CN106266962A - A kind of medicament composing prescription for the nursing of puerpera's postpartum depression and preparation method - Google Patents

A kind of medicament composing prescription for the nursing of puerpera's postpartum depression and preparation method Download PDF

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CN106266962A
CN106266962A CN201610791359.4A CN201610791359A CN106266962A CN 106266962 A CN106266962 A CN 106266962A CN 201610791359 A CN201610791359 A CN 201610791359A CN 106266962 A CN106266962 A CN 106266962A
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parts
radix
fructus
puerpera
flos
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牟美玲
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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Abstract

The invention discloses a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including the raw material of following weight portion: Fructus Jujubae 10 20 parts, Fructus Momordicae 20 30 parts, Herba Lycopi 5 15 parts, Lignum Aquilariae Resinatum 8 20 parts, Herba Cistanches 10 20 parts, Radix Platycodonis 10 20 parts, Radix Angelicae Sinensis 5 15 parts, Rhizoma Acori Graminei 15 25 parts, Radix Ophiopogonis 15 25 parts, Rhizoma Chuanxiong 10 30 parts, 10 30 parts of Poria, Semen Ziziphi Spinosae 15 25 parts, Fructus Schisandrae Chinensis 10 30 parts, Radix Salviae Miltiorrhizae 10 30 parts, Radix Curcumae 10 30 parts, Pericarpium Citri Reticulatae 15 25 parts, Fructus Aurantii 10 20 parts, Radix Polygalae 5 15 parts, Flos Albiziae 7 17 parts, Flos Rosae Rugosae 4 14 parts.Its preparation method comprises the following steps: (1) weighs, mixes；(2) pulverizing, extract, centrifugation, clean immersion is condensed into thick paste；(3) thick paste vacuum drying, dried cream powder is broken, adds proper auxiliary materials, makes corresponding dosage form.The present invention has effect of dispersing the stagnated liver-QI for regulating the stomach, clearing heat and relieving fidgetness, regulating QI to remove the stagnation, nourishing blood to tranquillize the mind, can effectively treat puerpera's postpartum depression.Preparation method is simple, and good absorbing effect, and low cost are without any side effects.

Description

A kind of medicament composing prescription for the nursing of puerpera's postpartum depression and preparation method
Technical field
The present invention relates to a kind of Chinese medicine composition, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression and Preparation method.
Background technology
Postpartum depression is that puerpera is with the low mood disorders as principal character of mental state.Primary disease sickness rate is higher, and along with Socioeconomic development presents the trend persistently raised.Postpartum depression not only has a strong impact on the physical and mental health of puerpera, and impact The development of the emotion of baby, intelligence and behavior and family harmony.Postpartum depression can develop into major depression, occur hallucination, from Residual, commit suiside or infanticide, it is the most lifelong to the several years that the course of disease can delay the several months.Therefore, the patient of postpartum depression needs positive facing Bed is intervened, to alleviate or to eliminate postpartum depression symptom as early as possible and to reduce the risk of recurrence.Etiology to postpartum depression at present Research is not yet clear and definite, there is no unified therapeutic scheme the most clinically.
Summary of the invention
It is an object of the invention to provide a kind of medicament composing prescription for the nursing of puerpera's postpartum depression and preparation method, with The problem solving to propose in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme:
A kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including the raw material of following weight portion: Fructus Jujubae 10-20 Part, Fructus Momordicae 20-30 part, Herba Lycopi's 5-15 part, Lignum Aquilariae Resinatum 8-20 part, Herba Cistanches 10-20 part, Radix Platycodonis 10-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Acori Graminei 15-25 part, 15-25 part Radix Ophiopogonis, Rhizoma Chuanxiong 10-30 part, Poria 10-30 part, Semen Ziziphi Spinosae 15-25 part, Fructus Schisandrae Chinensis 10-30 Part, Radix Salviae Miltiorrhizae 10-30 part, Radix Curcumae 10-30 part, Pericarpium Citri Reticulatae 15-25 part, Fructus Aurantii 10-20 part, Radix Polygalae 5-15 part, Radix Glycyrrhizae 10-20 part, thin Lotus 10-20 part, Flos Chrysanthemi 10-20 part, Flos Albiziae 7-17 part, Flos Rosae Rugosae 4-14 part.
As the further scheme of the present invention: include the raw material of following weight portion: Fructus Jujubae 12.5-17.5 part, Fructus Momordicae 22.5-27.5 part, Herba Lycopi's 7.5-12.5 part, Lignum Aquilariae Resinatum 11-17 part, Herba Cistanches 12.5-17.5 part, Radix Platycodonis 12.5-17.5 part, Radix Angelicae Sinensis 7.5-12.5 part, Rhizoma Acori Graminei 17.5-22.5 part, 17.5-22.5 part Radix Ophiopogonis, Rhizoma Chuanxiong 15-25 part, Poria 15-25 part, Semen Ziziphi Spinosae 17.5-22.5 part, Fructus Schisandrae Chinensis 15-25 part, Radix Salviae Miltiorrhizae 15-25 part, Radix Curcumae 15-25 part, Pericarpium Citri Reticulatae 17.5-22.5 part, Fructus Aurantii 12.5- 17.5 parts, Radix Polygalae 7.5-12.5 part, Radix Glycyrrhizae 12.5-17.5 part, Herba Menthae 12.5-17.5 part, Flos Chrysanthemi 12.5-17.5 part, Flos Albiziae 9-15 part, Flos Rosae Rugosae 6-12 part.
As the present invention further scheme: include the raw material of following weight portion: Fructus Jujubae 15 parts, Fructus Momordicae 25 parts, pool 10 parts of orchid, Lignum Aquilariae Resinatum 14 parts, Herba Cistanches 15 parts, Radix Platycodonis 15 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Acori Graminei 20 parts, Radix Ophiopogonis 20 parts, Rhizoma Chuanxiong 20 parts, Fu Siberian cocklebur 20 parts, Semen Ziziphi Spinosae 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Curcumae 20 parts, Pericarpium Citri Reticulatae 20 parts, Fructus Aurantii 15 parts, Radix Polygalae 10 parts, sweet Grass 15 parts, Herba Menthae 15 parts, Flos Chrysanthemi 15 parts, Flos Albiziae 12 parts, Flos Rosae Rugosae 9 parts.
As the present invention further scheme: the preparation of the described medicament composing prescription for the nursing of puerpera's postpartum depression Method, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 10-20 mesh coarse granule, adds 50-70% ethanol by 5-7 times amount, use microwave Continuous 50-70 DEG C of extracting process extracts three times, and extract is centrifuged separating, and it is 1.20-that clean immersion is concentrated into relative density 1.30 thick paste；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds proper auxiliary materials, makes corresponding dosage form.
As the present invention further scheme: in step (3), adjuvant adds appropriate amylum pregelatinisatum and carboxymethyl cellulose Sodium, mixed 80-120 mesh sieve, adds suitable quantity of water and pelletizes, 60 DEG C of drying under reduced pressure, granulate, subpackage.
Fructus Jujubae: warm in nature, sweet in the mouth.Return spleen channel, stomach warp, heart channel.Effect and effect: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Belong to qi-restoratives medicine The Qi-tonifying drug of subordinate's classification.With controlling insufficiency of the spleen lack of appetite, qi-blood-body fluid is not enough, the weak just pool, married woman are dirty dry.There is physical strength reinforcing, resist Fatigue, tranquillizing and allaying excitement, protect the liver, increase leukocyte CAMP, strengthen immunity and the function such as antiallergic action.
Herba Lycopi: slightly warm in nature, bitter in the mouth.Return Liver Channel, spleen channel.Effect and effect: promoting the circulation of blood diuresis, scattered strongly fragrant soothing liver-QI.Belong to invigorating blood circulation addiction The blood-activating and menstruation-regulating medicinal of classification under medicine, has enhancing uterine contraction, anticoagulation, improves the main pharmacological such as blood addiction disease.For menstruation Uncomfortable, amenorrhea, dysmenorrhea, addiction hemoperitoneum pain in puerperal, body and face edema, traumatic injury, skin infection swell and ache.
Lignum Aquilariae Resinatum: nature and flavor are pungent, bitter, tepor.Return spleen, stomach, kidney channel.Promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.For chest and abdomen Feeling of distension and oppression pain, gastrofrigid vomiting singultus, QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration.
Radix Platycodonis: nature and flavor toil is flat.It is included into lung, stomach warp.Open lung qi dispersing gas, evacuation of pus of eliminating the phlegm.Control exogenous cough, laryngopharynx swelling and pain, lung Carbuncle vomiting pus, fullness in the chest and hypochondriac pain, dysentery is suffered from abdominal pain.
Rhizoma Acori Graminei: have one's ideas straightened out, allay excitement, removing dampness to restore normal function of the stomach.Modern pharmacy research prove, Rhizoma Acori Graminei have calmness, cooling, spasmolytic, Antifungal etc. act on.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire.Modern pharmacy research prove, Radix Ophiopogonis contain multiple steroid saponin, Radix Ophiopogonis Saponin A, B, C, D, glycoside unit is ruscogenin, separately containing ophiopogonin B ', C ', D ', glycoside unit is diosgenin；Still containing multiple Huang Ketone compounds, such as methyl yellow alkanone A Radix Ophiopogonis, B, Radix Ophiopogonis flavanone A, ophiopogonone A, B, methyl ophiopogonone A, B etc., have Calm, raising immunity, fatigue-resisting function.
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping.Modern pharmacy research proves, Chuanxiong bioalkali, ferulic acid and cnidium lactone are all Having spasmolysis, ligustilide is then the main component of spasmolytic, to large intestine, dysentery (Song Nei Shi), deformation, green pus, typhoid fever, pair Bacillus typhi and vibrio cholera etc. have inhibitory action.Rhizoma Chuanxiong water logging agent (1: 3) is in vitro to some pathogenic dermatophytes also There is inhibitory action.Having obvious analgesic activity, sodium ferulate can reduce the lipid peroxidation that H2O2 and O2 causes, have oh resistant and The effect of malonaldehyde (MDA) haemolysis.Sodium ferulate can obviously reduce complement hemolysis, suppression complement component 3 b (C36) and erythrocyte membrane In conjunction with.
Poria: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Modern pharmacy research proves, Poria energy enhancing human body immunity merit Can, pachyman has obvious antitumor and protects the liver dirty effect.
Semen Ziziphi Spinosae: tranquilizing by nourishing the heart, tonifying YIN arresting sweating.Modern pharmacy research proves, Semen Ziziphi Spinosae has calmness, hypnosis, stable, town The effects such as pain.
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Modern pharmacy research proves, schisandrol extract can drop The low laboratory animal glutamate pyruvate transaminase caused by carbon tetrachloride, thioethanolamine etc. raises. wuweizisu B (schisandrin B) Tool anti-liver injury effect, also has stable, heart tonifying, enhancing immunity, the effect such as antibacterial.
Radix Salviae Miltiorrhizae: nourishing blood to tranquillize the mind, blood circulation promoting and blood stasis dispelling.Modern pharmacy research proves, Radix Salviae Miltiorrhizae contains TANSHINONES, salvianolic acid, flavone, The material such as triterpene, sterol, can strengthen myocardial contraction, improve cardiac function, not increase myocardial oxygen consumption.
Radix Curcumae: regulating qi to disperse stagnation, heart fire-clearing upset-relieving.Modern pharmacy research prove, Radix Curcumae contain volatile oil, wherein have camphene, Camphora, Curcumene, also containing curcumin, demethoxycurcumin, bisdemethoxycurcumin, turmerone and aryl turmerone, still contains shallow lake Powder, fatty oil, rubber, weld, Eucarvone and phellandrene etc., have the effects such as antifungal.
Pericarpium Citri Reticulatae: in regulating qi-flowing for strengthening spleen, tune.Modern pharmacy research proves that volatile oil contained by Pericarpium Citri Reticulatae has the thorn of gentleness to gastrointestinal tract Swash effect, can the secretion of facilitating digestion liquid, get rid of pneumatosis in intestinal tube, also there is the effect such as defying age, antioxidation.
Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Modern pharmacy research proves, Fructus Aurantii has the effect of antiallergic action.
Radix Polygalae: Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subside a swelling.Modern pharmacy research proves, Radix Polygalae have eliminate the phlegm, calmness, the merit such as analgesia Effect.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Modern pharmacy research proves, sweet Grass has antiinflammatory, antiallergic action, antianaphylactic effect, and licoflavone, Radix Glycyrrhizae extractum and enoxolone all have obvious antitussive Effect.
Herba Menthae: wind-dispelling heat-dissipating, refresh oneself, throat.Modern pharmacy research proves, Herba Menthae contains menthol, and this material has Antipruritic, pain relieving, anticorrosion, stimulate, anaesthetize, refrigerant and antiinflammatory action.
Flos Chrysanthemi: dissipate wind heat clearing away, suppressing the hyperactive liver improving eyesight.Modern pharmacy research proves, Flos Chrysanthemi has the effect of antiviral, foreign study Scholar finds, Flos Chrysanthemi has inhibitory action in various degree to herpes simplex virus poliovirus and Measles virus.This Outward, also there is the effect such as antiinflammatory, antitumor.
Compared with prior art, the invention has the beneficial effects as follows: there is dispersing the stagnated liver-QI for regulating the stomach, clearing heat and relieving fidgetness, regulating QI to remove the stagnation, nourish blood The effect calmed the nerves, can effectively treat puerpera's postpartum depression.Preparation method is simple, and good absorbing effect, and low cost, without any poison Side effect.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, all Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including following weight portion Raw material: Fructus Jujubae 10 parts, Fructus Momordicae 20 parts, Herba Lycopi 5 parts, Lignum Aquilariae Resinatum 8 parts, Herba Cistanches 10 parts, Radix Platycodonis 10 parts, Radix Angelicae Sinensis 5 parts, Rhizoma Acori Graminei 15 Part, Radix Ophiopogonis 15 parts, Rhizoma Chuanxiong 10 parts, 10 parts of Poria, Semen Ziziphi Spinosae 15 parts, Fructus Schisandrae Chinensis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Radix Curcumae 10 parts, Pericarpium Citri Reticulatae 15 Part, Fructus Aurantii 10 parts, Radix Polygalae 5 parts, 10 parts of Radix Glycyrrhizae, Herba Menthae 10 parts, Flos Chrysanthemi 10 parts, Flos Albiziae 7 parts, Flos Rosae Rugosae 4 parts.
The preparation method of the described medicament composing prescription for the nursing of puerpera's postpartum depression, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 10 mesh coarse granules, adds 50% ethanol by 5 times amount, use microwave assisted extraction methods Continuous 50 DEG C extract three times, and extract is centrifuged separating, and clean immersion is concentrated into the thick paste that relative density is 1.20；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds appropriate amylum pregelatinisatum and sodium carboxymethyl cellulose, mixing Cross 80-120 mesh sieve, add suitable quantity of water and pelletize, 60 DEG C of drying under reduced pressure, granulate, subpackage.
Embodiment 2
In the embodiment of the present invention, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including following weight portion Raw material: Fructus Jujubae 12.5 parts, Fructus Momordicae 22.5 parts, Herba Lycopi 7.5 parts, Lignum Aquilariae Resinatum 11 parts, Herba Cistanches 12.5 parts, Radix Platycodonis 12.5 parts, Radix Angelicae Sinensis 7.5 parts, Rhizoma Acori Graminei 17.5 parts, Radix Ophiopogonis 17.5 parts, Rhizoma Chuanxiong 15 parts, 15 parts of Poria, Semen Ziziphi Spinosae 17.5 parts, Fructus Schisandrae Chinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Curcumae 15 parts, Pericarpium Citri Reticulatae 17.5 parts, Fructus Aurantii 12.5 parts, Radix Polygalae 7.5 parts, 12.5 parts of Radix Glycyrrhizae, Herba Menthae 12.5 parts, Flos Chrysanthemi 12.5 Part, Flos Albiziae 9 parts, Flos Rosae Rugosae 6 parts.
The preparation method of the described medicament composing prescription for the nursing of puerpera's postpartum depression, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 20 mesh coarse granules, adds 60% ethanol by 6 times amount, use microwave assisted extraction methods Continuous 60 DEG C extract three times, and extract is centrifuged separating, and clean immersion is concentrated into the thick paste that relative density is 1.25；
(3) being vacuum dried by described thick paste, dried cream powder is broken, loads capsule, to obtain final product.
Embodiment 3
In the embodiment of the present invention, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including following weight portion Raw material: Fructus Jujubae 15 parts, Fructus Momordicae 25 parts, Herba Lycopi 10 parts, Lignum Aquilariae Resinatum 14 parts, Herba Cistanches 15 parts, Radix Platycodonis 15 parts, Radix Angelicae Sinensis 10 parts, stone Chang Pu 20 parts, Radix Ophiopogonis 20 parts, Rhizoma Chuanxiong 20 parts, 20 parts of Poria, Semen Ziziphi Spinosae 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Curcumae 20 parts, old Skin 20 parts, Fructus Aurantii 15 parts, Radix Polygalae 10 parts, 15 parts of Radix Glycyrrhizae, Herba Menthae 15 parts, Flos Chrysanthemi 15 parts, Flos Albiziae 12 parts, Flos Rosae Rugosae 9 parts.
The preparation method of the described medicament composing prescription for the nursing of puerpera's postpartum depression, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 20 mesh coarse granules, adds 60% ethanol by 6 times amount, use microwave assisted extraction methods Continuous 60 DEG C extract three times, and extract is centrifuged separating, and clean immersion is concentrated into the thick paste that relative density is 1.25；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds starch, Pulvis Talci and Magnesium Stearate proper quantity, pelletizes, compacting In flakes, coating, to obtain final product.
Embodiment 4
In the embodiment of the present invention, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including following weight portion Raw material: Fructus Jujubae 17.5 parts, Fructus Momordicae 27.5 parts, Herba Lycopi 12.5 parts, Lignum Aquilariae Resinatum 17 parts, Herba Cistanches 17.5 parts, Radix Platycodonis 17.5 parts, Radix Angelicae Sinensis 12.5 parts, Rhizoma Acori Graminei 22.5 parts, Radix Ophiopogonis 22.5 parts, Rhizoma Chuanxiong 25 parts, 25 parts of Poria, Semen Ziziphi Spinosae 22.5 parts, Fructus Schisandrae Chinensis 25 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Curcumae 25 parts, Pericarpium Citri Reticulatae 22.5 parts, Fructus Aurantii 17.5 parts, Radix Polygalae 12.5 parts, 17.5 parts of Radix Glycyrrhizae, Herba Menthae 17.5 parts, Flos Chrysanthemi 17.5 Part, Flos Albiziae 15 parts, Flos Rosae Rugosae 12 parts.
The preparation method of the described medicament composing prescription for the nursing of puerpera's postpartum depression, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 20 mesh coarse granules, adds 50-70% ethanol by 7 times amount, use microwave extracting Continuous 70 DEG C of method extracts three times, and extract is centrifuged separating, and clean immersion is concentrated into the thick paste that relative density is 1.30；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds 3 times amount aquesterilisa, filter, add account for filtrate 1/8 Ah This Ba Tian, perfusion, gland, sterilizing, obtain the oral liquid of the application.
Embodiment 5
In the embodiment of the present invention, a kind of medicament composing prescription for the nursing of puerpera's postpartum depression, including following weight portion Raw material: Fructus Jujubae 20 parts, Fructus Momordicae 30 parts, Herba Lycopi 15 parts, Lignum Aquilariae Resinatum 20 parts, Herba Cistanches 20 parts, Radix Platycodonis 20 parts, Radix Angelicae Sinensis 15 parts, stone Chang Pu 25 parts, Radix Ophiopogonis 25 parts, Rhizoma Chuanxiong 30 parts, 30 parts of Poria, Semen Ziziphi Spinosae 25 parts, Fructus Schisandrae Chinensis 30 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Curcumae 30 parts, old Skin 25 parts, Fructus Aurantii 20 parts, Radix Polygalae 15 parts, 20 parts of Radix Glycyrrhizae, Herba Menthae 10-20 part, Flos Chrysanthemi 20 parts, Flos Albiziae 17 parts, Flos Rosae Rugosae 14 parts.
The preparation method of the described medicament composing prescription for the nursing of puerpera's postpartum depression, comprises the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, river are weighed by weight Rhizome of chuanxiong, Poria, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, Mix homogeneously；
(2) mixture of step (1) is ground into 20 mesh coarse granules, adds 70% ethanol by 7 times amount, use microwave assisted extraction methods Continuous 70 DEG C extract three times, and extract is centrifuged separating, and clean immersion is concentrated into the thick paste that relative density is 1.30；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds the dextrin accounting for gross weight 1/13, mixing, pill, is dried, Obtain the micropill of the application.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim Change is included in the present invention.
Although moreover, it will be appreciated that this specification is been described by according to embodiment, but the most each embodiment only wraps Containing an independent technical scheme, this narrating mode of description is only that for clarity sake those skilled in the art should Description can also be formed those skilled in the art through appropriately combined as an entirety, the technical scheme in each embodiment May be appreciated other embodiments.

Claims (5)

1. the medicament composing prescription for the nursing of puerpera's postpartum depression, it is characterised in that include the raw material of following weight portion: red Fructus Jujubae 10-20 part, Fructus Momordicae 20-30 part, Herba Lycopi's 5-15 part, Lignum Aquilariae Resinatum 8-20 part, Herba Cistanches 10-20 part, Radix Platycodonis 10-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Acori Graminei 15-25 part, 15-25 part Radix Ophiopogonis, Rhizoma Chuanxiong 10-30 part, Poria 10-30 part, Semen Ziziphi Spinosae 15-25 part, Fructus Schisandrae Chinensis 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Radix Curcumae 10-30 part, Pericarpium Citri Reticulatae 15-25 part, Fructus Aurantii 10-20 part, Radix Polygalae 5-15 part, Radix Glycyrrhizae 10-20 Part, Herba Menthae 10-20 part, Flos Chrysanthemi 10-20 part, Flos Albiziae 7-17 part, Flos Rosae Rugosae 4-14 part.
Medicament composing prescription for the nursing of puerpera's postpartum depression the most according to claim 1, it is characterised in that include following The raw material of weight portion: Fructus Jujubae 12.5-17.5 part, Fructus Momordicae 22.5-27.5 part, Herba Lycopi's 7.5-12.5 part, Lignum Aquilariae Resinatum 11-17 part, meat Herba Cistanches 12.5-17.5 part, Radix Platycodonis 12.5-17.5 part, Radix Angelicae Sinensis 7.5-12.5 part, Rhizoma Acori Graminei 17.5-22.5 part, 17.5-Radix Ophiopogonis 22.5 parts, Rhizoma Chuanxiong 15-25 part, Poria 15-25 part, Semen Ziziphi Spinosae 17.5-22.5 part, Fructus Schisandrae Chinensis 15-25 part, Radix Salviae Miltiorrhizae 15-25 part, strongly fragrant Gold 15-25 part, Pericarpium Citri Reticulatae 17.5-22.5 part, Fructus Aurantii 12.5-17.5 part, Radix Polygalae 7.5-12.5 part, Radix Glycyrrhizae 12.5-17.5 part, Herba Menthae 12.5-17.5 part, Flos Chrysanthemi 12.5-17.5 part, Flos Albiziae 9-15 part, Flos Rosae Rugosae 6-12 part.
Medicament composing prescription for the nursing of puerpera's postpartum depression the most according to claim 1, it is characterised in that include following The raw material of weight portion: Fructus Jujubae 15 parts, Fructus Momordicae 25 parts, Herba Lycopi 10 parts, Lignum Aquilariae Resinatum 14 parts, Herba Cistanches 15 parts, Radix Platycodonis 15 parts, Radix Angelicae Sinensis 10 Part, Rhizoma Acori Graminei 20 parts, Radix Ophiopogonis 20 parts, Rhizoma Chuanxiong 20 parts, 20 parts of Poria, Semen Ziziphi Spinosae 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Curcumae 20 parts, Pericarpium Citri Reticulatae 20 parts, Fructus Aurantii 15 parts, Radix Polygalae 10 parts, 15 parts of Radix Glycyrrhizae, Herba Menthae 15 parts, Flos Chrysanthemi 15 parts, Flos Albiziae 12 parts, Flos Rosae Rugosae 9 Part.
4. a preparation method for the medicament composing prescription for the nursing of puerpera's postpartum depression as described in claim 1-3 is arbitrary, It is characterized in that, comprise the following steps:
(1) Fructus Jujubae, Fructus Momordicae, Herba Lycopi, Lignum Aquilariae Resinatum, Herba Cistanches, Radix Platycodonis, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Ophiopogonis, Rhizoma Chuanxiong, Fu are weighed by weight Siberian cocklebur, Semen Ziziphi Spinosae, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, Radix Curcumae, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Polygalae, Radix Glycyrrhizae, Herba Menthae, Flos Chrysanthemi, Flos Albiziae and Flos Rosae Rugosae, mixing Uniformly；
(2) mixture of step (1) is ground into 10-20 mesh coarse granule, adds 50-70% ethanol by 5-7 times amount, use microwave extracting Continuous 50-70 DEG C of method extracts three times, and extract is centrifuged separating, and it is 1.20-1.30's that clean immersion is concentrated into relative density Thick paste；
(3) being vacuum dried by described thick paste, dried cream powder is broken, adds proper auxiliary materials, makes corresponding dosage form.
Medicament composing prescription for the nursing of puerpera's postpartum depression the most according to claim 1, it is characterised in that step (3) Middle adjuvant adds appropriate amylum pregelatinisatum and sodium carboxymethyl cellulose, mixes 80-120 mesh sieve, adds suitable quantity of water and pelletizes, 60 DEG C of decompressions It is dried, granulate, subpackage.
CN201610791359.4A 2016-08-31 2016-08-31 A kind of medicament composing prescription for the nursing of puerpera's postpartum depression and preparation method Pending CN106266962A (en)

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Application publication date: 20170104