CN106317030B - 一种4-吲哚基香豆素衍生物及其制备方法和应用 - Google Patents
一种4-吲哚基香豆素衍生物及其制备方法和应用 Download PDFInfo
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- CN106317030B CN106317030B CN201610713047.1A CN201610713047A CN106317030B CN 106317030 B CN106317030 B CN 106317030B CN 201610713047 A CN201610713047 A CN 201610713047A CN 106317030 B CN106317030 B CN 106317030B
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- cumarin
- indyl
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- coumarin derivative
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CN201610713047.1A CN106317030B (zh) | 2016-08-24 | 2016-08-24 | 一种4-吲哚基香豆素衍生物及其制备方法和应用 |
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CN201610713047.1A CN106317030B (zh) | 2016-08-24 | 2016-08-24 | 一种4-吲哚基香豆素衍生物及其制备方法和应用 |
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CN106317030A CN106317030A (zh) | 2017-01-11 |
CN106317030B true CN106317030B (zh) | 2018-11-30 |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2018335838B2 (en) * | 2017-09-20 | 2022-06-30 | Lead Discovery Center Gmbh | Coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer |
WO2024044616A1 (en) * | 2022-08-23 | 2024-02-29 | University Of Florida Research Foundation, Inc. | Compositions and methods of making the compositions |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101906090A (zh) * | 2010-06-04 | 2010-12-08 | 中科院广州化学有限公司 | 一种3,4-二氢-4-芳基香豆素类化合物及其制备方法和用途 |
CN101967135A (zh) * | 2010-09-16 | 2011-02-09 | 中科院广州化学有限公司 | 一种4-芳基香豆素类化合物及其制备方法和用途 |
CN105801543A (zh) * | 2016-04-18 | 2016-07-27 | 中国药科大学 | 4-芳香胺-香豆素衍生物及其制备方法和医药用途 |
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2016
- 2016-08-24 CN CN201610713047.1A patent/CN106317030B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101906090A (zh) * | 2010-06-04 | 2010-12-08 | 中科院广州化学有限公司 | 一种3,4-二氢-4-芳基香豆素类化合物及其制备方法和用途 |
CN101967135A (zh) * | 2010-09-16 | 2011-02-09 | 中科院广州化学有限公司 | 一种4-芳基香豆素类化合物及其制备方法和用途 |
CN105801543A (zh) * | 2016-04-18 | 2016-07-27 | 中国药科大学 | 4-芳香胺-香豆素衍生物及其制备方法和医药用途 |
Non-Patent Citations (3)
Title |
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Christian Bailly,等.Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins.《J. Med. Chem.》.2003,第46卷 * |
Olga G. Ganina,等.ChemInform Abstract: Palladium‐Catalyzed Reactions of 4‐(Trifluoromethylsulfonyloxy)coumarins with Amides and NH‐Heterocycles.《Synthesis》.2010,第21卷 * |
Olga G. Ganina,等.Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor.《Bioorganic & Medicinal Chemistry》.2008,第16卷 * |
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