CN106215100A - A kind of Chinese medicine composition preventing and treating poultry pericardial effusion hepatitis syndrome and its preparation method and application - Google Patents
A kind of Chinese medicine composition preventing and treating poultry pericardial effusion hepatitis syndrome and its preparation method and application Download PDFInfo
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- CN106215100A CN106215100A CN201610698972.1A CN201610698972A CN106215100A CN 106215100 A CN106215100 A CN 106215100A CN 201610698972 A CN201610698972 A CN 201610698972A CN 106215100 A CN106215100 A CN 106215100A
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Abstract
The present invention provides a kind of Chinese medicine composition preventing and treating poultry pericardial effusion hepatitis syndrome, described Chinese medicine composition is made up of each crude drug of following weight portion: Ramulus Cinnamomi 10 20 parts, Pollen Typhae 20 30 parts, 15 25 parts of Rhizoma Curcumae Longae, 15 25 parts of Semen Persicae, Radix Paeoniae Rubra 10 30 parts, Rhizoma Alismatis 10 30 parts, Radix Curcumae 10 30 parts, Fructus Aurantii Immaturus 10 25 parts, the Rhizoma Atractylodis Macrocephalae 10 30 parts.The present invention also provides for its preparation method and application.The Chinese medicine composition of the present invention has effect of warming YANG activating QI, invigorating the spleen to clear away damp pathogen, blood circulation promoting and blood stasis dispelling, peace and the five internal organs, and poultry pericardial effusion hepatitis syndrome can be effectively treated in clinical practice.
Description
Technical field
The invention belongs to veterinary drug technical field, be specifically related to a kind of Chinese medicine preventing and treating poultry pericardial effusion-hepatitis syndrome
Compositions.
Background technology
Pericardial effusion hepatitis syndrome (also known as " Ankara is sick ") is that the one caused by serum 4 type aviadenovirus is novel
Poultry disease.Classical symptom is 3-5 week old broiler sudden death, and is attended by hydropericardium and hepatitis, therefore gains the name.Peace
OK a karaoke club disease is propagated with pollutant horizontal transmission and contact between broiler group mechanically.Primary disease with horizontal transmission is mainly
Main, spread speed is fast；Broiler, hybrid meat chicken, partridge chickens and young chicken are multiple, and each kind chicken all has morbidity.Morbidity age in days, 15-
70 ages in days are multiple, the earliest visible 6 age in days morbidities, and the laying hen of age in days more than 300 also falls ill.Sickness rate, mortality rate and morbidity age in days, raise
Supporting environment etc. and have relatively Important Relations, the most early, mortality rate is the highest, even can be annihilated for morbidity age in days, if during morbidity and salmonella
During the mixed infections such as disease, colibacillosis, chronic respiratory tract disease, bird flu, newcastle, then mortality rate increases considerably.
At present, Ankara is sick temporarily without effective therapeutic scheme, and antiviral effect is undesirable.Clinically with the liver infected
Oneself Formalin inactivation Seedling of dirty homogenate preparation can reduce mortality rate and be employed in prevention.It is used in Embryo Gallus domesticus liver cell
Vaccine prepared by the cell culture of growth virus also can produce protection.Patent of invention (201610120162.8) relates to one
Anti-Ankara chicken yolk antibody, this method needs to be furtherd investigate further.Tradition veterinary thinks that primary disease system is that ferritic is weak,
Taste are not good for, and feel exopathogen again, and in then causing, spleen sun is impaired, transformation failure of spleen, cause retention of water-damp in the body, the icepro heart waterborne, and heart-fire does not drops,
Kidney water does not rises, the kidney failing to nourish the liver, causes lesions of liver and kidney.Containing in damp, involve in lung, lung qi must not declare fall, and causes cough with asthma.It is the most sick
Machine is insufficiency of the spleen leading to overabundance of dampness, and damp is violated.Control suitable wet fortune middle-jiao yang, function of the spleen and stomach, invigorating the spleen to clear away damp pathogen.
Summary of the invention
The technical problem to be solved in the present invention is to overcome existing defect, it is provided that one can effectively prevent and treat poultry pericardium
The Chinese medicine composition of hydrops hepatitis syndrome；To this end, the present invention also provides for its preparation method and application.
First purpose of the present invention is to provide a kind of Chinese medicine composition preventing and treating poultry pericardial effusion-hepatitis syndrome,
Described Chinese medicine composition is made up of each crude drug of following weight portion: Ramulus Cinnamomi 10-20 part, Pollen Typhae 20-30 part, Rhizoma Curcumae Longae 15-25 part,
Semen Persicae 15-25 part, Radix Paeoniae Rubra 10-30 part, Rhizoma Alismatis 10-30 part, Radix Curcumae 10-30 part, Fructus Aurantii Immaturus 10-25 part, Rhizoma Atractylodis Macrocephalae 10-30 part.
As preferably, described Chinese medicine composition is made up of each crude drug of following weight portion: Ramulus Cinnamomi 15 parts, Pollen Typhae 25 parts,
25 parts of Rhizoma Curcumae Longae, 15 parts of Semen Persicae, Radix Paeoniae Rubra 10 parts, Rhizoma Alismatis 15 parts, Radix Curcumae 15 parts, Fructus Aurantii Immaturus 25 parts, the Rhizoma Atractylodis Macrocephalae 10 parts.
The now best results of the preventing and treating poultry intestinal poison syndrome of the Chinese medicine composition of the present invention.
The present invention preventing and treating poultry pericardial effusion-hepatitis syndrome Chinese medicine composition in the preparation, generally above-mentioned heavy
Excipient is added outside the Chinese medicine ingredients of amount part, such as solid carrier, anticaking agents, antifungus agent and correctives etc., and can basis
Conventional formulation method, uses after being prepared as the dosage forms such as powder, extractum powder and granule.This of the pharmaceutical composition of the present invention
Kind preparation preferably comprises the ingredient of aforementioned proportion part of the most about 10%-100% as effective ingredient.
Example as the solid carrier of excipient includes sucrose, starch, dextrin, cellulose derivative etc..
Example as anticaking agents includes silicon dioxide, calcium stearate, glyceryl monostearate and tricalcium phosphate etc..
Example as antifungus agent includes potassium sorbate, sodium diacetate and sodium bicarbonate etc..
Example as correctives includes glycine, saccharin sodium, saccharin sodium, sodium glutamate, 5'-GMP2Na and food
Product spice etc..
Second object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition, be by Ramulus Cinnamomi, Pollen Typhae, Rhizoma Curcumae Longae,
Semen Persicae, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add the pure of 10-12 times of medical material weight every time
Change water, decoct 1 hour every time, filter, merging filtrate, obtain oral liquid；
As preferably, concentrating filtrate after merging filtrate, described concentration is for being concentrated into every 1mL 1g Han primary crude drug；
As preferably, add antifungus agent and correctives mixing after concentration.
Third object of the present invention is to provide another preparation method of above-mentioned Chinese medicine composition, be by Ramulus Cinnamomi, Pollen Typhae,
Rhizoma Curcumae Longae, Semen Persicae, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add 10-12 times of medical material weight every time
Purified water, decoct 1 hour every time, filter, merging filtrate, concentrated spray dry, pulverize, and obtains extractum powder；
As preferably, described concentration is to be concentrated into relative density to 1.31-1.35(50-55 DEG C) thick paste；
As preferably, after being spray-dried pulverizing, add anticaking agents and draw humectant with anti-.
Fourth object of the present invention is to provide another preparation method of above-mentioned Chinese medicine composition, be by Ramulus Cinnamomi, Pollen Typhae,
Rhizoma Curcumae Longae, Semen Persicae, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add every time, 10-12 times of medical material weight
The purified water of amount, decocts 1 hour every time, filters, merging filtrate, concentrates, adds adjuvant, make granule, is dried, granulate, obtains
Granule；
As preferably, described concentration is to be concentrated into relative density to be 1.31-1.35(50-55 DEG C) thick paste；
As preferably, described adjuvant is soluble starch, sucrose or lactose.
It is comprehensive in preparation preventing and treating poultry pericardial effusion-hepatitis that 5th purpose of the present invention is to provide above-mentioned Chinese medicine composition
Application in the medicine levied.
6th purpose of the present invention is to provide a kind of medicine, and the effective ingredient of described medicine is described in claim 1 or 2
Chinese medicine composition.
As preferably, described medicine also includes medically acceptable adjuvant.
As preferably, in described medicine, the weight/mass percentage composition of effective ingredient is 10%-100%.
The pharmaceutical composition of the present invention is special for " insufficiency of the spleen leading to overabundance of dampness is violated in damp " pathogenesis of pericardial effusion-hepatitis syndrome
Point, selects Ramulus Cinnamomi warming YANG activating QI, making the adverse-rising QI downwards；Rhizoma Alismatis promoting diuresis with drugs of tasteless flavour, closes Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae and strengthening the spleen to promote digestion, and regulating qi to disperse stagnation is turbid；Pu
Huang, Rhizoma Curcumae Longae, Radix Curcumae, Radix Paeoniae Rubra blood circulation promoting and blood stasis dispelling, liver-smoothing, qi-regulating, nurse one's health conscience function；Semen Persicae lung qi dispersing, only cough with dyspnea, all medicines share,
Warming YANG activating QI, invigorating the spleen to clear away damp pathogen, blood circulation promoting and blood stasis dispelling, peace and the five internal organs, so poultry pericardial effusion-hepatitis syndrome can effectively be treated.
Detailed description of the invention
Below example facilitates a better understanding of the present invention, but does not limit the present invention.Experiment in following embodiment
Method, if no special instructions, is conventional method.Test material used in following embodiment, if no special instructions, is city
Sell.
The Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is by each raw material of following mass fraction
Medicine forms:
Ramulus Cinnamomi 10-20 part, Pollen Typhae 20-30 part, Rhizoma Curcumae Longae 15-25 part, Semen Persicae 15-25 part, Radix Paeoniae Rubra 10-30 part, Rhizoma Alismatis 10-30 part,
Radix Curcumae 10-30 part, Fructus Aurantii Immaturus 10-25 part, Rhizoma Atractylodis Macrocephalae 10-30 part.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
Ramulus Cinnamomi, Pollen Typhae, Rhizoma Curcumae Longae, Semen Persicae, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decocts three times, add every time
Enter the purified water of 10-12 times of medical material weight, decoct 1 hour every time, filter, merging filtrate, concentrate, according to this area conventional formulation
Method carries out post processing, obtains final preparation type (such as oral liquid, granule or extractum powder etc.).
Embodiment 1
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 10g, Pollen Typhae 20g, Rhizoma Curcumae Longae 15g, Semen Persicae 25g, Radix Paeoniae Rubra 30g, Rhizoma Alismatis 10g, Radix Curcumae 10g, Fructus Aurantii Immaturus 10g, Rhizoma Atractylodis Macrocephalae 20g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 10g, Pollen Typhae 20g, Rhizoma Curcumae Longae 15g, Semen Persicae 25g, Radix Paeoniae Rubra 30g, Rhizoma Alismatis 10g, Radix Curcumae 10g, trifoliate orange
Real 10g, Rhizoma Atractylodis Macrocephalae 20g, after clean remove impurity processed, decoct three times, add the purified water of 10-12 times of medical material weight every time, decocts 1 little every time
Time, filter, merging filtrate, be concentrated into every 1mL 1g Han primary crude drug, add antifungus agent and correctives, mixing, obtain for preventing and treating
The Chinese medicine composition oral liquid of poultry pericardial effusion-hepatitis syndrome.
Embodiment 2
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 150g, Pollen Typhae 250g, Rhizoma Curcumae Longae 250g, Semen Persicae 150g, Radix Paeoniae Rubra 100g, Rhizoma Alismatis 150g, Radix Curcumae 150g, Fructus Aurantii Immaturus 250g,
Rhizoma Atractylodis Macrocephalae 100g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 150g, Pollen Typhae 250g, Rhizoma Curcumae Longae 250g, Semen Persicae 150g, Radix Paeoniae Rubra 100g, Rhizoma Alismatis 150g, Radix Curcumae
150g, Fructus Aurantii Immaturus 250g, Rhizoma Atractylodis Macrocephalae 100g, after clean remove impurity processed, decoct three times, adds the purified water of 8-10 times of medical material weight, often every time
Secondary decoction 1 hour, filters, merging filtrate, uses conventional method to be concentrated into relative density and be 1.31-1.35(50-55 DEG C) thick
Cream, is spray-dried, and pulverizes, and adds appropriate anticaking agents, anti-draws humectant etc., mixes and i.e. obtain for preventing and treating poultry pericardial effusion liver
The Chinese medicine composition extractum powder of scorching syndrome.
Embodiment 3
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 15g, Pollen Typhae 25g, Rhizoma Curcumae Longae 25g, Semen Persicae 15g, Radix Paeoniae Rubra 10g, Rhizoma Alismatis 15g, Radix Curcumae 15g, Fructus Aurantii Immaturus 25g, Rhizoma Atractylodis Macrocephalae 10g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 15g, Pollen Typhae 25g, Rhizoma Curcumae Longae 25g, Semen Persicae 15g, Radix Paeoniae Rubra 10g, Rhizoma Alismatis 15g, Radix Curcumae 15g, trifoliate orange
Real 25g, Rhizoma Atractylodis Macrocephalae 10g, after clean remove impurity processed, decoct three times, add the purified water of 8-10 times of medical material weight every time, decocts 1 little every time
Time, filter, merging filtrate, use conventional method to be concentrated into relative density and be 1.31-1.35(50-55 DEG C) thick paste, add appropriate
Adjuvant, such as soluble starch, cane sugar powder, lactose etc., makes granule, is dried, granulate, mix i.e. obtain for preventing and treating poultry pericardium long-pending
The Chinese medicinal composition granules of liquid hepatitis syndrome.
Embodiment 4
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 150g, Pollen Typhae 250g, Rhizoma Curcumae Longae 250g, Semen Persicae 150g, Radix Paeoniae Rubra 100g, Rhizoma Alismatis 150g, Radix Curcumae 150g, Fructus Aurantii Immaturus 250g,
Rhizoma Atractylodis Macrocephalae 100g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 150g, Pollen Typhae 250g, Rhizoma Curcumae Longae 250g, Semen Persicae 150g, Radix Paeoniae Rubra 100g, Rhizoma Alismatis 150g, Radix Curcumae
150g, Fructus Aurantii Immaturus 250g, Rhizoma Atractylodis Macrocephalae 100g, after clean remove impurity processed, decoct three times, adds the purified water of 10-12 times of medical material weight, often every time
Secondary decoction 1 hour, filters, merging filtrate, is concentrated into every 1mL 1g Han primary crude drug, adds antifungus agent and correctives, mixes, i.e.
Must be used for preventing and treating the Chinese medicine composition oral liquid of poultry pericardial effusion-hepatitis syndrome.
Embodiment 5
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 20g, Pollen Typhae 30g, Rhizoma Curcumae Longae 20g, Semen Persicae 20g, Radix Paeoniae Rubra 20g, Rhizoma Alismatis 30g, Radix Curcumae 20g, Fructus Aurantii Immaturus 25g, Rhizoma Atractylodis Macrocephalae 30g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 20g, Pollen Typhae 30g, Rhizoma Curcumae Longae 20g, Semen Persicae 20g, Radix Paeoniae Rubra 20g, Rhizoma Alismatis 30g, Radix Curcumae 20g, trifoliate orange
Real 25g, Rhizoma Atractylodis Macrocephalae 30g, after clean remove impurity processed, decoct three times, add the purified water of 10-12 times of medical material weight every time, decocts 1 little every time
Time, filter, merging filtrate, be concentrated into every 1mL 1g Han primary crude drug, add antifungus agent and correctives, mixing, obtain for preventing and treating
The Chinese medicine composition oral liquid of poultry pericardial effusion-hepatitis syndrome.
Embodiment 6
The formula of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is as follows:
Ramulus Cinnamomi 15g, Pollen Typhae 20g, Rhizoma Curcumae Longae 15g, Semen Persicae 20g, Radix Paeoniae Rubra 20g, Rhizoma Alismatis 20g, Radix Curcumae 30g, Fructus Aurantii Immaturus 15g, Rhizoma Atractylodis Macrocephalae 30g.
The preparation method of the Chinese medicine composition of the preventing and treating poultry pericardial effusion-hepatitis syndrome of the present invention is:
In prescription ratio, weigh Ramulus Cinnamomi 15g, Pollen Typhae 20g, Rhizoma Curcumae Longae 15g, Semen Persicae 20g, Radix Paeoniae Rubra 20g, Rhizoma Alismatis 20g, Radix Curcumae 30g, trifoliate orange
Real 15g, Rhizoma Atractylodis Macrocephalae 30g, after clean remove impurity processed, decoct three times, add the purified water of 8-10 times of medical material weight every time, decocts 1 little every time
Time, filter, merging filtrate, use conventional method to be concentrated into relative density and be 1.31-1.35(50-55 DEG C) thick paste, add appropriate
Adjuvant, such as soluble starch, cane sugar powder, lactose etc., makes granule, is dried, granulate, mix i.e. obtain for preventing and treating poultry pericardium long-pending
The Chinese medicinal composition granules of liquid hepatitis syndrome.
In order to the pharmaceutical composition of the essence and the present invention that further illustrate the present invention is to poultry pericardial effusion hepatitis
The beneficial effect of syndrome, the application Chinese medicine composition (as a example by Chinese medicine composition oral liquid of the present invention) is carried out by applicant
Clinical drug trial.But those skilled in the art know, conventional according to this area with Chinese medicine composition of the present invention for effective ingredient
Poultry pericardial effusion-hepatitis syndrome all can effectively be prevented and treated by the medicine that formulation method prepares.
1) trial drug Chinese medicine composition of the present invention.
2) EXPERIMENTAL DESIGN
This test is carried out in Lanzhou Suburb Breeder hens chicken farm, chooses 70 ages in days being diagnosed as pericardial effusion hepatitis syndrome
Breeder hens is object of study, is randomly divided into 4 groups, wherein tests 1 group (embodiment 1) 150, tests 2 groups (embodiments 4) 150,
Test 3 groups (embodiments 5) 150, according to every 1kg bodyweight p Chinese medicine composition of the present invention oral liquid 0.1mL, mixed drink, every day
Once, successive administration 5 days.Matched group is composite treatment plate clear granule+Vc+ Artogicurol lactone, all gives with 0.1g/kg body weight dose
Medicine, once a day, successive administration 5 days.Other are consistent in feeding and management, observe and make a record.After first administration is treated 7 days
Statistics therapeutic effect, curative effect determinate standard is as follows:
Effectively referring to after medication first in 7 days, ill chicken spirit, recovery of searching for food, glucose recovery is normal.
After the medication first of invalid finger in 7 days, ill chicken is without taking a turn for the better, even dead.
3) data statistics
SPSS (Version 17.0) is utilized to carry out data analysis.X 2 test evaluation test group and the cure rate of matched group
And total effective rate.The difference of inspection is statistically significant all to use two-sided test, P ＜ 0.05 to think.Different tests Sets of Measurement provides
Material uses " mean ± std " to carry out statistics and describes.
4) result
The clinical effectiveness of traditional Chinese medicine composition for treating chicken pericardial effusion-hepatitis syndrome of the present invention is shown in Table 1.Compare with matched group, this
The effective percentage of invention Chinese medicine composition significantly improves, and mortality rate significantly reduces, and difference is extremely notable (P ＜ 0.01), and in the present invention
Drug composition respectively organize between without significant difference (P ＞ 0.05).Result shows, Chinese medicine composition of the present invention can effectively be treated Cor Gigeriae Galli bag and be amassed
Liquid-hepatitis syndrome.
The clinical effect trial result of table 1 Chinese medicine composition of the present invention effect treatment chicken pericardial effusion-hepatitis syndrome
Note: same column data shoulder indicate same letter person's difference notable (P＞ 0.05), the different lower case person's difference of mark shows
Write (P＜ 0.05), the different capitalization person's significant difference of mark (P＜ 0.01).
Finally it is noted that the foregoing is only the preferred embodiments of the present invention, it is not limited to the present invention,
Although being described in detail the present invention with reference to previous embodiment, for a person skilled in the art, it still may be used
So that the technical scheme described in foregoing embodiments to be modified, or wherein portion of techniques feature is carried out equivalent.
All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included in the present invention's
Within protection domain.
Claims (9)
1. the Chinese medicine composition preventing and treating poultry pericardial effusion-hepatitis syndrome, it is characterised in that: described Chinese medicine composition by
Each crude drug composition of following weight portion: Ramulus Cinnamomi 10-20 part, Pollen Typhae 20-30 part, Rhizoma Curcumae Longae 15-25 part, Semen Persicae 15-25 part, Radix Paeoniae Rubra
10-30 part, Rhizoma Alismatis 10-30 part, Radix Curcumae 10-30 part, Fructus Aurantii Immaturus 10-25 part, Rhizoma Atractylodis Macrocephalae 10-30 part.
Chinese medicine composition the most according to claim 1, it is characterised in that: described Chinese medicine composition is each by following weight portion
Crude drug forms: Ramulus Cinnamomi 15 parts, Pollen Typhae 25 parts, 25 parts of Rhizoma Curcumae Longae, 15 parts of Semen Persicae, Radix Paeoniae Rubra 10 parts, Rhizoma Alismatis 15 parts, Radix Curcumae 15 parts, trifoliate orange
Real 25 parts, the Rhizoma Atractylodis Macrocephalae 10 parts.
3. the preparation method of the Chinese medicine composition described in claim 1 or 2, it is characterised in that: it is by Ramulus Cinnamomi, Pollen Typhae, Rhizoma Curcumae Longae, Fructus Persicae
Core, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add the purification of 10-12 times of medical material weight every time
Water, decocts 1 hour every time, filters, merging filtrate, obtains oral liquid；
As preferably, concentrating filtrate after merging filtrate, described concentration is for being concentrated into every 1mL 1g Han primary crude drug；
As preferably, add antifungus agent and correctives mixing after concentration.
4. the preparation method of the Chinese medicine composition described in claim 1 or 2, it is characterised in that: it is by Ramulus Cinnamomi, Pollen Typhae, Rhizoma Curcumae Longae, Fructus Persicae
Core, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add the purification of 10-12 times of medical material weight every time
Water, decocts 1 hour every time, filters, and merging filtrate, concentrated spray dry, pulverize, and obtains extractum powder；
As preferably, described concentration is to be concentrated into relative density to 1.31-1.35(50-55 DEG C) thick paste；
As preferably, after being spray-dried pulverizing, add anticaking agents and draw humectant with anti-.
5. claim 1 or the preparation method of 2 described Chinese medicine compositions, it is characterised in that: be by Ramulus Cinnamomi, Pollen Typhae, Rhizoma Curcumae Longae,
Semen Persicae, Radix Paeoniae Rubra, Rhizoma Alismatis, Radix Curcumae, Fructus Aurantii Immaturus, the Rhizoma Atractylodis Macrocephalae are mixed by proportioning, decoct three times, add every time, 10-12 times of medical material weight pure
Change water, decoct 1 hour every time, filter, merging filtrate, concentrate, add adjuvant, make granule, be dried, granulate, obtain granule；
As preferably, described concentration is to be concentrated into relative density to be 1.31-1.35(50-55 DEG C) thick paste；
As preferably, described adjuvant is soluble starch, sucrose or lactose.
6. the Chinese medicine composition described in claim 1 or 2 is in the medicine of preparation preventing and treating poultry pericardial effusion-hepatitis syndrome
Application.
7. a medicine, it is characterised in that: the effective ingredient of described medicine is the Chinese medicine composition described in claim 1 or 2.
Medicine the most according to claim 7, it is characterised in that: described medicine also includes medically acceptable adjuvant.
9. according to the medicine described in claim 7 or 8, it is characterised in that: the weight/mass percentage composition of effective ingredient in described medicine
For 10%-100%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729707A (en) * | 2017-01-19 | 2017-05-31 | 天津市中升挑战生物科技有限公司 | A kind of composite yolk antibody for prophylactic treatment chicken hydropericardium hepatitis syndrome and preparation method thereof |
| CN113197967A (en) * | 2021-05-18 | 2021-08-03 | 山东牧王药业科技有限公司 | Traditional Chinese medicine composition for preventing and treating poultry hepatosis syndrome |
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| CN104587392A (en) * | 2015-01-09 | 2015-05-06 | 阚广宇 | Medicine for improving microcirculation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104587392A (en) * | 2015-01-09 | 2015-05-06 | 阚广宇 | Medicine for improving microcirculation |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729707A (en) * | 2017-01-19 | 2017-05-31 | 天津市中升挑战生物科技有限公司 | A kind of composite yolk antibody for prophylactic treatment chicken hydropericardium hepatitis syndrome and preparation method thereof |
| CN106729707B (en) * | 2017-01-19 | 2021-08-24 | 天津市中升挑战生物科技有限公司 | Composite yolk antibody for preventing and treating chicken pericardial effusion-hepatitis syndrome and preparation method thereof |
| CN113197967A (en) * | 2021-05-18 | 2021-08-03 | 山东牧王药业科技有限公司 | Traditional Chinese medicine composition for preventing and treating poultry hepatosis syndrome |
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Application publication date: 20161214 |
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| RJ01 | Rejection of invention patent application after publication |