CN1063617C - Food therapeutic products - Google Patents
Food therapeutic products Download PDFInfo
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- CN1063617C CN1063617C CN98119068A CN98119068A CN1063617C CN 1063617 C CN1063617 C CN 1063617C CN 98119068 A CN98119068 A CN 98119068A CN 98119068 A CN98119068 A CN 98119068A CN 1063617 C CN1063617 C CN 1063617C
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Abstract
The present invention relates to a dietary health-care product, the prescription of which comprises: barbary wolfberry fruit, vitamin E succinate, spirulina fine powder, litesse, carrot powder, calcium gluconate, whole wheat flour, corn flour, red bean, mung bean and stevioside. The finished product is prepared by proportionally selecting materials, drying, weighing, uniformly mixing, forming by puffing and separately loading. The novel health-care food has the health-care functions of inhibiting tumor, regulating blood fat, regulating blood sugar, regulating immunity and delaying aging, and the present invention can be widely used as a dietary health-care product for patients with cancer, cardiovascular disease, cerebrovascular disease and diabetes.
Description
The present invention relates to health food, be in particular patients' such as cardiovascular and cerebrovascular disease, tumor, diabetes a kind of food therapeutic health and method for making thereof.
The inhibition tumour medicine of cancer patient's use at present mostly is the chemosynthesis material, and toxic and side effects is big, except that anticancer, also kills and wounds normal cell, makes leukopenia as cyclophosphamide, and immunologic function reduces.Ametycin can bring out hereditary material damage etc., and cancer chemotherapy is very big to life damage.The cancer X-ray therapy is is also killed and wounded normal cell except that killing and wounding cancerous cell, makes leukopenia reduce immunologic function.And diabetics.The cardiovascular and cerebrovascular disease patient also can only carry out pharmacotherapy at present, and the scope of eaten food also is restricted, and this brings multiple inconvenience just for this class patient.
Task of the present invention is: overcomes the deficiencies in the prior art, proposes a kind ofly can suppress tumor cell, do not kill and wound normal cell again, and can the human body immunity improving function, slow down aging, the food therapeutic health that the people is had good health and a long life.
Task of the present invention realizes as follows:
The raw material of food therapeutic health is:
Fructus Lycii 20%, vitamin e succinate 0.1%, spirulina powder 1%, litesse 1%, Radix Dauci Sativae powder 1%, calcium gluconate 2%, whole wheat flour 50%, Semen Maydis powder 15%, Semen Ormosiae Hosiei powder 15%, Semen phaseoli radiati powder 1%, stevioside 0.5%.
Its production process is: takes by weighing various compositions at first according to the above ratio, carries out drying then, make it water content below 9%, and mix homogeneously, expanded molding, packing is finished product.
Because the effective ingredient of prescription of the present invention contains: lycium barbarum polysaccharide, vitamin e succinate.Organic selenium, organic germanium, organic chromium, organic calcium, dietary fiber, carotene, vitamin C-vitamin E, several amino acids (containing eight kinds of essential amino acids) therefore have the tumor of inhibition, blood sugar regulation, blood lipid regulation.The health care of immunomodulating, slow down aging.
Simultaneously, be solid, shaped because food of the present invention is prepared food, then dry-eating and blister all can, edible and carry all and make things convenient for.
The present invention has the scientific basis of five health cares:
1. inhibition tumor:
[1] this product can obviously suppress the S180 tumor heavily, and significantly improves the tumor-bearing mice spleens cell number.Obvious promotion spleen activating T cell propagation is recovered and enhancing tumor-bearing mice body cell immunologic function and TNFB secretion level and but the possibility mechanism of tumor effect thereof.All there are serious side effects such as suppressing body's immunity in the radiotherapy of tumor and chemotherapy.This product has goodish prospect in strengthening the anti-tumor activity immunochemotherapy.
[2] this product obviously suppresses the growth of rat sarcoma W256, its tumour inhibiting rate 95.6%.
[3] this product can prolong the life of ehrlich carcinoma mice, and rate elongation 52% compares with normal saline, and its difference has utmost point significance (P＜0.01)
[4] this product has the obvious suppression effect in the mutagenesis activity to N-2-Fluorenylamine (2-AF) TA100 bacterial strain, the SCE in human lymphocytes frequency that simultaneously ametycin (MMC) is brought out obviously reduces, prompting has antagonism to the genetic damage that some hereditary poisonous substance causes, but antagonism chemotherapy of tumors and radiotherapy side effect.
[5] this product all has obvious inhibitory action to people's adenocarcinoma of stomach KATO-3 cell and human cervical carcinoma Hala cell, and its mechanism of action shows that mainly suppressing cell DNA synthesizes, the interference cell division, and cell is grown ability drop again.To macrophage on, all has activation at non-specific antitumor or specificity antineoplastic.Acute hypoxic tumor cells is had certain radiosensitizing effect, and combination with radiotherapeutic then demonstrates tangible radiosensitizing effect.
[6] this product can make people's breast cancer cell and prostate gland cancer cell apoptosis, and people's normal cell is injury-free, and this is can intuitively see cancer cell death by advanced person's molecular biology experiment means under fluorescence microscope.The banded variation takes place in DNA.This is that this product can suppress the go-go science of tumor and proves.
2. immunomodulating
[1] this product has regulating action of the utmost importance to human immunity function, can obviously regulate T.B.CTL.
The isocellular function of NK.IL-2 and IL-3 are had dual regulation, and promote the expression of IL-2R, the generation of inducing IL-6 and TNF.In tumour immunity and neuroendocrine immunomodulating net, has immune enhancing function.
[2] this product suppresses the inductive mouse chest cell apoptosis of DEX, uses the PL method and detects inferior 2 times of somatic cells, and the diphenylamines method is measured thymocyte cell dna segment % and dna gel electrophoresis, and this product can suppress the inductive dna segmentization of DEX as a result.
[3] 117 healthy old mens (60-82 year) and 44 young and middle-aged normal persons are carried out several test on immune function, observe this product old Immune Effects.Wherein go into to take back E-Flos Rosae Rugosae 73 old age and form cell percentage (E-RFC%) the average bonded sheep red blood cell of each bow structure (SRBC) number, lymhocyte transformation rate (LBT), serum lysozyme content, all than obviously improving before the clothes, wherein LBT and LZM content reach young and middle-aged group of level to T cell absolute value.Illustrate that this product can increase the amount of T cell surface E receptor, and the quantity by increasing the T cell and strengthen that it is active and the immunity system is produced regulating action.
[4] this product not only can improve conventional LAK activity in vivo, and can improve quick LAK activity.
[5] TNF has the active a kind of cytokine of various biological, according to its cell source and gene structure, can be divided into two classes is that TNF α and TNF β are mainly secreted by mononuclear phagocyte, TNF β is mainly produced by activating T cell, and the TNF that induces whole blood to produce with LPS is mainly TNF α, and TNF has antitumor, infection, the activation polymorphonuclear leukocyte induces IL-1 synthetic, promotes effects such as PGE secretion and collagenase generation.The antitumor of this product, infection, effect such as immunomodulating may be relevant therewith.
[6] this product is in treatment rat Walker carcinosarcoma 256, and the cell minimizing that cyclophosphamide is caused has obvious protective effect.
3. blood sugar regulation
Irritate stomach with alloxan (Alloxan) 160mg/kg (5) dosage and make the rabbit diabetes animal model, irritating stomach with this product is experimental group, and normal saline is organized in contrast, continuous ten days.Respectively to taking a blood sample normal epoch, experiment periods, the tailend of experimental group, with enzymatic assays empty stomach, 0.5h, lh 1.5h and 2h serum level of glucose (carbohydrate tolerance) from ear vein; Put the method for exempting from and survey serum insulin levels, glucose tolerance curve obviously moves down as a result, and the blood sugar lowering effective percentage reaches 100%.
With the matched group Diabetic Rabbits of normal saline filling stomach, blood glucose maintains high level always, and none reaches sequential experiment blood sugar lowering effect level.
Because alloxan is to the damage of beta Cell of islet, secretion of insulin does not raise with the rising of blood sugar level.
This product does not have influence to normal mouse blood sugar.
Above-mentioned experimental results show that: this product has the obvious functions of blood sugar effect.
This product is rich in organic chromium and high dietary-fiber and low fat, low in calories be the mechanism of blood sugar lowering.
4. blood lipid regulation
This product descends with T value to the elderly men hyperlipidemia is many: E
2Value, E
2/ T ratio raises.After this product treatment 3 months, obviously descend (p＜0.01) with TC, TG, LDT-C concentration in the deficiency of the kidney yin of Chinese medical discrimination typing, the liver yang-excess type blood, T value obviously rises E in the blood simultaneously
2Value, E
2/ T ratio decline (P＜0.01).
Therapeutic outcome shows: this product has preferably in the effect for reducing fat and rising blood T value and reduces the effect of E2 value.
5. slow down aging:
[1] this product can prolong the life-span of mice, fruit bat, silkworm, has antioxidation, can regulate body's immunity, to the senile symptom effect of having clear improvement.
[2] antioxidation: unsaturated fatty acid forms lipid peroxide (LPO) in the free radical that old people's cylinder accumulation is too much, it and biomembrane, and then causes cell rupture and carry out sexually transmitted disease (STD) and become.This product suppresses the generation of lipid peroxide significantly, has antioxidation, suppression ratio reach 87～98% before and after the oral this product of 25 old peoples of test the content of SOD, LPO in the blood, find obviously to raise before the active clothes of SOD in the clothes bleeding from anus, LPO obviously reduces before the clothes, each is organized notable difference between mean, prompting has the enhancing body anti-aging effects.
[3] the metabolic effect of pair cell: cellular metabolism is whole metabolic basis, and whole metabolic alterations will inevitably reflect to some extent on cellular level that with age, impaired DNA increases, and the DNA repair ability weakens.Utilize non-program DNA synthetic method to measure the DNA repair ability of the oral this product of 19 old peoples (60～80 years old) front and back periphery lymphocyte, the result shows, can obviously strengthen human DNA after oral this product and repair synthesis capability (P＜0.01), and the amplitude that discovery women DNA repair ability increases is greater than the male.
[4] improve senile symptom: this product give respectively 36 examples more than 60 years old the old people to take for 4 weeks be a course of treatment, through finding after two courses of treatment, the symptom relevant with aging has clear improvement effective percentage 82.50% as giddy, fatiguability, uncomfortable in chest, dyssomnia, inappetence, easy catching a cold etc.
[5] by health check-up to old people before and after 20 example clothes this product, the activity of T lymphocyte and lymphokine IL-2 thereof dynamic observes, after finding that they took for three weeks, human T-cell's transformation function more than 2/3 on average increases by 3.28 times (1～7 times), 2.26 times (0.5～5.0 times) of active average increase of IL-2, clinically generally show as in high spiritsly, appetite is good, and sleep is good etc.Obey not only slow down aging process for a long time, and can strengthen infection,, antitumor and immune surveillance function.
[6] this product has the nucleus formation of obvious inhibition mouse liver even slurry lipid peroxide (LPO), and becomes dose-response relationship.Experiment confirm can obviously suppress the LPO generation in the mice body, and (GSH-PX) vigor of glutathion peroxidase in the blood and erythrocyte are increased towards oxide dismutase (SOD) vigor; Human experimentation shows that can obviously suppress Serum LPO generates, and increases the GSH-PX activity in the blood.Proof this product has anti-aging effects.
[7] this product is rich in selenium Se, copper Cu, zinc Zn, manganese Mn.
Se is one of composition of GSH-PX, and Se can lead to GSH-PX and stop the free-radical generating lipid peroxidation, thereby the protection cell membrane exempts from infringement.Zn also participates in the synthetic of various enzymes except that participation SOD is synthetic, wherein archaeal dna polymerase, RNA polymerase directly influence nucleic acid and protein synthesis.Occur above-mentioned protein synthesis obstacle and histiocyte parasthenia during the human body zinc deficiency, quicken old people's aging.Mn also is the constituent of enzymes such as plurality of enzymes such as RNA polymerase, and the old people lacks Mn can influence thyroxinic synthetic and secretion, and the decline of thyroxine function also is one of aging factor.It is essential that Cu, Zn, Mn are the active institute of SOD.
The also germanic Ge of this product, organic germanium compounds can stimulate and generate interferon (INF) in the body, and the antitumaous effect of INF to be generation recognize altogether.Think that now germanium has different repairs to injured immune system, can activate NK and macrophage.In view of Zn, Cu, Se, Mn in China old people serum all are lower than the young and the middle aged, therefore, exogenous additional this product antagonism aging will be a valid approach.
Claims (2)
1. food therapeutic health, it is characterized in that: the raw material of health product is: Fructus Lycii 20%.Vitamin e succinate 0.1%.Litesse 1%.Radix Dauci Sativae powder 1%.Spirulina powder 1%.Calcium gluconate 2%.Whole wheat flour 50%.Semen Maydis powder 15%.Semen Ormosiae Hosiei powder 15%.Semen phaseoli radiati powder 1%.Stevioside 0.5% is made through expanded.
2. one kind requires the manufacture method of described health product it is characterized in that as right 1: a. gets material in proportion; B. dry, make it water content below 9%; C. mix homogeneously; D. expanded molding; E. packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98119068A CN1063617C (en) | 1998-10-13 | 1998-10-13 | Food therapeutic products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98119068A CN1063617C (en) | 1998-10-13 | 1998-10-13 | Food therapeutic products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1213510A CN1213510A (en) | 1999-04-14 |
| CN1063617C true CN1063617C (en) | 2001-03-28 |
Family
ID=5226257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98119068A Expired - Fee Related CN1063617C (en) | 1998-10-13 | 1998-10-13 | Food therapeutic products |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1063617C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032324B (en) * | 2007-03-30 | 2011-03-23 | 董强功 | Total nutrient foods and preparing method |
| CN104873547B (en) * | 2015-05-31 | 2016-05-11 | 芦红代 | A kind of pharmaceutical composition and preparation and purposes |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1125520A (en) * | 1994-12-28 | 1996-07-03 | 邸凤阁 | Curative effect food "xiaokele" for diabete |
| CN1144050A (en) * | 1995-01-24 | 1997-03-05 | 北京恒明技术开发中心 | Food with function of reducing blood sugar |
-
1998
- 1998-10-13 CN CN98119068A patent/CN1063617C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1125520A (en) * | 1994-12-28 | 1996-07-03 | 邸凤阁 | Curative effect food "xiaokele" for diabete |
| CN1144050A (en) * | 1995-01-24 | 1997-03-05 | 北京恒明技术开发中心 | Food with function of reducing blood sugar |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1213510A (en) | 1999-04-14 |
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