CN106376925A - Amomum tsao-ko-carrot powder and application thereof - Google Patents

Amomum tsao-ko-carrot powder and application thereof Download PDF

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Publication number
CN106376925A
CN106376925A CN201610787145.XA CN201610787145A CN106376925A CN 106376925 A CN106376925 A CN 106376925A CN 201610787145 A CN201610787145 A CN 201610787145A CN 106376925 A CN106376925 A CN 106376925A
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China
Prior art keywords
tsaoko
carrot powder
amomum tsao
mesh sieve
powder
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Pending
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CN201610787145.XA
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Chinese (zh)
Inventor
叶亚东
路易斯伊格纳罗
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CHANGZHOU ADAM BIOTECH Inc
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CHANGZHOU ADAM BIOTECH Inc
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Priority to CN201610787145.XA priority Critical patent/CN106376925A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an amomum tsao-ko-carrot powder, and in particular, relates to the field of preparation of amomum tsao-ko-carrot powder. The amomum tsao-ko-carrot powder is composed of amomum tsao-ko and radish peel. The preparation method comprises the following steps: (1) heating the amomum tsao-ko, baking and stir-frying with an iron pan, or heating for 2 minutes with a microwave oven, crushing, allowing to pass through a 100-mesh sieve, circularly crushing, and allowing to pass through the 100-mesh sieve; (2) roasting the radish peel to be dried in a drying oven, crushing, allowing to pass through the 100-mesh sieve, circularly crushing, and allowing to pass through the 100-mesh sieve; and (3) mixing the amomum tsao-ko powder and the radish peel powder according to the proportion of 2:1, adding into a three-dimensional stirrer, stirring for 20 minutes, and then granulating by a granulator. The granulated amomum tsao-ko-carrot powder can be directly poured into a bag with each bag of 5 grams; the granulated amomum tsao-ko-carrot powder also can be made into effervescent tablets with each tablet of 1.2 grams; or the granulated amomum tsao-ko-carrot powder is tabletted into tablets with each tablet of 0.6 gram. The amomum tsao-ko-carrot powder is used for rapid ventilation after surgery and is safe and effective.

Description

A kind of tsaoko carrot powder and application
Technical field
The present invention relates to field of food is and in particular to a kind of preparation field of tsaoko carrot powder.
Background technology
Postoperative ventilation is conducive to the recovery of abdominal operation Intestinal Mucosal Injury in Patients Undergoing function, is the important step of postoperative rehabilitation, otherwise, easily Cause functional disturbances of gastrointestinal tract, cause complication, such as postoperative abdominal distention, stomachache, delayed exhaust defecation, nausea, vomiting, very then intestines stick Company, enteroparalysis, intestinal obstruction etc..For these clinical manifestations, the passive way such as fasting and gastrointestinal decompression is generally adopted to wait stomach and intestine The recovery of function, even needs second operation when serious, brings a series of unnecessary miseries and wound to patient.
At present, treatment by Chinese herbs is another important means of postoperative ventilation, and Chinese medicine ventilation not only can assist upper gastrointestinal work( The recovery of energy, and the generation of postoperative complications can be significantly reduced.However, as the saying goes, it is three points of poison of medicine.In treatment by Chinese herbs Cheng Zhong, substantial amounts of Chinese medicine can produce toxic and side effect unavoidably.Therefore, if it is understood by the inventors that solved using the preparation of integration of drinking and medicinal herbs Certainly the problem of postoperative ventilation, will be safe and effective method.
Tsaoko, Zingiber herbaceos perennial, is a kind of important flavouring.Meanwhile, tsaoko taste is pungent, warm in nature;Returns spleen, stomach Warp;Virtue is strong dry scattered;There are eliminating dampness middle benefit gas, ward off effect of dirty preventing malaria;Cure mainly chest diaphragm feeling of fullness, coldness and pain in the epigastrium, n and V, have loose bowels down Dysentery, dyspepsia, cholera, pestilence, malignant malaria.It is used as medicine and cures mainly stagnation of cold-damp taste, abdominal distension pain is vomitted inverse, the greasy veins is sliding of tongue, and eliminating phlegm cuts Cruel, may be used to control the malaria of cold-dampness victory partially, and the miasma caused by foul damp evil is cruel.Modern pharmacological research finds, tsaoko has ventilation Effect, drinks that tsaoko is to boil water to be can be used for ventilating after Appendectomy.
Ancient times have:" radish lists, city under doctor;Winter eats the radish summer and eats ginger, throughout the year ensure public security health " etc. saying.Radish is originally Body is nutritious, has edible, medical value well.The nutritive value of radish skin exceedes the part of radish meat.According to trophic analysis, The Vitamin C content of radish skin is about 2 times of pulp;Calcium content 98% is in radish intracutaneous.Radish leatherware has the work(of sharp diaphragm width intestines Effect, radish skin contains string, and water imbibition is strong, and in enteron aisle, volume easily expands, and is " full material " in enteron aisle, can add The wriggling of strong enteron aisle, thus sharp diaphragm width intestines, defaecation.Research finds, tsaoko is organically combined with radish skin, for postoperative Effect of ventilation is notable.
Content of the invention
The goal of the invention of this patent is to provide for a kind of tsaoko carrot powder, is mainly used in Post operation quick air, ventilation speed Degree is fast, and integration of drinking and medicinal herbs, safety, has no toxic side effect.
The technical scheme of this patent is a kind of tsaoko carrot powder, is made up of tsaoko and radish skin.Its preparation method, step bag Include (1) to heat described tsaoko, wherein can be roasted with iron pan, or microwave-oven-heating, after 2 minutes, is pulverized, and crosses 100 mesh sieves, follows Ring is pulverized, and crosses 100 mesh sieve;(2) by described radish skin, dry in baking box, pulverize, cross 100 mesh sieve, circulation is pulverized, after 100 mesh sieve;(3) by described tsaoko powder with and radish skin powder according to 2:1 ratio mixing, adds 3-dimensional mixer to stir 20 points Clock, then passes through granulator granulation.Tsaoko carrot powder after granulation can directly fill bag, 5 grams every bag;May be made as effervescent tablet, every 1.2 gram;Or compressing tablet, make tablet, every 0.6 gram.The tsaoko carrot powder of the present invention is used for Post operation quick air.
Beneficial effect
The present invention is a kind of tsaoko carrot powder, for postoperative ventilation.The test of inventor finds, patient takes the present invention's 40 minutes after preparation, start to ventilate (passwinding) it is thus only necessary to take once just permissible it is seen then that the present invention is evident in efficacy.And And, the present invention is made up of the material of integration of drinking and medicinal herbs, can be used as food consumption, and therefore security is good.
Specific embodiment
Embodiment 1
By tsaoko with, after microwave-oven-heating 2 minutes, pulverizing, cross 100 mesh sieves, circulation is pulverized, and crosses 100 mesh sieve;By radish Skin, dries in baking box, pulverizes, and crosses 100 mesh sieve, circulation is pulverized, after 100 mesh sieve;By above-mentioned tsaoko powder and and radish Skin powder compares 2 according to weight:1 ratio mixing, adds 3-dimensional mixer to stir 20 minutes, then passes through granulator granulation.After granulation Tsaoko carrot powder directly fill bag, 5 grams every bag.
Embodiment 2
After tsaoko iron pan is roasted, pulverize, cross 100 mesh sieves, circulation is pulverized, and crosses 100 mesh sieve;By radish skin, in baking box In dry, pulverize, cross 100 mesh sieve, circulation pulverize, after 100 mesh sieve;By above-mentioned tsaoko powder with and radish skin according to weigh Amount compares 2:1 ratio mixing, adds 3-dimensional mixer to stir 20 minutes, then passes through granulator granulation.Tsaoko radish after granulation Powder makes effervescent tablet, every 1.2 grams.
Embodiment 3
By tsaoko with, after microwave-oven-heating 2 minutes, pulverizing, cross 100 mesh sieves, circulation is pulverized, and crosses 100 mesh sieve;By radish Skin, dries in baking box, pulverizes, and crosses 100 mesh sieve, circulation is pulverized, after 100 mesh sieve;By above-mentioned tsaoko powder and and radish Skin powder compares 2 according to weight:1 ratio mixing, adds 3-dimensional mixer to stir 20 minutes, then passes through granulator granulation.After granulation Tsaoko carrot powder compressing tablet, make tablet, every 0.6 gram.
Embodiment 4
Or wash by water 150 milliliters for 5 grams, all take.Or 9 (0.6 gram every), takes with 150 milliliters of water.Take 40 After minute, start to ventilate (passwinding) it is thus only necessary to take once just permissible.
Embodiment 5
Using the end effect to Intestinal pushing function for the Intestinal pushing degree experimental evaluation tsaoko carrot powder of mouse charcoal.
Using mouse as animal subject, take 50 mouse, male and female half and half, body weight is 18-22g, is randomly divided into 6 groups:High Dosage group, middle dose group, low dose group, positive controls, model group, every group of l0 is only.Model group is according to the dosage of 0.2ml/10g Gavage physiological saline;Positive controls gavage 2.0g/kg shenling baizhu powder;It is (real that high, normal, basic dosage group gives tsaoko carrot powder respectively Apply example 1) 4.0g/kg, 2.0g/kg, 1.0g/kg gavage, successive administration 20 days.Last dose, after mouse fasting 24h, with containing 10% charcoal end suspension oral gavage, volume is 20ml/kg, and after 10min, de- disconnected cervical vertebra is put to death, and opens abdominal cavity separation mesenterium, clip Length of intestine, from pylorus, the intestinal tube of lower end to ileocecus, is surveyed as " total small intestinal length " in upper end;From pylorus to prepared Chinese ink forward position away from From as " prepared Chinese ink is in enteral advance distance ".Calculate ink progradation by following equation.Ink progradation (%)=prepared Chinese ink is in intestines Interior advance distance (cm)/small intestine total length (cm) × 100%.
Result:As table 1.Compared with model group mouse, tsaoko carrot powder basic, normal, high dosage energy conspicuousness raises mouse enteral Ink progradation (P<0.05).
The impact (means ± s) to mouse ink progradation for the table 1 tsaoko carrot powder
*p<0.05, * * p<0.01 compared with model group
Conclusion:Tsaoko carrot powder conspicuousness raises the ink progradation of mouse enteral, has the effect promoting Intestinal pushing.
Embodiment 5
Using the effect to gastric emptying for the gastric emptying experimental evaluation tsaoko carrot powder.
Using mouse as animal subject, take 50 mouse, male and female half and half, body weight is 18-22g, is randomly divided into 5 groups:High Dosage group, middle dose group, low dose group, positive controls, model group, every group of l0 is only.Model group is according to the dosage of 0.2ml/10g Gavage physiological saline;Positive controls gavage 2.0g/kg shenling baizhu powder;It is (real that high, normal, basic dosage group gives tsaoko carrot powder respectively Apply example 1) 4.0g/kg, 2.0g/kg, 1.0g/kg gavage, successive administration 20 days.Before carrying out gastric emptying experiment, mouse fasting 24h. After 30min after last dose, 0.1% methyl orange solution gavage 0.2ml, by each group sacrifice after 20min, ligature orifice of the stomach and imprison Door, detachment takes stomach, stomach is placed in small beaker, adds in 10ml distilled water, cuts off gastral cavity, gastric content is fully washed in distillation In water, adjust pH value to pour graduated centrifuge tube into 6.0-6.5 with NaHCO3 solution, 10min is centrifuged with 2000rpm, take supernatant to use 752 type spectrophotometer (420nm) colorimetrics, with distilled water zeroing, the optical density recording is methyl orange optical density in stomach.And with After 0.1% methyl orange 0.2ml adds 10ml distilled water to shake up, record its optical density as radix methyl orange optical density, and press Row formula calculates methyl orange Stomach residue rate, reflects gastric emptying speed.Methyl orange Stomach residue rate (%)=stomach methyl orange optical density/base Number methyl orange optical density × 100%.
Result:As table 2.Compared with model group mouse, tsaoko carrot powder basic, normal, high dosage energy conspicuousness reduces the first in stomach Base orange residual rate (P<0.05).
The impact (means ± s) to gastric emptying for the table 2 tsaoko carrot powder
*p<0.05, * * p<0.01 compared with model group
Conclusion:Tsaoko carrot powder energy conspicuousness reduces the methyl orange residual rate in stomach, has the effect promoting gastric emptying.

Claims (7)

1. a kind of tsaoko carrot powder it is characterised in that:It is made up of tsaoko and radish skin, by weight, tsaoko:Radish skin is 2:1.
2. the preparation method of tsaoko carrot powder according to claim 2, step includes(1)After described tsaoko is heated, pulverize, Cross 100 mesh sieves, circulation is pulverized, and crosses 100 mesh sieve;(2)By described radish skin, dry in baking box, pulverize, cross 100 mesh sieve, Circulation is pulverized, after 100 mesh sieve;(3)By described tsaoko powder with and radish skin powder according to 2:1 ratio mixing, adds 3-dimensional Mixer stirs 20 minutes, then passes through granulator granulation.
3. the tsaoko carrot powder according to claims 2 preparation method it is characterised in that:Described is heated to be iron pan roasting Fry.
4. the tsaoko carrot powder according to claims 2 preparation method it is characterised in that:Described is heated to be micro-wave oven Heating 2 minutes.
5. the tsaoko carrot powder according to claims 2 preparation method it is characterised in that:Described tsaoko carrot powder is direct Filling bag, 5 grams every bag.
6. the tsaoko carrot powder according to claims 2 preparation method it is characterised in that:Described tsaoko carrot powder is made Effervescent tablet, every 1.2 grams.
7. the tsaoko carrot powder according to claims 2 preparation method it is characterised in that:Described tsaoko carrot powder pressure Piece, makes tablet, every 0.6 gram.
CN201610787145.XA 2016-08-31 2016-08-31 Amomum tsao-ko-carrot powder and application thereof Pending CN106376925A (en)

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Application Number Priority Date Filing Date Title
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1583037A (en) * 2004-06-02 2005-02-23 车维新 Amomum tsao-ko volatile oil preparation, its preparing method and use
CN104305193A (en) * 2014-10-24 2015-01-28 云南白药天颐茶品有限公司 Food having effect of promoting intestine propulsion and preparation method of food

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1583037A (en) * 2004-06-02 2005-02-23 车维新 Amomum tsao-ko volatile oil preparation, its preparing method and use
CN104305193A (en) * 2014-10-24 2015-01-28 云南白药天颐茶品有限公司 Food having effect of promoting intestine propulsion and preparation method of food

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘政: "《143种食物健康指南》", 31 January 2012, 四川人民出版社 *
张超等整理: "《医理存真:中国中西医结合医学家苏涟教授医论及验方选编》", 31 August 2008, 云南民族出版社 *

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