CN106290828B - A kind of smart machine and its control method for being used to detect forwarding luminescent material test strips - Google Patents

A kind of smart machine and its control method for being used to detect forwarding luminescent material test strips Download PDF

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Publication number
CN106290828B
CN106290828B CN201610561019.2A CN201610561019A CN106290828B CN 106290828 B CN106290828 B CN 106290828B CN 201610561019 A CN201610561019 A CN 201610561019A CN 106290828 B CN106290828 B CN 106290828B
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valve
bottle
test
smart machine
luminescent material
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CN106290828A (en
Inventor
陶少强
李玉峰
张士伟
张斌
王晓杨
杨彦齐
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Anhui National Science Biotechnology Co., Ltd.
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Anhui National Science Biotechnology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Include elevating mechanism, stent, cleaning lid, test paper clamping plate, shrapnel, test bottle, drain pipe, inlet tube, cleaning pipe, sample bottle and sewer pipe present invention is disclosed a kind of for detecting the smart machine of upper forwarding luminescent material test strips.The advantage of the invention is that it is easy to use, installation operation step process is required to, reduces difficulty of test, while by equipment automation control, improve the precision of test, it helps improves testing efficiency.

Description

A kind of smart machine and its control method for being used to detect forwarding luminescent material test strips
Technical field
Equipment the present invention relates to test strips made of colloidal gold (PCT) are carried out with chromatography detection.
Background technology
Although carrying out clinical detection currently with upper forwarding luminescent material test strips very to have popularized, currently with When upper forwarding luminescent material test strips carry out chromatography realization, all it is that staff is needed to be manually operated, not only increases experiment process In uncontrollability, from exist influence test accuracy hidden danger, and can only one sample of a sample detect one by one, it is difficult to It is multiple to detect simultaneously.
Invention content
The technical problems to be solved by the invention are to realize that one kind convenient, fast and accurate can carry out chromatographing intelligent inspection The equipment of survey.
To achieve these goals, the technical solution adopted by the present invention is:One kind forwards luminescent material test paper for detecting The smart machine of item, rotary shaft rack include axostylus axostyle, the bearing at axostylus axostyle both ends, two supporting rods along axostylus axostyle axial restraint, two The supporting rod is located at the not homonymy of axostylus axostyle, and the axostylus axostyle is horizontally fixed on by the bearing at both ends on the connecting rod of elevating mechanism, The axostylus axostyle peripheral hardware rack gear is fixed with stepper motor on the connecting rod, and the drive shaft of the stepper motor is equipped with and gear ring Meshed gears wherein being equidistantly fixed with row's test paper clamping plate on a supporting rod, is set on each test paper clamping plate Have at least two for clamping the shrapnels of test paper, another supporting rod, which is equidistantly fixed with one and clears, washes lid;
Row's test bottle, quantity and cleaning lid, the number of test paper clamping plate of the test bottle are equipped with below the rotary shaft rack Measure identical, and position corresponds when the fixed position of test bottle is rotated to cleaning lid or test paper clamping plate above test bottle;
Each test bottle is provided with the sample bottle that an installation site is higher than test bottle, and the sample bottle passes through feed liquor Pipe connects test bottle, and the test bottle is connected with cleaning pipe, and the cleaning pipe connects water source, the test bottle bottom connection through pump Have a drain pipe, the sample bottle bottom is connected with sewer pipe, and the drain pipe is equipped with tapping valve, the inlet tube be equipped with into Liquid valve, the cleaning pipe are equipped with purge valve, and the sewer pipe is equipped with waist valve.
The Hall sensor for measuring rotary torsion, the limit that the connecting rod and axostylus axostyle extend towards are equipped in the stepper motor Position bar.
The sample bottle be equipped with scale, and sample bottle be equipped with bottle cover bracket, the bottle cover bracket be equipped with it is each The corresponding bottle cap in sample bottle position, the bottle cover bracket are fixed on lifting cylinder, and each bottle cap lower surface is equipped with out Stomata, the venthole are connect through hose with hot gas source.
It is described to be mounted in thermostatical storehouse for detecting the smart machine of forwarding luminescent material test strips, it is set in the thermostatical storehouse There is thermoregulation mechanism.
It is described to be fixed for detecting the side of the test paper Boards wall test paper of the smart machine of forwarding luminescent material test strips There is laser system, the laser system output acquisition signal to main control unit, the main control unit output image information is extremely Storage unit and display unit.
The main control unit is equipped with clock unit, and the main control unit outputs control signals to pump, tapping valve, feed liquor Valve, purge valve, waist valve, elevating mechanism, stepper motor, hot gas source and lifting cylinder, and receive the signal of Hall sensor.
Control method based on the smart machine for being used to detect upper forwarding luminescent material test strips:
Step 1 starts for the first time, and elevating mechanism and lifting cylinder push, and cleaning lid blocks each test bottle, and bottle cap blocks up Firmly each sample bottle;
Step 2 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes and pumps, turn off into Liquid valve, purge valve and waist valve;
Step 3 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turn off purge valve with Tapping valve;
Step 4 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism and lifting cylinder rise, and wait for enabled instruction next time;
Test paper is manually fixed on test paper clamping plate by step 6, and quantitative test sample is injected in sample bottle;
Step 7 starts for second, and test paper clamping plate is moved to above test bottle;
Step 8, elevating mechanism push, and test paper clamping plate is put into test bottle;
Step 9, after the delay adjustments time, elevating mechanism rise, laser system acquisition test paper image information;
Cleaning lid is moved to above test bottle by step 10, and elevating mechanism and lifting cylinder push, and cleaning lid is blocked each A test bottle, bottle cap block each sample bottle;
Step 11 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes pump, turns off Liquid feed valve, purge valve and waist valve;
Step 12 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turn off purge valve with Tapping valve;
Step 13 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism and lifting cylinder rise, and primary test terminates.
The advantage of the invention is that it is easy to use, installation operation step process is required to, reduces difficulty of test, is led to simultaneously Equipment automation control is crossed, improves the precision of test, it helps improves testing efficiency.
Description of the drawings
The content of every width attached drawing expression in description of the invention and the label in figure are briefly described below:
Fig. 1 is the smart machine structure diagram for detecting upper forwarding luminescent material test strips;
Label in above-mentioned figure is:1st, elevating mechanism;2nd, rotary shaft rack;3rd, cleaning lid;4th, test paper clamping plate;5th, shrapnel; 6th, test bottle;7th, drain pipe;8th, inlet tube;9th, cleaning pipe;10th, sample bottle;11st, sewer pipe.
Specific embodiment
As shown in Figure 1, include elevating mechanism 1, rotary shaft rack for detecting the smart machine of upper forwarding luminescent material test strips 2nd, lid 3, test paper clamping plate 4, shrapnel 5, test bottle 6, drain pipe 7, inlet tube 8, cleaning pipe 9, sample bottle 10 and sewer pipe 11 are cleaned. Smart machine for detecting upper forwarding luminescent material test strips is mounted in thermostatical storehouse, and thermoregulation mechanism is equipped in thermostatical storehouse, Can further control make experimental enviroment by the temperature in regulating thermostatic storehouse in this way, improve experiment reliability and can Control property.
Equipment is equipped with rotary shaft rack 2, and rotary shaft rack 2 includes axostylus axostyle, the bearing at axostylus axostyle both ends, two along axostylus axostyle axial restraint Root supporting rod, rotary shaft rack 2 is horizontal fixed, and rotary shaft rack 2 is fixed on by the bearing at both ends on the connecting rod of elevating mechanism, in this way Rotary shaft rack can be along the link rotatable of elevating mechanism 1, axostylus axostyle peripheral hardware rack gear, and stepper motor, stepping are fixed on connecting rod The drive shaft of motor be equipped with gear ring meshed gears, in this way can pass through stepper motor adjust rotary shaft rack 2 angle of rotation Degree.The Hall sensor for measuring rotary torsion is equipped in stepper motor, connecting rod and axostylus axostyle are equipped with the gag lever post extended towards, limit Rotary shaft rack 2 processed can only rotate restriction angle, recycle Hall sensor can be to avoid overexercise, the two cooperation can be accurate Control rotary shaft rack 2 rotation position.Further, it is also possible to fix lock-up cylinder on connecting rod, the locking hole on axostylus axostyle works as rotation After going to setting position, locking axostylus axostyle in locking hole can be stretched by lock-up cylinder, it is ensured that axostylus axostyle will not be sent out when pushing work Raw rotation.
Wherein supporting rod lower surface is equipped with equidistant fixed test paper clamping plate 4 vertically, under another supporting rod Surface is equipped with equidistantly fixed cleaning lid 3, each test paper clamping plate 4 and is equipped at least two for clamping test paper vertically Shrapnel 5.
The lower section of supporting rod is equipped with row's test bottle 6, test bottle 6 with clean lid 3, test paper clamping plate 4 be it is matching used, because The quantity of this test bottle 6 is identical with the quantity of test paper clamping plate 4 with cleaning lid 3 and the quantity of test bottle 6, is supported every time After the adjustment of bar position, position is mutual when the fixed position of test bottle 6 moves to 6 top of test bottle with cleaning lid 3 or test paper clamping plate 4 Corresponding, i.e., each cleaning lid 3 can fill in the bottleneck to a test bottle 6, and each test paper clamping plate 4 can be put into a test bottle In 6 bottle.
Each test bottle 6 is provided with the sample bottle 10 that an installation site is higher than test bottle 6, i.e. liquid in sample bottle 10 Body can be by the way that in gravity flowing to test bottle 6, sample bottle 10 connects test bottle 6 by inlet tube 8, and test bottle 6 is connected with clearly Pipe 9 is washed, cleaning pipe 9 connects water source through pump, and 6 bottom of test bottle is connected with drain pipe 7, and 10 bottom of sample bottle is connected with sewer pipe 11, drain pipe 7 is equipped with tapping valve, and inlet tube 8 is equipped with liquid feed valve, and cleaning pipe 9 is equipped with purge valve, and sewer pipe 11 is equipped with Waist valve.
Sample bottle 10 is equipped with scale, and convenient for users to accurately importing measurement liquid, and sample bottle 10 is equipped with bottle cap Stent, bottle cover bracket are equipped with bottle cap corresponding with each 10 position of sample bottle, i.e. the quantity of bottle cap and sample bottle 10, position is equal Identical and corresponding, bottle cover bracket is fixed on lifting cylinder, and each bottle cap lower surface is equipped with venthole, venthole through hose with Hot gas source connects, and can dry ponding by hot gas source, avoid influencing result of the test.Sample bottle 10 and test bottle 6 use Transparent vial body facilitates observation.
In order to improve the reliability of capping, bottle cap and cleaning 3 upper surface of lid pass through spring and lifting cylinder, elevating mechanism 1 Connection, lower surface are equipped with rubber pad, so that it is guaranteed that leakproofness during cleaning.
In order to coordinate whole equipment work, equipment is equipped with main control unit, and main control unit is equipped with clock unit, main Control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, waist valve, elevating mechanism 1, stepper motor, hot gas Source and lifting cylinder, and the signal of Hall sensor is received, for detecting the examination of the smart machine of upper forwarding luminescent material test strips The side that paper clip-board 4 fixes test paper is fixed with laser system, and laser system includes laser emitter and receives the reception of reflected light Device emits laser to each test paper, then received by receiver by laser emitter, can obtain the test result of needs, swash For photosystem output acquisition signal to main control unit, main control unit exports image information to storage unit and display unit, this Sample can accurately record the test paper state after test.
Control method based on the above-mentioned smart machine for being used to detect upper forwarding luminescent material test strips:
Step 1 starts for the first time, and elevating mechanism 1 and lifting cylinder push, and cleaning lid 3 blocks each test bottle 6, bottle Lid blocks each sample bottle 10;(being that cleaning lid 3 is located at 6 top of test bottle after every time);
Step 2 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes and pumps, turn off into Liquid valve, purge valve and waist valve;
Step 3 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turn off purge valve with Tapping valve;
So as to clean sample bottle 10 and test bottle 6, avoid interfering;
Step 4 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism 1 and lifting cylinder rise, and wait for enabled instruction next time;
Test paper is manually fixed on test paper clamping plate 4 by step 6, the injection quantitative test sample in sample bottle 10;
Step 7 starts for second, and test paper clamping plate 4 is moved to 6 top of test bottle;
Step 8, elevating mechanism 1 push, and test paper clamping plate 4 is put into test bottle 6;
Step 9, after the delay adjustments time, elevating mechanism 1 rises, laser system acquisition test paper image information;
Cleaning lid 3 is moved to 6 top of test bottle by step 10, and elevating mechanism 1 and lifting cylinder push, and cleaning lid 3 is blocked Each test bottle 6, bottle cap block each sample bottle 10;
Step 11 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes pump, turns off Liquid feed valve, purge valve and waist valve;
Step 12 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turn off purge valve with Tapping valve;
So as to be cleaned to sample bottle 10 and test bottle 6, avoid interfering, avoid interfering to testing next time;
Step 13 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism 1 and lifting cylinder rise, and primary test terminates.
All operations of intelligent automaticization, specification testing process, accurate test result, and facilitate staff It uses, multigroup sample under similary environment can be tested simultaneously, facilitate comparison and record.
The present invention is exemplarily described above in conjunction with attached drawing, it is clear that present invention specific implementation is not by aforesaid way Limitation, as long as employ the inventive concept and technical scheme of the present invention progress various unsubstantialities improvement or without changing Other occasions are directly applied to by the design of the present invention and technical solution, within protection scope of the present invention.

Claims (7)

1. a kind of smart machine for being used to detect forwarding luminescent material test strips, it is characterised in that:The smart machine includes rising Descending mechanism, rotary shaft rack, cleaning lid, test paper clamping plate, shrapnel, test bottle, drain pipe, inlet tube, cleaning pipe, sample bottle and waste liquid Pipe;
The rotary shaft rack includes axostylus axostyle, the bearing at axostylus axostyle both ends, two supporting rods along axostylus axostyle axial restraint, two branch Strut is located at the not homonymy of axostylus axostyle, and the axostylus axostyle is horizontally fixed on by the bearing at both ends on the connecting rod of elevating mechanism, the axis Bar peripheral hardware rack gear, stepper motor is fixed on the connecting rod, and the drive shaft of the stepper motor is equipped with what is engaged with gear ring Gear, wherein being equidistantly fixed with row's test paper clamping plate on a supporting rod, each test paper clamping plate is equipped at least Two for clamping the shrapnels of test paper, another supporting rod, which is equidistantly fixed with one and clears, washes lid;
Row's test bottle, the quantity of the test bottle and the quantity phase of cleaning lid, test paper clamping plate are equipped with below the rotary shaft rack Together, position corresponds when and the fixed position of test bottle is rotated to above test bottle with cleaning lid or test paper clamping plate;
Each test bottle is provided with the sample bottle that an installation site is higher than test bottle, and the sample bottle is connected by inlet tube Logical test bottle, the test bottle are connected with cleaning pipe, and the cleaning pipe connects water source through pump, and the test bottle bottom is connected with row Liquid pipe, the sample bottle bottom are connected with sewer pipe, and the drain pipe is equipped with tapping valve, and the inlet tube is equipped with feed liquor Valve, the cleaning pipe are equipped with purge valve, and the sewer pipe is equipped with waist valve.
2. the smart machine according to claim 1 for being used to detect forwarding luminescent material test strips, it is characterised in that:It is described The Hall sensor for measuring rotary torsion is equipped in stepper motor, gag lever post, the connecting rod are equipped on the connecting rod and axostylus axostyle It is extended towards with the gag lever post on axostylus axostyle.
3. the smart machine according to claim 2 for being used to detect forwarding luminescent material test strips, it is characterised in that:It is described Sample bottle is equipped with scale, and sample bottle is equipped with bottle cover bracket, and the bottle cover bracket is equipped with and each sample bottle position pair The bottle cap answered, the bottle cover bracket are fixed on lifting cylinder, and each bottle cap lower surface is equipped with venthole, the outlet Hole is connect through hose with hot gas source.
4. the smart machine according to claim 3 for being used to detect forwarding luminescent material test strips, it is characterised in that:It is described Smart machine for detecting upper forwarding luminescent material test strips is mounted in thermostatical storehouse, and temperature adjuster is equipped in the thermostatical storehouse Structure.
5. the smart machine according to claim 4 for being used to detect forwarding luminescent material test strips, it is characterised in that:It is described Side for detecting the test paper Boards wall test paper of the smart machine of upper forwarding luminescent material test strips is fixed with laser system, institute Laser system output acquisition signal is stated to main control unit, the main control unit exports image information to storage unit and display Unit.
6. the smart machine according to claim 5 for being used to detect forwarding luminescent material test strips, it is characterised in that:It is described Main control unit is equipped with clock unit, and the main control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, gives up Liquid valve, elevating mechanism, stepper motor, hot gas source and lifting cylinder, and receive the signal of Hall sensor.
7. based on the control method that the smart machine for detecting upper forwarding luminescent material test strips is used for described in claim 6, feature It is:
Step 1 starts for the first time, and elevating mechanism and lifting cylinder push, and cleaning lid blocks each test bottle, and bottle cap is blocked often One sample bottle;
Step 2 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes pump, turns off feed liquor Valve, purge valve and waist valve;
Step 3 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turns off purge valve and drain Valve;
Step 4 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turns off liquid feed valve And tapping valve;
Step 5, elevating mechanism and lifting cylinder rise, and wait for enabled instruction next time;
Test paper is manually fixed on test paper clamping plate by step 6, and quantitative test sample is injected in sample bottle;
Step 7 starts for second, and test paper clamping plate is moved to above test bottle;
Step 8, elevating mechanism push, and test paper clamping plate is put into test bottle;
Step 9, after the delay adjustments time, elevating mechanism rise, laser system acquisition test paper image information;
Cleaning lid is moved to above test bottle by step 10, and elevating mechanism and lifting cylinder push, and cleaning lid blocks each survey Trial jar, bottle cap block each sample bottle;
Step 11 opens liquid feed valve, purge valve and waist valve, restarts pump, cleans time rating, closes pump, turns off feed liquor Valve, purge valve and waist valve;
Step 12 opens purge valve and tapping valve, restarts pump, cleans time rating, closes pump, turns off purge valve and drain Valve;
Step 13 opens liquid feed valve and tapping valve, starts hot gas source, dries time rating, closes hot gas source, turns off liquid feed valve And tapping valve;
Step 14, elevating mechanism and lifting cylinder rise, and primary test terminates.
CN201610561019.2A 2016-07-15 2016-07-15 A kind of smart machine and its control method for being used to detect forwarding luminescent material test strips Active CN106290828B (en)

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CN1690711B (en) * 2004-04-23 2010-04-14 中国人民解放军军事医学科学院微生物流行病研究所 Immune chromatographic test paper bar based on up conversion luminescence technology
US7241417B2 (en) * 2004-07-29 2007-07-10 Savyon Diagnostics Ltd. Assay device
CN2739639Y (en) * 2004-11-17 2005-11-09 泰博科技股份有限公司 Intelligent biosensor device
CN103149353B (en) * 2013-02-05 2015-05-13 中国科学院上海光学精密机械研究所 Quantitative detection system and detection method for multi-channel test paper disc
CN203365444U (en) * 2013-05-22 2013-12-25 姜志凌 Automatic test strip outputting detector
CN203376262U (en) * 2013-07-03 2014-01-01 深圳市爱德康科技有限公司 Monitor with blood test and urine test components
CN104198687A (en) * 2014-09-04 2014-12-10 崔艳香 Clinical laboratory saliva detector

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