CN104056196A - Traditional Chinese medicine composition for treating bradycardia - Google Patents
Traditional Chinese medicine composition for treating bradycardia Download PDFInfo
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- CN104056196A CN104056196A CN201410291683.0A CN201410291683A CN104056196A CN 104056196 A CN104056196 A CN 104056196A CN 201410291683 A CN201410291683 A CN 201410291683A CN 104056196 A CN104056196 A CN 104056196A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating bradycardia, which comprises the following traditional Chinese medicine materials in parts by weight: 10-40 parts of radix astragali seu hedysari, 5-20 parts of peach kernels, 10-30 parts of radix angelicae sinensis, 10-40 parts of radix codonopsis, 5-20 parts of flos carthami, 10-40 parts of radix salviae miltiorrhizae, 5-25 parts of radix curcumae, 5-20 parts of radix platycodonis, 10-30 parts of rhizoma ligustici, 5-20 parts of rhizoma pinelliae, 10-40 parts of caulis spatholobi, 5-20 parts of cortex cinnamomi, 15-35 parts of fructus trichosanthis, 5-20 parts of fructus aurantii immaturus, 10-30 parts of rhizoma atractylodis macrocephalae, 5-20 parts of radix paeoniae rubra, 10-30 parts of radix puerariae, and 5-20 parts of rhizoma cyperi, 10-40 parts of bulbus lili, 10-30 parts of fructus ligustri lucidi and 5-10 parts of radix glycyrrhiza. The traditional Chinese medicine composition has the effects of nourishing liver and kidney,reinforcing qi and nourishing blood, promoting blood circulation to remove meridian obstruction, removing blood stasis and reliving pain, removing cardiopyrexia and tranquilization, and is obvious in curative effect and reliable in efficacy when being used for treating bradycardia.
Description
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind ofly treat bradycardic Chinese medicine composition.
Background technology
Bradycardia is ARR a kind of pathological changes, is because of heart collecting moving arhythmicity, and under normal circumstances, the impulsion of heartbeat originates from sinuatrial node, its rhythm and pace of moving things rule, and heart rate is within the scope of 60-100 beat/min; Impulsion first propagates into two atrium, then passes through normal propagation approach in atrioventricular node and ventricle, with certain speed, spreads two ventricles, is called normal sinus rhythm.All cardiomotilitys that departs from this normal cardiac rhythm all belong to arrhythmia; Common are sinus bradycardia, early rich, paroxysmal tachycardia, atrioventricular block, sinuatrial node conduction block, preexcitation syndrome etc.Its clinical manifestation is: cardiopalmus, palpitation with a distress feeling, pareordia discomfort, sensation of oppression over the chest with shortness of breath, spiritlessness and weakness, dizziness, aversion to cold and cold limbs, pale tongue, tongue are white fat or greasy in vain, and tongue side tooth prints, and deep-thready pulse is irregular; Feel oppressed in severe patient ambition or twinge, dull pain, cannot not breathe hard continuously, 40 beats/min of left and right of heart rate, and uneasy sleeping at night, frightened cautious, suppresses awakely in sleeping, have dead sense frequently, nervous, pale complexion, inappetence, vomiting and nausea or diarrhoea, dizzy wish are fallen forward, and tired unable, speech is without god.Even not serious when primary disease starts, also may develop into serious arrhythmia, so very important.Modern medicine is for clinical a certain symptom treatment, live toward falling flat, the most effective Therapeutic Method is artificial cardiac pacemaker implantation at present, and expense is higher, and pacemaker settles postoperative existence that the deficiency of hematoma and the more common severe complication such as infection, loose electrode placement easily occurs.
Motherland's medical science thinks that bradycardic etiology and pathogenesis is that decline of the fire from the gate of life, deficiency of heart-YANG and kidney-YANG, hypoactivity of spleen-YANG are this, and the stagnation of QI, blood stasis, the turbid strongly fragrant resistance of expectorant are mark, belong to the card of deficiency in origin and excess in superficiality.
According to theory of Chinese medical science, for bradycardic pathogeny, adopt the method for the treatment of of nourishing the liver and kidney, benefiting QI and nourishing blood, promoting blood circulation to remove obstruction in the collateral, stasis-dispelling and pain-killing, clearing away heart-fire for tranquillization, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome, in prior art, treat the deficiency that bradycardia exists, the invention provides a kind of prepare easy, cost is low, the bradycardic Chinese medicine composition for the treatment of evident in efficacy, that have no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind ofly treat bradycardic Chinese medicine composition, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Semen Persicae 5-20 part, Radix Angelicae Sinensis 10-30 part, Radix Codonopsis 10-40 part, Flos Carthami 5-20 part, Radix Salviae Miltiorrhizae 10-40 part, Radix Curcumae 5-25 part, Radix Platycodonis 5-20 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Pinelliae 5-20 part, Caulis Spatholobi 10-40 part, Cortex Cinnamomi 5-20 part, Fructus Trichosanthis 15-35 part, Fructus Aurantii Immaturus 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Radix Paeoniae Rubra 5-20 part, Radix Puerariae 10-30 part, Rhizoma Cyperi 5-20 part, Bulbus Lilii 10-40 part, Fructus Ligustri Lucidi 10-30 part, Radix Glycyrrhizae 5-10 part.
The preferred technical solution of the present invention is: a kind ofly treat bradycardic Chinese medicine composition, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 10 parts, Semen Persicae, 20 parts of Radix Angelicae Sinensis, 30 parts of Radix Codonopsis, 10 parts, Flos Carthami, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Curcumaes, 10 parts of Radix Platycodoniss, 20 parts of Rhizoma Chuanxiongs, 12 parts of the Rhizoma Pinelliaes, 30 parts of Caulis Spatholobis, 10 parts of Cortex Cinnamomis, 25 parts of Fructus Trichosanthis, 10 parts of Fructus Aurantii Immaturuss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Radix Paeoniae Rubra, 20 parts of Radix Puerariaes, 10 parts of Rhizoma Cyperis, 30 parts of Bulbus Liliies, 20 parts of Fructus Ligustri Lucidi, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Semen Persicae has the effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; Radix Codonopsis has the effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Flos Carthami has the effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Radix Curcumae has the effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend the effect of five kinds of over strain; Rhizoma Chuanxiong has the effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through the effect of dredging collateral; Cortex Cinnamomi have mend that fire is supporing yang, the effect of dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow; Fructus Trichosanthis has clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes the effect of laxation; Fructus Aurantii Immaturus has the effect of the loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Paeoniae Rubra has the effect of clearing away heat and cooling blood, eliminating stasis to stop pain; Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Rhizoma Cyperi has the effect of liver-smoothing, qi-regulating, resolving depression pain relieving; Bulbus Lilii has the effect of nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization, nourishing essence-blood; Fructus Ligustri Lucidi has the effect that nourishing the liver and kidney, tonifying YIN nourish blood; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether the effect of nourishing the liver and kidney, benefiting QI and nourishing blood, promoting blood circulation to remove obstruction in the collateral, stasis-dispelling and pain-killing, clearing away heart-fire for tranquillization, and bradycardic treatment is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 93%, cure rate 68%.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a bradycardic Chinese medicine composition, its raw material of Chinese medicine and weight proportion are: Radix Astragali 30g, Semen Persicae 10g, Radix Angelicae Sinensis 20g, Radix Codonopsis 30g, Flos Carthami 10g, Radix Salviae Miltiorrhizae 30g, Radix Curcumae 15g, Radix Platycodonis 10g, Rhizoma Chuanxiong 20g, Rhizoma Pinelliae 12g, Caulis Spatholobi 30g, Cortex Cinnamomi 10g, Fructus Trichosanthis 25g, Fructus Aurantii Immaturus 10g, Rhizoma Atractylodis Macrocephalae 20g, Radix Paeoniae Rubra 12g, Radix Puerariae 20g, Rhizoma Cyperi 10g, Bulbus Lilii 30g, Fructus Ligustri Lucidi 20g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a bradycardic Chinese medicine composition, its raw material of Chinese medicine and weight proportion are: Radix Astragali 15g, Semen Persicae 20g, Radix Angelicae Sinensis 10g, Radix Codonopsis 40g, Flos Carthami 5g, Radix Salviae Miltiorrhizae 35g, Radix Curcumae 10g, Radix Platycodonis 20g, Rhizoma Chuanxiong 15g, Rhizoma Pinelliae 20g, Caulis Spatholobi 10g, Cortex Cinnamomi 15g, Fructus Trichosanthis 20g, Fructus Aurantii Immaturus 5g, Rhizoma Atractylodis Macrocephalae 30g, Radix Paeoniae Rubra 10g, Radix Puerariae 25g, Rhizoma Cyperi 5g, Bulbus Lilii 40g, Fructus Ligustri Lucidi 25g, Radix Glycyrrhizae 8g.
Embodiment 3
Treat a bradycardic Chinese medicine composition, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Semen Persicae 5g, Radix Angelicae Sinensis 15g, Radix Codonopsis 25g, Flos Carthami 15g, Radix Salviae Miltiorrhizae 10g, Radix Curcumae 25g, Radix Platycodonis 12g, Rhizoma Chuanxiong 25g, Rhizoma Pinelliae 10g, Caulis Spatholobi 35g, Cortex Cinnamomi 20g, Fructus Trichosanthis 15g, Fructus Aurantii Immaturus 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Paeoniae Rubra 15g, Radix Puerariae 10g, Rhizoma Cyperi 20g, Bulbus Lilii 10g, Fructus Ligustri Lucidi 30g, Radix Glycyrrhizae 7g.
Embodiment 4
Treat a bradycardic Chinese medicine composition, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Semen Persicae 15g, Radix Angelicae Sinensis 25g, Radix Codonopsis 15g, Flos Carthami 12g, Radix Salviae Miltiorrhizae 25g, Radix Curcumae 20g, Radix Platycodonis 5g, Rhizoma Chuanxiong 10g, Rhizoma Pinelliae 15g, Caulis Spatholobi 25g, Cortex Cinnamomi 5g, Fructus Trichosanthis 30g, Fructus Aurantii Immaturus 12g, Rhizoma Atractylodis Macrocephalae 15g, Radix Paeoniae Rubra 20g, Radix Puerariae 15g, Rhizoma Cyperi 12g, Bulbus Lilii 25g, Fructus Ligustri Lucidi 10g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a bradycardic Chinese medicine composition, its raw material of Chinese medicine and weight proportion are: Radix Astragali 40g, Semen Persicae 12g, Radix Angelicae Sinensis 30g, Radix Codonopsis 10g, Flos Carthami 20g, Radix Salviae Miltiorrhizae 40g, Radix Curcumae 5g, Radix Platycodonis 15g, Rhizoma Chuanxiong 30g, Rhizoma Pinelliae 5g, Caulis Spatholobi 40g, Cortex Cinnamomi 12g, Fructus Trichosanthis 40g, Fructus Aurantii Immaturus 15g, Rhizoma Atractylodis Macrocephalae 25g, Radix Paeoniae Rubra 5g, Radix Puerariae 30g, Rhizoma Cyperi 15g, Bulbus Lilii 35g, Fructus Ligustri Lucidi 15g, Radix Glycyrrhizae 10g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15~20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20~30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15~20 minutes.Decoct extracting juice twice, merge.
The present invention treats bradycardic Chinese medicine composition with given a kind of of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 examples, male 54 examples, female's 46 examples, 40~75 years old age.
Two, clinical manifestation:
Cardiopalmus, palpitation with a distress feeling, pareordia discomfort, sensation of oppression over the chest with shortness of breath, spiritlessness and weakness, dizziness, aversion to cold and cold limbs, pale tongue, tongue are white fat or greasy in vain, and tongue side tooth prints, and deep-thready pulse is irregular; Feel oppressed in severe patient ambition or twinge, dull pain, cannot not breathe hard continuously, 40 beats/min of left and right of heart rate, and uneasy sleeping at night, frightened cautious, suppresses awakely in sleeping, have dead sense frequently, nervous, pale complexion, inappetence, vomiting and nausea or diarrhoea, dizzy wish are fallen forward, and tired unable, speech is without god.
Three, usage and dosage: during clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, minute morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Avoid cold and uncooked food during the treatment thing of pungent stimulation.
Four, criterion of therapeutical effect:
(1) cure: symptom, sign all disappear, and each coherence check index such as electrocardiogram is completely normal;
(2) effective: symptom, sign disappear substantially, each coherence check index normal such as electrocardiogram;
(3) effective: symptom, sign take a turn for the better to some extent, and each coherence check index such as electrocardiogram is improved;
(4) invalid: the coherence check indexs such as symptom, sign and electrocardiogram are without any change, and symptom is as front.
Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, recovery from illness 68 examples, follow up a case by regular visits to and have no recurrence; Effective 16 examples, effective 9 examples, invalid 7 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Yao, man, 53 years old.Sensation of oppression over the chest with shortness of breath, more than 2 years, increased the weight of before ten days, thorn uncomfortable in chest, and sore throat, backache, pale complexion, dripping sweat, rapid breathing, breathes 30 beats/min, 35 beats/min of hearts rate, hear sounds is faint, arrhythmia.Be diagnosed as: bradycardia.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, sensation of oppression over the chest with shortness of breath is greatly alleviated, and sore throat, backache alleviate; Continue to take 2 courses for the treatment of, all diseases all disappear, and it is normal that heart rate recovers, recovery from illness.After half a year, follow up a case by regular visits to without recurrence.
Case 2:
Normal certain, female, 47 years old.Patient started to occur bradycardia before 1 year, and heart rate ordinary wave moves between 38~50 beats/min, often occurred to have palpitation, and particularly phenomenon uncomfortable in chest, once had no improvement in hospitalize.When medical, heart rate is 40 beats/min, lusterless complexion, fatigue and weakness, white and thin fur, deep and weak pulse.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, heart rate is 52 beats/min, nervous, remarkable alleviation uncomfortable in chest; Continue to take 3 courses for the treatment of, heart rate has risen to 68 beats/min, and nervous, symptom uncomfortable in chest disappears completely, recovery from illness.Follow up a case by regular visits to 1 year without recurrence.
Claims (2)
1. the bradycardic Chinese medicine composition for the treatment of, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Semen Persicae 5-20 part, Radix Angelicae Sinensis 10-30 part, Radix Codonopsis 10-40 part, Flos Carthami 5-20 part, Radix Salviae Miltiorrhizae 10-40 part, Radix Curcumae 5-25 part, Radix Platycodonis 5-20 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Pinelliae 5-20 part, Caulis Spatholobi 10-40 part, Cortex Cinnamomi 5-20 part, Fructus Trichosanthis 15-35 part, Fructus Aurantii Immaturus 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Radix Paeoniae Rubra 5-20 part, Radix Puerariae 10-30 part, Rhizoma Cyperi 5-20 part, Bulbus Lilii 10-40 part, Fructus Ligustri Lucidi 10-30 part, Radix Glycyrrhizae 5-10 part.
2. a kind ofly according to claim 1 treat bradycardic Chinese medicine composition, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 10 parts, Semen Persicae, 20 parts of Radix Angelicae Sinensis, 30 parts of Radix Codonopsis, 10 parts, Flos Carthami, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Curcumaes, 10 parts of Radix Platycodoniss, 20 parts of Rhizoma Chuanxiongs, 12 parts of the Rhizoma Pinelliaes, 30 parts of Caulis Spatholobis, 10 parts of Cortex Cinnamomis, 25 parts of Fructus Trichosanthis, 10 parts of Fructus Aurantii Immaturuss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Radix Paeoniae Rubra, 20 parts of Radix Puerariaes, 10 parts of Rhizoma Cyperis, 30 parts of Bulbus Liliies, 20 parts of Fructus Ligustri Lucidi, 6 parts, Radix Glycyrrhizae.
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Application publication date: 20140924 |