CN104940692A - Traditional Chinese medicine composition for treating marburg hemorrhagic fever - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating a marburg hemorrhagic fever. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 12 parts of bamboo shavings, 20 parts of cornu gorais, 10 parts of rhizoma phragmitis, 10 parts of radix scrophulariae, 15 parts of astragalus membranaceus, 10 parts of peach kernel, 6 parts of flowers carthami, 10 parts of red peony roots, 10 parts of dried radix rehmanniae, 12 parts of honeysuckle flower, 10 parts of fructus forsythiae, 10 parts of white atractylodes rhizome, 10 parts of radix angelicae, 12 parts of ossa draconis, 20 parts of concha ostreae, 10 parts of lithospermum and 7 parts of liquorice. The marburg hemorrhagic fever is analyzed by an inventor with the points of traditional Chinese medicine, and belongs to external infection of toxin, toxin entering construction blood, internal damp-heat stagnation and steaming, middle energizer dampness-heat, deficiency of qi and blood, and internal blockade and external collapse; the technical scheme of traditional Chinese medicine combination treatment for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, cooling blood, stopping bleeding, eliminating dampness, clearing away turbidness, and invigorating qi for relieving desertion is adopted; and an obvious curative effect is obtained.

Description

A kind of Chinese medicine composition medicine for the treatment of Ma Erbao hemorrhagic fever

Technical field

The present invention relates to a kind of Chinese medicine composition medicine for the treatment of Ma Erbao hemorrhagic fever, belong to medicine technology field.

Background technology

1967, breaking out a kind of in Germany and Yugoslavia take heating as the disease disease of cardinal symptom, this disease disease makes people progressively weak rapidly, started to occur serious watery diarrhea about the 3rd day, stomachache and cramp, nausea and vomiting, many patients occurred that severe haemorrhage showed in 5 days to 7 days, and usually there is the hemorrhage of certain form in fatal case, often that multiple position is hemorrhage, at the severe stage of disease, patient continues to occur hyperpyrexia, entanglement can be caused when relating to central nervous system, easy on the trigger and aggressive behavior, a lot of case occurs dead, the disease-producing pathogens of this disease is filamentous virus Wladyslaw Komar fort virus, be called Ma Erbao hemorrhagic fever.Marburg hemorrhagic fever be by from the serious high fatal disease causing a kind of virus of the same section of the virus of ebola hemorrhagic fever to cause.Observe under an electron microscope, these viral display shapes resemble stretched filament, are sometimes coiled into the particle of odd shape, thus are named as filamentous virus section.These viruses belong to the most strong pathogen of known infection people.The non-human primate and the patient that infect virus are major source of infection.Usual elder generation by infected non-human primate (as grivet) by viral communication to people, and then be transmitted to other Healthy Peoples by patient.The infectiousness of Marburg virus is extremely strong, and the heavier patient infection's property of symptom is stronger, and incubation period, the infectiousness of patient was weak.People is not the part in viral Natural Circulation, just accidentally infected.This virus it be not immediately clear at the reservoir of occurring in nature.Mainly propagate through close contact, namely contact the corpse of animals died of illness and patient, and the blood of infection animal and patient, secretions, Excreta, vomitus etc., through mucous membrane and damaged skin are propagated.In African epidemic-stricken area, because contacting patient's corpse during funeral, once repeatedly there is primary disease and breaking out.Route of transmission, also can cause hospital infection and laboratory infection by close contact.In addition, by using contaminated syringe etc. to cause iatrogenic infection.Have report, patient, within clinical rehabilitation March, still can detect Marburg virus in seminal fluid, therefore, and the probability that existence is propagated.

Prevention and therapy for Ma Erbao hemorrhagic fever: once find that case is reported immediately, tightly isolate, Close contacts also should be observed and isolate.Ma Erbao hemorrhagic fever there is no specific treatment medicine, mainly relies on early discovery, early stage isolation, symptomatic treatment and positive Supporting Therapy to it.Supporting Therapy: should lie up, strictly implement disinfectant measure, to avoid propagating; Keep water, electrolyte and acid-base balance.Suit the medicine to the illness and complications Treatment: comprise bring down a fever, calmness, oxygen therapy, hemostasis, protection important organ function etc.Antiviral therapy: result of use is best in first 6 days of the course of disease, such as ribavirin intravenously administrable, first dose of 30mg/kg, later by 15mg/kg medication in every 6 hours 4 days, then continues medication 6 days by every 8 hours 8mg/kg, receives certain curative effect.

Summary of the invention

Although Ma Erbao is hemorrhage is the result that viral communication is attacked, but the immunity of the body constitution reason of people and people, power of resisting also are lowly liable to infection reasons, with Chinese medicine viewpoint analysis Ma Erbao hemorrhagic fever, belong to the evil poison of diseases caused by exogenous pathogenic factor, poison enters nutrient blood, interior retention and fumigation of damp-heat inside the body, damp and hot middle resistance, deficiency of vital energy blood are weak, unconsciousness and collapse, treatment Ma Erbao hemorrhagic fever, should treat with the Chinese Medicine and Clavicular smelting of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, cooling blood for hemostasis, removing damp and turbid, invigorating QI to relieve exhaustion.

A kind of Chinese medicine composition medicine of the Ma Erbao for the treatment of hemorrhagic fever combines by each Chinese medicine quality part ratio below: Caulis Bambusae In Taenia 12 parts, Cornu Naemorhedi 20 parts, Rhizoma Phragmitis 10 parts, Radix Scrophulariae 10 parts, the Radix Astragali 15 parts, 10 parts, Semen Persicae, 6 parts, Flos Carthami, Radix Paeoniae Rubra 10 parts, 10 parts, the Radix Rehmanniae, Flos Lonicerae 12 parts, Fructus Forsythiae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Angelicae Dahuricae 10 parts, Os Draconis 12 parts, Concha Ostreae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, 7 parts, Radix Glycyrrhizae.

Lower surface analysis is a kind of treats each herbal nature in the Chinese medicine composition medicine of Ma Erbao hemorrhagic fever.Caulis Bambusae In Taenia function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting, and holds expectorant, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement under the arm for phlegm-heat cough, gallbladder fire.Effect of Chinese medicine Cornu Naemorhedi: heat clearing away is relieving convulsion, eliminating stasis to stop pain, before Saigae Tataricae is as wild watching for animals under topic, Cornu Naemorhedi can substitute Cornu Saigae Tataricae effectively, and effect is more or less the same.Rhizoma Phragmitis heat clearing away blood fire, kind clearing heat in QI system, for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Radix Scrophulariae cures mainly epidemic febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.Chinese medicine astragalus invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, diuresis, granulation promoting.The Semen Persicae promoting blood stasis of blood, moisturizes laxation, controls amenorrhea ， mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Flos Carthami is warm in nature, acrid in the mouth, latus rectum of invigorating blood circulation, eliminating stasis to stop pain, and for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the mass formed by blood stasis such as livid purple.Radix Paeoniae Rubra has the functions such as clots absorbing, pain relieving, removing heat from blood, detumescence, controls the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, suffer from abdominal pain, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.Radix Rehmanniae yin nourishing, clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis, for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times, its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach, fragrance reaches thoroughly can be eliminating evil, Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out speckle.Fructus Forsythiae heat clearing away, removing toxic substances, eliminating stagnation, detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Rhizoma Atractylodis Macrocephalae spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, and nausea is uneasy.The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature, return lung, spleen, stomach, large intestine channel, function expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifying are sensible, detumescence and apocenosis, and modern pharmacological research proves, the Radix Angelicae Dahuricae is except having the effects such as antipyretic, analgesia, antiinflammatory.Os Draconis tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing, controls infantile convulsion demented, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.Concha Ostreae convergence is astringent or styptic treatment for spontaneous sweating, heat clearing away tonifying YIN, softening and eliminating sputum, yin fluid astringing YANG hyperactivity suppressing, cure mainly night sweat, spontaneous perspiration, pass out semen, have loose bowels, metrorrhagia, leukorrhagia, infantile convulsion, dizzy, scrofula sucutaneous nodule, hernia abdominal mass, pained, carbuncle etc.Radix Arnebiae (Radix Lithospermi) removing heat from blood, invigorates blood circulation, heat clearing away, and removing toxic substances, controls warm macule, jaundice due to damp-heat, purpura, tell, is defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Radix Glycyrrhizae tabellae be relieving cough and expelling phlegm medicine, effect rather extensively, in Chinese medicine decoction and Chinese patent medicine compatibility, its QI invigorating strengthening the spleen conventional and middle emergency, coordinating the actions of various ingredients in a prescription effect.

A kind of Chinese medicine composition medicine beneficial effect of the invention of the Ma Erbao for the treatment of hemorrhagic fever is: a kind of Chinese medicine composition medicine for the treatment of Ma Erbao hemorrhagic fever is the pathogeny of Ma Erbao hemorrhagic fever with the viewpoint analysis of Chinese medicine, belong to the evil poison of diseases caused by exogenous pathogenic factor, poison enters nutrient blood, interior retention and fumigation of damp-heat inside the body, damp and hot middle resistance, deficiency of vital energy blood are weak, unconsciousness and collapse, treat with the Chinese Medicine and Clavicular smelting of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, cooling blood for hemostasis, removing damp and turbid, invigorating QI to relieve exhaustion, have received obvious curative effect.

Detailed description of the invention

Further implementation is done to a kind of Chinese medicine composition medicine of the Ma Erbao for the treatment of hemorrhagic fever below.

It is combine by each Chinese medicine quality ratio below that a kind of Chinese medicine composition medicine of the Ma Erbao for the treatment of hemorrhagic fever is applicable to a dose drug that a Ma Erbao hemorrhagic fever patient takes: Caulis Bambusae In Taenia 12 grams, Cornu Naemorhedi 20 grams, Rhizoma Phragmitis 10 grams, Radix Scrophulariae 10 grams, the Radix Astragali 15 grams, 10 grams, Semen Persicae, 6 grams, Flos Carthami, Radix Paeoniae Rubra 10 grams, 10 grams, the Radix Rehmanniae, Flos Lonicerae 12 grams, Fructus Forsythiae 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, the Radix Angelicae Dahuricae 10 grams, Os Draconis 12 grams, Concha Ostreae 20 grams, Radix Arnebiae (Radix Lithospermi) 10 grams, 7 grams, Radix Glycyrrhizae.

A kind of using method for the treatment of the Chinese medicine composition medicine of Ma Erbao hemorrhagic fever: one, an above-mentioned dose drug (except Cornu Naemorhedi) is soaked drenched post-heating by proper amount of clear water and decoct into medicinal liquid; Two, by Cornu Naemorhedi pocket knife scraper plane powdered, the baking of powder high humidity or pot are fried and slightly make detonation, take after mixing it with water together with the medicinal liquid of previous step gained, within two days, take a dosage, patient with severe symptoms takes a dosage for one day, and symptom alleviates rear dose and can reduce in right amount.

A kind of Chinese medicine composition medicine of the Ma Erbao for the treatment of hemorrhagic fever is not only applicable to Ma Erbao hemorrhagic fever, all effective in cure for the serious conditions of a lot of viral infection, hemorrhagic conditions, patient's utility efficiency of hemorrhage fever is accompanied, treated effect 100%, treatment cure rate 95% to tens viral infections.

Claims (1)

1. treat a Chinese medicine composition medicine for Ma Erbao hemorrhagic fever, it is characterized in that combining by each Chinese medicine quality part ratio below: Caulis Bambusae In Taenia 12 parts, Cornu Naemorhedi 20 parts, Rhizoma Phragmitis 10 parts, Radix Scrophulariae 10 parts, the Radix Astragali 15 parts, 10 parts, Semen Persicae, 6 parts, Flos Carthami, Radix Paeoniae Rubra 10 parts, 10 parts, the Radix Rehmanniae, Flos Lonicerae 12 parts, Fructus Forsythiae 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Angelicae Dahuricae 10 parts, Os Draconis 12 parts, Concha Ostreae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, 7 parts, Radix Glycyrrhizae.