CN106344426A - Retina containing new zealand spinach polypeptide - Google Patents

Retina containing new zealand spinach polypeptide Download PDF

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Publication number
CN106344426A
CN106344426A CN201610882773.6A CN201610882773A CN106344426A CN 106344426 A CN106344426 A CN 106344426A CN 201610882773 A CN201610882773 A CN 201610882773A CN 106344426 A CN106344426 A CN 106344426A
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CN
China
Prior art keywords
polypeptide
herba tetragoniae
enzyme
tetragoniae
preparation
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201610882773.6A
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Chinese (zh)
Inventor
不公告发明人
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Foshan Jucheng Biochemical Technology Research and Development Co Ltd
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Guangzhou Danqi Daily Chemical Co Ltd
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Priority to CN201610882773.6A priority Critical patent/CN106344426A/en
Publication of CN106344426A publication Critical patent/CN106344426A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0204Specific forms not provided for by any of groups A61K8/0208 - A61K8/14
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a retina containing new zealand spinach polypeptide. The retina is prepared from the following ingredients in percentage by weight: 0.4-1% of the new zealand spinach polypeptide, 6-9% of glycerol, 0.2-0.4% of carbomer, 0.05-0.09% of sodium polyacrylate/polyethylene glycol-5M, 0.25-0.5% of sodium hyaluronate, 0.25-0.3% of triethanolamine, 0.2-0.4% of butanediol/water/peony root extract, 0.002-0.005% of diazolidinyl urea/iodic propynol-butyl Kinavosyl, 0.003-0.004% of methylisothiazolinone/iodicpropynol-butyl Kinavosyl, and the balance of deionized water, wherein the new zealand spinach polypeptide is prepared by enzymolysis based on neutral proteinase, papain and barley endopeptidase. The retina prepared by use of the new zealand spinach polypeptide not only is good in moisture preservation effect, but also has the effects of resisting wrinkles, repairing tissue damage and alleviating edema symptoms, and can be used for promoting cell regeneration, tensioning canthus skin and relieving pouches.

Description

A kind of eye mask containing Herba tetragoniae polypeptide
Technical field
The present invention relates to Cosmetic Manufacture field, particularly to a kind of fish collagen moisture saver mask and preparation method thereof.
Background technology
Eye mask is used to apply the cosmetics and skincare product of eye, for alleviating, improving eye black eye, microgroove, eye pouch, edema, thin The different skin problem such as stricture of vagina.
The Chinese invention patent application of Application No. 201210520285.2 provides a kind of Rhizoma Solani tuber osi Flos Rosae Rugosae eye mask, this eye Its main component of film includes dehydrated potato powder 65%-80%, Flos Rosae Rugosae powder 15%-25%, film former 5%-10%, wherein film forming Agent be sodium carboxymethyl cellulose, PVP k30 or be the mixture of the two.This invention can decompose desalination black The black eye that element leads to, effectively alleviate because of sleep or the rest not enough edema producing or tired phenomenon, the commonly used eyes that can allow Surrounding skin more lubricates.
The Chinese invention patent application of Application No. 201310570747.6 provides a kind of silkworm silk eye mask, the group of this eye mask Point and its percentage by weight be: fibroin 2%-4%, Flos Matricariae chamomillae water extract 5%-8%, Trenaxmine 0.1%-0.3%, sweet Oily 2%-4%, hyaluronic acid 0.08%-0.12%, hydrolyzed wheat protein 0.5%-0.8%, galactomannan 2%-3%, Water surplus.The effective ingredient of this invention fast and effectively can penetrate into human body skin, thus reach quickly dispelling eyes edema, black eye Circle, eye pouch, effect of eye wrinkle-removing.Fibroin and hydrolyzed wheat protein all contain abundant amino acid needed by human body, have Skin-care effect well.
Plant polypeptide generally has multiple good skin-care effects, is usually used in the preparation of cosmetics, and Herba tetragoniae polypeptide has Multiple effects such as moisturizing, crease-resistant, reparation, and molecular weight is low, skin is easy to absorb, for having good skin protection work(in cosmetics Effect, but at present its concrete application be have not been reported.
Content of the invention
The technical problem to be solved is to provide a kind of eye mask containing Herba tetragoniae polypeptide, is obtained using Herba tetragoniae polypeptide Eye mask moistening effect is good, has water lock ability, can solve the problems, such as multiple eye part skins simultaneously, recovers skin nature vigor.
The invention provides a kind of eye mask containing Herba tetragoniae polypeptide, described eye mask is by the group packet of following weight percentage Become:
Herba tetragoniae polypeptide: 0.4%-1%,
Glycerol: 6%-9%,
Carbomer: 0.2%-0.4%,
Sodium polyacrylate/Polyethylene Glycol -5m:0.05%-0.09%,
Hyaluronate sodium: 0.25%-0.5%,
Triethanolamine: 0.25%-0.3%,
Butanediol/water/peony root extractive: 0.2%-0.4%,
Double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate: 0.002%-0.005%,
Methylisothiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%-0.004%,
Deionized water: surplus.
Further, described eye mask is grouped into by the group of following weight percentage:
Herba tetragoniae polypeptide: 0.8%,
Glycerol: 8%,
Carbomer: 0.3%,
Sodium polyacrylate/Polyethylene Glycol -5m:0.07%,
Hyaluronate sodium: 0.4%,
Triethanolamine: 0.28%,
Butanediol/water/peony root extractive: 0.3%,
Double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%,
Methylisothiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%,
Deionized water: surplus.
Further, described Herba tetragoniae polypeptide is made up of papain and Fructus Hordei Vulgaris endopeptidase by after neutral protease enzymolysis again Complex enzyme zymohydrolysis be obtained.
Present invention also offers the preparation method of Herba tetragoniae polypeptide, described preparation method is:
Herba tetragoniae is cleaned, and breaks into serosity, adds the sodium chloride solution of the 0.01mol/l of 15 times of Herba tetragoniae amounts, ultrasonic at 40-50 DEG C Ripple extracts 20-30min, and 3500-4500r/min centrifugation takes supernatant, adds citric acid to adjust ph to 3.5-5,3000- 3500r/min centrifugation takes precipitation, washing, 80-85 DEG C of insulation 5-10min, and 3000-3500r/min centrifugation takes precipitation, Add appropriate neutral phosphate buffer solution to be completely dissolved precipitation, add neutral protease, enzymolysis 5-8h at 45-50 DEG C, 70 DEG C enzyme denaturing 5min, adds citric acid to adjust ph to 4.6-5.6, adds compound enzyme, digests 6-8h, 85 DEG C of enzyme denaturing at 43-50 DEG C 10min, using ultrafiltration membrance filter, separates and obtains Herba tetragoniae polypeptide.
Further, the enzyme activity of neutral protease is 50000u/g, and the enzyme activity of papain and Fructus Hordei Vulgaris endopeptidase is 3000-4000u/g.
Further, the enzyme concentration of neutral protease is 3%-5%.
Further, the enzyme concentration of compound enzyme is 4%-8%.
Further, in compound enzyme, the ratio of papain and Fructus Hordei Vulgaris endopeptidase is 1.5:1.
Further, the molecular weight of the Herba tetragoniae polypeptide that described preparation method is obtained is 500da-5000da.
Beneficial effect: the invention provides a kind of eye mask containing Herba tetragoniae polypeptide, add Herba tetragoniae polypeptide, molecular weight in eye mask For 500da-5000da it is easy to be absorbed by the skin, only not good moistening effect, additionally it is possible to help repair tissue to damage, delays The edema of solution eye, eye pouch problem, tightening skin and removing wrinkles.The wetting agents such as glycerol, hyaluronate sodium, butanediol are also contained in facial film, sweet Oil can keep the skin wet to keratodermatitis, adjusts skin sense;Hyaluronate sodium penetrates readily through skin, is deep to reach into skin corium and ties with water Close, keep the moisture of absorbable in the air while moisture of skin, play effect of dual moisturizing water lock, it can also improve office The microcirculation of portion's skin and alimentation, promote the regeneration of eye part skin cell, and Firm is crease-resistant;Butanediol is that small molecule moisturizing becomes Part, there is moisture-keeping function, also have certain bacteriostasis simultaneously.Also contain peony root extractive in facial film, skin whitening can be made, By fossil pigments Reduction fading in skin, effectively alleviate black eye, also there is antiinflammatory, reducing swelling and alleviating pain, antiallergic, antiviral simultaneously Deng effect, can prevent eye part skin from untoward reaction occurring, assist to alleviate ocular edema.In addition, the present invention has promoted Herba tetragoniae Application, be no longer confined to the application of field of food, have also been enlarged the optional species of plant material used for cosmetic simultaneously.
The following component title occurring in literary composition is inci (international nomenclature cosmetic Ingredient, that is, international cosmetic raw material name) defined title: sodium polyacrylate/Polyethylene Glycol -5m, butanediol/ Water/peony root extractive, double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate and Methylisothiazolinone/iodine propilolic alcohol Butyl mephenesin Carbamate.
Specific embodiment
In order that those skilled in the art more fully understand technical scheme, with reference to embodiment to this Bright technical scheme is described in further detail.
Embodiment 1
Take 500g Herba tetragoniae to clean, break into serosity, add the sodium chloride solution of the 0.01mol/l of 15 times of Herba tetragoniae amounts, at 40 DEG C Ultrasonic extraction 30min, 3500r/min centrifugation takes supernatant, adds citric acid to adjust ph to 4.3,3500r/min centrifugation Separate and take precipitation, washing, 80 DEG C of insulation 8min, 3200r/min centrifugation takes precipitation, adds appropriate neutral phosphate buffer molten Liquid is completely dissolved precipitation, adds 3% neutral protease, digests 8h, 70 DEG C of enzyme denaturing 5min at 48 DEG C, adds citric acid to adjust ph To 5.1, add 6% compound enzyme, digest 7h, 85 DEG C of enzyme denaturing 10min at 50 DEG C, using ultrafiltration membrance filter, separating molecular weight is The Herba tetragoniae polypeptide of 500da-5000da is standby.
Embodiment 2
Take 500g Herba tetragoniae to clean, break into serosity, add the sodium chloride solution of the 0.01mol/l of 15 times of Herba tetragoniae amounts, at 50 DEG C Ultrasonic extraction 20min, 4000r/min centrifugation takes supernatant, adds citric acid to adjust ph to 5,3300r/min centrifugation point From taking precipitation, wash, 83 DEG C of insulation 5min, 3000r/min centrifugation takes precipitation, adds appropriate neutral phosphate buffer solution It is completely dissolved precipitation, adds 4% neutral protease, at 50 DEG C, digest 6.5h, 70 DEG C of enzyme denaturing 5min, add citric acid to adjust ph To 5.6, add 8% compound enzyme, digest 6h, 85 DEG C of enzyme denaturing 10min at 47 DEG C, using ultrafiltration membrance filter, separating molecular weight is The Herba tetragoniae polypeptide of 500da-5000da is standby.
Embodiment 3
Take 500g Herba tetragoniae to clean, break into serosity, add the sodium chloride solution of the 0.01mol/l of 15 times of Herba tetragoniae amounts, at 45 DEG C Ultrasonic extraction 25min, 4500r/min centrifugation takes supernatant, adds citric acid to adjust ph to 3.5,3000r/min centrifugation Separate and take precipitation, washing, 85 DEG C of insulation 10min, 3500r/min centrifugation takes precipitation, adds appropriate neutral phosphate buffer Solution is completely dissolved precipitation, adds 5% neutral protease, digests 5h, 70 DEG C of enzyme denaturing 5min at 45 DEG C, adds citric acid to adjust Ph to 4.6, adds 4% compound enzyme, digests 8h, 85 DEG C of enzyme denaturing 10min at 43 DEG C, using ultrafiltration membrance filter, separates molecular weight Herba tetragoniae polypeptide for 500da-5000da is standby.
Embodiment 4-10
The Herba tetragoniae polypeptide that embodiment 1-3 is obtained is prepared into eye mask, and embodiment 4-6 is obtained containing embodiment 1-3 respectively Herba tetragoniae polypeptide, embodiment 7-10 contains the Herba tetragoniae polypeptide that embodiment 2 is obtained, and each eye mask formula composition and its percentage by weight are shown in Table 1.
The each composition of table 1 eye mask formula and its percentage by weight
Hyaluronate sodium, sodium polyacrylate/Polyethylene Glycol -5m and glycerol are added in deionized water, homogenizing, add card ripple Nurse, is heated to 90 DEG C of insulated and stirred 30min, vacuum froth breaking, is cooled to less than 40 DEG C, adds triethanolamine, stirs, and adds Butanediol/water/peony root extractive, stirs, and adds double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl different Thiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate, stirs, takes the dish out of the pot.
Embodiment 11 efficacy assessments are tested
The eye mask that embodiment 4-10 is obtained carries out efficacy assessments test, choose 900 25-45 year volunteer tried Test, be divided into 9 groups, every group 100, each 50 of men and women, the eye mask that experimental group 1-7 is obtained using embodiment 4-10 respectively, comparative example 1 Using blank control group eye mask, comparative example 2 uses commercially available eye mask.Using method: apply eye using this eye mask after daily morning and evening face cleaning 15min, 2 times a week, continuously uses 3 months, counts the behaviour in service of each experimenter, it the results are shown in Table 2.
Table 2 eye mask efficacy assessments result of the test
It can be seen from Table 2 that, the eye mask being obtained in the scope of the invention is improving drying near the eyes, microgroove, black eye, eye The skin problem aspect such as bag, edema all can obtain preferable effect, and most subjects are attained by significantly improving, its effect It is better than commercially available eye mask, then contrasts blank, provable Herba tetragoniae polypeptide can largely improve the skin protection effect of eye mask Really.
The invention provides a kind of eye mask containing Herba tetragoniae polypeptide, in eye mask, add Herba tetragoniae polypeptide, molecular weight is low, skin holds Easily absorb, good moistening effect can be played, also have certain treatment at aspects such as tightening skin and removing wrinkles, eye pouch, edema, black eye simultaneously Effect.The wetting agents such as glycerol, hyaluronate sodium, butanediol are also contained in facial film, fine with the use of playing in terms of moisture-keeping crease-shedding Effect moreover it is possible to promote periocualr skin microcirculation.Also peony root extractive is contained in facial film, can by fossil pigments in skin also Former fade, effectively alleviate black eye, also have simultaneously antiinflammatory, reducing swelling and alleviating pain, antiallergic, antiviral etc. effect, eye can be prevented There is untoward reaction in skin, assist to alleviate ocular edema.In addition, the eye mask preparation process is simple of the present invention, raw material is easy to get, Can be applicable.
Above-described is only the preferred embodiment of the present invention it is noted that for those of ordinary skill in the art For, without departing from the concept of the premise of the invention, some deformation can also be made and improve, these broadly fall into the present invention Protection domain.

Claims (9)

1. a kind of eye mask containing Herba tetragoniae polypeptide is it is characterised in that percentage composition by weight is composed of the following components:
Herba tetragoniae polypeptide: 0.4%-1%,
Glycerol: 6%-9%,
Carbomer: 0.2%-0.4%,
Sodium polyacrylate/Polyethylene Glycol -5m:0.05%-0.09%,
Hyaluronate sodium: 0.25%-0.5%,
Triethanolamine: 0.25%-0.3%,
Butanediol/water/peony root extractive: 0.2%-0.4%,
Double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate: 0.002%-0.005%,
Methylisothiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%-0.004%,
Deionized water: surplus.
2. a kind of eye mask containing Herba tetragoniae polypeptide according to claim 1 is it is characterised in that percentage composition is by following by weight Group is grouped into:
Herba tetragoniae polypeptide: 0.8%,
Glycerol: 8%,
Carbomer: 0.3%,
Sodium polyacrylate/Polyethylene Glycol -5m:0.07%,
Hyaluronate sodium: 0.4%,
Triethanolamine: 0.28%,
Butanediol/water/peony root extractive: 0.3%,
Double imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%,
Methylisothiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate: 0.003%,
Deionized water: surplus.
3. a kind of eye mask containing Herba tetragoniae polypeptide according to claim 1 and 2 it is characterised in that described Herba tetragoniae polypeptide by It is obtained by the complex enzyme zymohydrolysis that papain and Fructus Hordei Vulgaris endopeptidase form after property protease hydrolyzed again.
4. a kind of eye mask containing Herba tetragoniae polypeptide according to claim 3 is it is characterised in that the preparation side of described Herba tetragoniae polypeptide Method is:
Herba tetragoniae is cleaned, and breaks into serosity, adds the sodium chloride solution of the 0.01mol/l of 15 times of Herba tetragoniae amounts, at 40-50 DEG C, ultrasound wave carries Take 20-30min, 3500-4500r/min centrifugation takes supernatant, add citric acid to adjust ph to 3.5-5,3000-3500r/ Min centrifugation takes precipitation, washing, 80-85 DEG C of insulation 5-10min, and 3000-3500r/min centrifugation takes precipitation, adds suitable Amount neutral phosphate buffer solution is completely dissolved precipitation, adds neutral protease, digests 5-8h, 70 DEG C of enzyme denaturing at 45-50 DEG C 5min, adds citric acid to adjust ph to 4.6-5.6, adds compound enzyme, digest 6-8h, 85 DEG C of enzyme denaturing 10min at 43-50 DEG C, Using ultrafiltration membrance filter, separate and obtain Herba tetragoniae polypeptide.
5. preparation method according to claim 4 it is characterised in that neutral protease enzyme activity be 50000u/g, Fructus Chaenomeliss The enzyme activity of protease and Fructus Hordei Vulgaris endopeptidase is 3000-4000u/g.
6. preparation method according to claim 4 is it is characterised in that the enzyme concentration of neutral protease is 3%-5%.
7. preparation method according to claim 4 is it is characterised in that the enzyme concentration of compound enzyme is 4%-8%.
8. preparation method according to claim 7 is it is characterised in that papain and Fructus Hordei Vulgaris endopeptidase in compound enzyme Ratio is 1.5:1.
9. preparation method according to claim 4 it is characterised in that described preparation method be obtained Herba tetragoniae polypeptide molecule Measure as 500da-5000da.
CN201610882773.6A 2016-10-08 2016-10-08 Retina containing new zealand spinach polypeptide Pending CN106344426A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107519093A (en) * 2017-09-11 2017-12-29 广州聚注通用技术研究院有限公司 A kind of crease-resistant eye mask

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860961A (en) * 2012-09-24 2013-01-09 彭再辉 Eye pad essence containing peony root extracts and preparation method for eye pad essence
KR20130083991A (en) * 2012-01-16 2013-07-24 박승림 Production of fermented sauce from wild herbs and vegetables protein
CN103356993A (en) * 2012-04-06 2013-10-23 中国科学院大连化学物理研究所 Application of collagen peptide in preparation of blood lipid lowering medicaments and health-care products
CN105232352A (en) * 2015-10-30 2016-01-13 中山卡丝生物科技有限公司 Polypeptide compound for removing wrinkles in eyes and preparation method of polypeptide compound

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130083991A (en) * 2012-01-16 2013-07-24 박승림 Production of fermented sauce from wild herbs and vegetables protein
CN103356993A (en) * 2012-04-06 2013-10-23 中国科学院大连化学物理研究所 Application of collagen peptide in preparation of blood lipid lowering medicaments and health-care products
CN102860961A (en) * 2012-09-24 2013-01-09 彭再辉 Eye pad essence containing peony root extracts and preparation method for eye pad essence
CN105232352A (en) * 2015-10-30 2016-01-13 中山卡丝生物科技有限公司 Polypeptide compound for removing wrinkles in eyes and preparation method of polypeptide compound

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107519093A (en) * 2017-09-11 2017-12-29 广州聚注通用技术研究院有限公司 A kind of crease-resistant eye mask

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Address before: 510370 Guangdong province Guangzhou City Creek Road in Panlong industrial zone of Liwan District dragon two friends of a 6 storey industrial building

Applicant before: Guangzhou Danqi Daily Chemical Factory Co., Ltd.

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170125