori 5-15 part, Cortex Moutan 7-21 part, Flos Chrysanthemi 5-18 part, Radix Polygoni Multiflori 15-30 part.
The preparation method of medicine of the present invention, comprises the following steps:
(1)Represented with weight portion, weigh Fructus Mori 4-17 part, Radix Rehmanniae 4-12 part, Radix Paeoniae Rubra 3-16 part, Folium Mori 5-15 part, Cortex Moutan 7- 21 parts, Flos Chrysanthemi 5-18 part, Radix Polygoni Multiflori 15-30 part;
(2)By above-mentioned whole raw material of Chinese medicine medicines, clear water or pure water is used in advance to soak 30 minutes, water consumption for immersion is 0.9 ~ 1.1L;
(3)The liquid medicine of the raw material of Chinese medicine medicine after soaking and its immersion is added in decocting container, adds a cover and jointly decoct;
(4)So that decocting container herb liquid is seethed with excitement with high heat, reuse slow fire and boil, need to stir when boiling medicine 2 ~ 3 times;
(5)After the completion of decoction, plus proper amount of clear water or pure water did not had medicine, carried out second decoction, decocted duration and degree of heating method ibid;
(6)Leach medicinal liquid, obtained medicinal liquid is endo-medicine.
Embodiment 2:
The Chinese medicine composition of teen-ager leukotrichia is treated described in the present embodiment, by weight, including:10 parts of Fructus Mori, 10 parts of the Radix Rehmanniae, red 15 parts of Chinese herbaceous peony, 12 parts of Folium Mori, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori.
Embodiment 3:
The present embodiment, on the basis of above-described embodiment, further, also includes Radix Rehmanniae 3-23 part, Fructus Viticises 5-25 part.I.e. The Chinese medicine composition of this treatment teen-ager leukotrichia, by weight, including:10 parts of Fructus Mori, 10 parts of the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, Folium Mori 12 Part, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori, 20 parts of Radix Rehmanniae, 10 parts of Fructus Viticises
The other parts of the present embodiment are same as the previously described embodiments, repeat no more.
Embodiment 4:
The present embodiment provides the toxicology test of the Chinese medicine composition of this treatment teen-ager leukotrichia, specific as follows:
Acute toxicity test:
Experimental observation, because measuring LD50, therefore has carried out the mensure of maximum dosage-feeding.Chinese medicine composition prepared by embodiment 1 Thing is dissolved in sterile saline, is configured to solution gavage mice, and result shows, raw with medicine maximum administration concentration 9.65 Medicine/ml, maximum administered volume 50ml/kg was administered twice to mouse stomach in 24 hours, and mice maximum dosage-feeding is 763.25g Crude drug/kg, untoward reaction and death in animal, anatomic observation each internal organs no abnormality seen.
Long term toxicity test:
SD rat 80 is applied in this test, and Chinese medicine composition prepared by embodiment 1 is dissolved in sterile saline, is configured to Solution gavage, if matched group and 24g, 35g, 49g crude drug/kg dosage group, continuous gavage is administered 12 weeks, observes the Chinese medicine of the present invention The impact to animal indices for the compositionss.Result of the test shows, successive administration 12 weeks, and the Chinese medicine composition of the present invention is to rat Body weight, food ration, peripheral hemogram, clotting time, electrocardiogram, organ index etc. all have no significant effect;Blood biochemical ten binomial Index determining result, 12 weeks low dose group BiLi values of administration are higher than matched group(P<0.05);Low dose group, middle dose group TP value are high In matched group(P<0.05), but all within normal physiologic range, other indexs compare no significant difference with matched group.Convalescent period Each administration group indices measured value compares equal no significant difference with matched group.Each group each internal organs gross examination of skeletal muscle no abnormality seen.
The using method of medicine of the present invention:Directly take orally.
Teen-ager leukotrichia diagnostic criteria:
Slight teen-ager leukotrichia:A small amount of poliosis are had, hair is with a small amount of dandruff in hair.
Moderate teen-ager leukotrichia:Poliosis amount is more, and black and white is mixed, dry hair, with the symptom of scalp itch.
Severe teen-ager leukotrichia:Poliosis rate reaches 70% about, or even visible hair sparse comes off, patient can with seeing dizziness and blurred vision, Hiccough and deaf, soreness of the waist and knees, nocturia frequency, red tongue or secretly fat, the deficient and stringy pulse or symptom such as count accurately.
It is directed to the clinical statisticses data of various teen-ager leukotrichia patients using medicine of the present invention:
Through the Clinical practice of 200 patients, wherein male patient 114, female patient 86, medication age object 14-23 year.Wherein Minimum 14 years old, maximum 23 years old, 18 years old mean age;Slight teen-ager leukotrichia 32, moderate teen-ager leukotrichia 77, severe teen-ager leukotrichia 41.
Model case:
1st, Zhang, 19 years old, man, when 18 years old, serious disease one, sapped one's vitality afterwards, and internal organs void exhausts, with grey hair gradually to all white Send out, have concurrently sparse come off, the very thin tarnish of hair, the method before having been used up external treatment is treated, but poor effect, Prescription using the embodiment of the present invention 2 takes 3 courses for the treatment of orally, and hair quality is remarkably reinforced, and no longer alopecia is shaved one's head, and hair becomes black by greyish white Color.
2nd, Wang, 18 years old, man, senior middle school find in period oneself to turn white more and more, scalp itch more very, as avenged more than dandruff Flower, that grabs is easily de-, and hair is dried matt, the scattered alopecia of head, did one's utmost later adjustment work and rest and mental pressure, but effect is micro- It is micro-, and the prescription using the embodiment of the present invention 3 takes 5 courses for the treatment of orally, and depilation phenomenon disappears, and poliosis significantly reduce, the dandruff and The symptom of prurituss also eliminates.
3rd, Liu, 16 years old, female, in the short time, hair bleaches in a large number, many spiritednesses stimulating factor before disease, vexed with fullness in the chest and hypochondrium Distending pain, susceptible to lose temper due to restlessness, sighing frequently, dark tongue quality or have petechia, the symptom such as stringy and hesitant pulse, things is created and is weary of sense, using this The prescription of inventive embodiments 2 takes 5 courses for the treatment of, hair color blackening orally, and the mental status is obviously improved, the dandruff and scalp itch Symptom substantially eliminates, and mental state is improved good.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that:Not Multiple changes, modification, replacement and modification can be carried out to these embodiments under the principle of the disengaging present invention and objective, the present invention's Scope is limited by claim and its equivalent.

Claims (5)

1. a kind of Chinese medicine composition for treating teen-ager leukotrichia is it is characterised in that by weight, including:Fructus Mori 4-17 part, Radix Rehmanniae 4-12 part, Radix Paeoniae Rubra 3-16 part, Folium Mori 5-15 part, Cortex Moutan 7-21 part, Flos Chrysanthemi 5-18 part, Radix Polygoni Multiflori 15-30 part.
2. a kind of Chinese medicine composition for treating teen-ager leukotrichia according to claim 1 is it is characterised in that described Fructus Mori 10 parts, 10 parts of the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 12 parts of Folium Mori, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori.
3. a kind of Chinese medicine composition for treating teen-ager leukotrichia according to claim 1 and 2 is it is characterised in that by weight Part meter, also includes:Radix Rehmanniae 3-23 part, Fructus Viticises 5-25 part.
4. a kind of Chinese medicine composition for treating teen-ager leukotrichia according to claim 3 is it is characterised in that this Chinese medicine composition Thing includes the raw material of following weight portion:
10 parts of Fructus Mori, 10 parts of the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 12 parts of Folium Mori, 16 parts of Cortex Moutan, 13 parts of Flos Chrysanthemi, 21 parts of the Radix Polygoni Multiflori, Radix Rehmanniae 20 Part, 10 parts of Fructus Viticises.
5. a kind of Chinese medicine composition for treating teen-ager leukotrichia according to claim 1 and 2 is it is characterised in that described Mulberry Mulberry selects morus notabili or morus bombycis.
CN201610975228.1A 2016-11-07 2016-11-07 Traditional Chinese medicine compound for treating premature white hair Withdrawn CN106389646A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421117A (en) * 2016-11-07 2017-02-22 成都泠汐尚品科技有限公司 Traditional Chinese medicine composition for curing premature graying of hair

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189592A (en) * 2014-09-13 2014-12-10 吕银兰 Traditional Chinese medicine preparation for treating teenager white hair
CN105287873A (en) * 2014-07-30 2016-02-03 徐长春 Formula for premature graying treatment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287873A (en) * 2014-07-30 2016-02-03 徐长春 Formula for premature graying treatment
CN104189592A (en) * 2014-09-13 2014-12-10 吕银兰 Traditional Chinese medicine preparation for treating teenager white hair

Non-Patent Citations (1)

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Title
刘利 等: "《古今桑系列验方大全》", 31 October 2016, 中国农业科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421117A (en) * 2016-11-07 2017-02-22 成都泠汐尚品科技有限公司 Traditional Chinese medicine composition for curing premature graying of hair

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