CN106361643A - Eupatorium adenophora spreng. skin-whitening mask - Google Patents
Eupatorium adenophora spreng. skin-whitening mask Download PDFInfo
- Publication number
- CN106361643A CN106361643A CN201610955922.7A CN201610955922A CN106361643A CN 106361643 A CN106361643 A CN 106361643A CN 201610955922 A CN201610955922 A CN 201610955922A CN 106361643 A CN106361643 A CN 106361643A
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- CN
- China
- Prior art keywords
- extract
- neohesperidin dihydrochalcone
- skin
- spreng
- adenophora
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a eupatorium adenophora spreng. skin-whitening mask, prepared from the following effective components: neohesperidin dihydrochalcone, a eupatorium adenophora spreng. extract and matrix, wherein the weight ratio of the eupatorium adenophora spreng. extract to the neohesperidin dihydrochalcone is equal to (10: 1) to (20: 1), the matrix comprises vitamin E magnesium phosphate ester, polyglyceryl-3 diisostearate, glycolic acid, linseed oil and hyaluronic acid. The eupatorium adenophora spreng. extract is taken as a main raw material, and the neohesperidin dihydrochalcone and the matrix are added into the raw material, so that the mask is low in price; the eupatorium adenophora spreng. extract is mixed with a small amount of the neohesperidin dihydrochalcone, so that a synergy effect for whitening is achieved; more particularly, when the weight ratio of the eupatorium adenophora spreng. extract to the neohesperidin dihydrochalcone is equal to (8: 1) to (10: 1), the skin-whitening effect is greatly improved.
Description
Technical field
The present invention relates to a kind of pale persicaria cleawhite pack, belong to cosmetic skin care product field.
Background technology
Facial film is the important content in skin nursing, for all kinds of skin characteristics regular application facial film, can make oiliness skin
Skin defat, thick pore is restrained, and the skin of withered gauffer recovers gloss, and the inflammation of skin sore skin is inhibited.Facial film
Skin is made to seem salubrious, smooth and pure white delicacy after use, this is because when facial film is coated on skin, facial film is produced with skin
Raw affinity, being gradually dried with facial film, skin temperature rise, blood circulation is accelerated, skin-tightening and tension force is strengthened, skin divides
The sebum secreted and moisture reverse osmosis, in horny layer, make epidermis softness unfold, pore instinct is opened, and the effective ingredient in facial film penetrates into
Skin is absorbed, and facial film is tightly connected with skin simultaneously, when removing facial film, deep in aging cutin on skin, pore
Layer dirt, also by leukorrhagia simultaneously, makes skin pure and fresh clean.
The principle of facial film, it is simply that using covering in the of short duration time of face, being temporarily isolating air and the pollution in the external world, carries
High skin temperature, the pore expansion of skin, promote sweat gland secretion and metabolism, so that the oxygen content of skin is increased, be conducive to flesh
Skin excludes the metabolic product of epidermis cell and the oil substances of accumulation, and the moisture in facial film penetrates into the angle of skin epidermis
Matter layer, skin becomes soft, and light is flexible naturally for skin.
, to beautiful pursuit, cosmetics species is more and more various for raising with people's quality of the life and people.
Pale persicaria (scientific name: eupatorium adenophora spreng.): perennial herb or one-tenth suffruticose are planted
Thing.The sturdy prosperity of rhizome, uprightly, plant height 30-200 centimetre, branch opposite, tiltedly on, stem purple, by white or rust pubescence.
Leaf opposite, blade matter is thin, and avette, triangle or Pedicellus et Pericarpium Trapae shape are avette, outside of belly green, and back side color is shallow, and edge has sparse thick and do not advise
Sawtooth then, is then wavy shallow sawtooth or nearly full edge below inflorescence.Head inflorescence is little, and diameter, up to 6 millimeters, arranges at branch end
Become umbrella room or compound corymb, containing about 40-50 little Hua, tubular flower both sexes, white.Son reality achene, pitchy.Can produce per year for every plant
Achene 10,000 about, mat pappus is propagated with the wind.November at florescence-April in next year, fruiting period March-April.
It is distributed mainly on the ground such as China, the U.S., Australia, New Zealand.It is a kind of important quarantine harmful organisms, be
China suffers from the exemplary of foreign term.Originate in Mexico, each in the world as a kind of ornamental plant from 19th century
Introduce a fine variety after, because its reproductive capacity is strong, it has also become global invasive species.In 2003 by China national Environmental Protection Administration and China
It is at the first place, at present for pale persicaria extract in " first Invasive Alien Species list Chinese " that academy of science issues
Be have not been reported using the application particularly in terms of whitening.
Content of the invention
The problem existing for above-mentioned prior art, the present invention provides a kind of pale persicaria cleawhite pack, with low cost, beautiful
White effect is good.
To achieve these goals, the technical solution used in the present invention is: a kind of pale persicaria cleawhite pack, the having of facial film
Effect composition includes neohesperidin dihydrochalcone, pale persicaria extract and substrate.
According to weight ratio, the weight of described pale persicaria extract and neohesperidin dihydrochalcone is than in 8:1-10:
1.
Described substrate is dimension e phosphate ester magnesium, -3 pairs of isostearates of polyglycereol, glycolic acid, oleum lini and hyaluronic acid.
Pale persicaria extract is mixed with neohesperidin dihydrochalcone and sequentially adds dimension e phosphate ester magnesium, polyglycereol -3
Double isostearates, glycolic acid, oleum lini heated and stirred dissolving, be cooled to about 30-50 DEG C, add hyaluronic acid so as to
Dissolving, obtains oil phase, by heated aqueous to about 90 DEG C about, stirring adds oil phase homogenate, carries out emulsifying stirring, cools,
Cream is become to obtain final product.
The present invention, with pale persicaria extract as primary raw material, adds neohesperidin dihydrochalcone and some substrate,
It is cheap, and pale persicaria extract mixes to play for whitening with a small amount of neohesperidin dihydrochalcone works in coordination with well
, in 8:1-10:1, whitening effect is significantly for the weight ratio of effect, particularly pale persicaria extract and neohesperidin dihydrochalcone
Degree improves.
Specific embodiment
The invention will be further described below.
Neohesperidin dihydrochalcone c28h36o15 cas 20702-77-6 is purchased from aksci company.
Chemical formula is as follows:
.
Embodiment 1:
The processing technology of described pale persicaria extract is 1) by the pale persicaria after vacuum drying, pulverize in pulverizer
To pale persicaria powder, pale persicaria powder is placed in the extraction kettle of supercritical extraction, 2) supercritical co2 is used as molten
Agent, concentration is that 65% ethanol does entrainer；3) adjust extraction kettle and extracting pressure is controlled in 25～30mpa, temperature control exists
45 DEG C, in 9l/h, extraction time controls in 2h for co2 flow-control, obtains pale persicaria extract.
8 parts of pale persicaria extracts are mixed with 1 part of neohesperidin dihydrochalcone and sequentially adds 15 parts of dimension e phosphate ester
Magnesium, -3 pairs of isostearates of 28 parts of polyglycereol, 24 parts of glycolic acid, 30 parts of oleum lini heated and stirred dissolvings, are cooled to about 30-
50 DEG C, add 40 parts of hyaluronic acids so as to dissolving, obtain oil phase, by heated aqueous to about 90 DEG C about, stirring adds oil phase even
Slurry, carries out emulsifying stirring, cools, and becomes cream to obtain final product.
Embodiment 2
As embodiment 1 processing technology, difference is: 10 parts of pale persicaria extracts are looked into 1 part of neohesperidin dihydro
You mix ketone.
As embodiment 1 processing technology, difference is comparative example 1: 8 parts of pale persicaria extracts and 4 parts of neohesperidins
Dihydrochalcone mixes
Comparative example 2
As embodiment 1 processing technology, difference is: 8 parts of pale persicaria extracts are looked into 7 parts of neohesperidin dihydros
You mix ketone.
Comparative example 3
As embodiment 1 processing technology, difference is: contains only 8 parts of pale persicaria extracts, does not contain neohesperidin
Dihydrochalcone.
Embodiment 4
As embodiment 1 processing technology, difference is: 8 parts of Semen Ginkgo extrac and 1 part of neohesperidin dihydrochalcone
Mixing.
Detection method:
Middle melanin genesis test in suppression mouse melanin cell.
By b16 mouse melanin tumor cell with 1 × 105The density of individual/ml is connected to the culture dish of a diameter of 9cm, at 37 DEG C
5%co2Under conditions of cultivate 2 days, abandon supernatant, add the sample solution 18-22ml after filtration sterilization, be then incubated for 3 days, abandon
Supernatant, pbs washs, and every hole adds the trypsin solution peptic cell 3min of 0.5ml mass percent 0.2%, and every ware adds 2ml dimension
Hold liquid and terminate digestion. after piping and druming mixes, every kind of concentration is taken out 0.5ml and is made cell counting. remaining cell suspension with 2500r/min from
Heart 5min, abandons supernatant, adds naoh solution in precipitation, and heating makes melanin dissolve, and selects the enzyme linked immunological of 490nm wavelength
Absorbance is surveyed on detector.
B16 cell suppression ratio=(1- (medicine hole absorbance+medicine hole cell density)+(control wells absorbance+right
According to hole cell density)) × 100%.
Middle melanin genesis test in suppression mouse melanin cell, result is as follows,
A is pale persicaria extract, and b is neohesperidin dihydrochalcone,
Above-mentioned test result indicate that, (8-10:1) mutually by a certain percentage for pale persicaria extract and neohesperidin dihydrochalcone
Between fusion there is collaborative whitening effect, can effectively suppress melanin to generate, and effect is significant.And between other ratios then
Have no synergism, whitening effect is inconspicuous.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not subject to above-described embodiment
Limit, the change made under other any spirit without departing from the present invention and principle is modified alternative combinations and simplified,
All should be equivalent substitute mode, be included within protection scope of the present invention.
Claims (3)
1. a kind of pale persicaria cleawhite pack is it is characterised in that the effective ingredient of facial film includes neohesperidin dihydrochalcone, acid
Mould leaf knotweed extract and substrate.
2. a kind of pale persicaria cleawhite pack according to claim 1 is it is characterised in that according to weight ratio, described acid
The weight of mould leaf knotweed extract and neohesperidin dihydrochalcone is than in 8:1-10:1.
3. a kind of pale persicaria cleawhite pack according to claim 1 is it is characterised in that described substrate is dimension e phosphoric acid
Fat magnesium, -3 pairs of isostearates of polyglycereol, glycolic acid, oleum lini and hyaluronic acid,
Pale persicaria extract is mixed with neohesperidin dihydrochalcone to sequentially add dimension e phosphate ester magnesium, polyglycereol -3 pairs different
Stearate, glycolic acid, the dissolving of oleum lini heated and stirred, are cooled to about 30-50 DEG C, add hyaluronic acid so as to dissolve,
Obtain oil phase, by heated aqueous to about 90 DEG C about, stirring adds oil phase homogenate, carries out emulsifying stirring, cools, and one-tenth cream is
?.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610955922.7A CN106361643A (en) | 2016-11-03 | 2016-11-03 | Eupatorium adenophora spreng. skin-whitening mask |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610955922.7A CN106361643A (en) | 2016-11-03 | 2016-11-03 | Eupatorium adenophora spreng. skin-whitening mask |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106361643A true CN106361643A (en) | 2017-02-01 |
Family
ID=57892738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610955922.7A Withdrawn CN106361643A (en) | 2016-11-03 | 2016-11-03 | Eupatorium adenophora spreng. skin-whitening mask |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106361643A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107822988A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of Sargent gloryvine cleawhite pack |
| CN107822989A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of centella cleawhite pack |
| CN107929125A (en) * | 2017-12-04 | 2018-04-20 | 刘晓冰 | A kind of valerian cleawhite pack |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006056831A (en) * | 2004-08-20 | 2006-03-02 | Shiseido Co Ltd | Protein oxidation inhibitor |
| CN102625693A (en) * | 2009-08-26 | 2012-08-01 | 玫琳凯有限公司 | Topical skin care formulations comprising plant extracts |
-
2016
- 2016-11-03 CN CN201610955922.7A patent/CN106361643A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006056831A (en) * | 2004-08-20 | 2006-03-02 | Shiseido Co Ltd | Protein oxidation inhibitor |
| CN102625693A (en) * | 2009-08-26 | 2012-08-01 | 玫琳凯有限公司 | Topical skin care formulations comprising plant extracts |
Non-Patent Citations (1)
| Title |
|---|
| 钱彦霖: "《罗平风物》", 30 November 2012, 云南人民出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107822988A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of Sargent gloryvine cleawhite pack |
| CN107822989A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of centella cleawhite pack |
| CN107929125A (en) * | 2017-12-04 | 2018-04-20 | 刘晓冰 | A kind of valerian cleawhite pack |
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| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170201 |