CN106344424A - Sun-proof, moisturizing and anti-aging amino acid cosmetic - Google Patents

Sun-proof, moisturizing and anti-aging amino acid cosmetic Download PDF

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Publication number
CN106344424A
CN106344424A CN201610768736.2A CN201610768736A CN106344424A CN 106344424 A CN106344424 A CN 106344424A CN 201610768736 A CN201610768736 A CN 201610768736A CN 106344424 A CN106344424 A CN 106344424A
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percent
amino acid
cosmetic
proof
moisturizing
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CN201610768736.2A
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Chinese (zh)
Inventor
金基洙
金荣熙
卢勇
金庚泰
朴智浩
陈秀玉
包智楠
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100 Landes Biochemistry (haimen) Co Ltd
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100 Landes Biochemistry (haimen) Co Ltd
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Priority to CN201610768736.2A priority Critical patent/CN106344424A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a sun-proof, moisturizing and anti-aging amino acid cosmetic. The cosmetic comprises an amino acid composition and cosmetic base materials, wherein the amino acid composition accounts for 18 to 25 percent of the total mass of the cosmetic; the amino acid composition comprises the following materials in weight percent: 2.0 to 3.0 percent of lysine, 0.5 to 1.1 percent of histidine, 6 to 7 percent of arginine, 5 to 6 percent of aspartic acid, 7 to 8 percent of threonine, 12 to 13 percent of serine, 12 to 13 percent of glutamic acid, 8 to 9 percent of proline, 5 to 6 percent of glycine, 4 to 5 percent of alanine, 5 to 6 percent of valine, 0.5 to 1.1 percent of methionine, 2 to 3 percent of isoleucine, 6 to 7 percent of leucine, 2 to 3 percent of tyrosine, 1 to 2 percent of phenylalanine, and 15 to 16 percent of cysteine. The cosmetic is prepared through biological natures and unique nutritional ingredients of various amino acids and other cosmetic base materials, has a good synergistic effect after combination, has an obvious curative effect, has a protection effect on skin, is safe, and belongs to nature biological extract composition with certain sun-proof, moisturizing and anti-aging effects on skin.

Description

A kind of sun-proof, moisturizing, the aminoacid cosmetics of defying age
Technical field
The present invention relates to cosmetic technical field, specifically a kind of sun-proof, moisturizing, the aminoacid cosmetics of defying age.
Background technology
Skin refers to tissue outside muscle for the body bag, is the maximum organ of human body, so that various tissues and organ in vivo is exempted from Attacked by physical property, mechanicalness, chemical and pathogenic microorganism, be there is protective barrier effect.When skin accepts ultraviolet mistake After degree is exposed to the sun, epidermis cell can be damaged, make skin become drying, make the elastic fiberss in skin corium impaired, produce microgroove.Strong Under strong irradiation, also can cause skin inflammation, burn.Temperature change and pressure that air-conditioning, environmental pollution, Seasonal conversion bring, with And skin aging, metabolism the factor such as slow down and all can cause skin moisture loss, make skin coarse, dim mute, formed dry stricture of vagina, cause all Many skin problem.
Content of the invention
For solving above-mentioned technical problem, the present invention provides a kind of sun-proof, moisturizing, the aminoacid cosmetics of defying age.
The present invention takes technical scheme below: a kind of sun-proof, moisturizing, the aminoacid cosmetics of defying age, including aminoacid Compositionss and cosmetic base, described amino acid composition accounts for the 18-25% of cosmetics gross mass, according to amino acid composition Weight meter, described amino acid composition is 2.0% ~ 3.0% lysine, 0.5% ~ 1.1% histidine, 6% ~ 7% arginine, 5% ~ 6% day Winter propylhomoserin, 7% ~ 8% threonine, 12% ~ 13% serine, 12% ~ 13% glutamic acid, 8% ~ 9% proline, 5% ~ 6% glycine, 4% ~ 5% Alanine, 5% ~ 6% L-Valine, 0.5% ~ 1.1% Methionine, 2% ~ 3% isoleucine, 6% ~ 7% leucine, 2% ~ 3% tyrosine, 1% ~ 2% phenylalanine, 15% ~ 16% cysteine.
Emollient, wetting agent and preservative is contained in described cosmetic base.
The dosage form of above-mentioned cosmetics is emulsion, cream or essence.
The invention has the advantage that utilizing lysine, histidine, arginine, aspartic acid, threonine, serine, paddy ammonia Acid, proline, glycine, alanine, L-Valine, Methionine, isoleucine, leucine, tyrosine, phenylalanine and half Guang In propylhomoserin, excellent biological nature and unique nutritional labeling, coordinate other cosmetic base raw materials to be prepared from, and assist after combination Good with effect, curative effect is obvious.Skin is played a protective role, is a kind of safe, have necessarily sun-proof, moisturizing, anti-to skin The natural biological extractive composition of old and feeble effect, meets the requirement to cosmetics safety for the people.
Specific embodiment
With reference to embodiment, technical scheme is further described.
In cosmetics of the present invention, the effect of each aminoacid is as follows:
Lysine: human development can be promoted, strengthen immunologic function, improve central nervous tissue function, prevent bone-loss, increase Collagen protein.
Histidine: promote the absorption of ferrum, thus can be used for preventing and treating anemia.Histidine can reduce gastric acidity, relaxes gastrointestinal The pain of operation, mitigates trimester of pregnancy vomiting and scorching hot sense, and the digestive tract that suppression is caused by vegetative nerve anxiety festers, right Anaphylactic disease, such as asthma etc. are also powerful.Additionally, the expansible blood vessel of histidine, reduce blood pressure, clinically be used for angina pectoriss, The treatment of the diseases such as cardiac insufficiency.In patient with rheumatoid arthritis blood, histidine content substantially reduces, after histidine Find its grip, walk and all take a favorable turn with indexs such as erythrocyte sedimentation rates.
Arginine: arginine is that the constituent of one of ornithine cycle has extremely important physiological function.Eat more Arginine, can increase the activity of arginase in liver, contribute to for the ammonia in blood being changed into carbamide and excrete out.Institute So that, to hyperammonemia, hepatic dysfunction etc. is all powerful for arginine
Aspartic acid: for resisting age of skin, someone is by Phenylalanine with ascorbic acid compatibility or with aspartic acid and its derivant With vitamin day b6Compatibility uses, and all can suppress skin aging.It can be used as k+、mg2+The carrier Cardiomyocytes conveying electrolysis of ion Matter, thus improving myocardium shrinkage function, reducing oxygen consumption simultaneously, in coronary artery circulation obstacle anoxia, having protection to cardiac muscle Effect.It participates in ornithine cycle, promotes oxygen and carbon dioxide to generate carbamide, reduces the amount of nitrogen and carbon dioxide in blood, increases Strong liver function, allaying tiredness.
Threonine: for amino acid, promote protein synthesis and deposition.Threonine shortage can suppress immunoglobulin And the generation of t.b lymphocyte, and then affect immunologic function.There is obvious impact on body fat metabolism, it can promote phosphorus matter Synthesis and fatty acid oxidation.
Serine: serine can increase epidermis cell vigor and moisturizing, delay skin aging.It is in fat and fatty acid Play in the growth of metabolism and muscle and act on, because it contributes to the generation of immunoglobulin and antibody, maintain health Immune system be also required to serine.The sheath of manufacture processing, muscular tissue and encirclement neurocyte in cell membrane for the serine All play in synthesis and act on.
Glutamic acid: contain substantial amounts of glutamic acid in the epidermis of people, glutamic acid can be converted into α ketopyrrolidine 5 carboxylic acid (pca) be skin nature moisturizing factor, its insulating power exceeds well over glycerol, the third two liquor-saturated, Pyrusussuriensiss are liquor-saturated etc..P c a has height Water absorption, and nontoxic, non-stimulated, be the important component of modern skin protection, cosmetic hair care.There is obvious moisturizing to skin Effect.As containing in ascorbic acid second phosphoric acid vinegar (i) sodium and polynary liquor-saturated cosmetics, increased a small amount of glycerol polyoxy second Alkene ether pyroglutamic acid different Hard Fat two is dead drunk, that is, constitute high-grade protective skin cream class.
Proline: for Branchamin.One of amino acid big transfusion raw material.Lack for malnutrition, protein Disease, Severe gastrointestinal tract disease, the Protein intake of scald and surgical site infections.The proline of accumulation is except as plant cytoplasm Outside interior osmotic adjustment, also in stabilate macromolecular structure, reduce cellular acid, release ammonia poison and as energy sink tune The aspects such as ganglion cell's oxidation-reduction potential play an important role.
Glycine: there is acidity and basic functionality in the molecule simultaneously, ionizable in water, have very strong hydrophilic Property, belong to polar amino acid, be dissolved in polar solvent, and be insoluble in non-polar solven, and there is higher boiling point and fusing point, Glycine can be made to assume different molecular conformations by the regulation of aqueous solution Acidity of Aikalinity.
Alanine: prevention renal calculuss, the metabolism of assistance glucose, help mitigation hypoglycemia, improve body energy.
L-Valine: the promotion body that works together with it and other two kinds of high-purity amino acids (isoleucine and leucine) is normal Growth, repair tissue, adjust blood glucose, and the energy of needs is provided.When participating in fierce physical exertion, L-Valine can give muscle There is provided extra energy production glucose, to prevent muscle weakness.It also helps remove unnecessary nitrogen (potentially poison from liver Element), and the nitrogen of somagenic need is transported each position.
Methionine: if methionine lacks may result in vivo protein biosynthesis block, cause body damage.First sulfur Propylhomoserin can resist hepatitis interstitialis chronica, fatty liver and various acute, chronic, viral, bilious liver.Cardiac muscle, antidepressant can also be protected Disease, blood pressure lowering, gas defence toxic removing.Methylate and play an important role in biosynthesis and metabolism in vivo.Methionine is body Interior most important methyl donor, a lot of nitrogen substances methionine in biosynthesiss is provided on methyl such as creatine, epiphysin, kidney Parathyrine, carnitine, neosine, choline .alpha.-Methylhistamine, first Yan amine etc..Equally methylate in terms of the modification processing of protein and nucleic acid Also extremely important.
Isoleucine: leucic effect includes cooperation together with isoleucine and L-Valine and repairs muscle, controls blood glucose, And provide energy to bodily tissue.It also improves the yield of growth hormone, and helps the interior fat that burns.Leucine, different bright ammonia Acid and L-Valine are all branched-chain amino acid, and they help lend some impetus to the muscle recovery after training.
Leucine: leucine can accelerate the metabolism of Skin Cell, promotes skin tissue regeneration and healing.Leucine It is a kind of maximally effective branched-chain amino acid, can effectively prevent muscle loss.Increasing glucose can prevent muscular tissue impaired, Therefore it is particularly suitable for body-builders.Because it is easily converted to glucose, therefore leucine contributes to adjusting blood glucose water Flat.The people that leucine lacks occurs similar hypoglycemic symptom, such as has a headache, dizzy, and fatigue is depressed, mental disorder, and irritability Deng.
Tyrosine: tyrosine is the catalytic substrate of tryrosinase monophenolase function, is ultimately formed excellent melanocyte and pheomelanin Primary raw material.In skin-lightening cosmetic research and development, can be similar with the tryrosinase structure of tyrosine competition by research synthesis Thing also can suppress the generation of melanocyte effectively.Amino acid transfusion and the raw material of amino acid composite preparation, make nutritional supplement.Treatment The disease such as poliomyelitis and property nuclearity encephalitis, hyperthyroidism.Also it is used for manufacturing diiodotyrosine, dibromotyrosine and l- The raw material of DOPA.
Phenylalanine: also known as phenylacetic acid.Phenylacetic acid is the intermediate of the organic synthesiss such as medicine, pesticide, spice.In medicine For the production of the medicine such as penicillin, bendazol in industry.Phenylacetic acid obtains alpha-chloro ethyl phenylacetate through chlorination, esterification, uses In the production of phenthoate dimephenthoate cidial and ethyl phenthoate dimephenthoate cidial, both pesticide are broad-spectrum organic insecticides.Phenylacetic acid is also pesticide in itself Plant growth substance.Phenylacetic acid is widely present in Fructus Vitis viniferae, Fructus Fragariae Ananssae, cocoa, green tea, Mel etc..Phenylacetic acid is in low concentration There is sweet honey flavour, in below 1ppm, still there is sweet taste, be a kind of important fragrance component.Phenylacetic acid also has very strong sterilization Effect.
Partly look into the distance propylhomoserin: skin can be made to keep repellence that is tender ruddy in vain and increasing skin.With photochromic pigment with acidity amino Sour compatibility, can improve the function of skin, prevent skin aging.Cysteine is unstable compound, easy oxidoreduction, Mutually change with cystine.Also mercapturic acid can be condensed into poisonous aromatic compound and play Detoxication.
Embodiment 1:
A kind of sun-proof, moisturizing, the aminoacid emulsion of defying age, Ju Ti Pei Fang is (by weight percentage): (the containing of each aminoacid Amount is the percentage composition according to amino acid composition gross weight meter, and amino acid composition accounts for the 18% of cosmetics gross weight)
Lysine 2.4%
Histidine 0.7%
Arginine 6.5%
Aspartic acid 5.2%
Threonine 7.4%
Serine 12.5 %
Glutamic acid 12.4%
Proline 8.6%
Glycine 5.7%
Alanine 4.4%
L-Valine 5.6%
Methionine 1.0%
Isoleucine 2.5%
Leucine 6.4%
Tyrosine 2.5%
Phenylalanine 1.2%
Cysteine 15%
1,3 butylene glycol (wetting agent) 5%
Peg-40 (emollient) 2%
Xanthan gum (emulsifying agent) 2%
Glycerol (emollient) 10%
Edta 2na(preservative) 0.05%
Ethylhexyl palmitate (solvent) 4%
Citric acid (preservative) 0.03%
Deionized water (solvent) is added to 100%.
Embodiment 2:
A kind of sun-proof, moisturizing, the aminoacid essence of defying age, Ju Ti Pei Fang is (by weight percentage): (the containing of each aminoacid Amount is the percentage composition according to amino acid composition gross weight meter, and amino acid composition accounts for the 25% of cosmetics gross weight)
Lysine 2.4%
Histidine 0.7%
Arginine 6.5%
Aspartic acid 5.2%
Threonine 7.4%
Serine 12.5 %
Glutamic acid 12.4%
Proline 8.6%
Glycine 5.7%
Alanine 4.4%
L-Valine 5.6%
Methionine 1.0%
Isoleucine 2.5%
Leucine 6.4%
Tyrosine 2.5%
Phenylalanine 1.2%
Cysteine 15 %
1,3 butylene glycol (wetting agent) 2%
Hyaluronate sodium (wetting agent) 0.1%
Princepia utilis oil (emollient) 0.2%
Antibacterial (preservative) 0.5%
Deionized water (solvent) is added to 100%.
Embodiment 3:
A kind of sun-proof, moisturizing, the aminoacid cream of defying age, Ju Ti Pei Fang is (by weight percentage):
(content of each aminoacid is the percentage composition according to amino acid composition gross weight meter, and amino acid composition accounts for cosmetics The 20% of gross weight)
Lysine 2.4%
Histidine 0.7%
Arginine 6.5%
Aspartic acid 5.2%
Threonine 7.4%
Serine 12.5 %
Glutamic acid 12.4%
Proline 8.6%
Glycine 5.7%
Alanine 4.4%
L-Valine 5.6%
Methionine 1.0%
Isoleucine 2.5%
Leucine 6.4%
Tyrosine 2.5%
Phenylalanine 1.2%
Cysteine 15 %
1,3 butylene glycol (wetting agent) 3%
Silicon dioxide (emulsifying agent) 1%
Xanthan gum (emulsifying agent) 2%
Hydrogenated vegetable oil (emollient) 2%
Glycerol (emollient) 10%
Phenoxyethanol (preservative) 0.06%
Citric acid (preservative) 0.03%
Deionized water (solvent) is added to 100%.

Claims (3)

1. the aminoacid cosmetics of a kind of sun-proof, moisturizing, defying age are it is characterised in that include amino acid composition and cosmetics Substrate, described amino acid composition accounts for the 18-25% of cosmetics gross mass, according to the gross weight meter of amino acid composition, described ammonia Base acid composition is 2.0% ~ 3.0% lysine, 0.5% ~ 1.1% histidine, 6% ~ 7% arginine, 5% ~ 6% aspartic acid, 7% ~ 8% Soviet Union Propylhomoserin, 12% ~ 13% serine, 12% ~ 13% glutamic acid, 8% ~ 9% proline, 5% ~ 6% glycine, 4% ~ 5% alanine, 5% ~ 6% figured silk fabrics Propylhomoserin, 0.5% ~ 1.1% Methionine, 2% ~ 3% isoleucine, 6% ~ 7% leucine, 2% ~ 3% tyrosine, 1% ~ 2% phenylalanine, 15% ~ 16% cysteine.
2. the aminoacid cosmetics of a kind of sun-proof, moisturizing according to claim 1, defying age are it is characterised in that describedization Emollient, wetting agent and preservative is contained in cosmetic substrate.
3. the aminoacid cosmetics of a kind of sun-proof, moisturizing according to claim 1, defying age are it is characterised in that describedization The dosage form of cosmetic is emulsion, cream or essence.
CN201610768736.2A 2016-08-31 2016-08-31 Sun-proof, moisturizing and anti-aging amino acid cosmetic Pending CN106344424A (en)

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Cited By (12)

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Publication number Priority date Publication date Assignee Title
CN106880556A (en) * 2017-03-27 2017-06-23 钱凤英 A kind of non-pigmented composite skin care product of perfume-free and preparation method thereof
CN107822910A (en) * 2017-11-16 2018-03-23 北京工商大学 Adjust the amino acid composition of skin surface pH value and its application in cosmetics
CN107898689A (en) * 2017-12-05 2018-04-13 佛山微赢电子商务有限公司 A kind of the painting type water laser accunputure and preparation method of zero addition
CN108403480A (en) * 2018-04-10 2018-08-17 广州赛莱拉干细胞科技股份有限公司 Composition containing Ovshinsky marine algae extract and its application in cosmetics
CN108992368A (en) * 2018-08-21 2018-12-14 上海儿童营养中心有限公司 A kind of liposome of bionical vernix caseosa, preparation method and application
CN110090169A (en) * 2019-05-27 2019-08-06 广州瑞诗生物科技有限公司 A kind of hyaluronic acid nti-freckle gel
CN110327243A (en) * 2019-08-15 2019-10-15 武汉洛园生物科技有限公司 A kind of clean mousse composition of the amino acid of plant origin and preparation method
CN112188891A (en) * 2018-04-04 2021-01-05 佛罗里达大学研究基金会公司 Composition for treating skin
CN112353716A (en) * 2020-12-18 2021-02-12 现代百朗德生物科技(江苏)有限公司 Composition with effects of moisturizing and resisting aging and preparation method thereof
CN113133952A (en) * 2021-04-30 2021-07-20 上海禾雅堂医疗科技有限公司 Composition with skin-care and nutrition functions and preparation method thereof
CN113509403A (en) * 2021-07-28 2021-10-19 杭州拾珍医疗器械有限公司 In-vitro energy supply substance and raw material suitable for skin collagen synthesis and preparation method thereof
CN116348087A (en) * 2020-09-29 2023-06-27 联合利华知识产权控股有限公司 Personal care compositions comprising amino acids

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106880556A (en) * 2017-03-27 2017-06-23 钱凤英 A kind of non-pigmented composite skin care product of perfume-free and preparation method thereof
CN107822910A (en) * 2017-11-16 2018-03-23 北京工商大学 Adjust the amino acid composition of skin surface pH value and its application in cosmetics
CN107822910B (en) * 2017-11-16 2018-11-06 北京工商大学 The amino acid composition for adjusting skin surface pH value and its application in cosmetics
CN107898689A (en) * 2017-12-05 2018-04-13 佛山微赢电子商务有限公司 A kind of the painting type water laser accunputure and preparation method of zero addition
CN112188891A (en) * 2018-04-04 2021-01-05 佛罗里达大学研究基金会公司 Composition for treating skin
CN108403480A (en) * 2018-04-10 2018-08-17 广州赛莱拉干细胞科技股份有限公司 Composition containing Ovshinsky marine algae extract and its application in cosmetics
CN108992368A (en) * 2018-08-21 2018-12-14 上海儿童营养中心有限公司 A kind of liposome of bionical vernix caseosa, preparation method and application
CN110090169A (en) * 2019-05-27 2019-08-06 广州瑞诗生物科技有限公司 A kind of hyaluronic acid nti-freckle gel
CN110327243A (en) * 2019-08-15 2019-10-15 武汉洛园生物科技有限公司 A kind of clean mousse composition of the amino acid of plant origin and preparation method
CN116348087A (en) * 2020-09-29 2023-06-27 联合利华知识产权控股有限公司 Personal care compositions comprising amino acids
CN112353716A (en) * 2020-12-18 2021-02-12 现代百朗德生物科技(江苏)有限公司 Composition with effects of moisturizing and resisting aging and preparation method thereof
CN113133952A (en) * 2021-04-30 2021-07-20 上海禾雅堂医疗科技有限公司 Composition with skin-care and nutrition functions and preparation method thereof
CN113509403A (en) * 2021-07-28 2021-10-19 杭州拾珍医疗器械有限公司 In-vitro energy supply substance and raw material suitable for skin collagen synthesis and preparation method thereof

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