CN106290828A - A kind of smart machine for detecting upper forwarding luminescent material test strips and control method thereof - Google Patents

A kind of smart machine for detecting upper forwarding luminescent material test strips and control method thereof Download PDF

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Publication number
CN106290828A
CN106290828A CN201610561019.2A CN201610561019A CN106290828A CN 106290828 A CN106290828 A CN 106290828A CN 201610561019 A CN201610561019 A CN 201610561019A CN 106290828 A CN106290828 A CN 106290828A
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valve
bottle
test
reagent paper
luminescent material
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CN106290828B (en
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陶少强
李玉峰
张士伟
张斌
王晓杨
杨彦齐
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Anhui National Science Biotechnology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Present invention is disclosed a kind of smart machine for detecting upper forwarding luminescent material test strips and include elevating mechanism, support, cleaning lid, reagent paper clamping plate, shell fragment, test bottle, discharging tube, feed tube, cleaning pipe, sample bottle and sewer pipe.It is an advantage of the current invention that easy to use, be required to that operating procedure is installed and process, reduce difficulty of test, simultaneously by equipment automation control, improve the precision of test, it helps improve testing efficiency.

Description

A kind of smart machine for detecting upper forwarding luminescent material test strips and control method thereof
Technical field
The test strips (PCT) that the present invention relates to make gold colloidal carries out the equipment of chromatography detection.
Background technology
Although carrying out Clinical detection the most very universal currently with upper forwarding luminescent material test strips, but currently with Upper forwarding luminescent material test strips carries out chromatography when realizing, and is all to need staff's manual operation, not only increases process of the test In uncontrollability, affect the hidden danger of test accuracy from existing, and can only detect one by one by one sample of a sample, it is difficult to Multiple detect simultaneously.
Summary of the invention
The technical problem to be solved is to realize one can convenient, fast and accurate carry out chromatographing intelligence inspection The equipment surveyed.
To achieve these goals, the technical solution used in the present invention is: one is used for detecting forwarding luminescent material reagent paper The smart machine of bar, rotary shaft rack includes axostylus axostyle, the bearing at axostylus axostyle two ends, two support bars along axostylus axostyle axial restraint, two Described support bar is positioned at the not homonymy of axostylus axostyle, and described axostylus axostyle is horizontally fixed on the connecting rod of elevating mechanism by the bearing at two ends, Described axostylus axostyle is externally provided with gear ring, and described connecting rod is fixed with motor, and the drive shaft of described motor is provided with and gear ring Meshed gears, is wherein equidistantly fixed with row's reagent paper clamping plate, each described reagent paper clamping plate sets on a described support bar Having at least two for clamping the shell fragment of reagent paper, support bar described in another root is equidistantly fixed with one and clears and wash lid;
Row's test bottle, the quantity of described test bottle and cleaning lid, the number of reagent paper clamping plate it is provided with below described rotary shaft rack Measure identical, and when the fixed position of test bottle rotates to above test bottle with cleaning lid or reagent paper clamping plate, position is the most corresponding;
Each described test bottle is provided with the installation site sample bottle higher than test bottle, and described sample bottle passes through feed liquor Pipe connection test bottle, described test bottle connects cleaning pipe, and described cleaning pipe connects water source through pump, connects bottom described test bottle Have discharging tube, bottom described sample bottle connect have sewer pipe, described discharging tube to be provided with tapping valve, described feed tube be provided with into Liquid valve, described cleaning pipe is provided with purge valve, and described sewer pipe is provided with waist valve.
The Hall element measuring rotary torsion, the limit that described connecting rod and axostylus axostyle extend towards it is provided with in described motor Position bar.
Described sample bottle is provided with scale, and sample bottle is provided with bottle cover bracket, and described bottle cover bracket is provided with each The bottle cap that sample bottle position is corresponding, described bottle cover bracket is fixed on lift cylinder, and each described bottle cap lower surface is equipped with out Pore, described venthole is connected with hot gas source through flexible pipe.
The described smart machine for detecting upper forwarding luminescent material test strips is arranged in thermostatical storehouse, sets in described thermostatical storehouse There is thermoregulation mechanism.
The described side for the reagent paper Boards wall reagent paper of the smart machine detecting upper forwarding luminescent material test strips is fixed Having laser system, described laser system output collection signal is to main control unit, and described main control unit output image information is extremely Memory element and display unit.
Described main control unit is provided with clock unit, and described main control unit outputs control signals to pump, tapping valve, feed liquor Valve, purge valve, waist valve, elevating mechanism, motor, hot gas source and lift cylinder, and receive the signal of Hall element.
Control method based on the described smart machine for detecting upper forwarding luminescent material test strips:
Step 1, for the first time startup, press under elevating mechanism and lift cylinder, cleans lid and blocks each test bottle, and bottle cap blocks up Live each sample bottle;
Step 2, open liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off into Liquid valve, purge valve and waist valve;
Step 3, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Step 4, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually reagent paper is fixed on reagent paper clamping plate, in sample bottle, injects quantitative test sample;
Step 7, second time start, and are moved to above test bottle by reagent paper clamping plate;
Pressing under step 8, elevating mechanism, reagent paper clamping plate are put in test bottle;
Step 9, after the delay adjustments time, elevating mechanism rise, laser system gather reagent paper image information;
Step 10, cleaning lid is moved to above test bottle, press under elevating mechanism and lift cylinder, clean lid and block each Individual test bottle, bottle cap blocks each sample bottle;
Step 11, unlatching liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off Liquid feed valve, purge valve and waist valve;
Step 12, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Step 13, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism and lift cylinder rise, and once test terminates.
It is an advantage of the current invention that easy to use, be required to that operating procedure is installed and process, reduce difficulty of test, lead to simultaneously Cross equipment automation control, improve the precision of test, it helps improve testing efficiency.
Accompanying drawing explanation
Labelling in the content expressed every width accompanying drawing in description of the invention below and figure is briefly described:
Fig. 1 is the smart machine structural representation for detecting upper forwarding luminescent material test strips;
Labelling in above-mentioned figure is: 1, elevating mechanism;2, rotary shaft rack;3, lid is cleaned;4, reagent paper clamping plate;5, shell fragment; 6, test bottle;7, discharging tube;8, feed tube;9, pipe is cleaned;10, sample bottle;11, sewer pipe.
Detailed description of the invention
As it is shown in figure 1, include elevating mechanism 1, rotary shaft rack for detecting the smart machine of forwarding luminescent material test strips 2, clean lid 3, reagent paper clamping plate 4, shell fragment 5, test bottle 6, discharging tube 7, feed tube 8, clean pipe 9, sample bottle 10 and sewer pipe 11. Smart machine for detecting upper forwarding luminescent material test strips is arranged in thermostatical storehouse, is provided with thermoregulation mechanism in thermostatical storehouse, So can make experimental enviroment further to control by the temperature in regulating thermostatic storehouse, improve test reliability and can Control property.
Equipment is provided with rotary shaft rack 2, rotary shaft rack 2 include axostylus axostyle, the bearing at axostylus axostyle two ends, along the two of axostylus axostyle axial restraint Root support bar, rotary shaft rack 2 level fixes, and rotary shaft rack 2 is fixed on the connecting rod of elevating mechanism by the bearing at two ends, so Rotary shaft rack can be along the link rotatable of elevating mechanism 1, and axostylus axostyle is externally provided with gear ring, and connecting rod is fixed with motor, stepping The drive shaft of motor is provided with and gear ring meshed gears, so can be by the angle of rotation of motor regulation rotary shaft rack 2 Degree.Being provided with the Hall element measuring rotary torsion in motor, connecting rod and axostylus axostyle are provided with the gag lever post extended towards, limit Rotary shaft rack 2 processed can only rotate restriction angle, and recycling Hall element can avoid hyperkinesia, and both cooperations can be accurate Control rotary shaft rack 2 position of rotation.Further, it is also possible to fix lock-up cylinder on connecting rod, locking hole on axostylus axostyle, work as rotation After forwarding setting position to, locking axostylus axostyle in locking hole can be stretched into by lock-up cylinder, it is ensured that during pressure work, axostylus axostyle will not be sent out down Raw rotation.
Wherein a support bar lower surface is vertically provided with the most fixing reagent paper clamping plate 4, under support bar described in another root Surface is vertically provided with the most fixing cleaning lid 3, and each described reagent paper clamping plate 4 are provided with at least two for clamping reagent paper Shell fragment 5.
The lower section of support bar is provided with row's test bottle 6, and test bottle 6 is matching used with cleaning lid 3, reagent paper clamping plate 4, because of The quantity of this test bottle 6 with clean lid 3, and the quantity of test bottle 6 is all identical with the quantity of reagent paper clamping plate 4, supports every time After bar position adjustment, when the fixed position of test bottle 6 moves to above test bottle 6 with cleaning lid 3 or reagent paper clamping plate 4, position is mutual Correspondence, the most each cleaning covers 3 can fill in the bottleneck to a test bottle 6, and each reagent paper clamping plate 4 can put into a test bottle In the bottle of 6.
Each test bottle 6 is provided with the installation site sample bottle 10 higher than test bottle 6, i.e. liquid in sample bottle 10 Can be flow in test bottle 6 by gravity, sample bottle 10 connects test bottle 6 by feed tube 8, and test bottle 6 connects cleaning Pipe 9, cleans pipe 9 and connects water source through pump, and connecting bottom test bottle 6 has discharging tube 7, and connecting bottom sample bottle 10 has sewer pipe 11, Discharging tube 7 is provided with tapping valve, and feed tube 8 is provided with liquid feed valve, cleans pipe 9 and is provided with purge valve, and sewer pipe 11 is provided with useless Liquid valve.
Sample bottle 10 is provided with scale, facilitates user to import measurement liquid accurately, and sample bottle 10 is provided with bottle cap Support, it is equal that bottle cover bracket is provided with the bottle cap corresponding with each sample bottle 10 position, i.e. bottle cap and the quantity of sample bottle 10, position Identical and corresponding, bottle cover bracket is fixed on lift cylinder, and each bottle cap lower surface is equipped with venthole, venthole through flexible pipe with Hot gas source connects, and can dry hydrops by hot gas source, it is to avoid have influence on result of the test.Sample bottle 10 and test bottle 6 all use Transparent vial body, convenient observation.
In order to improve the reliability of capping, bottle cap and cleaning lid 3 upper surfaces are by spring and lift cylinder, elevating mechanism 1 Connecting, lower surface is provided with rubber blanket, so that it is guaranteed that sealing when cleaning.
In order to coordinate the work of whole equipment, equipment is provided with main control unit, and main control unit is provided with clock unit, main Control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, waist valve, elevating mechanism 1, motor, steam Source and lift cylinder, and receive the signal of Hall element, for detecting the examination of the smart machine of forwarding luminescent material test strips Paper clip-board 4 is fixed the side of reagent paper and is fixed with laser system, and laser system includes generating laser and receives the reception of reflection light Device, launches laser by generating laser to each reagent paper, then is received by receptor, it is possible to obtain the test result needed, and swashs Photosystem output gathers signal to main control unit, main control unit output image information to memory element and display unit, this Sample can record the reagent paper state after test accurately.
Control method based on the above-mentioned smart machine for detecting upper forwarding luminescent material test strips:
Step 1, for the first time startup, press under elevating mechanism 1 and lift cylinder, cleans lid 3 and blocks each test bottle 6, bottle Lid blocks each sample bottle 10;(after terminating, being all to clean lid 3 to be positioned at above test bottle 6) every time;
Step 2, open liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off into Liquid valve, purge valve and waist valve;
Step 3, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Thus sample bottle 10 and test bottle 6 are carried out, it is to avoid interference;
Step 4, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 5, elevating mechanism 1 and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually reagent paper is fixed on reagent paper clamping plate 4, in sample bottle 10, injects quantitative test sample;
Step 7, second time start, and are moved to above test bottle 6 by reagent paper clamping plate 4;
Step 8, elevating mechanism are pressed for 1 time, and reagent paper clamping plate 4 are put in test bottle 6;
Step 9, after the delay adjustments time, elevating mechanism 1 rises, laser system gather reagent paper image information;
Step 10,3 move to, above test bottle 6, press under elevating mechanism 1 and lift cylinder by cleaning lid, clean lid 3 and block Each test bottle 6, bottle cap blocks each sample bottle 10;
Step 11, unlatching liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off Liquid feed valve, purge valve and waist valve;
Step 12, open purge valve and tapping valve, restart pump, clean time rating, close pump, turn off purge valve and Tapping valve;
Thus sample bottle 10 and test bottle 6 are carried out, it is to avoid interference, it is to avoid test next time is interfered;
Step 13, open liquid feed valve and tapping valve, start hot gas source, dry time rating, close hot gas source, turn off into Liquid valve and tapping valve;
Step 14, elevating mechanism 1 and lift cylinder rise, and once test terminates.
The operation of whole intelligent automaticization, specification testing process, accurate test result, and facilitate staff Use, many group samples can be tested in the environment of same simultaneously, facilitate comparison and record.
Above in conjunction with accompanying drawing, the present invention is exemplarily described, it is clear that the present invention implements not by aforesaid way Restriction, as long as have employed the method design of the present invention and the improvement of various unsubstantialities that technical scheme is carried out, or without changing Enter and design and the technical scheme of the present invention are directly applied to other occasion, all within protection scope of the present invention.

Claims (7)

1. the smart machine being used for detecting forwarding luminescent material test strips, it is characterised in that:
Rotary shaft rack includes axostylus axostyle, the bearing at axostylus axostyle two ends, two support bars along axostylus axostyle axial restraint, two described support bars Being positioned at the not homonymy of axostylus axostyle, described axostylus axostyle is horizontally fixed on the connecting rod of elevating mechanism by the bearing at two ends, outside described axostylus axostyle Being provided with gear ring, described connecting rod is fixed with motor, the drive shaft of described motor is provided with and gear ring meshed gears, Wherein equidistantly being fixed with row's reagent paper clamping plate on a described support bar, each described reagent paper clamping plate are provided with at least two and use In the shell fragment of clamping reagent paper, support bar described in another root is equidistantly fixed with one and clears and wash lid;
Row's test bottle, the quantity of described test bottle and cleaning lid, the quantity phase of reagent paper clamping plate it is provided with below described rotary shaft rack With, and when the fixed position of test bottle rotates to above test bottle with cleaning lid or reagent paper clamping plate, position is the most corresponding;
Each described test bottle is provided with the installation site sample bottle higher than test bottle, and described sample bottle is by feed tube even Logical test bottle, described test bottle connects cleaning pipe, and described cleaning pipe connects water source through pump, and connecting bottom described test bottle has row Liquid pipe, connects bottom described sample bottle and has sewer pipe, described discharging tube to be provided with tapping valve, and described feed tube is provided with feed liquor Valve, described cleaning pipe is provided with purge valve, and described sewer pipe is provided with waist valve.
Smart machine for detecting upper forwarding luminescent material test strips the most according to claim 1, it is characterised in that: described The Hall element measuring rotary torsion, the gag lever post that described connecting rod and axostylus axostyle extend towards it is provided with in motor.
Smart machine for detecting upper forwarding luminescent material test strips the most according to claim 1 and 2, it is characterised in that: Described sample bottle is provided with scale, and sample bottle is provided with bottle cover bracket, and described bottle cover bracket is provided with and each sample bottle position Putting the bottle cap of correspondence, described bottle cover bracket is fixed on lift cylinder, and each described bottle cap lower surface is equipped with venthole, described Venthole is connected with hot gas source through flexible pipe.
Smart machine for detecting upper forwarding luminescent material test strips the most according to claim 3, it is characterised in that: described Smart machine for detecting upper forwarding luminescent material test strips is arranged in thermostatical storehouse, is provided with temperature adjuster in described thermostatical storehouse Structure.
Smart machine for detecting upper forwarding luminescent material test strips the most according to claim 4, it is characterised in that: described It is fixed with laser system, institute for detecting the side of the reagent paper Boards wall reagent paper of the smart machine of upper forwarding luminescent material test strips State laser system output gather signal to main control unit, described main control unit output image information is to memory element and display Unit.
Smart machine for detecting upper forwarding luminescent material test strips the most according to claim 5, it is characterised in that: described Main control unit is provided with clock unit, and described main control unit outputs control signals to pump, tapping valve, liquid feed valve, purge valve, gives up Liquid valve, elevating mechanism, motor, hot gas source and lift cylinder, and receive the signal of Hall element.
7., based on being used for detecting the control method of the smart machine of upper forwarding luminescent material test strips described in claim 1-6, it is special Levy and be:
Step 1, for the first time startup, press under elevating mechanism and lift cylinder, cleans lid and blocks each test bottle, and bottle cap is blocked often One sample bottle;
Step 2, unlatching liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off feed liquor Valve, purge valve and waist valve;
Step 3, unlatching purge valve and tapping valve, restart pump, cleans time rating, closes pump, turns off purge valve and discharge opeing Valve;
Step 4, unlatching liquid feed valve and tapping valve, start hot gas source, dries time rating, closes hot gas source, turns off liquid feed valve And tapping valve;
Step 5, elevating mechanism and lift cylinder rise, and wait enabled instruction next time;
Step 6, manually reagent paper is fixed on reagent paper clamping plate, in sample bottle, injects quantitative test sample;
Step 7, second time start, and are moved to above test bottle by reagent paper clamping plate;
Pressing under step 8, elevating mechanism, reagent paper clamping plate are put in test bottle;
Step 9, after the delay adjustments time, elevating mechanism rise, laser system gather reagent paper image information;
Step 10, cleaning lid is moved to above test bottle, press under elevating mechanism and lift cylinder, clean lid and block each and survey Trial jar, bottle cap blocks each sample bottle;
Step 11, unlatching liquid feed valve, purge valve and waist valve, restart pump, clean time rating, close pump, turn off feed liquor Valve, purge valve and waist valve;
Step 12, unlatching purge valve and tapping valve, restart pump, cleans time rating, closes pump, turns off purge valve and discharge opeing Valve;
Step 13, unlatching liquid feed valve and tapping valve, start hot gas source, dries time rating, closes hot gas source, turns off liquid feed valve And tapping valve;
Step 14, elevating mechanism and lift cylinder rise, and once test terminates.
CN201610561019.2A 2016-07-15 2016-07-15 A kind of smart machine and its control method for being used to detect forwarding luminescent material test strips Active CN106290828B (en)

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