CN1062167C - Hepatitis curing medicine - Google Patents

Abstract

The present invention relates to a medicine for treating hepatopathy, which is a traditional Chinese medicine preparation. The medicine is characterized in that the medicine is prepared by processing American ginseng, Chinese caterpillar fungus, Chinese yam, astragalus root, panax notoginseng, white atractylodes rhizome, etc. The medicine has the action of benefiting qi, nourishing yin, strengthening the spleen, nourishing the liver, invigorating the kidney, promoting blood circulation to disperse blood stasis and conditioning Yin and Yang of human bodies. The medicine is mainly in the preparation forms of medicinal powder, capsules or honeyed boluses. The medicine has the advantages of scientific and unique formula, easy obtainment of raw materials, simple and convenient preparation and definite therapeutic effect. The effective rate of the medicine on patients with hepatitis B is more than 90%, and the cure rate is more than 40%. The medicine also has a good therapeutic effect on hepatitis B germ carriers, early hepatic cirrhosis, active persistent hepatitis, etc.

Description

A kind of medicine for the treatment of hepatitis B

The present invention relates to a kind of medicine based on the treatment hepatitis B, is a kind of new Chinese patent medicine.

According to incompletely statistics, present national HBsAg carrier has exceeded more than 100,000,000 people, and average annual growth hepatitis B patient is no less than 1,000,000, annual about 300,000 people because of hepatopathy death, and wherein 50% is primary hepatocarcinoma.And the HBsAg positive, especially HBeAg are positive closely related again with liver cirrhosis and hepatocarcinoma, so a lot of patient is nervous, seek medical advice and medicine everywhere.The medicine of all kinds of treatment hepatitis B that present national official approval is produced has certain effect to the treatment hepatitis B, but effect instability mostly, and some should not be taken for a long time.All kinds of medical institutions and do not have the card itinerant doctor to treat the advertisement of hepatitis B multifarious, hard to tell whether it is true or false in the society make the patient be difficult to follow, and a lot of people have dust thrown into the eyes.Because hepatitis B does not still have special effect medicine therapeutic at present, so the research in this field becomes global focus.

Both at home and abroad to the Drug therapy of hepatitis B, following measure is arranged at present:

1, the application of antiviral drugs, as vidarabine, vidarabine phosphate, interferon, polyinosini etc.

2, the application of immunological enhancement medicine is as specificity anti-hepatitis B immune ribonucleic acid, thymosin, transfer factor.

3, the application of anti-hepatis B immunoglobulin and Hepatitis B virus vaccine.

4, the clinical practice of immunosuppressant is as adrenocortical hormone, glycyrrhizin tablet.

5, protect the liver and press down the enzyme medicine, as bifendate, Herba Sedi and JINGCHUI CHONGJI, oleanolic acid tablet, Radix Sophorae Tonkinensis, Lu Su, Herba Abri, Herba Silybi mariani, compound Salviae Miltiorrhizae etc. recklessly.

Said medicine such as Ah bran's adenosine, vidarabine phosphate have certain side effect, use the Chinese patent medicine of more treatment hepatitis B that YIGANNING CHONGJI, hepatitis B detoxifying capsule, hepatitis B strengthening capsule etc. are arranged at present.New medicine still constantly occurs,, compound recipe Liver Nourishing Pill grand as YIGANCAO, YIGANBAO, YUGAN dragon, sharp liver etc.

1, YIGANNING CHONGJI is formed tool regulating QI spleen invigorating, nourishing the kidney and liver, function of gallbladder promoting heat clearing away, blood circulation invigorating efficacies by the Radix Astragali, capillary wormwood, Radix Ginseng, Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Poria, the Radix Paeoniae Alba etc.; Be used for hepatitis B virus antigen positive person, acute hepatitis is also had certain curative effect.

2, the Main Ingredients and Appearance of detoxication of hepatitis B glue poison is Placenta Hominis, Rhizoma Picrorhizae, Rhizoma Osmundae, Radix Scutellariae etc., and its function is heat-clearing and toxic substances removing, liver heat removing function of gallbladder promoting, cures mainly the patient of dialectical genus dampness-heat in the liver and gallbladder.

3, the Main Ingredients and Appearance of hepatitis B strengthening capsule is Radix Ginseng, Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Rhizoma Polygoni Cuspidati, Cortex Cinnamomi etc.Tool invigorating the liver and kidney, benefiting QI for activating blood circulation, antiviral, strengthening vital QI to eliminate pathogenic factors effect are used for acute and chronic hepatitis B and hepatitis B virus carriers, dialectically belong to Liver and kidney two deficient syndrome marquis persons.

The object of the present invention is to provide the remedies for liver diseases of a kind of supplementing QI and nourishing YIN, spleen invigorating nourishing liver and kidney, blood circulation promoting and blood stasis dispelling, conditioning human yin-yang.

Technical solution of the present invention is based on pathogenetic understanding and the rule of treatment of motherland's medical science to hepatopathy, inherit ancestor's instruction by Shaodong County distinguished veteran doctors of TCM Yin as if the scholar attending doctor, clinical experience according to oneself four more than ten years, hike and doctor trained in Western medicine Yin Xuanyi cooperation by pharmacist Yin, repetition test, the selected multiple rare Chinese medicine evident in efficacy to hepatopathy, utilization tradition or modern processing method produce preparation.This medicament can suppress or kill hepatitis B virus, and the human body immunity improving function promotes liver cell regeneration and resurrection, and hepatitis B virus e antigen and surface antigen sun are turned out cloudy., hepatitis B patient, hepatitis B virus carriers early stage liver cirrhosis, activeness chronic persistent hepatitis are also had better effects.

The present invention is the medicament of being made by following key component (weight portion)

Radix Panacis Quinquefolii 1-2 part Cordyceps 1-2 part Rhizomadioscoreae 1-4 part Semen Cuscutae 1-2 part

Radix Astragali 1.5-3.5 part Typhonium flagelliforme (Lodd.) Blume 1-2 part Rhizoma Atractylodis Macrocephalae 1-4 part

Motherland's medical science is thought, the human body cause illness fundamentally sees, is yin and yang qi and blood disorder, and we adopt Radix Panacis Quinquefolii, Radix Astragali supplementing QI and nourishing YIN, the YIN and YANG balance regulating QI and blood, thus reach the purpose of improving hepatopath's allomeric function.On the other hand, liver and spleen, kidney concern the closest.Liver and spleen are the relations of catharsis and fortuneization, and The spleen has the function to transport and transform nutrients must be through the catharsis of liver, and dysfunction of the spleen in transportation influences the function of liver conversely, thus the spleen invigorating in the ban of treatment hepatopathy, we's employing Rhizoma Atractylodis Macrocephalae, Rhizomadioscoreae spleen invigorating liver nourishing.Liver and kidney are the relations of nourishing mutually, and the liver belonging to wood, kidney belong to water, and kidney water can nourish edema with the liver involved, and the material source of kidney yang kidney yin needs the catharsis of liver to be hidden in kidney again, so cry " The liver and the kidney have a common source ", takes Liver and kidney to rule together during treatment, Cordyceps, Semen Cuscutae nourishing the liver and kidney in the side.Liver blood for a long time imbalance is supported, venation block, must blood stasis in work (thrombosis in the hepatocyte inflammatory swelling, liver), Typhonium flagelliforme (Lodd.) Blume blood circulation promoting and blood stasis dispelling in the side is removed pathogenic factor.

Modern pharmacological research thinks that Radix Ginseng (Radix Panacis Quinquefolii) has to improve to be digested and assimilated and metabolic function, and the energy appetite stimulator improves the resistance of body to various destructive stimuluses, makes the pathological change trend and even recovers normal.The Radix Astragali, the Rhizoma Atractylodis Macrocephalae have the liver protecting, prevent the effect that hepatic glycogen reduces.Radix Notoginseng, Rhizomadioscoreae have antivirus action.According to another report, the Radix Astragali, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae possess immunoregulation effect, and wherein the Radix Astragali, Radix Ginseng, the Rhizoma Atractylodis Macrocephalae have the T of enhancing cell function, and Semen Cuscutae has the B cell function, can improve immunoglobulin, can also promote lymphocyte transformation; The Radix Astragali, Rhizomadioscoreae can suppress and remove HBV (hepatitis B virus).Cordyceps has the phagocytic function that improves body monokaryon-macrophage, can strengthen cytophagous activate the phagocytic capacity, and to treatment hepatitis B, constitutional (and transitivity) hepatocarcinoma, effect is better.Radix Notoginseng has the raising plasma albumin, reduces plasma globulin level, corrects albumin and the inverted effect of globulin ratio.

A key character of the present invention is that we can not only make hepatitis B patient or hepatitis B virus carriers HBsAg, HBeAg sun turn out cloudy, and can prevent that hepatitis B from transforming to liver cirrhosis, also early stage liver cirrhosis, activeness chronic persistent hepatitis is had certain curative effect.Can play a role in health care to the deficiency of vital energy, the deficiency of YIN, deficiency of the liver and kindey patient, prevent sick generations such as hepatitis B.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, our medicine is to set upright, and selected medicine all has no side effect, and the suitable chronic viral hepatitis B patient who has a delicate constitution takes for a long time.Good effect, effective percentage is more than 90%.Sun is turned out cloudy more than 50%.

2, this product therapeutic dosage forms has embodied the traditional characteristics of Chinese medicine at present based on powder, has kept former explosive component, and raw material sources are extensive, gets material easily, and processing and storage is convenient, has reduced the medicine cost, has alleviated patient's financial burden.

Method for making: get the Radix Panacis Quinquefolii 200 gram Cordyceps 200 gram Radix Notoginseng 100 gram Radixs Astragali 200 grams

The Rhizomadioscoreae 200 gram Rhizoma Atractylodis Macrocephalaes 200 gram Semen Cuscutae 200 grams

Each medicine levigation is mixed, and after the sterilization, every pouch dress 3g is the powder finished product, temporarily name " the liver benefiting treasured ".

As make capsule, extract extractum with the Radix Astragali, Rhizomadioscoreae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae earlier, again with Cordyceps, Radix Notoginseng, the former powder mixing granulation of Radix Panacis Quinquefolii, after high-temperature sterilization, with 0～No. 2 capsule fill.

The instructions of taking that marks in the packing of product is: obey every day 2 times, the morning or the morning are steamed clothes with egg, and be taken after being infused in hot water or decoction with Sugar water evening.Avoid the unclean thing of pungent, rotten wet goods.Efficacy analysis:

Now with since 95 years, Yin Ruoru, Yin Xuanyi do one Shaodong County Liu Ze commune hospital out-patient department utilization " the liver benefiting treasured " treatment 96 routine patients and tentatively sum up.

Patient age the maximum 52 years old, reckling 6 years old, 6-10 year 32 people wherein, 10-20 year 28 people, 20-40 year 32 people, 50-60 year 4 people.Wherein male 50 people, women 46 people.The clothes the liver benefiting is precious sooner or later respectively once, each 3g, 3 months per courses of treatment.

Name of disease	Case	Average medicine time	Therapeutic outcome			Remarks
							Effectively	Cure	Invalid
			Hepatitis B	64	Two courses of treatment					30	34		Curative effect judging standard: 1. and clinical symptom disappearance two half is checked normally, and liver function recovery is normally for curing; 2. subjective symptoms is improved, liver function recovery, and hepatitis B surface antigen titre obviously reduction person place is effectively; 3. subjective symptoms improve but liver function and two and half check do not have obviously change into invalid
The activeness viral hepatitis	9	Three courses of treatment				4	5
			Hepatitis B bacillicarrier	15	A course of treatment				0	11	4
The early stage liver cirrhosis chronic persistent hepatitis	4 4	Three courses of treatment of three courses of treatment				3 3	1 1					Cooperate the treatment of Chinese medicine decoction medicine typing

According to last table statistics, the precious therapeutic effect of the liver benefiting; Hepatitis B effective percentage 100%, cure rate 53.13%, active hepatitis effective percentage 100%, cure rate 55.56%, HBV bacillicarrier cure rate 73%.

Case is introduced: Wang Le, the woman 11 years old, lives in Liu Ze township, Shaodong County, Hunan Province two Xing Cun.The private prosecution fatigue and weak, appetite is poor, and disease meeting order is yellow slightly, white and thin fur, light red tongue is fat.Hospital's chemical examination in April nineteen ninety-five: HBsAg (+), HBeAg (+), anti--HBc (+), the third paddy transaminase, 156 units, thymol turbidity 12 units.Take 2 courses of treatment of medicine of the present invention " the liver benefiting treasured " (3 months per courses of treatment), check October in the same year: " three big sun ' ' all to turn out cloudy, clinical symptom disappearance is followed up a case by regular visits to and is not seen recurrence.

Claims (4)

1, a kind of medicine for the treatment of hepatitis B is characterized in that it is the medicament of being made by the following weight proportion raw material:

Radix Panacis Quinquefolii 1-2 part Cordyceps 1-2 part Rhizomadioscoreae 1-4 part

2 parts of Radix Astragali 1.5-3.5 part Typhonium flagelliforme (Lodd.) Blume 1-2 part Rhizoma Atractylodis Macrocephalae 1-4 part Semen Cuscutae.

2, the medicine of treatment hepatitis B according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 parts of Rhizomadioscoreae of 2 parts of Cordyceps of Radix Panacis Quinquefolii

2 parts of 2 parts of Semen Cuscutae of 1 part of Rhizoma Atractylodis Macrocephalae of 2 parts of Typhonium flagelliforme (Lodd.) Blume of the Radix Astragali.

3, the medicine of treatment hepatitis B according to claim 1 is characterized in that said medicament is a said dosage form on any pharmaceutics.

4, the medicine of treatment hepatitis B according to claim 3 is characterized in that said medicament is powder or capsule.