CN110150654A - A kind of special medicine purposes formula food for tumor patient - Google Patents
A kind of special medicine purposes formula food for tumor patient Download PDFInfo
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- CN110150654A CN110150654A CN201910542616.4A CN201910542616A CN110150654A CN 110150654 A CN110150654 A CN 110150654A CN 201910542616 A CN201910542616 A CN 201910542616A CN 110150654 A CN110150654 A CN 110150654A
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- powder
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- formula food
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Abstract
The invention discloses a kind of special medicine purposes formula foods for tumor patient, comprising: 20-40 parts of protein, fatty 10~15 parts, 25~55 parts of carbohydrate, 4~10 parts of dietary fiber, 2~10 parts of diet essence, 0.01-2 parts of mineral complex;0.01-1 parts of vitamin complex;1~5 part of integration of drinking and medicinal herbs ingredient;Wherein, fat is at least one of omega-3 polyunsaturated fatty acids, including alpha-linolenic acid, eicosapentaenoic acid, clupanodonic acid, docosahexaenoic acid;Wherein, diet essence includes at least one of mushroom powder, Kelp Powder, konjaku flour, walnut powder, black tea powder, apple powder, corn flour, chicken meal, broccoli powder.The food is for maintaining, ensureing that neoplastic disease states crowd physiological function, physical rehabilitation play a significant role, its weight loss that can significantly improve tumor patient simultaneously reduces complication, increase tumor patient nutrition intake and quality of making the life better, whole-course treatment as the 4th therapy laid equal stress on operation, radiotherapy, chemotherapy, for tumor patient.
Description
Technical field
The present invention relates to a kind of food formula more particularly to a kind of special medicine purposes formula foods for tumor patient
Product.
Background technique
Tumor patient is malnutritive, does not only result in patient and treats under tolerance decline, therapeutic effect decline, quality of life
Drop, decreased survival time, complication increase, and bring huge financial burden to patient home.
Tumor disease often results in patient's organism metabolic disorder, physical deterioration, and can cause different degrees of malnutrition.
It is also a kind of wound to body although surgical operation is a kind of remedy measures for tumour.Stimulation and wound due to operation
The needs of tissue repair, catabolism enhancing, the increase in demand to nutriments such as protein of body.Meanwhile postoperative patient
Resistance decline, postoperative patient usually have fever, infection, metabolic disorder, appetite stimulator, digestion and absorption function decline etc. diseases
Shape, or even severe complication occurs.Daily diet is limited, affects the healing of wound and the recovery of constitution.
5 years survival rates of China's tumor patient not as good as the U.S. half, the reason is that various, wherein ignore medicine
The alimentotheray of purposes formula food is a major reason.
Special medicine purposes formula food is to meet limited feed, Disorder of Digestion and A orption, metabolic disorder or specific disease
The formula food being formulated specially is processed in special requirement of the diseased state crowd to nutrient or diet.Such product must be
It is individually edible or matched with other food under the guidance of doctor or clinical nutrition teacher.Special medicine purposes formula food is only
It is only that one of the approach of nutritional support is provided for clinical patient, provides a kind of selection mode for clinical nutritional support.
And current nutritional formulas majority is only applicable to certain types of tumor patient, for other kinds of tumour
The less effective of patient;And its composition is relatively partial to western diet habit, it is antitumor for having for Chinese population eating habit
The full nutrition formula food of effect is then fewer.
Summary of the invention
The purpose of the present invention is to overcome the defects in the prior art, provides a kind of special medicine use for tumor patient
Way formula food, is based on the distinctive eating habit of Chinese and raw material, and the nutrition of the supplement tumor patient of general equilibrium needs
It asks, and further improves the physical fitness and resistance of tumor patient, the side effect during remissive treatment simultaneously promotes tumour
Prognosis.
To achieve the above object, the present invention adopts the following technical scheme:
The present invention provides a kind of special medicine purposes formula food for tumor patient comprising following component and its again
Measure number: 20-40 parts of protein, fatty 10~15 parts, 25~55 parts of carbohydrate, 4~10 parts of dietary fiber, diet essence
2~10 parts, 0.01-2 parts of mineral complex;0.01-1 parts of vitamin complex;1~5 part of integration of drinking and medicinal herbs ingredient;
Wherein, the fat is omega-3 polyunsaturated fatty acids, including alpha-linolenic acid, eicosapentaenoic acid, 22 carbon
At least one of five olefin(e) acid, docosahexaenoic acid;
Wherein, the diet essence includes mushroom powder, Kelp Powder, konjaku flour, walnut powder, black tea powder, apple powder, corn
At least one of powder, chicken meal, broccoli powder.
In order to advanced optimize the above-mentioned special medicine purposes formula food for tumor patient, the technology that the present invention takes
Measure further include:
Further, the protein includes lactalbumin, fish scale collagen, whole milk powder, soyabean protein powder, soybean
At least one of Gly-His-Lys, nucleotide, arginine, leucine.
Further, the dietary fiber include oligofructose, xylo-oligosaccharide, pectin, beta glucan, in inulin at least
It is a kind of.
Further, the carbohydrate includes at least one of maltodextrin, glucose, sucrose, starch.
Further, the vitamin complex includes vitamin A, vitamin D, vitamin E, vitamin K1, vitamin
B1, vitamin B2, vitamin B6, vitamin B12, niacin, folic acid, pantothenic acid, vitamin C, biotin;
Further, the mineral complex includes sodium, potassium, copper, magnesium, iron, zinc, manganese, calcium, phosphorus, iodine, selenium.
Further, the integration of drinking and medicinal herbs ingredient includes purslane, cordate houttuynia, semen coicis, Poria cocos, ginseng, jujube.
Further, the formula food further includes 1-5 parts of polyoses extract, and the polyoses extract includes Dendrobidium huoshanness
At least one of polysaccharide, hedysarum polybotys saccharide, thizoma curculiginis polysaccharide, dictyophora fungus polysaccharide.
Further, the dosage form of the special medicine purposes formula food for tumor patient include: pulvis, powder,
Granule, capsule, tablet, emulsion or suspension.Its conventional method preparation for being all made of this field.
Above-mentioned formula food increases a certain amount of selenium, immunity of organism can be made to be improved, selenium and vitamin E can be to reinforcements
Synergistic effect has been immunized;
Addition has treatment tumour and improves the integration of drinking and medicinal herbs ingredient of immunocompetence in above-mentioned formula food, in which: dent
Amaranth has the function of clearing heat and detoxicating, cooling blood and hemostasis, and active constituent can selectively kill cancer cell, have increasing to chemotherapeutics
Effect attenuation, cancer cell specific induction of apoptosis, while there is the Anticancers such as the effect of class biological response modifiers, Antineoplastic angiogenesis work
With;There is cordate houttuynia clearing heat and detoxicating, detumescence to treat sore effect, can play antitumor action by inducing apoptosis of tumour cell,
There is certain inhibiting effect to colon adenocarcinoma cell;Semen coicis has interference tumour cell cycle, inducing apoptosis of tumour cell, suppression
The proliferation of tumour cell processed, the expression for adjusting nuclear factor kappa B and cytokine interleukin -2 play it is antitumor and
Immunoregulation effect;Poria cocos has the effect of clearing damp and promoting diuresis, invigorating the spleen calming heart, and pachymaran ingredient therein has antitumor work
Property, enhance body's immunity, adjust cytokine secretion, energy reverse multiple drug resistance of tumor has the function that cancer-resisting;
Ginsenoside Rg1 contained in ginseng has immunologic enhancement, promotes lymphopoiesis, improves NK cell, T lymphocyte
The activity of subgroup, inhibits tumour so as to improve patient immune function;Jujube has tonifying middle-Jiao and Qi, nourishing blood and tranquilization, mitigates pharmacological property
Function, can improve the immunity of the human body, and can inhibit cancer cell and other effects.
Addition has the diet essence of certain dietotherapy characteristic in above-mentioned formula food, wherein mushroom powder energy stomach invigorating QI invigorating is helped
Positive qi-restoratives, wind-dispelling promoting eruption, wherein the lentinan contained can enhance cellular immunity and humoral immunity, to inhibit the life of cancer cell
It is long;Broccoli powder not only can supplement a certain amount of selenium and vitamin C to people, while can also supply carrotene abundant, play
The effect for preventing intraepithelial neoplasia cells from being formed, inhibits cancerous swelling growth, and ascorbic acid also rich in can enhance the solution of liver
Malicious ability improves body power;Black tea being capable of warm stomach, moreover it is possible to which anti-inflammatory, protection stomach lining also have certain effect to treatment ulcer.
It also added suitable polyoses extract in above-mentioned formula food, be remarkably improved the immune of tumor patient
Power, and there is significant antitumor efficacy.
The omega-3 polyunsaturated fatty acids added in above-mentioned formula food all have inhibiting effect to various tumours, can increase
Strong immunity of organisms inhibits cancer cell and endothelial cell to adhere to, and volume can inhibit the expression and function of oncogene coding albumen.
Compared with prior art, the present invention has the advantages that by adopting the above technical scheme
This special medicine purposes formula food meets limited feed, Disorder of Digestion and A orption, metabolic disorder or specified disease
Special requirement of the state crowd to nutrient or diet, one kind formula food made of special processing configuration.
The food is for maintaining, ensureing that neoplastic disease states crowd physiological function, physical rehabilitation play a significant role, energy
It enough significantly improves the weight loss of tumor patient and reduces complication, increase tumor patient nutrition intake and quality of making the life better,
Whole-course treatment as the 4th therapy laid equal stress on operation, radiotherapy, chemotherapy, for tumor patient.
Specific embodiment
With reference to embodiment, the specific embodiment of the present invention is further described.Following embodiment is only used for more
Add and clearly demonstrate technical solution of the present invention, and not intended to limit the protection scope of the present invention.
Embodiment 1
The present embodiment is the special medicine purposes formula food for tumor patient of a preferred versions comprising with the following group
Point:
Lactalbumin 10g, soyabean protein powder 10g, soy peptide powder 5g, arginine 0.5g;
Alpha-linolenic acid 2g, eicosapentaenoic acid 2g, clupanodonic acid 2g, docosahexaenoic acid 6g;
Maltodextrin 35g, starch 5g;
Oligofructose 5g, inulin 2g;
Mushroom powder 1.5g, Kelp Powder 1g, corn flour 2g, chicken meal 2g, broccoli powder 2g;
Sodium 440mg, potassium 590mg, 245 μ g of copper, magnesium 105mg, iron 4.5mg, zinc 4.5mg, 225 μ g of manganese, calcium 295mg, phosphorus
210mg, 35 μ g of iodine, 25 μ g of selenium;
200 μ g of vitamin A, 4 μ g of vitamin D, vitamin E 4mg, vitamin K125 μ g, vitamin B10.7mg, dimension
Raw element B20.7mg, vitamin B60.7mg, vitamin B120.7 μ g, niacin 4mg, folic acid 0.2mg, pantothenic acid 1.5mg, vitamin
C 80mg, 12 μ g of biotin;
Purslane 0.8g, cordate houttuynia 0.5g, semen coicis 0.5g, Poria cocos 0.8g, ginseng 1g, jujube 1g;
Dendrobidium huoshanness polysaccharide 0.5g, hedysarum polybotys saccharide 0.5g.
Preparation method are as follows: each component is ground into pulvis, crosses 100~200 meshes, by weight by sequences more less into
Row mixing, is made pulvis.
Embodiment 2
The present embodiment is the special medicine purposes formula food for tumor patient of a preferred versions comprising with the following group
Point:
Lactalbumin 10g, fish scale collagen 5g, whole milk powder 8g, soyabean protein powder 10g, arginine 0.5g, leucine
0.5g;
Alpha-linolenic acid 3g, docosahexaenoic acid 9g;
Maltodextrin 38g, glucose 3g, starch 7g;
Oligofructose 5g, pectin 1g, beta glucan 1g;
Mushroom powder 2g, Kelp Powder 1g, corn flour 2g, chicken meal 1g, black tea powder 1g, broccoli powder 1g;
Sodium 450mg, potassium 585mg, 225 μ g of copper, magnesium 98mg, iron 4.9mg, zinc 4.8mg, 240 μ g of manganese, calcium 315mg, phosphorus
205mg, 39 μ g of iodine, 27.5 μ g of selenium;
220 μ g of vitamin A, 4.8 μ g of vitamin D, vitamin E 4.5mg, vitamin K122 μ g, vitamin B1
0.75mg, vitamin B20.75mg, vitamin B60.75mg, vitamin B120.75 μ g, niacin 3.8mg, folic acid 0.21mg,
Pantothenic acid 1.7mg, vitamin C 82mg, 12.5 μ g of biotin;
Purslane 0.2g, cordate houttuynia 0.2g, semen coicis 0.2g, Poria cocos 0.2g, ginseng 0.5g, jujube 0.5g;
Dictyophora fungus polysaccharide 1.2g.
Preparation method are as follows: each component is ground into pulvis, crosses 100~200 meshes, by weight by sequences more less into
Mixed powder and auxiliary material homogeneous are prepared into direct-edible oral liquid by row mixing.
Embodiment 3
The present embodiment is the special medicine purposes formula food for tumor patient of a preferred versions comprising with the following group
Point:
20-40 parts of protein, 10~15 parts of fat, 25~55 parts of carbohydrate, 4~10 parts of dietary fiber, diet essence
2~10 parts, 0.01-2 parts of mineral complex of China;0.01-1 parts of vitamin complex;1~5 part of integration of drinking and medicinal herbs ingredient
Fish scale collagen 5g, whole milk powder 15g, soy peptide powder 15g, nucleotide 0.2g, arginine 0.4g, leucine
0.4g;
Docosahexaenoic acid 10g;
Maltodextrin 27g, starch 13g;
Oligofructose 6g, xylo-oligosaccharide 3g;
Mushroom powder 0.5g, Kelp Powder 0.5g, konjaku flour 0.5g, walnut powder 0.5g, black tea powder 0.5g, apple powder 0.5g, jade
Rice flour 0.5g, chicken meal 0.5g, broccoli powder 0.5g;
Sodium 435mg, potassium 602mg, 243 μ g of copper, magnesium 105mg, iron 4.3mg, zinc 4.3mg, 230 μ g of manganese, calcium 300mg, phosphorus
210mg, 36 μ g of iodine, 23 μ g of selenium;
205 μ g of vitamin A, 3.9 μ g of vitamin D, vitamin E 4.2mg, vitamin K124 μ g, vitamin B1
0.68mg, vitamin B20.68mg, vitamin B60.68mg, vitamin B120.68 μ g, niacin 4mg, folic acid 0.2mg, pantothenic acid
1.5mg, vitamin C 80mg, 11 μ g of biotin;
Purslane 0.32g, cordate houttuynia 0.32g, semen coicis 0.25g, Poria cocos 0.25g, ginseng 1g, jujube 1g;
Hedysarum polybotys saccharide 1g, thizoma curculiginis polysaccharide 1g, dictyophora fungus polysaccharide 1g.
Preparation method are as follows: each component is ground into pulvis, crosses 100~200 meshes, by weight by sequences more less into
Mixed powder, is pressed into direct-edible tablet by row mixing.
Application Example
Routinely dosage carries out the inhibiting effect to mouse transplanted sarcoma to the formula food prepared using Examples 1 to 3
Test, test procedure include:
Inoculation passage mouse S180 is taken, physiological saline is added in homogenizer, mouse S180 tumor homogenate is made, then with life
It manages salt water 1: 3 to dilute, then with 0.2ml/, only the left oxter of such as mouse is subcutaneous, is randomly divided into vaccinated mouse after 24 hours
Control group, example 1 group, 2 groups of embodiment, 3 groups of embodiment, every group 20.The daily gastric infusion of administration group mouse 1 time, every time
0.2mL/20g, control group give same amount of normal saline, and totally 7 days.It weighs before medication, next day of being discontinued puts to death mouse, weighs simultaneously
Subcutaneous tumor mass is removed in carefulness, records changes of weight and tumour inhibiting rate.The result is as follows:
Experimental group | Weight (g) before being administered | Weight (g) after drug withdrawal | Tumor weight (g) | Tumour inhibiting rate (%) |
Control group | 19.2 | 19.7 | 1.05 | - |
Example 1 group | 21.5 | 22.3 | 0.75 | 28.6 |
2 groups of embodiment | 20.7 | 21.9 | 0.68 | 35.2 |
3 groups of embodiment | 19.8 | 21.2 | 0.72 | 31.4 |
Note: tumour inhibiting rate=(control group knurl weight average value-administration group knurl weight average value)/control group knurl weight average value × 100.
From the foregoing, it will be observed that the formula food that 1~embodiment of the embodiment of the present invention 3 is configured, will not influence the normal of mouse
Growth, while it has apparent inhibiting effect to the knurl growth of mouse transplanted sarcoma S180.
Specific embodiments of the present invention are described in detail above, but it is only used as example, the present invention is not intended to limit
In particular embodiments described above.To those skilled in the art, the equivalent modifications and replace that any couple of present invention carries out
In generation, is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and repair
Change, all should be contained within the scope of the invention.
Claims (9)
1. a kind of special medicine purposes formula food for tumor patient, which is characterized in that including following component and its weight
Number: 20-40 parts of protein, fatty 10~15 parts, 25~55 parts of carbohydrate, 4~10 parts of dietary fiber, diet essence 2
~10 parts, 0.01-2 parts of mineral complex;0.01-1 parts of vitamin complex;1~5 part of integration of drinking and medicinal herbs ingredient;
Wherein, the fat is omega-3 polyunsaturated fatty acids, including alpha-linolenic acid, eicosapentaenoic acid, docosapentaenoic
At least one of acid, docosahexaenoic acid;
Wherein, the diet essence includes mushroom powder, Kelp Powder, konjaku flour, walnut powder, black tea powder, apple powder, corn flour, chicken
At least one of digested tankage, broccoli powder.
2. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that institute
State protein include lactalbumin, fish scale collagen, whole milk powder, soyabean protein powder, soy peptide powder, nucleotide, arginine,
At least one of leucine.
3. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that institute
Stating dietary fiber includes at least one of oligofructose, xylo-oligosaccharide, pectin, beta glucan, inulin.
4. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that institute
Stating carbohydrate includes at least one of maltodextrin, glucose, sucrose, starch.
5. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that the dimension
Raw element compound includes vitamin A, vitamin D, vitamin E, vitamin K1, vitamin B1, vitamin B2, vitamin B6, dimension life
Plain B12, niacin, folic acid, pantothenic acid, vitamin C, biotin.
6. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that the mine
Substance complex includes sodium, potassium, copper, magnesium, iron, zinc, manganese, calcium, phosphorus, iodine, selenium.
7. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that the medicine
Food includes purslane, cordate houttuynia, semen coicis, Poria cocos, ginseng, jujube with derived components.
8. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that described to match
Square food further includes 1-5 parts of polyoses extract;The polyoses extract include Dendrobidium huoshanness polysaccharide, hedysarum polybotys saccharide, thizoma curculiginis polysaccharide,
At least one of dictyophora fungus polysaccharide.
9. a kind of special medicine purposes formula food for tumor patient according to claim 1, which is characterized in that described to match
The dosage form of square food includes: pulvis, powder, granule, capsule, tablet, emulsion or suspension.
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CN111000224A (en) * | 2019-12-24 | 2020-04-14 | 中国海洋大学 | Formula food for improving survival rate of lung cancer cachexia patients |
CN111685262A (en) * | 2020-06-22 | 2020-09-22 | 广东燕岭特医食品有限公司 | Nutritional formula food for people in radiotherapy and chemotherapy and preparation method thereof |
CN111938145A (en) * | 2020-07-20 | 2020-11-17 | 江苏省肿瘤医院 | Nutritional formula for patients with esophageal cancer |
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CN107279978A (en) * | 2017-06-27 | 2017-10-24 | 佛山市南海天美事食品有限公司 | A kind of special medicine purposes formula food suitable for tumour patient |
CN108095088A (en) * | 2017-12-27 | 2018-06-01 | 福格森(武汉)生物科技股份有限公司 | Full nutrient formulation powder suitable for tumor patient rehabilitation and preparation method thereof |
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CN107279978A (en) * | 2017-06-27 | 2017-10-24 | 佛山市南海天美事食品有限公司 | A kind of special medicine purposes formula food suitable for tumour patient |
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CN111938145A (en) * | 2020-07-20 | 2020-11-17 | 江苏省肿瘤医院 | Nutritional formula for patients with esophageal cancer |
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