CN108992521A - A kind of medicine pill of colonic ulcer bolt - Google Patents

A kind of medicine pill of colonic ulcer bolt Download PDF

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Publication number
CN108992521A
CN108992521A CN201710425364.8A CN201710425364A CN108992521A CN 108992521 A CN108992521 A CN 108992521A CN 201710425364 A CN201710425364 A CN 201710425364A CN 108992521 A CN108992521 A CN 108992521A
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bolt
ulcer
medicine pill
radix
colonic ulcer
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CN201710425364.8A
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徐定清
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The present invention discloses a kind of medicine pill of colonic ulcer bolt, by: the coptis, Radix Paeoniae Alba, radix saposhnikoviae, Chinese gall, Rhizoma Atractylodis Macrocephalae, hairyvein agrimony, alum, dried orange peel, Radix Salviae Miltiorrhizae, etc. 9 Chinese prescription compatibilities, cooling blood and hemostasis of the present invention, coordination of cold and heat, it is clearing heat and detoxicating, receive and be intended to stop dysentery, relieving pain by regulating middle-JIAO, purging the liver of pathogenic fire tonifying spleen, activating microcirculation and removing stasis medicinal, astringing to arrest bleeding, life go corruption, restore intestinal mucosa, repairing ulcer face inhibits microvascular corrosion cast, reduces blood viscosity, improve microcirculation and intestinal mucosa blood supply, promotes ulcer surface healing.1, Normal Physiological Function is small without influence, or very, has no toxic side effect.2, effect is non-specific and wide spectrum.3, there is adjusting physiological action, cooling blood and hemostasis, coordination of cold and heat is clearing heat and detoxicating, convergence and dysentery, relieving pain by regulating middle-JIAO, purging the liver of pathogenic fire tonifying spleen, activating microcirculation and removing stasis medicinal, and astringing to arrest bleeding life goes corruption, improves microcirculation and intestinal mucosa blood supply, promotes ulcer surface healing.4, rehabilitation can be mitigated to patient clinical sign, and to ulcerative colitis reparation.

Description

A kind of medicine pill of colonic ulcer bolt
Technical field:
The present invention relates to Chinese medicine nostrum, especially a kind of medicine pill of colonic ulcer bolt.
Background technique:
It is interior through saying: " large intestine person, the internal organs preached." " turbid QI stagnating in middle-JIAO person, speech trough all enter stomach, and vital essence is only infused in lung, turbid It stays in stomach, says that cold-dampness is uncomfortable, diet is without cease, and diease occurrence is in stomach ".For the physiology of the lung and the large intestine being interior-exteriorly related, large intestine is The organ for the object that conveying small intestine has digested, " turbid QI stagnating in middle-JIAO " is to say that the foods such as trough are all to be digested and assimilated by stomach, and generate Precise and tiny gas then it is upper it is defeated arrive lung, foul smell is trapped among stomach, if stomach cold heat is improper, if diet is not controlled, just Disease can be generated in stomach.In addition the modern life rhythm and pace of moving things is speeded, and mental element merging fever and chills are uncomfortable, and irregular eating promotees Digestive system pathology is set to grow thickly, large intestine is preached imbalance, and turbid pathogenic factor corruption, which is looked into, to be excreted on time, there is constipation diarrhea and hematochezia, Colorectal mucosa is injured, exacerbation injures intestinal wall, rotten to the corn and ulcer.And the colonic ulcer embolism of Chinese medicine enters anus, cooling blood and hemostasis, fever and chills Heibei provincial opera, clearing heat and detoxicating, convergence and dysentery relieving pain by regulating middle-JIAO, purging the liver of pathogenic fire benefit spleen activating microcirculation and removing stasis medicinal, astringing to arrest bleeding, myogenic go corruption, restore intestinal mucosa, Repairing ulcer face inhibits microvascular corrosion cast, reduces blood viscosity, improves circulation and intestinal mucosa blood supply promotes ulcer surface healing, It is curative for effect.
Summary of the invention:
Take: the coptis, Radix Paeoniae Alba, radix saposhnikoviae, Chinese gall, Rhizoma Atractylodis Macrocephalae, hairyvein agrimony, alum, dried orange peel, Radix Salviae Miltiorrhizae, etc. 9 taste Chinese medicines through processing Afterwards, selected dry attritioning crosses 120 meshes, and water is mixed as suppository (6g), and once in the morning and once at night, each 6g, anus sterilization is put into rectum, Surrounding is as a treatment course.
Cooling blood and hemostasis of the present invention, coordination of cold and heat, it is clearing heat and detoxicating, receive and be intended to stop dysentery, relieving pain by regulating middle-JIAO, purging the liver of pathogenic fire tonifying spleen, activating microcirculation and removing stasis medicinal, Astringing to arrest bleeding, life go corruption, restore intestinal mucosa, and repairing ulcer face inhibits microvascular corrosion cast, reduces blood viscosity, improve micro- Circulation and intestinal mucosa blood supply promote ulcer surface healing.Fang Zhong, the strong fortune tonifying spleen of Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Alba purging the liver of pathogenic fire wood during dried orange peel qi-regulating is waken up, are prevented Wind dissipates the easypro spleen of liver, and the coptis, five accompany son to have antimicrobial efficiency from modern medical analysis, there is the antibacterial and sterilization work that bright company is aobvious With.Coptis heat-clearing and damp-drying drug, relieving diarrhea with astringents;Chinese gall can inhibit the growth of various bacteria containing the soft acid of grass, and can make mucous membrane and burst Ulcer histone solidifies and shows to restrain, and hemostasis reduces exudation, and anti-inflammatory analgesic effect can protect ulcer surface, mucous membrane is promoted to repair It is multiple.Radix Salviae Miltiorrhizae activating microcirculation and removing stasis medicinal, can inhibit microvascular corrosion cast, to reduce blood viscosity, improves microcirculation and intestines filter membrane blood supply promotees It heals into ulcer.Hairyvein agrimony can shrink peripheral vessels, cooling blood and hemostasis.Alum corruption hygroscopic, antibacterial removing toxic substances effectively reduce inflammatory The exudation of secretion.All medicine phases 5, clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, hemostasis convergence, life go rotten good effect, to colonal erosion and Ulcer truly has good effect.
Through modern medicine study: cooling blood and hemostasis of the present invention, coordination of cold and heat, clearing heat and detoxicating, convergence and dysentery, relieving pain by regulating middle-JIAO are rushed down Liver tonifying spleen, activating microcirculation and removing stasis medicinal, astringing to arrest bleeding, life go corruption, restore intestinal mucosa, and repairing ulcer face inhibits microvascular corrosion cast, reduce blood Liquid viscosity improves microcirculation and intestinal mucosa blood supply, promotes ulcer surface healing.
1, Normal Physiological Function has no toxic side effect without influence or little.
2, effect is non-specific and wide spectrum.
3, there are adjusting physiological action, cooling blood and hemostasis, coordination of cold and heat, clearing heat and detoxicating, convergence and dysentery, relieving pain by regulating middle-JIAO, purging the liver of pathogenic fire is mended Spleen, activating microcirculation and removing stasis medicinal, astringing to arrest bleeding, life go corruption, improve microcirculation and intestinal mucosa blood supply, promote ulcer surface healing.
4, it can be obviously improved the clinical sign of patient, restore ulcerative colitis reparation and mitigate rehabilitation.
Specific implementation method:
The present invention is further explained in the light of specific embodiments:
It takes: coptis 10g, Radix Paeoniae Alba 15g, radix saposhnikoviae 12g, Chinese gall 15g, Rhizoma Atractylodis Macrocephalae 15g, hairyvein agrimony 15g, alum 10g, dried orange peel 5g, Radix Salviae Miltiorrhizae 18g, the totally 9 selected drying of taste Chinese medicine carry out crushed 120 meshes, water is mixed after wherein three taste Chinese medicines process For suppository (6g), once in the morning and once at night, each 6g, anus sterilization is put into rectum, and surrounding is as a treatment course.
1, as claim: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Rhizoma Atractylodis Macrocephalae: frying white Honey wheat bran is sprinkled into hot pot by art, and bighead atractylodes rhizome piece is added when smoldering, and is fried to coke yellow, is escaped burnt odor gas, takes out, weed out honey Process wheat bran.Every 100kg bighead atractylodes rhizome piece, with honey wheat bran 10kg.
2, as claim: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Radix Paeoniae Alba: take volt Imperial liver fine powder is set in pot, is made popular with moderate heat, and example, which enters, fries surface by Radix Paeoniae Alba and hang ashen, and when micro- aobvious coke yellow takes out, and weeds out native powder and puts It is cool.
3, as claim: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Radix Salviae Miltiorrhizae: removing The residual stem of impurity is cleaned, is moisturized, shave, dry.
4, the totally 9 selected drying of taste Chinese medicine of the three taste Chinese medicines including above-mentioned processing crushed after processing to wherein three tastes 120 meshes, water are mixed as pill (6g), and once in the morning and once at night, each 6g, anus sterilization is put into rectum, and surrounding is as a treatment course.
Its clinical observation 420 of the invention, anus internal plug are taken a kind of the clinical of the medicine pill patient of colonic ulcer bolt and are seen It examines, that is, has short term effect, also see that the curative effect of healing at a specified future date is 380 total, still there are 26 to be clearly better, it is invalid 14, total effective Rate is 96%.
Typical case:
Zhang: female, 50 years old, first visit on March 15 in 2014, prolonged illness face, dry mouth with bitter taste, spiritlessness and weakness, arteries and veins was fine and smooth, tongue fur Micro- Huang.Endoscopic findings, into mirror to terminal ileum: the visible multiple sheet festers of ileocaecal sphineter mucous membrane, the attached purulence tongue fur in surface.Terminal ileum It can be seen that multiple petechial hemorrhages.The visible scattered strip of sheet congestion and edema of proctosigmoid mucous membrane, the visible sheet of part mucous membrane are rotten to the corn.Through A kind of medicine pill of the anus internal plug with colonic ulcer bolt, the treatment through four courses for the treatment of, erosion disappear and are cured entirely.
Congratulate certain: female, 60 years old, first visit on May 20 in 2015, face dolorosa, lustreless complexion was thin, abdominal pain diarrhea, and arteries and veins is thin It is micro-, thick greasy tongue coating.Endoscopic findings, into mirror to terminal ileum, ileocaecal sphineter is in lip shape, appendix hole ovum circular.Terminal ileum is visible to be dissipated In multiple sheet ulcer, the white tongue fur of the attached purulence in surface, the visible petechial hemorrhage in periphery.Rectum, sigmoid colon mucosa is visible to be dispersed in strip of sheet Congestion and edema, part mucous membrane visible point sheet is rotten to the corn, and vascular lake is smudgy, and bowel bag is irregular, remaining intestinal segment no abnormality seen.Through A kind of medicine pill of the anus internal plug with colonic ulcer bolt, the treatment through five courses for the treatment of, rotten to the corn, ulcer disappear in pairs and are cured.

Claims (4)

1. a kind of medicine pill of colonic ulcer bolt.It is characterized in that the weight of prescription compatibility and various medicines are as follows: coptis 10g, white Chinese herbaceous peony 15g, radix saposhnikoviae 12g, Chinese gall 15g, Rhizoma Atractylodis Macrocephalae 15g, hairyvein agrimony 15g, alum 10g, dried orange peel 5g, Radix Salviae Miltiorrhizae 18g, totally 9 taste Chinese medicine.
2. as claim 1: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Rhizoma Atractylodis Macrocephalae: rhizoma atractylodis macrocephalae, Honey wheat bran is sprinkled into hot pot, bighead atractylodes rhizome piece is added when smoldering, fries to coke yellow, escapes burnt odor gas, take out, weeds out honey toast bran Skin.Every 100kg bighead atractylodes rhizome piece, with honey wheat bran 10kg.
3. as claim 2: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Radix Paeoniae Alba: take Fu Long Liver fine powder is set in pot, is made popular with moderate heat, and example, which enters, fries surface by Radix Paeoniae Alba and hang ashen, and when micro- aobvious coke yellow takes out, and weeds out native powder and cools.
4. as claim 3: described in a kind of medicine pill of colonic ulcer bolt, it is characterised in that the processing to Radix Salviae Miltiorrhizae: removing impurity elimination The residual stem of matter is cleaned, is moisturized, shave, dry.
CN201710425364.8A 2017-06-07 2017-06-07 A kind of medicine pill of colonic ulcer bolt Pending CN108992521A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732652A (en) * 2010-01-29 2010-06-16 阮时宝 Chinese patent medicament for treating ulcerative colitis
CN102085252A (en) * 2011-01-21 2011-06-08 中国人民解放军第二军医大学 Pharmaceutical composition for treating ulcerative colitis and colon-targeted micro-pill preparation thereof
CN106237090A (en) * 2016-08-26 2016-12-21 王冬梅 A kind of coloclysis Chinese medicine composition treating ulcerative colitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732652A (en) * 2010-01-29 2010-06-16 阮时宝 Chinese patent medicament for treating ulcerative colitis
CN102085252A (en) * 2011-01-21 2011-06-08 中国人民解放军第二军医大学 Pharmaceutical composition for treating ulcerative colitis and colon-targeted micro-pill preparation thereof
CN106237090A (en) * 2016-08-26 2016-12-21 王冬梅 A kind of coloclysis Chinese medicine composition treating ulcerative colitis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
卢进宝等: "舒肝理肠汤治疗溃疡性结肠炎42例", 《临床医学》 *
段永强等: "痛泻二草方对肝郁脾虚型UC模型大鼠的防治及作用机制研究", 《中国中医基础医学杂志》 *

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Application publication date: 20181214