CN106256371A - 一种治疗血瘀型癥瘕的中药组合物及其制备方法 - Google Patents

一种治疗血瘀型癥瘕的中药组合物及其制备方法 Download PDF

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CN106256371A
CN106256371A CN201610813316.1A CN201610813316A CN106256371A CN 106256371 A CN106256371 A CN 106256371A CN 201610813316 A CN201610813316 A CN 201610813316A CN 106256371 A CN106256371 A CN 106256371A
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Abstract

一种治疗血瘀型癥瘕的中药组合物及其制备方法。本发明属于中药制剂领域,目的是根据中医对血瘀型癥瘕的认识机理而提供的一种治疗血瘀型癥瘕的中药组合物,所述中药组合物的各个组分及其质量份比如下:三七、凌霄花、醋穿山甲、鹿角、赤芍、苏木、瓦楞子、刘寄奴、牡丹皮、郁金、素馨花、山楂、木香、鸡内金、五爪龙、黑老虎、千斤拔、茜草、飞来参、甘草;本发明提供的药物是一个很好的中药组方。

Description

一种治疗血瘀型癥瘕的中药组合物及其制备方法
技术领域
[0001] 本发明属于中药制剂领域,具体涉及一种治疗血瘀型癥瘕的中药组合物,特别是供血瘀型癥瘕患者使用的中药组合物及其制备方法的领域。背景技术
[0002] 据医学文献显示:妇女的癥瘕一症,它包括了现代医学中的妇科的各种良性肿瘤, 是妇科常见病之一。本病多因产后恶露不尽,房事不节,余血未尽,或外邪侵袭,凝滞气血, 情志抑郁,饮食内伤,或忧思伤脾,脏腑失调,气滞血瘀,气机不畅,气滞则血瘀,瘀血内结聚而为块,故症见:小腹有包块,积块坚硬,固定不移,疼痛拒按,肌肤少泽,干不欲饮,月经延后或淋漓不断,面色晦黯,舌紫黯,苔厚而干,脉沉涩有力,尿频、尿急、排尿困难、尿潴留、便秘。妇科检查,B超检查协助可确诊为:子宫肿瘤、囊肿、卵巢肿瘤、盆腔炎性包块、结核性包块等;良性肿瘤生长慢,病程长。良性肿瘤症瘕,病在血者以胀痛为主,症块坚硬,固定不移。
[0003] 就目前而言,现代医学还没有很好的办法来治疗妇女血瘀型癥瘕,主要用手术治疗之,只能治标不能治本,不能有效的根治妇女血瘀型癥瘕,效果不理想,给病人带来刀术之苦和经济上的困难以及精神上的压力。中医多用“桂枝茯苓丸”《金贵要略》或少腹逐瘀汤 《医林改错》,具有疗效慢,治愈率低的缺点。
[0004] 那么,就如何找到一种可有效治疗上述血瘀型癥瘕的中药组合物,是我们目前急需要解决的问题。发明内容
[0005] 随着我国中医中药学的不断发展,在治疗血瘀型癥瘕上,人们逐渐意识到了中医治疗慢性盆腔炎的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗血瘀型癥瘕的现状,本发明的目的是在于提供一种治疗血瘀型癥瘕的中药组合物, 以解决血瘀型癥瘕患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗血瘀型癥瘕。
[0006] 为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗血瘀型癥瘕的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示。[〇〇〇7] 三七3〜10g、凌霄花3〜6g、醋穿山甲5〜10g、鹿角5〜10g、赤苟6〜12g、苏木3〜 1(^、瓦愣子3〜168、刘寄奴5〜128、牡丹皮6〜1(^、郁金8〜168、素馨花5〜128、山楂3〜 12g、木香3〜12g、鸡内金3〜12g、五爪龙30〜60g、黑老虎9〜16g、千斤拔15〜30g、茜草10〜 16区、飞来参50〜9(^、甘草2〜1(^。
[0008] —种治疗血瘀型癥瘕的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:三七4〜9g、凌霄花4〜5.5g、醋穿山甲6〜9g、鹿角6〜9g、赤苟7〜llg、苏木4〜9g、瓦愣子4〜14g、刘寄奴6〜llg、牡丹皮7〜9g、郁金10〜14g、素馨花6〜llg、山楂4〜llg、木香4〜llg、鸡内金4〜llg、五爪龙35〜50g、黑老虎10〜14g、千斤拔18〜26g、茜草11〜14g、飞来参 60〜80g、甘草3〜9g。
[0009] —种治疗血瘀型癥瘕的中药组合物及其制备方法,其特征在于,所述“最佳方案” 的中药组合物的各个组分及其质量份比如下所示:三七8g、凌霄花5g、醋穿山甲8g、鹿角8g、赤芍10g、苏木8g、瓦楞子12g、刘寄奴10g、牡丹皮8g、郁金12g、素馨花10g、山楂10g、木香10g、鸡内金10g、五爪龙42g、黑老虎12g、千斤拔 23g、茜草12g、飞来参70g、甘草8g。
[0010] —种治疗血瘀型癥瘕的中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:A、 除三七、鹿角、鸡内金、醋穿山甲(研磨成药粉)外,将上述其它原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;B、 将包好的原料中药放入冷开水中浸泡一小时,然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内,注入过药36mm的冷开水进行第一次煎煮45分钟,滤取药液后,再次注入过药32mm的微温开水进行第二次煎煮35分钟,二次混合浓缩成50%的中药液400毫升备用。
[0011] —种治疗血瘀型癥瘕的中药组合物及其制备方法,其特征在于,所述服用方法为: 将制备好的中药液以一天服用,每日一剂,早晚各服一次,给药量200毫升/次,饭前一小时趁温和三七、鹿角、鸡内金和醋穿山甲药粉兑服,6天为一个疗程,1〜3个疗程即可痊愈。
[0012] 本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:三七,性味:味甘、微苦、性湿,具有止血、散血、定痛之功效,用于治疗跌扑瘀肿、胸痹绞痛、癥瘕、血瘀经闭、痛经、产后瘀阴腹痛、疮痈肿痛等症;凌霄花,性味:味酸、性微寒,具有清热凉血、化瘀散结、祛风止痒之功效,用于治疗血滞经闭、痛经、症瘕、崩中漏下、血热风痒、疮疥陷疹、酒齄鼻等症;醋穿山甲,性味:咸、微寒,具有通经下乳、消肿排浓、搜风活络之功效,用于治疗闭经癥瘕、乳汁不通、痈肿疮毒、关节痹痛、麻木拘挛;鹿角,性味:味咸、性温,具有补肾阳、益精血、强筋骨、行血消肿之功效,用于治疗肾虚腰脊冷痛、阳痿遗精、崩漏、白带、尿频尿多、阴疽疮疡、乳痈肿痛、跌打瘀肿、筋骨疼痛等症; 赤芍,性味:微寒,具有清热凉血、活血祛瘀之功效,用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤等症;苏木,性味:甘、咸、平、无毒,具有活血祛瘀、消肿定痛之功效,用于治疗妇人血滞经闭、 痛经、产后瘀阻心腹痛、产后血晕、痈肿、跌打损伤、破伤风等症;瓦楞子,性味:味甘、咸、性平,具有消痰化瘀、软坚散结、制酸止痛之功效,用于治疗瘰疬、癭瘤、癥瘕痞块、顽痰久咳、胃痛吐酸、牙疳、外伤出血、冻疮及烫火伤等症;刘寄奴,性味:味辛、微苦、性温,具有破瘀通经、止血消肿、消食化积之功效,用于治疗经闭、痛经、产后瘀滞腹痛、恶露不尽、癥瘕、跌打损伤、金疮出血、风湿痹痛、便血、尿血、痈疮肿毒、烫伤、食积腹痛、泄泻痢疾等症;牡丹皮,性味:辛苦、凉、微寒,具有清热、活血散瘀之功效,用于治疗温热病热入血分、 发斑、吐衄、热泪盈眶病菌后期热伏阴分发热、阴虚骨蒸潮热、血滞经闭、痛经、痈肿疮毒、跌扑伤痛、风湿热痹等症;郁金,性味:味辛、苦、性寒,具有活血止痛、行气解郁、清心凉血、疏肝利胆之功效,用于治疗胸腹胁肋诸痛、妇女痛经、经闭、症瘕结块、热病神昏、癫狂、惊痫、吐血、衄备、血淋、砂淋、黄追等症;素馨花,性味:微苦、性平、具有舒肝解郁、行气止痛之功效,用于治疗肝郁气滞所致的胁肋脘腹作痛、下痢腹痛等症;山楂,性味:酸甘、微温,无毒,具有消食积、化滞瘀之功效,用于治疗饮食积滞、脘腹胀痛、泄泻痢疾、血瘀痛经、闭经、产后腹痛、恶露不尽等症;木香,性味:辛味辛、苦、性温,具有行气止痛、调中导滞之功效,用于治疗胞胁胀满足、 脘腹胀痛、哎吐泄泻、痢疾后重等症;鸡内金,性味:味甘、性平,具有健脾消食、涩精止遗、消癥化石之功效,用于治疗消化不良、饮食积滞、呕吐反胃、泄泻下痢、小儿疳积、遗精、遗尿、小便频数、泌尿系结石及胆结石、 癥瘕经闭、喉痹乳蛾、牙疳口疮等症;五爪龙,性味:甘、微苦、性平,具有祛风除湿、祛瘀消肿之功效,用于治疗风湿痿痹、腰腿痛、痢疾、水肿、带下、瘰疬、跌打损伤、经闭、乳少等症;黑老虎,性味:辛、微苦、性温,具有行气止痛、散瘀通络之功效,用于治疗胃及十二指肠溃疡、慢性胃炎、急性胃肠炎、风湿痹痛、跌打损伤、骨折、痛经、产后瘀血腹痛、疝气痛等症; 千斤拔,性味:甘、涩、平,具有祛风利湿、强筋壮骨、活血解毒之功效,用于治疗风湿痹痛、腰肌劳损、四肢痿软、跌打损伤、咽喉肿痛等症;茜草,性味:苦、寒,具有凉血止血、活血化瘀之功效,用于治疗血热咯血、吐血、衄血、尿血、便血、崩漏、经闭、产后瘀阻腹痛、跌打损伤、风湿痹痛、黄疸、疮痈、痔肿;飞来参,性味:甘、平,具有健脾润肺、止咳、调经之功效,用于治疗脾虚劳倦、泄泻、肺劳咳痰带血、眩晕潮热、盗汗自汗、月经不调、带下;甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒等症。
[0013] 本发明药物是基于中医治疗血瘀型癥瘕的辨病与辨证相结合的原则,从药理作用及作用机制认为:就血瘀型癥瘕,本发明所提供的药物中的各原料中药药效共奏,对上述血瘀型癥瘕有很好的治疗效果。具体实施方式
[0014] 本发明就是针对上述血瘀型癥瘕的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述。实施例1:一种治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:三七8g、凌霄花5g、醋穿山甲8g、鹿角8g、赤芍10g、苏木8g、瓦楞子12g、刘寄奴10g、牡丹皮8g、郁金12g、素馨花10g、山楂10g、木香10g、鸡内金10g、五爪龙42g、黑老虎12g、千斤拔23g、茜草12g、飞来参70g、甘草8g。
[0015] 实施例2:一种治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:三七9g、凌霄花5.5g、醋穿山甲9g、鹿角9g、赤芍llg、苏木9g、瓦楞子14g、刘寄奴llg、牡丹皮9g、郁金14g、素馨花llg、山楂llg、木香llg、鸡内金llg、五爪龙50g、黑老虎14g、千斤拔 26g、茜草14g、飞来参80g、甘草9g。
[0016] 实施例3:一种治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:三七l〇g、凌霄花6g、醋穿山甲10g、鹿角10g、赤芍12g、苏木10g、瓦楞子16g、刘寄奴12g、 牡丹皮l〇g、郁金16g、素馨花12g、山楂12g、木香12g、鸡内金12g、五爪龙60g、黑老虎16g、千斤拔30g、茜草16g、飞来参90g、甘草10g。[0〇17] 典型病例经临床诊断治疗血瘀型癥瘕患者共815例,年龄为37岁以上的415例,只有400例为37岁以下。815例患者中痊愈的795例,显效的20例,总有效率达100%。

Claims (3)

1.一种治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组合物的各个组分及其 质量份比如下所示:三七3〜10g、凌霄花3〜6g、醋穿山甲5〜10g、鹿角5〜10g、赤苟6〜12g、苏木3〜10g、瓦 愣子3〜16g、刘寄奴5〜12g、牡丹皮6〜10g、郁金8〜16g、素馨花5〜12g、山楂3〜12g、木香3 〜12g、鸡内金3〜12g、五爪龙30〜60g、黑老虎9〜16g、千斤拔15〜30g、茜草10〜16g、飞来 参50〜90g、甘草2〜10g。
2.根据权利要求1所述的治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组合物 的各个组分及其质量份比如下所示:三七4〜9g、凌霄花4〜5.5g、醋穿山甲6〜9g、鹿角6〜9g、赤苟7〜llg、苏木4〜9g、瓦愣 子4〜14g、刘寄奴6〜llg、牡丹皮7〜9g、郁金10〜14g、素馨花6〜llg、山楂4〜llg、木香4〜 llg、鸡内金4〜llg、五爪龙35〜50g、黑老虎10〜14g、千斤拔18〜26g、茜草11〜14g、飞来参 60〜80g、甘草3〜9g。
3.根据权利要求1至2所述的治疗血瘀型癥瘕的中药组合物,其特征在于,所述中药组 合物的各个组分及其质量份比如下所示:三七8g、凌霄花5g、醋穿山甲8g、鹿角8g、赤芍10g、苏木8g、瓦楞子12g、刘寄奴10g、牡丹 皮8g、郁金12g、素馨花10g、山楂10g、木香10g、鸡内金10g、五爪龙42g、黑老虎12g、千斤拔 23g、茜草12g、飞来参70g、甘草8g。
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