CN106377813B - 用于血液处理系统的界面检测器 - Google Patents

用于血液处理系统的界面检测器 Download PDF

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Publication number
CN106377813B
CN106377813B CN201610737388.2A CN201610737388A CN106377813B CN 106377813 B CN106377813 B CN 106377813B CN 201610737388 A CN201610737388 A CN 201610737388A CN 106377813 B CN106377813 B CN 106377813B
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light
source
optical sensor
blood
sensor system
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CN106377813A (zh
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彼得·大卫·考德尔卡
瑞安·艾略特·埃克曼
埃里克·卡尔·林德马克
卢博米尔·考德尔卡
詹姆斯·约瑟夫·厄尔迈斯
史蒂文·R·卡茨
威廉·H·科克
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Fenwal Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B13/00Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59Transmissivity
    • G01N21/5907Densitometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0415Plasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0427Platelets; Thrombocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0429Red blood cells; Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B13/00Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B04B2013/006Interface detection or monitoring of separated components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/061Sources
    • G01N2201/06113Coherent sources; lasers
    • G01N2201/0612Laser diodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0636Reflectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Centrifugal Separators (AREA)
CN201610737388.2A 2012-09-04 2013-03-14 用于血液处理系统的界面检测器 Active CN106377813B (zh)

Applications Claiming Priority (3)

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US201261696343P 2012-09-04 2012-09-04
US61/696,343 2012-09-04
CN201380046188.7A CN104602725B (zh) 2012-09-04 2013-03-14 用于血液处理系统的界面检测器

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CN106377813B true CN106377813B (zh) 2020-03-24

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CN201610737388.2A Active CN106377813B (zh) 2012-09-04 2013-03-14 用于血液处理系统的界面检测器
CN201380046188.7A Active CN104602725B (zh) 2012-09-04 2013-03-14 用于血液处理系统的界面检测器
CN202010151648.4A Active CN111494743B (zh) 2012-09-04 2013-03-14 血液处理系统和在血液处理系统内监测流体的方法

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CN202010151648.4A Active CN111494743B (zh) 2012-09-04 2013-03-14 血液处理系统和在血液处理系统内监测流体的方法

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US (3) US9594020B2 (enExample)
EP (1) EP2892587B1 (enExample)
JP (4) JP6250053B2 (enExample)
CN (3) CN106377813B (enExample)
AU (2) AU2013313352B2 (enExample)
IN (1) IN2015DN01424A (enExample)
WO (1) WO2014039091A1 (enExample)

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EP2892587B1 (en) 2012-09-04 2024-07-03 Fenwal, Inc. Interface detector for blood processing system
WO2016204533A1 (ko) 2015-06-16 2016-12-22 (주)타스컴 생체 측정기
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CN106111356B (zh) * 2016-06-29 2019-03-19 四川南格尔生物科技有限公司 一种探测装置及探测方法
CN109253988A (zh) * 2016-08-25 2019-01-22 任文利 一种血液浓度检测装置
CN109922842A (zh) 2016-09-16 2019-06-21 汾沃有限公司 采用离心和旋转膜分离技术的血液分离系统和方法
EP3372259B1 (en) 2017-03-07 2022-11-23 Fenwal, Inc. System and methods for separating blood under conditions of reduced plasma clarity
US10561784B2 (en) * 2017-05-31 2020-02-18 Fenwal, Inc. Stationary optical monitoring system for blood processing system
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EP4494668A3 (en) 2017-12-22 2025-04-30 Fenwal, Inc. Convertible fluid processing assemblies
US10893829B2 (en) 2018-04-13 2021-01-19 Fenwal, Inc. Optical detection and measurement of hematocrit and free hemoglobin concentration
US10890524B2 (en) * 2018-06-05 2021-01-12 Fenwal, Inc. Discerning between the presence of red blood cells and free hemoglobin in a biological fluid
US11137344B2 (en) 2018-11-28 2021-10-05 Fenwal, Inc. Optical mixing of fluids
EP3705147B1 (en) 2019-03-05 2024-11-06 Fenwal, Inc. Collection, genome editing, and washing of t-cell lymphocytes
US11311823B2 (en) 2019-03-05 2022-04-26 Fenwal, Inc. Collection of mononuclear cells and peripheral blood stem cells
US11484891B2 (en) 2019-05-23 2022-11-01 Fenwal, Inc. Adjustment of target interface location between separated fluid components in a centrifuge
EP4566642A1 (en) 2019-05-23 2025-06-11 Fenwal, Inc. Centrifugal separation and collection of red blood cells or both red blood cells and plasma
CN112495596B (zh) 2019-09-16 2022-07-26 汾沃有限公司 用于血液成分的分离和收集的算法的动态调整
EP3834858A1 (en) 2019-12-12 2021-06-16 Fenwal, Inc. Systems enabling alternative approaches to therapeutic red blood cell exchange and/or therapeutic plasma exchange
IT202000006712A1 (it) * 2020-03-31 2021-10-01 Medica S P A Sistema per misurare parametri intrinseci di un fluido organico circolante in un condotto
CN114306788A (zh) * 2020-09-30 2022-04-12 汾沃有限公司 检测组件的光源的位置的调节
US12313441B2 (en) 2021-01-29 2025-05-27 Fenwal, Inc. Automated splitting of a fluid into uneven volumes
US11898967B2 (en) 2021-02-02 2024-02-13 Fenwal, Inc. Predicting malfunction and failure of centrifuge umbilicus
EP4075119B1 (en) 2021-04-15 2025-11-12 Fenwal, Inc. Adjustment of the thickness of a biological fluid being monitored by an optical detection assembly
CN117259035B (zh) * 2023-09-08 2024-09-06 江苏赛德力制药机械制造有限公司 一种基于机器视觉的离心机自动控制系统及方法
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CN106377813A (zh) 2017-02-08
WO2014039091A1 (en) 2014-03-13
AU2013313352B2 (en) 2017-03-02
JP2015530156A (ja) 2015-10-15
JP2022028921A (ja) 2022-02-16
AU2013313352A1 (en) 2015-04-09
JP2018086264A (ja) 2018-06-07
CN104602725B (zh) 2017-04-26
EP2892587B1 (en) 2024-07-03
EP2892587A1 (en) 2015-07-15
IN2015DN01424A (enExample) 2015-07-03
US20190120761A1 (en) 2019-04-25
JP6989579B2 (ja) 2022-01-05
US10768107B2 (en) 2020-09-08
JP2020036930A (ja) 2020-03-12
CN104602725A (zh) 2015-05-06
JP6250053B2 (ja) 2017-12-20
US10209185B2 (en) 2019-02-19
AU2017201732A1 (en) 2017-03-30
US20170131203A1 (en) 2017-05-11
AU2017201732B2 (en) 2018-11-01
US9594020B2 (en) 2017-03-14
JP7337137B2 (ja) 2023-09-01
CN111494743A (zh) 2020-08-07
EP2892587C0 (en) 2024-07-03
CN111494743B (zh) 2023-08-22
US20150219558A1 (en) 2015-08-06

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