CN106290827B - Luminescent material test strips joint-detection intelligence system and detection method are forwarded in one kind - Google Patents

Luminescent material test strips joint-detection intelligence system and detection method are forwarded in one kind Download PDF

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Publication number
CN106290827B
CN106290827B CN201610560956.6A CN201610560956A CN106290827B CN 106290827 B CN106290827 B CN 106290827B CN 201610560956 A CN201610560956 A CN 201610560956A CN 106290827 B CN106290827 B CN 106290827B
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bottle
test
valve
luminescent material
test paper
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CN106290827A (en
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陶少强
李玉峰
张士伟
张斌
王晓杨
杨彦齐
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Anhui National Science Biotechnology Co., Ltd.
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Anhui National Science Biotechnology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Include elevating mechanism, support, cleaning lid, test paper clamping plate, shell fragment, test bottle, discharging tube, feed tube, cleaning pipe, sample bottle and sewer pipe present invention is disclosed luminescent material test strips joint-detection intelligence system is forwarded in one kind.The advantage of the invention is that easy to use, installation operation step process is required to, reduces difficulty of test, while by equipment automation control, improves the precision of test, it helps improve testing efficiency.

Description

Luminescent material test strips joint-detection intelligence system and detection method are forwarded in one kind
Technical field
The present invention relates to the system for carrying out chromatographing detection to test strips made of collaurum (PCT).
Background technology
Although carrying out clinical detection currently with upper forwarding luminescent material test strips very to have popularized, currently with When upper forwarding luminescent material test strips carry out chromatography and realized, all it is to need staff manually operated, not only increases experiment process In uncontrollability, from exist influence test accuracy hidden danger, and can only one sample of a sample detect one by one, it is difficult to It is multiple to detect simultaneously.
The content of the invention
The technical problems to be solved by the invention are to realize that one kind convenient, fast and accurate can carry out chromatographing intelligent inspection The system of survey.
To achieve these goals, the technical solution adopted by the present invention is:The joint inspection of luminescent material test strips is forwarded in one kind Intelligence system is surveyed, parallel bracket is made up of two parallel support bars, on the horizontal fixed elevating mechanism of parallel bracket, wherein one The support bar lower surface is provided with equidistantly fixed test paper clamping plate vertically, and each test paper clamping plate is provided with least two and used In the shell fragment of clamping test paper, another support bar lower surface is provided with equidistantly fixed cleaning lid vertically;
Row's test bottle is provided with below the parallel bracket, the test bottle is fixed on translation mechanism, the test bottle Quantity with cleaning lid, test paper clamping plate quantity it is identical, and the fixed position of test bottle with cleaning cover or test paper clamping plate rotate to Position is mutually corresponding when above test bottle;
Each test bottle is provided with the sample bottle that an installation site is higher than test bottle, and the sample bottle passes through feed liquor Pipe connects test bottle, and the test bottle is connected with cleaning pipe, and the cleaning pipe connects water source, the test bottle bottom connection through pump Have a discharging tube, the sample bottle bottom is connected with sewer pipe, and the discharging tube is provided with tapping valve, the feed tube be provided with into Liquid valve, the cleaning pipe are provided with purge valve, and the sewer pipe is provided with waist valve.
The translation mechanism includes track, installs sliding block in orbit, and the test bottle is fixed on sliding block, the rail Rack is provided with road, is fixed with stepper motor on the sliding block, the wheel and rack engagement on the stepper motor output shaft, institute State track both ends and be provided with gag lever post, the Hall sensor of measurement rotary torsion is provided with the stepper motor.
The sample bottle is provided with scale, and sample bottle is provided with bottle cover bracket, the bottle cover bracket be provided with it is each The bottle cap of sample bottle position correspondence, the bottle cover bracket are fixed on lift cylinder, and each bottle cap lower surface is equipped with out Stomata, the venthole are connected through flexible pipe with hot gas source.
The upper forwarding luminescent material test strips joint-detection intelligence system is arranged in thermostatical storehouse, is provided with the thermostatical storehouse Thermoregulation mechanism.
The side of the test paper Boards wall test paper of the upper forwarding luminescent material test strips joint-detection intelligence system is fixed with Laser system, laser system output collection signal to main control unit, the main control unit output image information is to depositing Storage unit and display unit.
The main control unit is provided with clock unit, and the main control unit outputs control signals to pump, tapping valve, feed liquor Valve, purge valve, waist valve, elevating mechanism, stepper motor, hot gas source and lift cylinder, and receive the signal of Hall sensor.
Detection method based on the upper forwarding luminescent material test strips joint-detection intelligence system:
Step 1, start for the first time, elevating mechanism and lift cylinder push, and cleaning lid blocks each test bottle, and bottle cap blocks up Firmly each sample bottle;
Step 2, open liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off into Liquid valve, purge valve and waist valve;
Step 3, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Step 4, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually test paper is fixed on test paper clamping plate, quantitative test sample is injected in sample bottle;
Step 7, start for second, test bottle is moved to below test paper clamping plate;
Step 8, elevating mechanism are pushed, and test paper clamping plate is put into test bottle;
Step 9, after the delay adjustmentses time, elevating mechanism rise, laser system collection test paper image information;
Step 10, test bottle is moved to cleaning lid lower section, elevating mechanism and lift cylinder push, and cleaning lid is blocked each Individual test bottle, bottle cap block each sample bottle;
Step 11, liquid feed valve, purge valve and waist valve are opened, restart pump, clean time rating, closed pump, turn off Liquid feed valve, purge valve and waist valve;
Step 12, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Step 13, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism and lift cylinder rise, and once test terminates.
The advantage of the invention is that it is easy to use, installation operation step process is required to, reduces difficulty of test, is led to simultaneously Equipment automation control is crossed, improves the precision of test, it helps improves testing efficiency.
Brief description of the drawings
The content of every width accompanying drawing expression in description of the invention and the mark in figure are briefly described below:
Fig. 1 is upper forwarding luminescent material test strips joint-detection intelligence system structural representation;
Mark in above-mentioned figure is:1st, elevating mechanism;2nd, parallel bracket;3rd, cleaning lid;4th, test paper clamping plate;5th, shell fragment; 6th, test bottle;7th, discharging tube;8th, feed tube;9th, cleaning pipe;10th, sample bottle;11st, sewer pipe.
Embodiment
As shown in figure 1, upper forwarding luminescent material test strips joint-detection intelligence system include elevating mechanism 1, parallel bracket 2, Clean lid 3, test paper clamping plate 4, shell fragment 5, test bottle 6, discharging tube 7, feed tube 8, cleaning pipe 9, sample bottle 10 and sewer pipe 11.On Forward luminescent material test strips joint-detection intelligence system to be arranged in thermostatical storehouse, be provided with thermoregulation mechanism in thermostatical storehouse, so It can make further control to experimental enviroment by the temperature in regulating thermostatic storehouse, improve experiment reliability and controllability.
System is provided with parallel bracket 2, and parallel bracket 2 is made up of two parallel support bars, the horizontal fixed liter of parallel bracket On descending mechanism 1, wherein a support bar lower surface is provided with equidistantly fixed test paper clamping plate 4, each test paper clamping plate 4 vertically At least two shell fragments 5 for being used to clamp test paper are provided with, another support bar lower surface is provided with equidistantly fixed cleaning vertically Lid 3.
The lower section of support bar is provided with row's test bottle 6, and row's test bottle 6 is fixed on translation mechanism, cleans lid 3 and test paper Position of the clamping plate 4 on two support bars is identical, is adjusted by translation mechanism, can selectivity will be fixed with cleaning lid 3 or The support bar of test paper clamping plate 4 is moved to the top of test bottle 6.
Translation mechanism includes track, installs sliding block in orbit, and test bottle 6 is fixed on sliding block, and tooth is provided with track Bar, is fixed with stepper motor on sliding block, and the wheel and rack engagement on stepper motor output shaft, track both ends are provided with gag lever post, The Hall sensor of measurement rotary torsion is provided with stepper motor.Gag lever post limits the sliding scale of sliding block, recycles Hall to pass Sensor can avoid overexercise, and both coordinate the translation distance for being capable of accurately control slide block.
Wherein support bar lower surface is provided with equidistantly fixed test paper clamping plate 4 vertically, under another support bar Surface is provided with equidistantly fixed cleaning lid 3 vertically, and each test paper clamping plate 4 is provided with least two and is used to clamp test paper Shell fragment 5.
Test bottle 6 is matching used, therefore the quantity of test bottle 6 and cleaning lid 3 with cleaning lid 3, test paper clamping plate 4, with And the quantity of test bottle 6 and the quantity of test paper clamping plate 4 are identical, after each post position adjustment, the fixed bit of test bottle 6 It is mutually corresponding to put position when moving to 6 top of test bottle with cleaning lid 3 or test paper clamping plate 4, i.e., each cleaning lid 3 can be filled in one The bottleneck of individual test bottle 6, each test paper clamping plate 4 can be put into the bottle of a test bottle 6.
Each test bottle 6 is provided with the sample bottle 10 that an installation site is higher than test bottle 6, i.e. liquid in sample bottle 10 Can be by the way that in gravity flowing to test bottle 6, sample bottle 10 connect test bottle 6 by feed tube 8, test bottle 6 is connected with cleaning Pipe 9, cleaning pipe 9 connect water source through pump, and the bottom of test bottle 6 is connected with discharging tube 7, and the bottom of sample bottle 10 is connected with sewer pipe 11, Discharging tube 7 is provided with tapping valve, and feed tube 8 is provided with liquid feed valve, and cleaning pipe 9 is provided with purge valve, and sewer pipe 11 is provided with useless Liquid valve.The above-mentioned preferred flexible pipe of pipeline.
Sample bottle 10 is provided with scale, and convenient use person accurately imports measurement liquid, and sample bottle 10 is provided with bottle cap Support, bottle cover bracket are provided with bottle cap with each position correspondence of sample bottle 10, i.e., the quantity of bottle cap and sample bottle 10, position are equal Identical and correspondingly, bottle cover bracket is fixed on lift cylinder, and each bottle cap lower surface is equipped with venthole, venthole through flexible pipe with Hot gas source connects, and can dry ponding by hot gas source, avoid having influence on result of the test.Sample bottle 10 and test bottle 6 use Transparent vial body, convenient observation.
In order to improve the reliability of capping, bottle cap and the cleaning upper surface of lid 3 pass through spring and lift cylinder, elevating mechanism 1 Connection, lower surface are provided with rubber blanket, so that it is guaranteed that sealing during cleaning.
In order to coordinate whole system work, system is provided with main control unit, and main control unit is provided with clock unit, main Control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, waist valve, elevating mechanism 1, stepper motor, hot gas Source and lift cylinder, and the signal of Hall sensor is received, the test paper of upper forwarding luminescent material test strips joint-detection intelligence system The side that clamping plate 4 fixes test paper is fixed with laser system, and laser system includes generating laser and receives the receiver of reflected light, Laser is launched to each test paper by generating laser, then received by receiver, the test result of needs, laser system can be obtained System output collection signal main control unit output image information to memory cell and display unit, so may be used to main control unit Accurately to record the test paper state after test.
Detection method based on above-mentioned upper forwarding luminescent material test strips joint-detection intelligence system:
Step 1, start for the first time, elevating mechanism 1 and lift cylinder push, and cleaning lid 3 blocks each test bottle 6, bottle Lid blocks each sample bottle 10;(being that cleaning lid 3 is located at the top of test bottle 6 after terminating every time);
Step 2, open liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off into Liquid valve, purge valve and waist valve;
Step 3, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
So as to clean sample bottle 10 and test bottle 6, avoid disturbing;
Step 4, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism 1 and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually test paper is fixed on test paper clamping plate 4, the injection quantitative test sample in sample bottle 10;
Step 7, start for second, test bottle 6 is moved to the lower section of test paper clamping plate 4;
Step 8, elevating mechanism 1 are pushed, and test paper clamping plate 4 is put into test bottle 6;
Step 9, after the delay adjustmentses time, elevating mechanism 1 rises, laser system collection test paper image information;
Step 10, cleaning lid 3 is moved to the top of test bottle 6, elevating mechanism 1 and lift cylinder are pushed, and cleaning lid 3 is blocked Each test bottle 6, bottle cap block each sample bottle 10;
Step 11, liquid feed valve, purge valve and waist valve are opened, restart pump, clean time rating, closed pump, turn off Liquid feed valve, purge valve and waist valve;
Step 12, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
So as to be cleaned to sample bottle 10 and test bottle 6, avoid disturbing, avoid interfering to testing next time;
Step 13, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism 1 and lift cylinder rise, and once test terminates.
All operations of intelligent automaticization, specification testing process, accurate test result, and facilitate staff Use, multigroup sample can be tested under same environment simultaneously, it is convenient to compare and record.
The present invention is exemplarily described above in conjunction with accompanying drawing, it is clear that present invention specific implementation is not by aforesaid way Limitation, as long as the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress is employed, or without changing Enter and the design of the present invention and technical scheme are directly applied into other occasions, within protection scope of the present invention.

Claims (7)

1. luminescent material test strips joint-detection intelligence system is forwarded in one kind, it is characterised in that:
Parallel bracket is made up of two parallel support bars, on the horizontal fixed elevating mechanism of parallel bracket, wherein a branch Strut lower surface is provided with equidistantly fixed test paper clamping plate vertically, and each test paper clamping plate is provided with least two and is used to clamp The shell fragment of test paper, another support bar lower surface are provided with equidistantly fixed cleaning lid vertically;
Row's test bottle is provided with below the parallel bracket, the test bottle is fixed on translation mechanism, the number of the test bottle Amount is identical with the quantity of cleaning lid, test paper clamping plate, and the fixed position of test bottle is covered with cleaning or test paper clamping plate rotates to test Position is mutually corresponding during bottle top;
Each test bottle is provided with the sample bottle that an installation site is higher than test bottle, and the sample bottle is connected by feed tube Logical test bottle, the test bottle are connected with cleaning pipe, and the cleaning pipe connects water source through pump, and the test bottle bottom is connected with row Liquid pipe, the sample bottle bottom are connected with sewer pipe, and the discharging tube is provided with tapping valve, and the feed tube is provided with feed liquor Valve, the cleaning pipe are provided with purge valve, and the sewer pipe is provided with waist valve.
2. upper forwarding luminescent material test strips joint-detection intelligence system according to claim 1, it is characterised in that:It is described flat Telephone-moving structure includes track, installs sliding block in orbit, and the test bottle is fixed on sliding block, and rack is provided with the track, It is fixed with stepper motor on the sliding block, the wheel and rack engagement on the stepper motor output shaft, the track both ends are set Limited location bar, the interior Hall sensor for being provided with measurement rotary torsion of the stepper motor.
3. upper forwarding luminescent material test strips joint-detection intelligence system according to claim 2, it is characterised in that:The sample Product bottle is provided with scale, and sample bottle is provided with bottle cover bracket, and the bottle cover bracket is provided with and each sample bottle position correspondence Bottle cap, the bottle cover bracket is fixed on lift cylinder, and each bottle cap lower surface is equipped with venthole, the venthole It is connected through flexible pipe with hot gas source.
4. upper forwarding luminescent material test strips joint-detection intelligence system according to claim 3, it is characterised in that:On described Forward luminescent material test strips joint-detection intelligence system to be arranged in thermostatical storehouse, thermoregulation mechanism is provided with the thermostatical storehouse.
5. upper forwarding luminescent material test strips joint-detection intelligence system according to claim 4, it is characterised in that:On described The side of the test paper Boards wall test paper of luminescent material test strips joint-detection intelligence system is forwarded to be fixed with laser system, it is described to swash Photosystem output collection signal is single to main control unit, the main control unit output image information to memory cell and display Member.
6. upper forwarding luminescent material test strips joint-detection intelligence system according to claim 5, it is characterised in that:The master Control unit is provided with clock unit, and the main control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, waste liquid Valve, elevating mechanism, stepper motor, translation mechanism, hot gas source and lift cylinder, and receive the signal of Hall sensor.
7. based on the detection method of upper forwarding luminescent material test strips joint-detection intelligence system described in claim 6, its feature exists In:
Step 1, start for the first time, elevating mechanism and lift cylinder push, and cleaning lid blocks each test bottle, and bottle cap is blocked often One sample bottle;
Step 2, liquid feed valve, purge valve and waist valve are opened, restart pump, clean time rating, closed pump, turn off feed liquor Valve, purge valve and waist valve;
Step 3, purge valve and tapping valve are opened, restart pump, clean time rating, closed pump, turn off purge valve and discharge opeing Valve;
Step 4, liquid feed valve and tapping valve are opened, start hot gas source, dry time rating, closed hot gas source, turn off liquid feed valve And tapping valve;
Step 5, elevating mechanism and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually test paper is fixed on test paper clamping plate, quantitative test sample is injected in sample bottle;
Step 7, start for second, test bottle is moved to below test paper clamping plate;
Step 8, elevating mechanism are pushed, and test paper clamping plate is put into test bottle;
Step 9, after the delay adjustmentses time, elevating mechanism rise, laser system collection test paper image information;
Step 10, test bottle is moved to the cleaning side of covering, elevating mechanism and lift cylinder push, and cleaning lid blocks each survey Trial jar, bottle cap block each sample bottle;
Step 11, liquid feed valve, purge valve and waist valve are opened, restart pump, clean time rating, closed pump, turn off feed liquor Valve, purge valve and waist valve;
Step 12, purge valve and tapping valve are opened, restart pump, clean time rating, closed pump, turn off purge valve and discharge opeing Valve;
Step 13, liquid feed valve and tapping valve are opened, start hot gas source, dry time rating, closed hot gas source, turn off liquid feed valve And tapping valve;
Step 14, elevating mechanism and lift cylinder rise, and once test terminates.
CN201610560956.6A 2016-07-15 2016-07-15 Luminescent material test strips joint-detection intelligence system and detection method are forwarded in one kind Active CN106290827B (en)

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CN201610560956.6A CN106290827B (en) 2016-07-15 2016-07-15 Luminescent material test strips joint-detection intelligence system and detection method are forwarded in one kind

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CN106290827B true CN106290827B (en) 2018-01-30

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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4425439A1 (en) * 1994-07-19 1996-01-25 Boehringer Mannheim Gmbh Test strip evaluation device with a transport unit for test strips
CN204330764U (en) * 2015-01-05 2015-05-13 山西亚森实业股份有限公司 Urine analyzer
CN205003158U (en) * 2015-09-21 2016-01-27 马春燕 Urine verifying attachment of division of endocrinology

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