CN106373475A - Manufacturing method of biological plasticized specimen capable of being assembled - Google Patents

Manufacturing method of biological plasticized specimen capable of being assembled Download PDF

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CN106373475A
CN106373475A CN201611079077.8A CN201611079077A CN106373475A CN 106373475 A CN106373475 A CN 106373475A CN 201611079077 A CN201611079077 A CN 201611079077A CN 106373475 A CN106373475 A CN 106373475A
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specimen
magnetic material
assembled
organ
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CN106373475B (en
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李懿
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/36Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for zoology
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof

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  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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Abstract

The invention relates to a manufacturing method of biological plasticized specimen capable of being assembled, and belongs to the technical field of biological plasticization. The specimen is manufactured via the steps of material selection, anticorrosion treatment, dissection, dehydration and degreasing, vacuum dipping, installation of a magnetic material, combination, solidification and conditioning. According to the manufacturing method of the invention, a real organism serves as the specimen, the general shape of the specimen is not changed, the specimen feels vivid, convenience is provided for post specimen observation, and use and operation are simple; the specimen can be dismounted and combined, the specimen can be manufactured part by part according to teaching materials or explained/learned layer by layer, convenience is provided for teaching and learning, reference is provided for making operation approaches and schemes for clinical doctors, and one specimen of the invention can realize functions of multiple other specimens; and the specimen is nontoxic, tasteless and easy to store, and can be placed in the air for a long time, and a healthy product is provided for users.

Description

A kind of can assembled biological plasticized specimen manufacture method
Technical field
The invention belongs to biological plasticized technical field and in particular to a kind of can assembled biological plasticized specimen manufacture method.
Background technology
In school, teaching, the conventional biological sample of study wherein have at present: biological plasticized specimen, dipping specimen and model mark This.
Plastifying technology is applied to field of biology the history of nearly 20 years, using plastifying technology produce biological plasticized Specimen has nontoxic, tasteless, can preserve for a long time and advantage easy to use, can be stored in the air for a long time;But single-piece plastifies The structure that specimen presents is unfavorable for, by the anatomic teaching of shallow-layer to deep layer and Students ' Learning, generally requiring several specimen and be combineding with each other Just enable.
Dipping specimen manufacturing process is simple, need to be placed in it is impossible to be exposed in the air for a long time and poisonous in preservation liquid, have Penetrating odor.It is also required to several specimen and combines just enable by the study of shallow-layer to deep layer after dipping specimen bottling.
Archetype is nonpoisonous and tasteless to be assembled, but it is not in kind, has certain deviation and real specimen between, can Certain misleading can be caused to student learning.
Content of the invention
In order to solve the above problems, the invention provides a kind of can assembled biological plasticized specimen manufacture method.
A kind of can assembled biological plasticized specimen manufacture method it is characterised in that comprising the following steps:
Step (1): selection, preservative treatment, from fur is complete, no corrupt, atraumatic biological sample, with the Fu Er of 5-10% Malin is irrigated to biological sample, makes formalin penetrate into each position of biological sample, and action venous perfusion of going forward side by side is red Blue dyestuff;
Step (2): dissect
The specimen that step (1) is handled well is cut skin according to anatomical requirements and is peeled off, and saves backup;
Step (3): dewatering and defatting and vacuum impregnation
Biological sample in step (2) is carried out dewatering and defatting and vacuum impregnation;Described dewatering and defatting: replace specimen with acetone In-house moisture and fat;Described vacuum impregnation: replace the in-house acetone of specimen with fluid silicone rubber;
Step (4): install magnetic material
The specimen that dipping is completed is taken out from silicone rubber;
Tear departmentalism organ as needed open;
According to the weight and volume of each portion organ splitting, select magnetic material;
According to the position relationship between each portion, on the premise of the correctness ensureing organ structure and integrity, magnetic material It is respectively installed to the deep layer of each portion organ contact surface, existed according to " the mutual repulsion of magnetic pole of the same name, synonyms pole is attracted each other " principle The deep layer of the contact surface of each portion organ installs magnetic material;
Step (5): combination
Each portion organ of magnetic material will be installed in step (4), combine from deep to shallow with form according to the original position of organism Together, separated with plastic sheeting between each portion organ of fractionation;
Step (6): solidification
Biological sample after step (5) is combined is solidified with silicone rubber firming agent;
Step (7): finishing
The silicone rubber of the biological sample excess surface after step (6) is solidified and the exposed plastic sheeting in each portion extraorgan go Fall, that is, complete the making of specimen.
Further, in described step (4), described magnetic material is Magnet.
Further, in described step (4), when magnetic material being installed at muscle, first raised along myofilament direction with scalpel Myofilament, forms opening, magnetic material is placed in opening, then uses glass cement bonding myofilament, by closure of openings.
Further, in described step (4), when Magnet being installed at skeleton, first with osteotome, bone marrow is taken out, be then placed in closing The Magnet of suitable size, Magnet will be less than bone surface 2mm;And with the gluing Magnet of glass and skeleton, then the bone marrow dug out is bonded to Position originally.
Further, in described step (4), according to the weight and volume in each portion splitting, magnetic material, fractionation portion are selected Weight is big and/or volume is big, selects the larger magnetic material of magnetic, fractionation portion weight is little and/or small volume then selects magnetic relatively Little magnetic material.
Further, the method can be used for making can assembly plastifying of Fish, reptiles, birds, mammal and the mankind Specimen.
Compared with prior art, the present invention has a following innovative point:
(1) present invention provide can assembled biological plasticized specimen manufacture method, with real organism as specimen, specimen is substantially Shape no changes, strong sense of reality, is conducive to later stage specimen to observe, and using simple to operate.
(2) present invention provide can assembled biological plasticized specimen manufacture method, can dismount, combine, can be according to school Teaching material part make or successively secondary explanation or learn, facilitate teacher teaching and Students ' Learning, also can for clinician's operative approach, The formulation of operation plan provides reference, specimen can realize the function of other more than one piece specimen.
(3) present invention provide can assembled biological plasticized specimen manufacture method, nonpoisonous and tasteless, be easy to preserve, when can be long Between be placed in the air, for user provide health-oriented products.
(4) present invention provide can assembled biological plasticized specimen manufacture method, the method can be many for a long time as specimen Secondary use, is that school saves instruction cost.
(5) present invention provide can assembled biological plasticized specimen manufacture method, with magnetic material as connector, no bright Aobvious external connection article, do not affect specimen structure and outward appearance.
Brief description
Magnet figure, in figure, 1. magnetic material are installed at Fig. 1 muscle;
Magnet figure is installed at Fig. 2 skeleton.
Specific embodiment
With reference to the accompanying drawing of the specific embodiment of the invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Whole description.
Embodiment 1
A kind of can assembled biological plasticized specimen manufacture method, comprise the following steps:
Step (1): selection, anti-corrosion, from fur is complete, no corrupt, atraumatic biological sample, with the formalin of 5-10% Biological sample is irrigated, makes formalin penetrate into each position of biological sample, the red blue dye of action venous perfusion of going forward side by side Material;
Step (2): dissect
The good specimen of preservative treatment is cut skin according to anatomical requirements and peels off, and save backup;
Find out subcutaneous shallow-layer arteriovenous and nerve, lymph in subcutaneous fat, do not dissociated and be retained in together with fat, so in end Afterwards in the distribution intersection of each structure, cut at fat and deep fascia, then peel off subcutaneous fat along this level, save backup;
Separate between each muscle and find out the nervus vasculairs of deep layer, remove fat therebetween and fascia, if deeper inconvenience behaviour Work can open the muscle interrupting its shallow-layer, but must save backup;
Along clavicle midpoint, anterior axillary line, side to umbilicuss level, level crosscutting to umbilicuss, 3 centimeters on another side to crista iliaca, along groin On ligament, 3 centimeters open abdominal cavity antetheca, and the needs of animal open the chest and abdomen of side along veutro median line, ilium intercostal lateral border Wall, saves backup;
Each internal organs are removed and dissects process, save backup, and solution cuts each structure of chest and abdomen rear wall;
On head 2 centimetres of ears along along geisoma, horizontal line opens scalp, braincap, display dura mater and brain, saves backup;
Face removes side superficial muscular, side mandibular bone, saves backup;
Step (3): dewatering and defatting and vacuum impregnation
Dewatering and defatting and vacuum impregnation are carried out to the biological sample in step (2);
Described dewatering and defatting: replace the in-house moisture of specimen and fat with acetone;
Described vacuum impregnation: replace the in-house acetone of specimen with fluid silicone rubber;
Step (4): install magnetic material
The specimen that dipping is completed is taken out from fluid silicone rubber;
Tear departmentalism organ as needed open;
According to the weight and volume in each portion splitting, select magnetic material;
According to the position relationship between each portion, on the premise of the correctness ensureing organ structure and integrity, magnetic material The deep layer being respectively installed to each portion organ contact surface (according to the weight and volume in each portion splitting, selects magnetic material, fractionation portion Weight is big and/or volume is big, selects the larger magnetic material of magnetic, fractionation portion weight is little and/or small volume then selects magnetic relatively Little magnetic material, in the deep layer of each portion organ contact surface, its depth is optimal with 1-2cm, so that biological sample reaches for magnetic material Firmly be advisable to stable), according to " the mutual repulsion of magnetic pole of the same name, synonyms pole is attracted each other " principle each portion organ contact surface Deep layer install magnetic material (generally, magnetic material refers to Magnet, for example: a and b is two of organ and contacts with each other Anatomic components, in the contact surface depths of a part, n pole Magnet is installed, in the contact surface depths of b part, s pole Magnet is installed, works as a After the contact surface depths of part installs a number of n pole Magnet, when s pole Magnet is installed in the contact surface depths of b part, Meet under other conditions, allow as far as possible s pole Magnet from n pole Magnet more close to better) captivation that makes adjacent each portion organ is maximum;
When Magnet being installed at muscle, first raised one layer of 2 millimeters thick, be slightly wider than the flesh of magnet diameter along myofilament direction with scalpel Silk, forms opening, Magnet is put in opening, the myofilament then raised with glass cement bonding, by closure of openings.Installation results are such as Shown in Fig. 1.
When filling Magnet at skeleton, first with osteotome, bone marrow is taken out, be then placed in the Magnet of suitable size, Magnet will be less than bone 2 millimeters of surface.With the gluing Magnet of glass and skeleton, then the bone marrow taking out is bonded to original position.Installation results such as Fig. 2 institute Show.
Step (5): combination
Each portion organ of magnetic material will be installed in step (4), combine from deep to shallow with form according to the original position of organism Together, separated with plastic sheeting between each branch;
Step (6): solidification
Biological sample after step (5) is combined is solidified with silicone rubber firming agent;
Step (7): finishing
The biological glue of the biological sample excess surface after step (6) is solidified and the exposed plastic sheeting in each several part extraorgan Remove, that is, complete the making of specimen.
Above embodiment is only that the preferred embodiment of the present invention is described, and not the scope of the present invention is entered Row limits, and on the premise of without departing from design spirit of the present invention, those skilled in the art make to technical scheme Various modifications and improvement, each fall within the protection domain of claims of the present invention determination.

Claims (6)

1. a kind of can assembled biological plasticized specimen manufacture method it is characterised in that comprising the following steps:
Step (1): selection, preservative treatment, from fur is complete, no corrupt, atraumatic biological sample, with the Fu Er of 5-10% Malin is irrigated to biological sample, makes formalin penetrate into each position of biological sample, and action venous perfusion of going forward side by side is red Blue dyestuff;
Step (2): dissect
The specimen that step (1) is handled well is cut skin according to anatomical requirements and is peeled off, and saves backup;
Step (3): dewatering and defatting and vacuum impregnation
Biological sample in step (2) is carried out dewatering and defatting and vacuum impregnation;Described dewatering and defatting: replace specimen with acetone In-house moisture and fat;Described vacuum impregnation: replace the in-house acetone of specimen with fluid silicone rubber;
Step (4): install magnetic material
The specimen that dipping is completed is taken out from silicone rubber;
Tear departmentalism organ as needed open;
According to the weight and volume of each portion organ splitting, select magnetic material;
According to the position relationship between each portion, on the premise of the correctness ensureing organ structure and integrity, magnetic material It is respectively installed to the deep layer of each portion organ contact surface, existed according to " the mutual repulsion of magnetic pole of the same name, synonyms pole is attracted each other " principle The deep layer of the contact surface of each portion organ installs magnetic material;
Step (5): combination
Each portion organ of magnetic material will be installed in step (4), combine from deep to shallow with form according to the original position of organism Together, separated with plastic sheeting between each portion organ of fractionation;
Step (6): solidification
Biological sample after step (5) is combined is solidified with silicone rubber firming agent;
Step (7): finishing
The silicone rubber of the biological sample excess surface after step (6) is solidified and the exposed plastic sheeting in each portion extraorgan go Fall, that is, complete the making of specimen.
2. according to claim 1 can assembled biological plasticized specimen manufacture method it is characterised in that described step (4), in, described magnetic material is Magnet.
3. according to claim 1 can assembled biological plasticized specimen manufacture method it is characterised in that described step (4), in, when magnetic material being installed at muscle, first raise myofilament with scalpel along myofilament direction, form opening, magnetic material is put In opening, then use glass cement bonding myofilament, by closure of openings.
4. according to claim 1 can assembled biological plasticized specimen manufacture method it is characterised in that described step (4), in, when Magnet being installed at skeleton, first with osteotome, bone marrow is taken out, be then placed in the magnetic material of suitable size, magnetic material To be less than bone surface 2mm;And with glass cement adhering magnetic material and skeleton, then the bone marrow dug out is bonded to original position.
5. according to claim 1 can assembled biological plasticized specimen manufacture method it is characterised in that described step (4) in, according to the weight and volume of each portion organ splitting, select magnetic material, fractionation portion weight is big and/or volume is big, choosing Select the larger magnetic material of magnetic, fractionation portion weight is little and/or small volume then selects the less magnetic material of magnetic.
6. according to claim 1-5 arbitrary described can assembled biological plasticized specimen manufacture method it is characterised in that the method Can be used for making Fish, reptiles, birds, mammal and the mankind assembled can plastify specimen.
CN201611079077.8A 2016-11-30 2016-11-30 It is a kind of can assembled biological plasticized sample production method Active CN106373475B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107767750A (en) * 2017-12-01 2018-03-06 河南中博生物塑化科技有限公司 A kind of operating theater instruments biological sample and preparation method thereof
CN107784908A (en) * 2017-12-01 2018-03-09 河南中博生物塑化科技有限公司 A kind of Chinese medicine acupuncture biological sample and preparation method thereof
CN108922355A (en) * 2018-07-13 2018-11-30 河南中博健康科技有限公司 Biological plasticized sample and preparation method thereof is combined in human body separation
CN109090096A (en) * 2018-09-28 2018-12-28 河南科技大学 A kind of production method of fish guts plasticizing sample
CN109526938A (en) * 2018-12-27 2019-03-29 湖南省锘恩科德生物科技有限公司 A kind of sample disposal liquid and the method using treatment fluid production zoological specimens
CN109744225A (en) * 2019-01-17 2019-05-14 河南中博科技有限公司 Animal skeleton is plasticized sample and preparation method thereof
CN111374792A (en) * 2020-02-21 2020-07-07 大连医科大学 Dissection method for displaying fish muscle interval anatomical features
CN111557299A (en) * 2020-04-15 2020-08-21 昆山周庄鸿峰生命奥秘博物馆有限公司 Specimen preparation method
CN111919833A (en) * 2020-08-13 2020-11-13 大连鸿峰生物科技有限公司 Whale dolphin tail fin specimen manufacturing method and device
CN113575570A (en) * 2021-09-01 2021-11-02 河南中博科技有限公司 Method for manufacturing plasticized specimen not easy to mildew

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CN203191234U (en) * 2013-01-16 2013-09-11 长沙康柏恩医疗科技有限公司 Fast-slow type double-purpose automatic biological tissue dehydrator of single-specimen processing cylinder
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CN101196443A (en) * 2006-12-04 2008-06-11 华东师范大学第二附属中学 Color fixing and plasticizing method for plant leaf blade specimen
US20090191535A1 (en) * 2007-12-22 2009-07-30 Mark Carle Connelly Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
CN102379280A (en) * 2011-08-05 2012-03-21 云南省烟草农业科学研究院 Tobacco leaf specimen treatment liquid and flue-cured tobacco leaf specimen batch production and preservation method
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107767750A (en) * 2017-12-01 2018-03-06 河南中博生物塑化科技有限公司 A kind of operating theater instruments biological sample and preparation method thereof
CN107784908A (en) * 2017-12-01 2018-03-09 河南中博生物塑化科技有限公司 A kind of Chinese medicine acupuncture biological sample and preparation method thereof
CN108922355A (en) * 2018-07-13 2018-11-30 河南中博健康科技有限公司 Biological plasticized sample and preparation method thereof is combined in human body separation
CN109090096A (en) * 2018-09-28 2018-12-28 河南科技大学 A kind of production method of fish guts plasticizing sample
CN109526938A (en) * 2018-12-27 2019-03-29 湖南省锘恩科德生物科技有限公司 A kind of sample disposal liquid and the method using treatment fluid production zoological specimens
CN109744225A (en) * 2019-01-17 2019-05-14 河南中博科技有限公司 Animal skeleton is plasticized sample and preparation method thereof
CN111374792A (en) * 2020-02-21 2020-07-07 大连医科大学 Dissection method for displaying fish muscle interval anatomical features
CN111557299A (en) * 2020-04-15 2020-08-21 昆山周庄鸿峰生命奥秘博物馆有限公司 Specimen preparation method
CN111919833A (en) * 2020-08-13 2020-11-13 大连鸿峰生物科技有限公司 Whale dolphin tail fin specimen manufacturing method and device
CN113575570A (en) * 2021-09-01 2021-11-02 河南中博科技有限公司 Method for manufacturing plasticized specimen not easy to mildew

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