CN106237090A - A kind of coloclysis Chinese medicine composition treating ulcerative colitis - Google Patents
A kind of coloclysis Chinese medicine composition treating ulcerative colitis Download PDFInfo
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Abstract
The invention discloses a kind of coloclysis Chinese medicine composition treating ulcerative colitis, it is made up of the raw material of following parts by weight: Herba Agrimoniae 20 30 parts, Herba Euphorbiae Humifusae 20 30 parts, Radix Sophorae Flavescentis 20 30 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 30 parts, burnt Radix Sanguisorbae 20 30 parts, Galla Chinensis 20 30 parts, the Radix Paeoniae Alba 30 50 parts.The present invention, with dispeling disease and evil, repairs the impaired mucosa of intestinal, and repairing intestinal normal physiological function is starting point, monarch drug, ministerial drug, adjuvant drug, making medicine complement each other, cooperate generation synergism, and compatibility is not only the most thoughtful, and make a distinction between the important and the lesser one, raise the profit of all medicines, make the fraud of all medicines, not only heat clearing and damp drying, eliminating fire and detoxication, eliminate the poison that intestinal is damp and hot, also removing dampness sore is had both, hemostasis antidiarrheal, putrefaction-removing granulation-promoting, the effect of relieving spasm to stop pain.The reaction it is thus possible to effectively reduce inflammation, promotes ulcer healing, adjusts body's immunity, obvious for damp-heat type Mild and moderate ulcerative colitis patient's effect, and the few power of medicine is special, takes stopgap measures and effects a permanent cure, without obvious toxic-side effects, has the effect got twice the result with half the effort.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of coloclysis Chinese medicine composition treating ulcerative colitis
Thing.
Background technology
Ulcerative colitis is the inflammatory bowel that a kind of pathogenic factor so far is the clearest and the most definite, and clinical manifestation is predominantly
Stomachache, diarrhoea, mucopurulent bloody stool and tenesmus etc., state of an illness weight differs.Its Pathologic changes is mainly limited to the viscous of colon
Film and tela submucosa, severe patient can invade muscle layer and placenta percreta, mainly involve rectum, sigmoid colon, and minority can involve total colectomy.
" diarrhoea ", " dysentery ", " spouting bleeding from anus ", " hemorrhoidal hamorrhage " category can be belonged in the traditional Chinese medical science.
Chinese medicine think primary disease it is crucial that spleen-stomach dysfunction, insufficiency of the spleen leading to overabundance of dampness is the key factor of primary disease.Main with following
Factor, about 1. eating and drinking without temperance hyperalimentations, is stagnated and is not changed；Or throw off restraint food greasy and surfeit flavour, and pungent rich, damp and hot interior life, pent up intestinal
Stomach；Or eat the unclean thing of raw food by mistake, and causing spleen injury, transformation failure of spleen, essence of water and grain can not transfer absorption, stops as humidity hysteresis, and
Cause and have loose bowels.2. the uncomfortable the liver failing to maintain the normal flow of QI of feelings will, deficiency-weakness of spleen-QI, or originally have dyspepsia, or dampness, and smooth because of feelings will again, it is worried angry
Anger, then stagnated QI transforming into fire, cause liver mistake bar and reach, lose in catharsis, and perverse and unreasonable manner takes advantage of spleen to violate stomach, incoordination between the spleen and stomach, dysfunction of the spleen in transportation and transformation, forms and has loose bowels.3.
With the passing of time weakness of the spleen and stomach eating and drinking without temperance, may result in weakness of the spleen and stomach.Deficiency of spleen-QI, transporting is not good for, be cause water counter become wet, paddy counter become stagnant,
Humidity hysteresis does not goes, clear QI being mixed up with turbid QI, mix and under, then become have loose bowels.4. kidney yang deficiency is got old and weak or after prolonged illness, damages kidney yang, life
The fire of door is not enough, then can not warm spleen soil, transporting mistake department, cause and have loose bowels.
Primary disease occurs many because of natural endowment deficiency, or ferritic weakness of the spleen and stomach, or eating and drinking without temperance, disorder of emotion, being invaded by exogenous pathogen
Etc. causing, taste, visceral dysfunction, qi activity disturbance, qi depression to blood stasis, goldbeater's skin and venation are impaired.Therefore primary disease with weakness of the spleen and stomach is
Deficiency in origin, sick with damp-heat accumulation, stagnation of blood stasis for the deficiency in origin and excess in superficiality that mark is real.
Modern medicine thinks that the ulcerative colitis cause of disease has: (1), courses of infection: due to this disease and bacillary dysentery
The most similar, and pathogenic bacteria can be turned out from the feces of patient, and apply antibiotic to have certain curative effect, so very
Many people think that this disease causes owing to antibacterial infects.And a lot of people are transformed into for exedens knot from bacillary dysentery
Enteritis, has close relationship it is believed that may infect with antibacterial.(2), Nervous and Mental Factors: mental disorder can result in plant god
Through function occur imbalance, such that it is able to cause intestinal movement hyperfunction, followed by muscle occur spasm, blood vessel occur shrink, organize out
Existing ischemia, capillary permeability increase, and have ultimately formed intestinal wall inflammation and ulcer.(3), inherited genetic factors: burst in American-European countries
The Probability of ulcer colitis is significantly larger than China, and there is familial, and racial sickness rate there is also
Significantly difference, so it is believed that ulcerative colitis has the biggest relation with heredity.(4), the local of large intestine endoenzyme because of
Element: if intestinal wall secrets out of too much lysozyme, proteolytic enzyme etc., the protective effect of intestinal mucus will be destroyed, it is possible to
Antibacterial is invaded, thus intestinal mucosa can be occurred downright bad, then resulted in the generation of ulcerative colitis.(5), anaphylaxis is anti-
Should be with defensive enginery obstacle: Cucumber may result in intestinal anaphylactic reaction occurs thus cause ulcerative colitis send out
Make.(6), role of autoimmune factors: owing to ulcerative colitis usually can concurrently rheumatoid arthritis, Hashimoto's disease, erythema wolf
The autoimmune diseasees such as skin ulcer, and good curative effect can be obtained if treating with the medicine for the treatment of immune disease,
It is believed that ulcerative colitis causes due to role of autoimmune factors.
Generally ulcerative colitis can be divided into surgical intervention and medical treatment, substantially based on medical treatment, clinical treatment
Conventional Western medicine is salicylic acid, steroid and immune formulation three class medicine, total effective rate 70%-80%, but has hepatorenal damage and treatment more
The deficiency of journey length, and somewhat expensive.Treatment by Chinese herbs has good therapeutic effect, but uses conventional Chinese medicine decoction to decoct pretty troublesome, clothes
With more pained, bring a lot of inconvenience to patient.
Summary of the invention
The invention aims to solve technical problem present in prior art, it is provided that a kind of evident in efficacy, operation
Easy, with low cost, have no side effect, the coloclysis Chinese medicine composition for the treatment of ulcerative colitis that cure rate is high.
In order to achieve the above object, the present invention is by the following technical solutions: in a kind of coloclysis treating ulcerative colitis
Drug composition, it is made up of the raw material of following parts by weight: Herba Agrimoniae 20-30 parts, Herba Euphorbiae Humifusae 20-30 part, Radix Sophorae Flavescentis 20-30
Part, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30 parts, burnt Radix Sanguisorbae 20-30 part, Galla Chinensis 20-30 part, Radix Paeoniae Alba 30-50 part.
Preferably, the coloclysis Chinese medicine composition of this treatment ulcerative colitis is made up of the raw material of following parts by weight: celestial
Crane grass 30 parts, Herba Euphorbiae Humifusae 20 parts, Radix Sophorae Flavescentis 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, burnt Radix Sanguisorbae 20 parts, Galla Chinensis 20 parts, the Radix Paeoniae Alba 30 parts.
Hinge structure of the present invention has the advantages that the coloclysis Chinese medicine of the treatment ulcerative colitis of the present invention
Compositions is made up of Herba Agrimoniae, Herba Euphorbiae Humifusae, Radix Sophorae Flavescentis, Pseudobulbus Bletillae (Rhizoma Bletillae), burnt Radix Sanguisorbae, Galla Chinensis, the Radix Paeoniae Alba, wherein Herba Agrimoniae: puckery is restrained, merit
Energy astringing to arrest bleeding, relieving diarrhea with astringents dysentery, particularly suitable for chronic dysentery and prolonged illness dysentery, there are astringing to arrest bleeding, qi-restoratives, dysentery relieving, removing toxic substances disappears
The effect such as swollen.Burnt Radix Sanguisorbae: return large intestine channel, property picric acid, effect cooling blood for hemostasis, heat-clearing and toxic substances removing, sore of subsiding a swelling, cure mainly haematemesis, spitting of blood,
Hematuria, have blood in stool, hemorrhoidal bleeding, burn due to hot liquid or fire, snake bite and insect sting, there is antibacterial action, shorten the bleeding time, have hemostasis to thin vessels is hemorrhage
Effect, moreover it is possible to controlling to infect, minimizing is oozed out, and promotes new epithelial growth.Herba Euphorbiae Humifusae: nature and flavor are pungent flat, heat-clearing and toxic substances removing dysentery relieving, removing heat from blood
Hemostasis, having hemostasis and not staying the feature of the stasis of blood, for dysentery, having loose bowels, and hemoptysis, hematuria, has blood in stool.Radix Sophorae Flavescentis: the property of bitter cold is relatively strong, the most clearly
Hot dampness, diuresis of holding concurrently again, wind dispelling insecticide, main damp-heat dysentery, discharging fresh blood stool, skin pruritus, noxious dampness skin infection, owing to Radix Sophorae Flavescentis is pure the moon
Product, settle descending, be usually used in treat the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels (referring to lower body part) the damp and hot disease relatively contained, such as damp-heat dysentery, pyretic stranguria, red and white leukorrhea
Inferior disease.Galla Chinensis: sour-puckery flavor is cold in nature, enters stomach, large intestine channel, has hemostasis removing toxic substances, effect of relieving diarrhea with astringents, and Galla Chinensis contains tan
Acid, plays astriction: tannic acid has precipitation to protein, and after skin, mucosal contact tannic acid, its tissue protein is i.e. coagulated
Gu, and formed one layer of tunicle in astriction, the most oppressed contraction of thin vessels simultaneously, blood clotting and have anastalsis, additionally
Staphylococcus aureus streptococcus, bacillus pyocyaneus, dysentery bacterium, escherichia coli etc. all there is the most antibacterial and bactericidal action.
The Pseudobulbus Bletillae (Rhizoma Bletillae): cold in nature, function astringing to arrest bleeding, detumescence and promoting granulation；There are hemostasis, pain relieving, effect of promotion ulcer healing, platelet can be strengthened
Three factor actives, notable shortening clotting time and thrombinogen form the time, suppress plasmin enzymatic activity, to local hemorrhage
There is anastalsis；Simultaneously to staphylococcus aureus, bacillus subtilis, tubercule bacillus has inhibitory action.The Radix Paeoniae Alba: bitter, acid is slightly cold, merit
Can be nourished blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG, can treat dysentery stomachache, and paeoniflorin contained by it has preferable analgesic effect.With
In upper each Chinese medicinal components, Herba Euphorbiae Humifusae, Radix Sophorae Flavescentis nature and flavor bitter cold, there is heat clearing and damp drying, the effect of eliminating fire and detoxication is monarch drug.Burnt Radix Sanguisorbae, celestial being
Crane grass, Pseudobulbus Bletillae (Rhizoma Bletillae) cooling blood for hemostasis, astringing intestine to stop diarrhea hemostasis, removing dampness sore, putrefaction-removing granulation-promoting, play important during treatment ulcerative colitis
Effect, for ministerial drug；Galla Chinensis removing dampness sore, promotes ulcer healing, for adjuvant drug；The Radix Paeoniae Alba is invigorated blood circulation, relieving spasm to stop pain, can be by changing blood
Liquid stream degeneration and improve microcirculation to eliminate the cause of disease, to promote the reparation of colon, " regulating QI is the heaviest from removing, promoting the circulation of blood the most just pus from
More ", for making medicine.The present invention, with dispeling disease and evil, repairs the impaired mucosa of intestinal, and repairing intestinal normal physiological function is starting point, monarch
Medicine, ministerial drug, adjuvant drug, making medicine complement each other, cooperate generation synergism, and compatibility is not only the most thoughtful, and makes a distinction between the important and the lesser one, and raises
The profit of all medicines, makes the fraud of all medicines, not only heat clearing and damp drying, eliminating fire and detoxication, eliminates the poison that intestinal is damp and hot, also have both removing dampness sore, only
Blood antidiarrheal, putrefaction-removing granulation-promoting, the effect of relieving spasm to stop pain.The reaction it is thus possible to effectively reduce inflammation, promotes ulcer healing, adjusts body
Immunologic function, obvious for damp-heat type Mild and moderate ulcerative colitis patient's effect, the few power of medicine is special, takes stopgap measures and effects a permanent cure, without substantially poison
Side effect, has the effect got twice the result with half the effort.It addition, the present invention is specific to the coloclysis Chinese medicine composition of ulcerative colitis,
Herbal enema Chinese medicine composition has its advantage than oral drugs, and enema therapy can make the through sick institute of medicine, allows high drug concentration
Act on focus, more direct to pathological changes effect, accelerate the rehabilitation of patient, and avoid and oral gastrointestinal is stimulated,
Be conducive to playing the effect of medicine and reaching dispeling disease and evil, the effect of damaged tissue repair, and without liver first-pass effect, and gastrointestinal
Road reacts, and effect is better than simple Western medicine.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of coloclysis Chinese medicine composition treating ulcerative colitis, it is made up of the raw material of following content: Herba Agrimoniae 30g,
Careless 20 g of brocade, Radix Sophorae Flavescentis 20 g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 g, burnt Radix Sanguisorbae 20 g, Galla Chinensis 20 g, the Radix Paeoniae Alba 30 g.
Add water during use in above-mentioned Chinese medicine composition 500ml, decocts to 200ml, and filtered through gauze removes slag, and places medicinal liquid Wen Liang
To 35-45 DEG C.Every day twice, each 100ml, sleeps coloclysis in front and secondary morning.
Administration time and method:
Treatment time, for sleep front half an hour and secondary morning every night, drains defecation, and patient takes left lateral position, and padded buttocks will once
Property sputum aspirator tube one end paraffine oil, insert anus about 15cm, extract above-mentioned medicinal liquid 100ml altogether with 50ml syringe by several times, slowly
Injecting perfusion, rate of administration should not be too fast, feels that hypogastric region is warm with patient, does not produce awareness of defecation and be advisable, after pushing away medicine, advises trouble
Person continues to keep left lateral position about 30 minutes, then keeps dorsal position, makes medicinal liquid be maintained at the position of sigmoid colon and rectum as far as possible
Putting, make medicinal liquid be fully contacted with pathological changes mucosa, extend the retention time of medicinal liquid, twice on the one, surrounding is a course for the treatment of.
Embodiment 2
A kind of coloclysis Chinese medicine composition treating ulcerative colitis, it is made up of the raw material of following content: Herba Agrimoniae 20 g,
Careless 20 g of brocade, Radix Sophorae Flavescentis 30 g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 g, burnt Radix Sanguisorbae 30 g, Galla Chinensis 30g, the Radix Paeoniae Alba 30 g.
Add water during use in above-mentioned Chinese medicine composition 500ml, decocts to 200ml, and filtered through gauze removes slag, and places medicinal liquid Wen Liang
To 35-45 DEG C.Every day twice, each 100ml, sleeps coloclysis in front and secondary morning.
Administration time and method are with embodiment 1.
Embodiment 3
A kind of coloclysis Chinese medicine composition treating ulcerative colitis, it is made up of the raw material of following content: Herba Agrimoniae 20 g,
Careless 30 g of brocade, Radix Sophorae Flavescentis 20 g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, burnt Radix Sanguisorbae 20g, Galla Chinensis 20g, the Radix Paeoniae Alba 50 g.
Add water during use in above-mentioned Chinese medicine composition 500ml, decocts to 200ml, and filtered through gauze removes slag, and places medicinal liquid Wen Liang
To 35-45 DEG C.Every day twice, each 100ml, sleeps coloclysis in front and secondary morning.
Administration time and method are with embodiment 1.
Clinical trial:
One, physical data
In 68 example patients, male 36 examples, female 32 example, minimum 18 years old of age, maximum 65 years old, the course of disease 5 months to 6 years.Patient is equal
There are stomachache in various degree, diarrhoea, tenesmus, mucopurulent bloody stool, are the exedens knot of UC(through electronic colonoscope or definitive pathological diagnosis
Enteritis) patient.
Two, diagnostic criteria:
Close with reference to finalizing a text after reporting in the 7th the national disease for digest academic conference of Chinese Medical Association that Jinan is held in May, 2007
In the diagnostic criteria that UC is formulated:
1, clinical manifestation: be presented with continuing or the stomachache of Recurrent seizures, diarrhoea, mucopurulent bloody stool, tenesmus and have different journey
The General Symptoms of degree, can have the parenteral performances such as joint, skin, eye, mouth and liver and gall.
2, colonoscopy: (1), mucosa vascular lake are fuzzy, disorder, hyperemia, edema, matter is crisp, hemorrhage and purulent secretion
Thing adheres to, and common mucosa is that fine particulate is coarse.(2), mucosa have multiple, diffusivity is rotten to the corn or ulcer.(3), chronic disease
Seen from person, haustra of colon shoals, rust or disappearance, false polyp and bridge shape mucosa formation etc..
3, barium enema inspection: the slightly unrest of (1), mucosa or granular change.(2), intestinal tube edge be sawtooth sample or burr sample,
Multiple little filling defect is seen on intestinal wall.(3), the obvious cripetura of intestinal tube, pouch disappear present lead pipe shape.
4, mucosa Pathologic changes:
(1), active stage:Diffusivity, chronic inflammatory cells and neutrophilic granulocyte is had, the leaching of eosinophilic granulocyte in lamina propria
Profit.Crypts has infiltration and the cryptitis having neutrophilic granulocyte between the infiltration of acute inflammation cell, especially epithelial cell, even may be used
Form crypt abscess, abscess can be had to burst into lamina propria.Crypts epithelial proliferation, goblet cell reduces.Visible mucosal surface is rotten
Rotten, ulcer also accompanies granulation tissue hyperplasia.
(2) catabasis:, without neutrophilic granulocyte, chronic inflammatory cell reduces；Crypts is not of uniform size, and form is irregular,
Arrange irregular；Gap between glandular epithelium and muscular layer of mucosa is broadening；Paneth's cell metaplasia.
Three, Therapeutic Method
Giving the liquid medicine enema treatment that the embodiment of the present invention 1 Chinese medicine composition prepares, surrounding is a course for the treatment of, and treatment time is every night
Sleeping front half an hour, and morning is the most once, drains defecation, patient takes left lateral position, and padded buttocks, by disposal sputum collecting cannula one end
Paraffine oil, inserts anus about 15cm, extracts above-mentioned medicinal liquid 100ml by several times with 50ml syringe, slowly injects perfusion, injection speed
Degree should not be too fast, feels that hypogastric region is warm with patient, does not produce awareness of defecation and be advisable, and after pushing away medicine, advises patient to continue on the left of holding
Clinostatism about 30 minutes, then keeps dorsal position, makes medicinal liquid be maintained at the position of sigmoid colon and rectum as far as possible, makes medicinal liquid and pathological changes
Mucosa is fully contacted, and extends the retention time of medicinal liquid.
Four, therapeutic effect:
With reference in ulcerative colitis in " new drug (Chinese medicine) guideline of clinical investigations " that Ministry of Public Health bureau of drug administration develops and publishes
Doctor's CM syndrome differentiation criterion judges curative effect.
(1), comprehensive therapeutic effect evaluation criteria is (with reference to the whole nation, Taiyuan in 1993 chronic non infectious intestinal tract disease scientific seminar
Formulation standard)
(1), effective (or complete incidence graph) clinical symptom disappearance, colonoscope check mucosa is normal, drug withdrawal or only use maintenance dose medicine,
Observe 6 months without recurrence.
(2), clinical symptoms disappears substantially, colonoscope check mucosa mild inflammation reacts and part pseudopolyp is formed.
(3), clinical symptoms, scope and pathologic finding are without improving.
(2), mucosa infection efficacy assessment standard
(1), effectiveIntestinal mirror check mucosa infection recovers normal, or ulcer focus has formed cicatrix,Intestinal mirror check mucosal disease
Become recovery extent and reach more than two grades.
(2), effective intestinal mirror check mucosa infection recovery extent reaches more than one-level.
(3), invalid intestinal mirror check mucosa infection be not up to above standard, even add severe one.
(3), observation index and method
(1) safety indexes
1, general health check-up project (breathing, pulse, body temperature, blood pressures etc.), before and after treatment, each row is once.
2, before and after blood, urine, stool routine examination (chemically examining containing occult blood) are treated, each row is once.
3, darling renal function, before and after treatment, each row is once.
(2) curative effect observation index
1, the stomachache of comparison therapy Patients Before And After, diarrhoea.Tenesmus, mucopurulent bloody stool, the clinical manifestation such as fever of the body, oliguria with reddish urine
And mark respectively, 2, the change of diseased region mucosa under colonoscope before and after comparison therapy.
(5), therapeutic outcome is shown in Table one
Table one: clinical trial therapeutic outcome
(6), untoward reaction: obvious untoward reaction all do not occur in all patients.
Contrast test
1,1 physical data
Patients of ulcerative colitis 66 example selecting the court to accept for medical treatment 10 months Mays in 2014, all meets in sixth version " internal medicine "
The diagnostic criteria of this disease.Wherein, male 38 examples, female 28 example, age 20-68 year, average 35 years old, the course of disease 2 months to 12 years, averagely
12 months, pathological changes involved rectum 29 example, sigmoid colon 32 example, left hemicolon 5 example.After all patients are all with stomachache, diarrhoea, pain in the abdomen
Weight, mucopurulent bloody stool are main clinic symptoms.The age of two groups of patients, sex, the course of disease, clinical symptoms etc. compare, and difference is without system
Meaning (p > 0.05) learned by meter, has comparability.
1,2 method
In this test, matched group uses Xianglian Wan treatment, oral, a ball, and three times on the one, the course for the treatment of is surrounding, and observation group uses
The Chinese medicine composition enema treatment of the embodiment of the present invention 1, Herba Agrimoniae 30g, Herba Euphorbiae Humifusae 20 g, Radix Sophorae Flavescentis 20 g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 g, Jiao Di
Elm 20 g, Galla Chinensis 20 g, the Radix Paeoniae Alba 30 g.Add water 500ml, decocts to 200ml, treatment time for sleep front half an hour every night, and
Each 100ml retention enema in two day morning, twice of an auxiliary medicine coloclysis, it is used in conjunction surrounding.
1,3 curative effect determinate standard:
The clinical symptom disappearance of patient, every inspection intestinal mucosa such as colonoscope is normal, and stool routine examination inspection is considered as without red, leukocyte
Cure.Patient clinical symptom disappears substantially, colonoscopy intestinal mucosa mild inflammation, and stool routine examination inspection has the reddest, the thinnest
Born of the same parents are considered as taking a turn for the better.It is invalid that patient clinical symptom and colonoscope etc. check that nothing improvement is considered as.Cure+take a turn for the better=the most effective.
1,4 statistical procedures
Use SPSS11.0 software kit analytical data, enumeration data X2Inspection, p < 0.05 is that difference is statistically significant.
1,5 result
(1) curative effect
The total effective rate of observation group be 90.1% matched group be that 81.8% liang of group compares, difference is statistically significant, (p < 0.05) have
Volume data is shown in Table two.
Table two: observation group and matched group Comparison of therapeutic
(2) there is inappetence one example in untoward reaction matched group, and adverse reaction rate is 3%, and observation group has no adverse reaction, no
Good reaction incidence rate is 0.
1,6 discuss
Ulcerative colitis major lesions, at rectum, sigmoid colon, creeps up and can involve descending colon, even total colectomy.It is to invade
And colonic mucosa and SM chronic nonspecific inflammatory diseases, its Pathologic changes is mainly limited to the mucosa of colon and viscous
Film lower floor, severe patient can invade muscle layer and placenta percreta.Clinical manifestation predominantly stomachache, diarrhoea, mucopurulent bloody stool and tenesmus
Deng, state of an illness weight differs.The coloclysis Chinese medicine composition effect of the present invention is direct, and local drug concentration is high, and therapeutic effect is preferable, and
And avoid gastrointestinal irritation, and untoward reaction is few, is worthy of popularization.
Model case
Case one, patient Zhang, man, 46 years old, discontinuity was suffered from diarrhoea 4 years, shows effect 1 month, examines times of defecation and increase, day 5-7
Secondary, shapeless, it is sometimes accompanied by mucus, has pus and blood, oral " cisapride " cures.Hereafter, it is interrupted outbreak, 1 month cause drink
Eating improper and show effect, without Nausea and vomiting, left lower quadrant dull pain is uncomfortable, and after defecation, stomachache can be alleviated, loose stool, has pus pus and blood, accompanies pain in the abdomen
Rear heavy.Weak, xerostomia, to sleep poor, urine is normal.Have a medical check-up: abdomen is flat, soft, without tenderness.Liver spleen does not touches.Borborygmus is normal.Physiology
Reflection exists, and pathologic reflex is not drawn.Patient looks into electronic colonoscope and shows: rectum, sigmoid mucosa are congested, are dispersed in rotten to the corn and shallow
Ulcer.Take medicine of the present invention, treat three courses for the treatment of, recovery from illness, follow up a case by regular visits to after half a year without recurrence.
Case two, patient Xu certain, female, 35 years old, patient suffered from diarrhoea 3～4 every day, left lower abdominal pain, mucosanguineous feces, pain in the abdomen
Rear heavy 1 year, x-ray is reported as: ulcerative colitis.Electronics checks: the obvious congestion and edema of mucosa, it is seen that ulcer many places, surface is attached
White pus tongue, mucosa matter is crisp, and that touches is the most hemorrhage, is diagnosed as ulcerative colitis.Once in local multiple hospitals treatment, effect is owed
Good, to take medicine of the present invention, treat 2 courses for the treatment of, suffer from diarrhoea 1～2 time, left lower abdominal pain alleviates, and stool shapes, depletion of blood.Continue to consolidate
Admittedly fully recover after treating a course for the treatment of.
Case three, patient Zhao, female, 39 years old.Recurrent diarrhea, more than ten years of passing stool with blood and pus, time when rushing down only, just in time have pus and blood,
Have not well during stool, indigestion and loss of appetite, weak, lusterless complexion, become thin.Catch a cold whenever or improper diet then induces.Again because of drink before 2 months
Eating improper and show effect, left lower quadrant dull pain is uncomfortable, and after defecation, stomachache can be alleviated, and loose stool, in yellow, without pus and blood.Take with prodrug,
Without being clearly better.Abdomen is flat, soft, without tenderness.Liver spleen does not touches.Borborygmus is normal.Physiological reflex exists, and pathologic reflex is not drawn.
Patient looks into electronic colonoscope and shows: rectum, sigmoid mucosa are congested, are dispersed in erosion and fester.Western medicine diagnose is exedens knot
Enteritis.Apply medicine of the present invention, treat two months each symptoms and know more, follow up a case by regular visits to after half a year without recurrence.
Claims (2)
1. the coloclysis Chinese medicine composition treating ulcerative colitis, it is characterised in that: it is by the raw material of following parts by weight
Composition: Herba Agrimoniae 20-30 parts, Herba Euphorbiae Humifusae 20-30 part, Radix Sophorae Flavescentis 20-30 part, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20-30 parts, burnt Radix Sanguisorbae 20-30
Part, Galla Chinensis 20-30 part, Radix Paeoniae Alba 30-50 part.
A kind of coloclysis Chinese medicine composition treating ulcerative colitis the most according to claim 1, it is characterised in that: it by
The raw material composition of following parts by weight: Herba Agrimoniae 30 parts, Herba Euphorbiae Humifusae 20 parts, Radix Sophorae Flavescentis 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, burnt Radix Sanguisorbae 20 parts, five
Gall nut 20 parts, the Radix Paeoniae Alba 30 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320659A (en) * | 2017-06-16 | 2017-11-07 | 杭州医学院 | It is a kind of to be used to treat Chinese medicine composition of ulcerative colitis and preparation method thereof |
| CN108992521A (en) * | 2017-06-07 | 2018-12-14 | 徐定清 | A kind of medicine pill of colonic ulcer bolt |
| CN113648375A (en) * | 2021-09-17 | 2021-11-16 | 贵州斛妍堂生物科技有限公司 | A Chinese medicinal composition for treating hemorrhoid, and its preparation method |
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| CN102293842A (en) * | 2011-08-25 | 2011-12-28 | 广州固志医药科技有限公司 | Preparation for treating ulcerative colitis and preparation method thereof |
| CN102670987A (en) * | 2012-06-28 | 2012-09-19 | 高娟 | Traditional Chinese medicine combination for treating ulcerative colitis and preparation method thereof |
| CN104606622A (en) * | 2015-02-03 | 2015-05-13 | 林亚梅 | Traditional Chinese medicine for treating ulcerative colitis |
| CN105395975A (en) * | 2015-12-23 | 2016-03-16 | 方晓华 | Enema traditional Chinese medicine composition treating ulcerative colitis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101912531A (en) * | 2010-08-13 | 2010-12-15 | 万秀玲 | Chinese medicinal enema decoction for treating colonitis |
| CN102293842A (en) * | 2011-08-25 | 2011-12-28 | 广州固志医药科技有限公司 | Preparation for treating ulcerative colitis and preparation method thereof |
| CN102670987A (en) * | 2012-06-28 | 2012-09-19 | 高娟 | Traditional Chinese medicine combination for treating ulcerative colitis and preparation method thereof |
| CN104606622A (en) * | 2015-02-03 | 2015-05-13 | 林亚梅 | Traditional Chinese medicine for treating ulcerative colitis |
| CN105395975A (en) * | 2015-12-23 | 2016-03-16 | 方晓华 | Enema traditional Chinese medicine composition treating ulcerative colitis and preparation method thereof |
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| CN108992521A (en) * | 2017-06-07 | 2018-12-14 | 徐定清 | A kind of medicine pill of colonic ulcer bolt |
| CN107320659A (en) * | 2017-06-16 | 2017-11-07 | 杭州医学院 | It is a kind of to be used to treat Chinese medicine composition of ulcerative colitis and preparation method thereof |
| CN107320659B (en) * | 2017-06-16 | 2020-09-22 | 杭州医学院 | A Chinese medicinal composition for treating ulcerative colitis and preparation method thereof |
| CN113648375A (en) * | 2021-09-17 | 2021-11-16 | 贵州斛妍堂生物科技有限公司 | A Chinese medicinal composition for treating hemorrhoid, and its preparation method |
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Application publication date: 20161221 |