CN106266718A - Preparation method of scourge-clearing toxin-vanquishing powder - Google Patents
Preparation method of scourge-clearing toxin-vanquishing powder Download PDFInfo
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- CN106266718A CN106266718A CN201610849995.8A CN201610849995A CN106266718A CN 106266718 A CN106266718 A CN 106266718A CN 201610849995 A CN201610849995 A CN 201610849995A CN 106266718 A CN106266718 A CN 106266718A
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Abstract
The invention relates to a preparation method of scourge-clearing toxin-vanquishing powder, which belongs to the technical field of medicines and is mainly prepared by the following steps: firstly, the used preparation raw materials: cortex Mori, radix Isatidis, rhizoma Phragmitis, radix Codonopsis, Atractylodis rhizoma, semen Persicae, Carthami flos, radix Paeoniae Rubra, herba plantaginis, flos Lonicerae, fructus forsythiae, Atractylodis rhizoma, radix Angelicae Dahuricae, Os Draconis, Poria, radix Arnebiae, and Glycyrrhrizae radix; secondly, mixing the medicines, heating the mixture with 3 liters of water, boiling and decocting the mixture for 30 to 50 minutes; thirdly, standing and clarifying the decoction for 30 to 40 minutes to obtain clarified liquid medicine after separation; fourthly, the clear liquid medicine is put into a drying room to be sealed, dried and concentrated; fifthly, drying the clear liquid medicine to be thick paste, taking out, mixing with a proper amount of starch, and uniformly stirring to form soft medicine paste; sixthly, placing the soft medicinal flour mud into a drying room again for low-temperature drying to obtain medicinal flour mud blocks; and seventhly, crushing the medicinal flour paste blocks and pressing into granular medicines.
Description
Technical field
The present invention relates to a kind for the treatment of Chinese patent medicine being applied to treat porcine rotavirus class disease, belong to veterinary drug technology neck
Territory.
Background technology
Colyliform viral disease is the pig acute infectious intestinal disease caused by porcine rotavirus, cardinal symptom be anorexia, vomiting, under
Dysentery, middle pig and big pig are inapparent infection, do not have symptom.Pathogen, in addition to porcine rotavirus, is divided from child, calf, lamb, colt
From rotavirus also can infect piglet and cause symptom in various degree.The resistance of colyliform poison environment to external world is relatively strong, 18
～in the feces of 20 degrees Celsius and milk, 7～9 months can be survived..
Colyliform poison is primarily present in disease and the digestive tract of band poison pig, after being discharged to external environment with feces, pollutes feedstuff, drink
Water, pad grass and soil etc., make susceptible pig infect through digestive tract approach.The toxin expelling time can last for days, can serious environment pollution, add
Virus environment to external world have tanacity resistance, make rotavirus become pig, middle pig, between iterative cycles infect, prick for a long time
Root pig farm.It addition, people and other animals also can disseminate infection.Primary disease is multiple is born in late fall, winter and early spring.The pig at various ages
All can infect, the most infect and adaptive immune due to most of Adult Pigs in Prevalent district.Therefore, the pig that falls ill be mostly 8 week old with
Under piglet, the piglet that age in days is the least, sickness rate is the highest, and sickness rate is generally 50%～80%, within case fatality rate is generally 10%.
Rotavirus is generally 12～24 hours incubation period.Often endemic conditions.Just spirit is depressed, and inappetence is reluctant
Walking about, some is vomitted after sucking the breast, and then suffers from diarrhoea, and feces is yellow, Lycoperdon polymorphum Vitt or black, for water sample or pasty state.Symptom light
Heavily it is decided by age in days, immune state and the environmental condition of morbidity, lacks the piglet symptom of raw few days after of maternal antibody protection
Weight, when ambient temperature decline or secondary colibacillosis, often makes exacerbation of symptoms, and case fatality rate increases.Usual 10～21 age in days piglets
Symptom relatively light, the diarrhoea a few days gets final product rehabilitation, and 3～8 week old piglet symptoms are lighter, and Adult Pig is inapparent infection.
Pathological change pathological changes is mainly at digestive tract, and coat of the stomach relaxes, and is full of ziega and milk, and intestinal tube is thinning, and small bowel is thin
Being translucent, content is aqueous, and in lark or grey black, intestinal villi shortens, enteric hemorrhage sometimes, the intestinal system enlargement of lymph node
Greatly.
Primary disease mostly occurs in cold season, and disease mostly is children's age, and cardinal symptom is diarrhoea.According to these features, at the beginning of can making
Step diagnosis.But the reason causing diarrhoea is a lot, in naturally falling ill, often it is found to have rotavirus and coronavirus or large intestine
The mixed infection of bacillus, makes diagnosis of complex.Therefore, it is necessary to just can be made a definite diagnosis by lab testing.Disease is taked to send out latter 25 hours
Interior feces, loads penicillin empty bottle, send lab testing.The method of world health organisation recommendations is that sandwich assay enzyme linked immunological is inhaled
Adhesion test, it is possible to do Electronic Speculum or immunoelectronmicroscopy, all can reach a conclusion rapidly.Before, during and after also can taking small intestinal each one section,
Freezing, for fluorescent antibody inspection.
The treatment and prevention of porcine rotavirus.1, treatment: at present without the medicine of specially good effect.Find to stop immediately feeding breast,
Freely drink to sick pig with Fructus Vitis viniferae saline or compound recipe glucose solution.Meanwhile, carry out symptomatic treatment, such as the astringing to arrest diarrhea agent that comes into operation,
Use antibacterials, to prevent secondary bacterial sexuality from contaminating.Typically all can obtain good result.2, prevention: rely primarily on reinforcement and raise
Support management, carry out general veterinary antiepizootic measure in real earnest, strengthen the resistance of sum.In Prevalent district, available colyliform poison oil adjuvant
Sow or piglet are inoculated by inactivated vaccine or porcine rotavirus weak poison bivalent Seedling.Oil adjuvant Seedling in farrowing sow just before giving birth before
30 days, intramuscular injection 2 milliliters；Piglet respectively injects 1 time in 7 ages in days and 21 ages in days, injection site Houhai acupoint (root of the tail and anus it
Between at recess) subcutaneous, inject 0.5 milliliter for each every.Attenuate vaccine is intramuscular injection 1 time respectively in the most first 5 weeks and 2 weeks, every time
1 milliliter every.Newborn piglet to be made early eats colostrum, accepts the protection of maternal antibody, to reduce morbidity and to weaken disease.
Summary of the invention
With Chinese medicine viewpoint analysis porcine rotavirus, belong to the evil poison of infection, poison enters nutrient blood, interior retention and fumigation of damp-heat inside the body, damp and hot foul
Xiang Bo, battalion defend imbalance, treat rotavirus, should be with heat-clearing and toxic substances removing, counteracting toxic substances of getting rid of evils, soothing liver and strengthening spleen, harmonizing yingfen and weifen, invigorating QI to relieve exhaustion
Chinese Medicine and Clavicular smelting is treated.
According to upper analysis, the manufacture method of a kind of antipyretic and antitoxic powder solves problem and is adopted the technical scheme that by the following step
Be made: making raw material one, used: Cortex Mori 15 grams, Radix Isatidis 12 grams, Rhizoma Phragmitis 10 grams, Radix Codonopsis 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams,
10 grams of Semen Persicae, 6 grams of Flos Carthami, Radix Paeoniae Rubra 10 grams, Herba Plantaginis 10 grams, Flos Lonicerae 12 grams, Fructus Forsythiae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, the Radix Angelicae Dahuricae 10 grams, dragon
12 grams of bone, 15 grams of Poria, Radix Arnebiae (Radix Lithospermi) 10 grams, 7 grams of Radix Glycyrrhizae；Two, each medicament mixed is heated boiled decoction 30 ~ 50 minutes with 3 liters of water；
Three, carry out standing clarification after separating decoction liquor and within 30 to 40 minutes, become clarification medicinal liquid；Four, seal in clarification medicinal liquid is put into drying shed
Closing and be dried except water concentrates, desiccant is temperature 10 DEG C ~ 25 DEG C in quick lime, drying shed；Five, clarification medicinal liquid is dried to thick-pasty
Take out, be mixed into appropriate amount of starch and stir and become soft powder mud；Six, soft powder mud is cut into small pieces after diameter 1 ~ 2 centimetre again
Secondary be placed in drying shed in carry out cold drying, until hardening to powder clod；Seven, carry out powder clod pulverizing as mixing medicine
Powder, then mixed powder is suppressed into particle medicinal；Eight, by particle medicinal bottling seal.
Each herbal nature in the manufacture method of lower a kind of antipyretic and antitoxic powder of surface analysis.Cortex Mori (Morus alba L.),
Another name Cortex Mori, Radix Mori skin, Cortex Mori, Morus alba skin, micro-have a bean stink smell, sweet and slightly bitter taste, and, skin depth white with color, mealiness foot person are preferred.
Having blood sugar lowering, diuresis, human body HIV (human immunodeficiency virus) HIV, antibacterial grade acts on.Radix Isatidis is named again: indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Radix Clerodenri Cyrtophylli,
It it is a kind of conventional Chinese crude drug that dispels the wind；There is heat-clearing and toxic substances removing, removing heat from blood detumescence, effect of sore-throat relieving.Rhizoma Phragmitis heat clearing away blood fire, kind clearing heat in QI system divides
Heat, for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.The primary efficacy of Radix Codonopsis is QI invigorating.The most suitable
For fatigue and weakness usually, lassitude.Voice is overcast, conscious breathes hard, the slightly movable insufficiency of lung-QI weak person with regard to dyspnea with rapid and short breath.Lay particular emphasis on
The people of deficiency of spleen-QI and stomach-QI, myasthenia of limbs, inappetence.Rhizoma Atractylodis Macrocephalae effect with effect the Rhizoma Atractylodis Macrocephalae effect mainly have calmness, vasodilation,
Anticoagulant, anti-gastric-ulcer, hepatic cholagogic, diuresis, strong, improve immunity, antioxidation, antibacterial etc..Flos Carthami is warm in nature, acrid in the mouth, invigorate blood circulation
Latus rectum, eliminating stasis to stop pain, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, be suitable for various varicosis, tip
Neuritis, blood circulation is bad, lower limb numbness or the mass formed by blood stasis such as livid purple.Radix Paeoniae Rubra has the functions such as clots absorbing, pain relieving, removing heat from blood, detumescence, controls
The accumulation of the stagnant amenorrhea of the stasis of blood, hernia abdominal mass, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.The merit of Herba Plantaginis
Effect and effect: clearing away heat and promoting diuresis, removing heat from blood, removing toxic substances；Main accumulation of heat in the urinary bladder, dysuria,;Stranguria with turbid discharge leukorrhagia, heat-damp in summer dysentery,;Liver-heat mesh
Red,;Carbuncle sore tumefacting virus.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times, its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach,
Fragrance thoroughly reaches and can be eliminating evil, Flos Lonicerae can dispelling wind-heat, also be apt to removing summer-heat blood poison, for various febrile diseases, as fever of the body, dermexanthesis,
Send out speckle.Fructus Forsythiae heat clearing away, removing toxic substances, eliminating stagnation, detumescence, control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.The Rhizoma Atractylodis Macrocephalae is mended
Spleen, stomach reinforcing, dampness, and in, antiabortive, control deficient QI of the spleen and stomach, anorexia, the few gas of asthenia, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice,
Arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, nausea is uneasy.The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature, return lung, spleen, stomach, large intestine channel, function is dispeled the wind solution
Table, dispersing cold for relieving pain, dehumidifying are sensible, detumescence and apocenosis, and modern pharmacological research proves, the Radix Angelicae Dahuricae is made except having antipyretic, analgesia, antiinflammatory etc.
With.Os Draconis tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, and promoting tissue regeneration and ulcer healing controls infantile convulsion demented, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous perspiration
Night sweat, stranguria with turbid discharge of passing out semen, to tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not closes up.Doctor thinks that Poria slightly sweet flavor is put down, and enters
The heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Poria can control dysuria, edema distension, expectorant
Drink cough with dyspnea, vomiting.Radix Arnebiae (Radix Lithospermi) removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances, controls warm macule, jaundice due to damp-heat, purpura, tells, is defeated in battle, hematuria, stranguria with turbid discharge,
Constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Radix Glycyrrhizae tabellae be relieving cough and expelling phlegm medicine, effect rather extensively, Chinese medicine decoction and in
In patent medicine compatibility, commonly use its QI invigorating strengthening the spleen and middle emergency, effect of coordinating the actions of various ingredients in a prescription.
The manufacture method beneficial effect of the invention of a kind of antipyretic and antitoxic powder is: the manufacture method of a kind of antipyretic and antitoxic powder with
Chinese medicine viewpoint analysis porcine rotavirus, belongs to the evil poison of infection, poison enters nutrient blood, and interior retention and fumigation of damp-heat inside the body, damp and hot foul phase are rich, battalion defends mistake
Adjust, treat rotavirus, should be with heat-clearing and toxic substances removing, counteracting toxic substances of getting rid of evils, soothing liver and strengthening spleen, harmonizing yingfen and weifen, the Chinese Medicine and Clavicular smelting of invigorating QI to relieve exhaustion
Treating, and make patent medicine granule, it is simple to treatment uses, application effect is notable.
Detailed description of the invention
Below the manufacture method of a kind of antipyretic and antitoxic powder is further implemented explanation.
It is to be made by the following step that the manufacture method of a kind of antipyretic and antitoxic powder produces a box granular medicament: one,
Making raw material used: Cortex Mori 15 grams, Radix Isatidis 12 grams, Rhizoma Phragmitis 10 grams, Radix Codonopsis 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 10 grams of Semen Persicae, Flos Carthami
6 grams, Radix Paeoniae Rubra 10 grams, Herba Plantaginis 10 grams, Flos Lonicerae 12 grams, Fructus Forsythiae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, the Radix Angelicae Dahuricae 10 grams, Os Draconis 12 grams, Poria 15
Gram, Radix Arnebiae (Radix Lithospermi) 10 grams, 7 grams of Radix Glycyrrhizae；Two, each medicament mixed is heated boiled decoction 30 ~ 50 minutes with 3 liters of water；Three, decoction liquor is separated
After carry out stand clarification within 30 to 40 minutes, become clarification medicinal liquid；Four, put clarification medicinal liquid into drying shed inner sealing to be dried except water is dense
Contracting, desiccant is temperature 10 DEG C ~ 25 DEG C in quick lime, drying shed；Five, clarification medicinal liquid is dried and takes out to thick-pasty, is mixed into suitable
Amount starch also stirs and becomes soft powder mud；Six, soft powder mud is cut into small pieces after diameter 1 ~ 2 centimetre and is again placed in drying shed
Inside carry out cold drying, until hardening to powder clod；Seven, carrying out powder clod pulverizing is mixed powder, then will mixing
Medicated powder is suppressed into particle medicinal；Eight, by particle medicinal bottling seal.
Claims (1)
1. a manufacture method for antipyretic and antitoxic powder, is characterized in that being made by the following step: making raw material one, used:
Cortex Mori 15 grams, Radix Isatidis 12 grams, Rhizoma Phragmitis 10 grams, Radix Codonopsis 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, 10 grams of Semen Persicae, 6 grams of Flos Carthami, Radix Paeoniae Rubra 10 grams, car
First careless 10 grams, Flos Lonicerae 12 grams, Fructus Forsythiae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, the Radix Angelicae Dahuricae 10 grams, Os Draconis 12 grams, 15 grams of Poria, Radix Arnebiae (Radix Lithospermi) 10 grams, sweet
Grass 7 grams；Two, each medicament mixed is heated boiled decoction 30 ~ 50 minutes with 3 liters of water；Three, carry out after separating decoction liquor standing clarification
Within 30 to 40 minutes, become clarification medicinal liquid；Four, clarification medicinal liquid being put into drying shed inner sealing be dried except water concentrates, desiccant is calculogenesis
Temperature 10 DEG C ~ 25 DEG C in ash, drying shed；Five, clarification medicinal liquid is dried and takes out to thick-pasty, is mixed into appropriate amount of starch and stirs
Become soft powder mud；Six, soft powder mud is cut into small pieces after diameter 1 ~ 2 centimetre in being again placed in drying shed and carries out cold drying,
Until hardening to powder clod；Seven, carrying out powder clod pulverizing is mixed powder, then mixed powder is suppressed into granule
Medicine；Eight, by particle medicinal bottling seal.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406070A (en) * | 2011-10-25 | 2012-04-11 | 上海交通大学 | Feed additive made of Chinese herbal medicine and used for reducing respiratory tract diseases of piglets |
| CN103520570A (en) * | 2013-10-16 | 2014-01-22 | 谭钦文 | Traditional Chinese medicine for treating liver depression forming fire syndrome type acne disease |
| CN104940692A (en) * | 2015-06-28 | 2015-09-30 | 李先强 | Traditional Chinese medicine composition for treating marburg hemorrhagic fever |
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2016
- 2016-09-26 CN CN201610849995.8A patent/CN106266718A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406070A (en) * | 2011-10-25 | 2012-04-11 | 上海交通大学 | Feed additive made of Chinese herbal medicine and used for reducing respiratory tract diseases of piglets |
| CN103520570A (en) * | 2013-10-16 | 2014-01-22 | 谭钦文 | Traditional Chinese medicine for treating liver depression forming fire syndrome type acne disease |
| CN104940692A (en) * | 2015-06-28 | 2015-09-30 | 李先强 | Traditional Chinese medicine composition for treating marburg hemorrhagic fever |
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