CN102920955B - External traditional Chinese medicine composition for treating dermatophytosis, preparation method and application - Google Patents
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an external traditional Chinese medicine composition for treating dermatophytosis, a preparation method and application. The external traditional Chinese medicine composition provided by the invention comprises achyranthes aspera, radix sophorae flavescentis, sutellaria baicalensis, fructus cnidii, dandelion, radix bupleuri, radix ophiopogonis, folium isatidis, bighead atractylodes rhizome, houttuynia cordata, radix scrophulariae, radix puerariae, gastrodia elata, liquorice, burdock, lithospermum, honeysuckle, polygonum cuspidatum, cyrtomium fortunei, smoked plum, fructus forsythiae, panax notoginseng, antifebrile dichroa, sweet wormwood, astragalus mongholicus, felwort, semen coicis and betel nut. The external traditional Chinese medicine composition has obvious curative effect on the dermatophytosis, and has the advantages that roots cause and symptoms are simultaneously treated, curing rate is high, and the recurrence rate is small, and the like.
Description
Technical field
The present invention relates to technical field of Chinese medicines, relate in particular to a kind of external medicine composition that is used for the treatment of beriberi.
Background technology
Beriberi is medically claiming again " tinea pedis ", and being commonly called as " tinea pedis, " is foot fungus infection.Show as between toe or vola skin pruritus, erythema, pimple, decortication, or have blister, seriously can be rotten to the corn, ooze out.As control not in time can involve other positions, cause tinea corporis, tinea cruris or " tinea unguium ".Medically conventionally beriberi is divided to three types: erosive type, vesicle, keratinization type beriberi.Erosive type: be apt to occur between the 3rd and the four, four and the 5th toe.From the beginning of moist between toe, dipping turns white or plays phlysis, and after dry desquamation, peelling off scurf is rotten to the corn face moistening, flushing, odd itching, easily secondary infection.Vesicle: be apt to occur in sufficient edge.From the beginning of being the full phlysis of wall thickness, the be fused into bulla having, bleb liquid is transparent, around without blush.Consciously very itch, after scratching often because secondary infection causes erysipelas, lymphangitis etc.Keratinization type: be apt to occur in heel.Main manifestations is that skin is thick thick and dry, keratinization desquamation, scratches where it itches, and easily chaps.This type is without vesicle and suppuration, and the course of disease is slow, does not heal for many years.
Western medicine beriberi, often treats with antifungal drug, and conventional product has daktarin, Lan Meishu, Pevisone, PIKANGWANG and ZUGUANG SAN etc.Clinical effectiveness is better, but easily causes that feel dyes.In addition, majority is to cure the symptoms, not the disease, and easily recurrence after drug withdrawal is cut heavier patient and is difficult to cure.In middle medical knowledge is disputed, from etiology and pathology, beriberi belongs to soaks the disease that is difficult to winding flesh table and cause for a long time.But from current practical situation, no matter be medicine for external use according to theory of Chinese medical science or according to the medicine of the treatment beriberi of the theoretical development of doctor trained in Western medicine, and existing beriberi is all difficult to reach the beriberic object of radical cure.How in traditional Chinese medical science field, to seek a kind of new drug regimen, can reach evident in efficacy, treating both the principal and secondary aspects of a disease, cure rate is high, is difficult for recurrence, has become a problem that enjoys people to pay close attention to.
Summary of the invention
Technical problem to be solved by this invention is to be to provide a kind of novel external medicine composition of beriberi and preparation method thereof that is used for the treatment of, adopt this Chinese medicine composition to have treating beri-beri evident in efficacy, treating both the principal and secondary aspects of a disease, cure rate is high, is difficult for the advantages such as recurrence.
In order to solve the problems of the technologies described above, the invention provides a kind of external medicine composition that is used for the treatment of beriberi, it comprises: Radix Achyranthis, Radix Sophorae Flavescentis, Radix Scutellariae, Fructus Cnidii, Herba Taraxaci, Radix Bupleuri, Radix Ophiopogonis, Folium Isatidis, the Rhizoma Atractylodis Macrocephalae, Herba Houttuyniae, Radix Scrophulariae, Radix Puerariae, Rhizoma Gastrodiae, Radix Glycyrrhizae, Fructus Arctii, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Rhizoma Polygoni Cuspidati, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Radix Notoginseng, Radix Dichroae, Herba Artemisiae Annuae, the Radix Astragali, Radix Gentianae, Semen Coicis, Semen Arecae.
Wherein, the ratio of weight and number of the each component in described Chinese medicine composition is, Radix Achyranthis 20～30 weight portions, Radix Sophorae Flavescentis 10-20 weight portion, Radix Scutellariae 15～20 weight portions, Fructus Cnidii 2～6 weight portions, Herba Taraxaci 10～15 weight portions, Radix Bupleuri 10-20 weight portion, Radix Ophiopogonis 4～10 weight portion, Folium Isatidis 4～6 weight portions, Rhizoma Atractylodis Macrocephalae 10-15 weight portion, Herba Houttuyniae 10～15 weight portions, Radix Scrophulariae 10-20 weight portion, Radix Puerariae 20～30 weight portions, Rhizoma Gastrodiae 10-15 weight portion, Radix Glycyrrhizae 15～20 weight portions, Fructus Arctii 10～20 weight portions, Radix Arnebiae (Radix Lithospermi) 10-15 weight portion, Flos Lonicerae 1～10 weight portion, Rhizoma Polygoni Cuspidati 10-20 weight portion, Rhizoma Osmundae 10～12 weight portions, Fructus Mume 4～6 weight portions, Fructus Forsythiae 10～20 weight portions, Radix Notoginseng 10-15 weight portion, Radix Dichroae 10-15 weight portion, Herba Artemisiae Annuae 1-10 weight portion, Radix Astragali 5-10 weight portion, Radix Gentianae 5～10 weight portions, Semen Coicis 10-15 weight portion, Semen Arecae 10～50 weight portions.
For solving the problems of the technologies described above, the present invention also provides a kind of external medicine composition that is used for the treatment of beriberi, and described Chinese medicine composition is prepared from by the following method:
The first step, mixes each component pulverize in described ratio;
Second step, the mixture after the pulverizing that the first step is obtained adds and in ethanol, soaks and decoct, and merging decoction liquor is also concentrated into thick shape;
The 3rd step, the thick liquid matter that second step is obtained adds a small amount of ethanol, Oleum Sesami, vinegar, and fully stirring and evenly mixing becomes paste.
For solving the problems of the technologies described above, the present invention also provides the preparation method of above-mentioned external medicine composition, and it comprises:
The first step, mixes each component pulverize in described ratio;
Second step, the mixture after the pulverizing that the first step is obtained adds and in ethanol, soaks and decoct, and merging decoction liquor, filters and is concentrated into thick shape; Gained thick liquid can directly use, optional, can carry out the 3rd step processing;
The 3rd step, the thick liquid matter that second step is obtained adds at least one in a small amount of ethanol, Oleum Sesami, acetic acid, and fully stirring and evenly mixing becomes paste.
For solving the problems of the technologies described above, the present invention also provides above-mentioned Chinese medicine composition in the application for the preparation of in treatment beriberi.
Beneficial effect of the present invention:
With respect to the medicine that is used for the treatment of beriberi of the prior art, adopt this Chinese medicine composition to have treating beri-beri evident in efficacy, cure rate is high, is difficult for the advantages such as recurrence.
The specific embodiment
The invention provides a kind of like this Chinese medicine composition that is used for the treatment of beriberi, it comprises: Radix Achyranthis, Radix Sophorae Flavescentis, Radix Scutellariae, Fructus Cnidii, Herba Taraxaci, Radix Bupleuri, Radix Ophiopogonis, Folium Isatidis, the Rhizoma Atractylodis Macrocephalae, Herba Houttuyniae, Radix Scrophulariae, Radix Puerariae, Rhizoma Gastrodiae, Radix Glycyrrhizae, Fructus Arctii, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Rhizoma Polygoni Cuspidati, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Radix Notoginseng, Radix Dichroae, Herba Artemisiae Annuae, the Radix Astragali, Radix Gentianae, Semen Coicis, Semen Arecae.
Radix Achyranthis: bitter in the mouth acid, flat, enter the heart, liver, large intestine three warps.Effect promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatism husband's arthralgia, beriberi, edema, dysentery, malaria, diphtheria, carbuncle, traumatic injury.
Radix Sophorae Flavescentis: bitter in the mouth; Cold in nature.Cure mainly heat clearing and damp drying; Wind dispelling insecticide; Discharging fresh blood stool; Jaundice; Dysuria; Edema; Leukorrhagia; Pudendal pruritus; Scabies; Leprosy; Skin pruritus; Noxious dampness skin infection.
Radix Scutellariae: bitter in the mouth, cold in nature, enter the heart, lung, stomach, gallbladder, large intestine channel, there is heat clearing and damp drying, eliminating fire and detoxication, antiabortive, the effect of hemostasis, is mainly used in diarrhoea, dysentery, jaundice, pyretic stranguria due to damp and hot; Cough due to lung-heat, thirsty pharyngalgia, also can be used for excessive fetal movement due to heat in pregnancy, and pyretic toxicity pathogenic fire is invaded the swollen card of carbuncle sore poison of excessive skin.That Radix Scutellariae has is antipyretic, calm, blood pressure lowering, diuresis, reduction capillary permeability, suppress the effects such as intestinal tube wriggling, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, Bacillus typhi, dysentery coccus, newcastle, bacillus pyocyaneus are had to certain inhibitory action, upper respiratory tract infection, chronic bronchitis, bacillary dysentery etc. are had to good curative effect.
Fructus Cnidii: warm in nature, acrid in the mouth, hardship; Cure mainly warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Rhizoma Chuanxiong. acrid in the mouth, temperature, returns liver, gallbladder, pericardium channel.Cure mainly blood-activating and qi-promoting, wind-expelling pain-stopping.
Herba Taraxaci: sweet in the mouth, micro-hardship, cold, cure mainly upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder is assisted inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.
Radix Bupleuri: meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, gallbladder meridian, expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, is mainly used in cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, be slightly cold, GUIXIN, lung, stomach warp, have YIN nourishing and the production of body fluid promoting, and the effect that lung moistening clears away heart-fire is mainly used in dryness of the lung dry cough, and deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Folium Isatidis: bitter in the mouth, cold.Return liver, the heart, stomach warp.Tool heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis.Main epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, cold in nature, enter liver, gallbladder meridian, there is heat clearing and damp drying, fall the effect of letting out liver-fire and function of gallbladder promoting, the breast side of body being mainly used in due to dampness-heat of the liver is had a pain, bitter taste deafness, conjunctival congestion and swelling pain; Jaundice due to damp-heat; The dizzy order of flaming up of liver-fire is swollen; The high heat of liver-fire wind-transformation is through taking out; The card such as leucorrhea, dysuria of damp invasion of lower energizer
Herba Houttuyniae: cold nature, bitter in the mouth, returns lung meridian, bladder, large intestine channel, has heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; The effect of inducing diuresis for treating stranguria syndrome, is mainly used in lung abscess vomiting pus; Expectorant dyspnea of heat type is coughed; Throat; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria.
Radix Scrophulariae: sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel, has clearing away heat and cooling blood, eliminating fire and detoxication, the effect of YIN nourishing, is mainly used in pathogenic warmth and joins the army, the pericardium that caves in, maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin.
Radix Puerariae: sweet in the mouth, pungent, cool in nature, enter spleen, stomach warp, there is inspiration gastric qi, clearing away heat and promoting production of body fluid, expelling pathogenic factors from muscles is delivered, raw positive, oozes the effect of rash, is mainly used in fever caused by exogenous pathogens, headache, stiff nape and back, calentura is thirsty, quenches one's thirst; Diarrhea due to hypofunction of the spleen, the cards such as clear YANG failing to ascend, intrinsic heat during the light clear expelling heat from the exterior of Radix Puerariae is wet.
Rhizoma Gastrodiae: sweet in the mouth, property is flat, enters Liver Channel, has suppressing the hyperactive liver to relieve the wind syndrome, spasmolytic, the effect of removing obstruction in the collateral to relieve pain, is mainly used in the dizziness and headache of flaming up of liver-fire; Convulsion with spasms due to excessive rising of liver-YANG, liver-wind stirring up internally or wind-phlegm are jammed, the cards such as epilepsy, also for rheumatic arthralgia, articular instability, the meciless card that waits of numb limbs and tense tendons, Rhizoma Gastrodiae has the effect of enhancing body non-specific immunity and cellular immunization, humoral immunization.
Radix Glycyrrhizae: sweet in the mouth, property is flat, enters 12 warps, has heat-clearing and toxic substances removing, is in harmonious proportion the property of medicine, the effect of expelling phlegm for arresting cough, and can spleen invigorating and in, relieving spasm to stop pain, is mainly used in the abdominal distension and anorexia of weakness of the spleen and stomach, weak; Can alleviate contracture pain in abdomen, relax the strong and toxicity of some drugs, alleviate the toxic and side effects of medicine to body or gastrointestinal is stimulated, by adding Radix Glycyrrhizae can play QI invigorating neutralization, be in harmonious proportion the effect of each component.
Fructus Arctii: mildly bitter flavor, cold nature, return liver, gallbladder, lung meridian, there is the effect of expelling wind and removing dampness, dissipating blood stasis analgesic therapy, preventing phlegm from forming and stopping coughing, for arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.Fructus Arctii has and suppresses and killing action staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, micrococcus catarrhalis, newcastle, Bacillus proteus, bacillus pyocyaneus etc.
Radix Arnebiae (Radix Lithospermi): nature and flavor: cold in nature, sweet in the mouth, salty, GUIXIN, Liver Channel, be mainly used in that heat in blood poison is contained, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire etc.
Flos Lonicerae: sweet in the mouth, cold in nature, enter the heart, lung, stomach, large intestine channel, there is the effect of heat-clearing and toxic substances removing, holding concurrently can eliminating pathogenic heat from blood to cure dysentery.Be mainly used in affection due to external wind and heat, epidemic febrile disease pyretic toxicity is contained, or epidemic febrile disease is from the beginning of pathogenic heat still at the part of the body cavity above the diaphragm housing the heart and lungs and when not descending; Pyretic toxicity dysentery, stool hematochezia; Fever disease in summer card; The carbuncle sore that pyretic toxicity gathers is from the beginning of, inflammation heat person of swelling and ache etc., Flos Lonicerae has good antipyretic effect, energy antiinflammatory, what control inflammation oozes out and inflammatory hyperplasia, can promote leukocytic phagocytic function, multiple pyococcus and pathogenic entero becteria are had to stronger bacteriostasis, comprise staphylococcus, Hemolytic streptococcus, meningococcus, dysentery bacterium, Bacillus typhi, newcastle, bacillus pyocyaneus, tubercule bacillus etc.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature, return liver, gallbladder, lung meridian, there is the effect of expelling wind and removing dampness, dissipating blood stasis analgesic therapy, preventing phlegm from forming and stopping coughing, for arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.Rhizoma Polygoni Cuspidati has and suppresses and killing action staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, micrococcus catarrhalis, newcastle, Bacillus proteus, bacillus pyocyaneus etc.
Rhizoma Osmundae: acrid in the mouth, hardship, cold.Return lung meridian.Tool heat-clearing and toxic substances removing, cooling blood for hemostasis, the function of parasite killing.Cure mainly seasonal pathogen sense, partial heat person, heating is heavy, aversion to cold is light, it is red to have a headache, swallow, pharyngeal swelling, xerostomia and thirsty, red tongue, white and thin fur, floating pulse.
Fructus Mume: sour in the mouth, puckery, flat, enter liver, spleen, lung, large intestine channel, to astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, and the effect of relieving colic caused by ascaris, is mainly used in chronic cough of deficiency lung; Deficiency-heat excessive thirst; Chronic malaria; Chronic diarrhea; Dysentery; Have blood in stool; Hematuria; Metrorrhagia; Ascariasis of biliary tract stomachache; Vomiting; The cards such as ancylostomiasis
Fructus Forsythiae: bitter in the mouth, be slightly cold, enter the heart, lung, small intestine meridian, there is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effect of dispelling wind and heat pathogens.Be mainly used in warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction, the diseases such as clearing away heart-fire.
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature, enter liver, stomach warp, there is hemostasia and dissipation blood stasis, the effect of reducing swelling and alleviating pain, be mainly used in hemoptysis, metrorrhagia etc. various go out blood disorder, blood vessel dilating, reduce blood pressure, improve microcirculation, increase blood flow, prevention and treatment heart and brain tissues ischemia, anoxia; Promote protein, ribonucleic acid (RNA), DNA (deoxyribonucleic acid) (DNA) to synthesize, building body; Promote blood cell metabolism, balance adjustment blood cell; Two-ways regulation nervus centralis, improves mentally, strengthens learning and memory ability; Hemostasis, blood circulation promoting and blood stasis dispelling; Protect the liver, antiinflammatory.
Radix Dichroae: acrid in the mouth; Cold; Bitter; Poisonous, enter lung, the heart, Liver Channel, treat phlegm retention in the heart; Effect of malaria.
Herba Artemisiae Annuae: bitter in the mouth, pungent, cold.Return liver, gallbladder meridian, three warmers, kidney channel.The clear deficiency-heat thoroughly of tool, removing heat from blood, except steaming, removes and steams, the effect of preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.
The Radix Astragali: sweet in the mouth, warm in nature, enter spleen, lung meridian, there is tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effects such as holder skin ulcer granulation promoting, are mainly used in the weak anorexia and loose stool due to deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had to inhibitory action.The Radix Astragali can appreciable impact splenocyte Information Conduction, realizes immunoregulation effect.
Radix Gentianae: bitter in the mouth, cold in nature, enter liver, gallbladder meridian, there is heat clearing and damp drying, fall the effect of letting out liver-fire and function of gallbladder promoting, the breast side of body being mainly used in due to dampness-heat of the liver is had a pain, bitter taste deafness, conjunctival congestion and swelling pain; Jaundice due to damp-heat; The dizzy order of flaming up of liver-fire is swollen; The high heat of liver-fire wind-transformation is through taking out; The card such as leucorrhea, dysuria of damp invasion of lower energizer.
Semen Coicis: cool in nature, sweet in the mouth, light, returns spleen, stomach, lung meridian.There is the function of spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic, for weakness of the spleen and stomach, loose stool diarrhoea, or vaginal discharge diseases of women, insufficiency of the spleen leading to overabundance of dampness edema, dysuria, or beriberi swells and ache; Damp and hot arthralgia pain, contracture of the limbs, miserable pain; Lung abscess cough and spit purulent sputum, or enterodynia contracture stomachache.
Semen Arecae: bitter in the mouth, pungent, puckery, property is wet, nontoxic, cures mainly rapid digestion of food and relieves oedema or abdominal distension through diuresis or purgation, and kills Enterozoa, volt corpse, proglottid of tapeworm; Except dampness, get round by bribery, sharp ball key, relieving restlessness, caking in broken abdomen; Also can control beriberi, edema, chest pain, dysentery, abdominal distention stomachache, defecation can not, mental disorder dyspnea with rapid respiration, treat pernicious malaria, resist communicable subtropical diseases.
Chinese medicine composition of the present invention is still not clear the application mechanism for the treatment of beriberi, may be by the comprehensive function performance drug effect of antibacterial, antipruritic, the heat clearing away of medicine, dehumidifying, blood circulation promoting and blood stasis dispelling, dredging the meridian etc., control pruritus to reach, clear away the dampness and heat, reach the object of radical cure.
In the described Chinese medicine composition that is used for the treatment of beriberi, the ratio of weight and number of various components can be preferably: Radix Achyranthis 22～28 weight portions, Radix Sophorae Flavescentis 12-18 weight portion, Radix Scutellariae 16～20 weight portions, Fructus Cnidii 4～6 weight portions, Herba Taraxaci 10～12 weight portions, Radix Bupleuri 10-15 weight portion, Radix Ophiopogonis 6～10 weight portion, Folium Isatidis 4～6 weight portions, Rhizoma Atractylodis Macrocephalae 10-15 weight portion, Herba Houttuyniae 10～12 weight portions, Radix Scrophulariae 15-20 weight portion, Radix Puerariae 20～25 weight portions, Rhizoma Gastrodiae 10-12 weight portion, Radix Glycyrrhizae 15～20 weight portions, Fructus Arctii 10～15 weight portions, Radix Arnebiae (Radix Lithospermi) 10-12 weight portion, Flos Lonicerae 3～10 weight portions, Rhizoma Polygoni Cuspidati 10-12 weight portion, Rhizoma Osmundae 10～12 weight portions, Fructus Mume 4～6 weight portions, Fructus Forsythiae 10～15 weight portions, Radix Notoginseng 10-12 weight portion, Radix Dichroae 10-12 weight portion, Herba Artemisiae Annuae 5-10 weight portion, Radix Astragali 5-8 weight portion, Radix Gentianae 6～10 weight portions, Semen Coicis 10-15 weight portion, Semen Arecae 20～50 weight portions.
In the described Chinese medicine composition that is used for the treatment of animal beriberi, the ratio of weight and number of various components also can be more preferably: Radix Achyranthis 25～28 weight portions, Radix Sophorae Flavescentis 12-15 weight portion, Radix Scutellariae 16～20 weight portions, Fructus Cnidii 4～5 weight portions, Herba Taraxaci 10～12 weight portions, Radix Bupleuri 10-15 weight portion, Radix Ophiopogonis 6～8 weight portion, Folium Isatidis 4～6 weight portions, Rhizoma Atractylodis Macrocephalae 10-12 weight portion, Herba Houttuyniae 10～12 weight portions, Radix Scrophulariae 15-20 weight portion, Radix Puerariae 20～25 weight portions, Rhizoma Gastrodiae 10-12 weight portion, Radix Glycyrrhizae 15～20 weight portions, Fructus Arctii 10～12 weight portions, Radix Arnebiae (Radix Lithospermi) 10-12 weight portion, Flos Lonicerae 3～5 weight portions, Rhizoma Polygoni Cuspidati 10-12 weight portion, Rhizoma Osmundae 10～12 weight portions, Fructus Mume 4～6 weight portions, Fructus Forsythiae 10～12 weight portions, Radix Notoginseng 10-12 weight portion, Radix Dichroae 10-11 weight portion, Herba Artemisiae Annuae 5-10 weight portion, Radix Astragali 5-8 weight portion, Radix Gentianae 6～10 weight portions, Semen Coicis 10-15 weight portion, Semen Arecae 20～30 weight portions.
The present invention also provides the preparation method of the above-mentioned Chinese medicine composition that is used for the treatment of beriberi, and it comprises:
The first step, mixes each component pulverize in described ratio;
Second step, the mixture after the pulverizing that the first step is obtained adds and in ethanol, soaks and decoct, and merging decoction liquor, filters and is concentrated into thick shape; Gained thick liquid can directly use, optional, can carry out the 3rd step processing;
The 3rd step, the thick liquid matter that second step is obtained adds at least one in a small amount of ethanol, Oleum Sesami, acetic acid, and fully stirring and evenly mixing becomes paste.
Wherein, the ratio of ethanol, Oleum Sesami, acetic acid can regulate arbitrarily, above-mentioned substance except adjusting viscosity, the effect that can also play antiinflammatory, sterilization of ethanol, acetic acid.
External application Chinese medicine composition of medicine dosage form in the present invention is unguentum.
The present invention also provides the application of a kind of external medicine composition in the medicine for the preparation for the treatment of beriberi.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
The preparation of embodiment 1 Chinese medicine composition 1
By Radix Achyranthis 20g, Radix Sophorae Flavescentis 10g, Radix Scutellariae 15g, Fructus Cnidii 2g, Herba Taraxaci 10g, 4g, Folium Isatidis 4g, Rhizoma Atractylodis Macrocephalae 10g, Herba Houttuyniae 10g, Radix Scrophulariae 10g, Radix Puerariae 20g, Rhizoma Gastrodiae 10g, Radix Glycyrrhizae 15g, Fructus Arctii 10g, Radix Arnebiae (Radix Lithospermi) 10g, Flos Lonicerae 1g, Rhizoma Polygoni Cuspidati 10g, Rhizoma Osmundae 10g, Fructus Mume 4g, Fructus Forsythiae 10g, Radix Notoginseng 10g, Radix Dichroae 10g, Herba Artemisiae Annuae 1g, Radix Astragali 5g, Radix Gentianae 5g, Semen Coicis 10g, Semen Arecae 10g mixed and pulverized Radix Bupleuri 10g, Radix Ophiopogonis; Mixture after pulverizing is added in 2000ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor and filter and be concentrated into thick shape; Add subsequently a small amount of ethanol, furnishing paste.
The preparation of embodiment 2 Chinese medicine compositions 2
By Radix Achyranthis 30g, Radix Sophorae Flavescentis 20g, Radix Scutellariae 20g, Fructus Cnidii 6g, Herba Taraxaci 15g, 10g, Folium Isatidis 6g, Rhizoma Atractylodis Macrocephalae 15g, Herba Houttuyniae 15g, Radix Scrophulariae 20g, Radix Puerariae 30g, Rhizoma Gastrodiae 15g, Radix Glycyrrhizae 20g, Fructus Arctii 20g, Radix Arnebiae (Radix Lithospermi) 15g, Flos Lonicerae 10g, Rhizoma Polygoni Cuspidati 20g, Rhizoma Osmundae 12g, Fructus Mume 6g, Fructus Forsythiae 20g, Radix Notoginseng 15g, Radix Dichroae 15g, Herba Artemisiae Annuae 10g, Radix Astragali 10g, Radix Gentianae 10g, Semen Coicis 15g, Semen Arecae 50g mixed and pulverized Radix Bupleuri 20g, Radix Ophiopogonis; Mixture after pulverizing is added in 2500ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor and filter and be concentrated into thick shape; Add subsequently a small amount of ethanol and acetic acid (volume ratio 1:1), furnishing paste.
The preparation of embodiment 3 Chinese medicine compositions 3
By Radix Achyranthis 22g, Radix Sophorae Flavescentis 12g, Radix Scutellariae 16g, Fructus Cnidii 4g, Herba Taraxaci 10g, 6g, Folium Isatidis 4g, Rhizoma Atractylodis Macrocephalae 10g, Herba Houttuyniae 10g, Radix Scrophulariae 15g, Radix Puerariae 20g, Rhizoma Gastrodiae 10g, Radix Glycyrrhizae 15g, Fructus Arctii 10g, Radix Arnebiae (Radix Lithospermi) 10g, Flos Lonicerae 3g, Rhizoma Polygoni Cuspidati 10g, Rhizoma Osmundae 10g, Fructus Mume 4g, Fructus Forsythiae 10g, Radix Notoginseng 10g, Radix Dichroae 10g, Herba Artemisiae Annuae 5g, Radix Astragali 5g, Radix Gentianae 6g, Semen Coicis 10g, Semen Arecae 20g mixed and pulverized Radix Bupleuri 10g, Radix Ophiopogonis; Mixture after pulverizing is added in 2000ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor and filter and be concentrated into thick shape; Add subsequently a small amount of ethanol and Oleum Sesami (volume ratio 1:1), furnishing paste.
The preparation of embodiment 4 Chinese medicine compositions 4
By Radix Achyranthis 28g, Radix Sophorae Flavescentis 18g, Radix Scutellariae 20g, Fructus Cnidii 6g, Herba Taraxaci 12g, 10g, Folium Isatidis 6g, Rhizoma Atractylodis Macrocephalae 15g, Herba Houttuyniae 12g, Radix Scrophulariae 20g, Radix Puerariae 25g, Rhizoma Gastrodiae 12g, Radix Glycyrrhizae 20g, Fructus Arctii 15g, Radix Arnebiae (Radix Lithospermi) 12g, Flos Lonicerae 10g, Rhizoma Polygoni Cuspidati 12g, Rhizoma Osmundae 12g, Fructus Mume 6g, Fructus Forsythiae 15g, Radix Notoginseng 12g, Radix Dichroae 12g, Herba Artemisiae Annuae 10g, Radix Astragali 8g, Radix Gentianae 10g, Semen Coicis 15g, Semen Arecae 50g mixed and pulverized Radix Bupleuri 15g, Radix Ophiopogonis; Mixture after pulverizing is added in 2500ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor and filter and be concentrated into thick shape; Add subsequently a small amount of Oleum Sesami, furnishing paste.
The preparation of embodiment 5 Chinese medicine compositions 5
By Radix Achyranthis 25g, Radix Sophorae Flavescentis 12g, Radix Scutellariae 16g, Fructus Cnidii 4g, Herba Taraxaci 10g, 6g, Folium Isatidis 4g, Rhizoma Atractylodis Macrocephalae 10g, Herba Houttuyniae 10g, Radix Scrophulariae 15g, Radix Puerariae 20g, Rhizoma Gastrodiae 10g, Radix Glycyrrhizae 15g, Fructus Arctii 10g, Radix Arnebiae (Radix Lithospermi) 10g, Flos Lonicerae 3g, Rhizoma Polygoni Cuspidati 10g, Rhizoma Osmundae 10g, Fructus Mume 4g, Fructus Forsythiae 10g, Radix Notoginseng 10g, Radix Dichroae 10g, Herba Artemisiae Annuae 5g, Radix Astragali 5g, Radix Gentianae 6g, Semen Coicis 10g, Semen Arecae 20g mixed and pulverized Radix Bupleuri 10g, Radix Ophiopogonis; Mixture after pulverizing is added in 2000ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor and filter and be concentrated into thick shape; Add subsequently a small amount of ethanol, acetic acid and Oleum Sesami (volume ratio 1:1:1), furnishing paste.
The preparation of embodiment 6 Chinese medicine compositions 6
By Radix Achyranthis 28g, Radix Sophorae Flavescentis 15g, Radix Scutellariae 20g, Fructus Cnidii 5g, Herba Taraxaci 12g, 8g, Folium Isatidis 6g, Rhizoma Atractylodis Macrocephalae 12g, Herba Houttuyniae 12g, Radix Scrophulariae 20g, Radix Puerariae 25g, Rhizoma Gastrodiae 12g, Radix Glycyrrhizae 20g, Fructus Arctii 12g, Radix Arnebiae (Radix Lithospermi) 12g, Flos Lonicerae 5g, Rhizoma Polygoni Cuspidati 12g, Rhizoma Osmundae 12g, Fructus Mume 6g, Fructus Forsythiae 12g, Radix Notoginseng 12g, Radix Dichroae 11g, Herba Artemisiae Annuae 10g, Radix Astragali 8g, Radix Gentianae 10g, Semen Coicis 15g, Semen Arecae 30g mixed and pulverized Radix Bupleuri 15g, Radix Ophiopogonis; Mixture after pulverizing is added in 2000ml ethanol and soaked 40 minutes, and decoct 2 times, decoct 1 hour at every turn, merge decoction liquor, filter and be concentrated into thick shape; Add subsequently a small amount of Oleum Sesami and acetic acid (volume ratio 1:1), furnishing paste.
Clinical experiment
For example: beriberi case 69 examples, wherein male's 49 examples, women's 20 examples, age 12-68 year, erosive type 38 examples, vesicle 15 examples, keratinization type 16 examples, patients with mild 10 examples, moderate patient's 41 examples, severe patient's 18 examples, use paste application of the present invention affected part, repeatedly rub, twice of every day, after 3 days, 69 all occurring being clearly better, (symptom does not disappear completely, but it is normal that skin has recovered substantially, cast off a skin and obviously reduce, the degree of scratching where it itches and number of times all reduce or alleviate), within 10 days, cure afterwards (symptom disappears completely) 42 examples, within 15 days, cure and amount up to 68 examples afterwards, after three months, follow up a case by regular visits to, amount to 4 people's recurrences, after half a year, follow up a case by regular visits to and amount to 5 people's recurrences.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the restriction of the present invention being made to other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (4)
1. a Chinese medicine composition that is used for the treatment of beriberi, is characterized in that, compositions is by Radix Achyranthis, Radix Sophorae Flavescentis, Radix Scutellariae, Fructus Cnidii, Herba Taraxaci, Radix Bupleuri, Radix Ophiopogonis, Folium Isatidis, the Rhizoma Atractylodis Macrocephalae, Herba Houttuyniae, Radix Scrophulariae, Radix Puerariae, Rhizoma Gastrodiae, Radix Glycyrrhizae, Fructus Arctii, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Rhizoma Polygoni Cuspidati, Rhizoma Osmundae, Fructus Mume, Fructus Forsythiae, Radix Notoginseng, Radix Dichroae, Herba Artemisiae Annuae, the Radix Astragali, Radix Gentianae, Semen Coicis, Semen Arecae is made, wherein, and Radix Achyranthis 20～30 weight portions, Radix Sophorae Flavescentis 10～20 weight portions, Radix Scutellariae 15～20 weight portions, Fructus Cnidii 2～6 weight portions, Herba Taraxaci 10～15 weight portions, Radix Bupleuri 10～20 weight portions, Radix Ophiopogonis 4～10 weight portion, Folium Isatidis 4～6 weight portions, the Rhizoma Atractylodis Macrocephalae 10～15 weight portions, Herba Houttuyniae 10～15 weight portions, Radix Scrophulariae 10～20 weight portions, Radix Puerariae 20～30 weight portions, Rhizoma Gastrodiae 10～15 weight portions, Radix Glycyrrhizae 15～20 weight portions, Fructus Arctii 10～20 weight portions, Radix Arnebiae (Radix Lithospermi) 10～15 weight portions, Flos Lonicerae 1～10 weight portion, Rhizoma Polygoni Cuspidati 10-20 weight portion, Rhizoma Osmundae 10～12 weight portions, Fructus Mume 4～6 weight portions, Fructus Forsythiae 10～20 weight portions, Radix Notoginseng 10～15 weight portions, Radix Dichroae 10～15 weight portions, Herba Artemisiae Annuae 1～10 weight portion, the Radix Astragali 5～10 weight portions, Radix Gentianae 5～10 weight portions, Semen Coicis 10～15 weight portions, Semen Arecae 10～50 weight portions, described Chinese medicine composition is prepared from by the following method:
The first step, mixes each component pulverize in described ratio;
Second step, the mixture after the pulverizing that the first step is obtained adds and in ethanol, soaks and decoct, and merging decoction liquor, filters and is concentrated into thick shape; Gained thick liquid directly uses,
The 3rd step, the thick liquid matter that second step is obtained adds at least one in a small amount of ethanol, Oleum Sesami, acetic acid, and fully stirring and evenly mixing becomes paste.
2. Chinese medicine composition as claimed in claim 1, is characterized in that: described Chinese medicine composition dosage form is unguentum.
3. the preparation method of the Chinese medicine composition described in claim 1 to 2 any one, is characterized in that, preparation method is:
The first step, mixes each component pulverize in described ratio;
Second step, the mixture after the pulverizing that the first step is obtained adds and in ethanol, soaks and decoct, and merging decoction liquor, filters and is concentrated into thick shape; Gained thick liquid directly uses;
The 3rd step, the thick liquid matter that second step is obtained adds at least one in a small amount of ethanol, Oleum Sesami, acetic acid, and fully stirring and evenly mixing becomes paste.
4. the application of the Chinese medicine composition described in claim 1 to 2 any one in the medicine for the preparation for the treatment of beriberi.
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| CN103751611A (en) * | 2014-01-16 | 2014-04-30 | 王雅冬 | Compound traditional Chinese medicine for treating tinea corporis |
| CN104147451A (en) * | 2014-07-14 | 2014-11-19 | 卞佳林 | Pharmaceutical composition for treating tinea corporis as well as preparation method and application thereof |
| CN105663429A (en) * | 2016-02-17 | 2016-06-15 | 蒋玉群 | Medicine for treating vesicular beriberi |
| CN105853961A (en) * | 2016-04-17 | 2016-08-17 | 姜凤霞 | Traditional Chinese medicine composition for treating dermatophytosis |
| CN106266306A (en) * | 2016-08-31 | 2017-01-04 | 李海峰 | The Chinese medicine composition for the treatment of tinea pedis |
| CN106214873A (en) * | 2016-08-31 | 2016-12-14 | 李海峰 | Traditional Chinese medicine gel cream note for the treatment of tinea pedis and preparation method thereof |
| CN106511934A (en) * | 2016-11-30 | 2017-03-22 | 王克荣 | Traditional Chinese medicine for treating hygropyretic beriberi |
| CN107510803A (en) * | 2017-09-01 | 2017-12-26 | 广西叶茂生物科技有限公司 | A kind of tinea pedis cleaning fluid |
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| CN101411769A (en) * | 2008-11-26 | 2009-04-22 | 孙素芬 | Medicament for treating beriberi and preparation method thereof |
| CN102357146A (en) * | 2011-10-31 | 2012-02-22 | 王广月 | Traditional Chinese medicine for treating beriberi |
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| CN101411769A (en) * | 2008-11-26 | 2009-04-22 | 孙素芬 | Medicament for treating beriberi and preparation method thereof |
| CN102357146A (en) * | 2011-10-31 | 2012-02-22 | 王广月 | Traditional Chinese medicine for treating beriberi |
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