CN106214545A

CN106214545A - A kind of containing natural plant extracts and synergetic effect additive fat reducing compositions

Info

Publication number: CN106214545A
Application number: CN201610704809.1A
Authority: CN
Inventors: 裴双秀; 张霞
Original assignee: Beijing Huaxin Longyue Technology Co Ltd
Current assignee: Beijing Huaxin Longyue Technology Co Ltd
Priority date: 2016-08-22
Filing date: 2016-08-22
Publication date: 2016-12-14

Abstract

The invention discloses a kind of natural plants mixture, additional synergetic effect additive and plant fat-eliminating slimming compositions of solvent composition containing one or both in Rhizoma Imperatae extract, Cortex Mori extract, by giving full play to the collaborative effect for reducing fat of synergist in compositions, greatly reduce the raw material zest to skin in cosmetics, blood fat reducing moistening effect is excellent, blood fat reducing does not rebounds, easily use, safe and effective, harmless.

Description

A kind of containing natural plant extracts and synergetic effect additive fat reducing compositions

Technical field

The present invention relates to a kind of fat reducing compositions containing natural plant extracts and synergetic effect additive, be mainly used in antagonism Athero, especially for stomach fat.

Background technology

Rhizoma Imperatae, another name: cogonsatintail, Rhizoma Imperatae, Rhizoma Imperatae, root of couch grass, for the dry rhizome of grass Herba Imperatae.Have cool Blood stops blooding, effect of clearing away heat and promoting diuresis.

Rhizoma Imperatae whole body is all medicine.Rhizoma Imperatae sweet in the mouth, cold in nature.Enter lung, stomach warp.There is effect of clearing away heat and promoting production of body fluid, cooling blood for hemostasis.Face Bed is commonly applied to calentura excessive thirst, cough due to lung-heat, bleeding due to blood-heat, acute nephritis, urinary system infection, hematuria, infantile measles, calentura The diseases such as rear excessive thirst, pyretic stranguria.Its property diuretic and non-impairment of YIN, have YIN fluid being insufficient phenomenon person especially with heat syndrome.The most applicable.Separately there is report Road, isolates Anemonin from this product, has significant antibacterial action.Staphylococcus, streptococcus, diphtheria corynebacterium etc. all there is suppression Effect.The flower of Rhizoma Imperatae has effect of hemostasis, pain relieving, it is possible to the diseases such as treatment haematemesis, knife injury.Folium Imperatae, can adopt the whole year.Containing mountain Mandarin orange alcohol etc., also have heat-clearing and toxic substances removing, expelling wind and removing dampness, removing heat from blood effect.

Cortex Mori, calls Cortex Mori, Radix Mori skin, Cortex Mori, Morus alba skin, for the dry root bark of Moraceae Mulberry plant.Micro-have Bean stink smell, sweet and slightly bitter taste, there are blood sugar lowering, diuresis, antibacterial grade acts on.

" Rhizoma Imperatae chemistry, pharmacology are inquired into clinical practice " (Jiang Lingli etc., " traditional Chinese medical science journal ", 05 phase in 2014) discloses Rhizoma Imperatae active component mainly has packet header father-in-law element；Organic acid: Palmic acid, oxalic acid, citric acid, malic acid etc.；Triterpenes: print is white Mao Su, Bai Maosu etc.；Sterols: campesterol, stigmasterol etc.；Saccharide: polysaccharide, glucose, fructose and xylose etc., containing abundant Potassium salt.Rhizoma Imperatae has hemostasis, diuresis, analgesia, antibacterial, antiinflammatory, antioxidation, blood pressure lowering, protects the liver, regulates body's immunity Deng pharmacological action.

Chinese patent CN105394279A, it is provided that a kind of Antilipemic slimming tea adding Chinese medicine, can preferably reach blood fat reducing Effect of fat-reducing.The parts by weight of various raw materials are: Radix Et Rhizoma Fagopyri Tatarici 10～50 parts, Herba Portulacae 10～20 parts, Flos dolichoris 10～20 parts, Rhizoma Zingiberis Recens Yellow 10～20 parts, Cortex Lycii 10～20 parts, Rhizoma Imperatae 10～20 parts, Poria 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Folium Nelumbinis 10～20 Part, Herba Eupatorii 10～20 parts, Herb Gynostemmae Pentaphylli 10～20 parts, Cortex Mori 10～20 parts, Fructus Corni 10～20 parts, Radix Curcumae 10～20 parts are fragrant Attached 10～20 parts, the Radix Astragali 10～20 parts, Semen Coicis 10～20 parts, the Rhizoma Atractylodis Macrocephalae 10～20 parts, Fructus Crataegi 10～20 parts, Semen Cassiae 10～20 Part.

Triglyceride is the fat constituent of human body, the decomposition of fat in food.Liver also can be by some in blood Saccharide converted for triglyceride.If triglyceride is excessive, hoards and will make body obesity in subcutaneous, hoard and then make in blood vessel wall Become arteriosclerosis, hoard and may result in cardiac hypertrophy in heart, hoard and then can cause fatty liver in liver.

Lipogenesis reason: 1, the heat taken in is more than the energy consumed；2, lack exercise, due to age or other reasons The metabolism caused declines；3, medicine, heredity, obesity in puerperal etc..

Adipose cell is the cell of fat tissue storage fat, and under normal circumstances, adipocyte count has arrived adolescence It is not further added by.The people just got fat after growing up, usually adipose cell make volume become big institute because of storage superabundant fats Cause.It is, adipose cell deformation, cause elasticity to lose and fibrosis, cause the bodily form abnormal.

Steatolysis is that fat triglyceride is degraded into glycerol and free fatty, fatty tissue metabolism in vivo and conjunction Become to there is dynamic equilibrium.Lipid mobilization refers to: fatty tissue discharges fatty acid and glycerol through the hydrolysis of lipase. Therefore, fatty tissue is decomposed into glycerol and free fatty is the first step of lipid mobilization, is also one of the key of fat-reducing.

In implementing fat-reducing, fat is not all to disappear with uniform speed in all sites, but stomach fat disappears Stall degree is faster, this is because each tissue site lipogenesis is different with the speed of steatolysis than thigh and buttocks.Especially for stupid Gu localized fat deposits, in the adipose cell of these stubbornnesses, owing to slow shifts with inert energy, and owing to steatolysis increases The free fatty adding generation is built up in intracellular, may exist in the intracellular formation with acid accumulation and inhibit steatolysis.

So in order to eliminate larger amount of triglyceride, energization shifts, and can add the most natural in the process Vegetable composition, activates the synthesis of Adipose trigtyceride lipase (ATGL: activate fat-splitting important biochemical enzymes), promotes fat Fat is mobilized to be increased, and makes adipose cell return to normal, plays the effect of fat-eliminating slimming.

The present invention is according to above-mentioned prior art, it is provided that a kind of based on natural plant extracts, additional synergetic effect additive, Solvent, does not increase expensive cosmetic material, the fat reducing natural plant composition that use cost is relatively low.

Summary of the invention

The present invention provides a kind of natural plants containing natural plant extracts, additional synergetic effect additive and solvent composition to disappear Fat Weight reducing compound, by giving full play to the collaborative effect for reducing fat of synergist in compositions, so that subcutaneous tissue swelling is disappeared, promotees Enter the synthesis of Adipose trigtyceride lipase, make adipose cell return to normal, play the effect of fat-eliminating slimming, improve fatty tissue Structure, eliminates edema, supplements the water profit of skin, and antioxygenic property is good, effect stability, greatly reduces in cosmetics raw material to skin Zest, blood fat reducing moistening effect is excellent, and blood fat reducing does not rebounds, and easily uses, safe and effective, harmless.

The fat reducing compositions of plant extract contained by the present invention and synergetic effect additive contains:

A) plant extract；

B) synergetic effect additive；

C) solvent.

A in described compositions) plant extract includes one or both in Rhizoma Imperatae extract, Cortex Mori extract Mixture.

B in described compositions) synergetic effect additive includes mannitol, 1,2-butanediol, 1,2-ethohexadiol, phenethanol, 1,2- One in pentanediol, Sensiva SC50, glycerol citrate, polydimethylsiloxane, glycerol monolaurate or at least The mixture of two kinds；

C in described compositions) solvent includes water, Herba Imperatae blade of grass aqueous extract, Herba Imperatae showy flowers of herbaceous plants aqueous extract, Rhizoma Imperatae water A kind of or the mixture of at least two in extracting solution.

Wherein, A in described compositions) weight percentage of plant extract is 1.0～30%, preferably 5～25%, More most preferably 10～20%.

B in described compositions) weight percentage of synergetic effect additive is 0.5～30%, preferably 1.0～20%.

C in described compositions) weight percentage of solvent is 5～90%, preferably 15～70%, more preferably 20～ 60%.

Milling process and CO 2 supercritical are the most typically taked in the preparation of described Rhizoma Imperatae extract/Cortex Mori extract The processing technique that extraction combines.

Production technology: through selected Rhizoma Imperatae rhizome/Cortex Mori root bark → classification → clean → sort → pulverize → add water Steaming and decocting → removal bitterness → cake → carbon dioxide supercritical fluid extraction processed → complete purification → Rhizoma Imperatae extract/Cortex Mori extract The physical methods such as → packaging → warehouse-in are produced, and without any spice or additive, and are wild or dry crop, do not have There are pesticide, chemical fertilizer and other pollutions.

Described Herba Imperatae blade of grass aqueous extract is to make to be soaked in water the solution of Rhizoma Imperatae leaf gained, preparation method: by 100% Meter, weighs the Herba Imperatae blade of grass of 10%-50%, is torn into little bar or clays into power, and adds in 50%-90% water, soaks 1-under room temperature 24 hours, then 40-100 DEG C of heating in water bath about 15 minutes, filter, take supernatant and be described Herba Imperatae blade of grass water extraction Liquid；

Described Herba Imperatae showy flowers of herbaceous plants aqueous extract is to make to be soaked in water the solution of Rhizoma Imperatae flower aqueous extract gained, preparation method: Based on 100%, weigh the Herba Imperatae showy flowers of herbaceous plants of 10%-50%, add in 50%-90% water, soak 1-24 hour under room temperature, then exist 40-100 DEG C of heating in water bath about 15 minutes, filters, takes supernatant and be described Herba Imperatae showy flowers of herbaceous plants aqueous extract；

Described Rhizoma Imperatae aqueous extract is the solution of the Rhizoma Imperatae gained making to be soaked in water fresh, preparation method: press 100% meter, weighs the Rhizoma Imperatae of 10%-50%, is cut into small pieces or clays into power, and adds in 50%-90% water, soaks under room temperature Steep 1-24 hour, then 40-100 DEG C of heating in water bath about 15 minutes, filter, take supernatant and be described Rhizoma Imperatae water and carry Take liquid.

Described natural plant composition can be used in Weight-reducing and lipid-lowering product.The present composition can use this area routine side Prepared by method；Or preparation method is: stir after Rhizoma Imperatae extract and solvent are added container, add synergetic effect additive, rise Temperature, to 40-60 DEG C, stirs to being down to room temperature after the most molten and get final product；Or continue to filter, subpackage.This compositions is at relatively low addition (0.05%～3%) can play the effect of fat-eliminating slimming.

The synergetic effect additive used is alcohols or emulsifying agent, it is possible to plays the infiltration of the rush to effective plant fat reducing composition and makees With, improve the effect of formula, improve soft and smooth skinfeel.

The raw material that is easy to get of all Rhizoma Imperatae of solvent: root, leaf, flower, it is not necessary to deep processing, without toluene, ether, chloroform etc. Extractant extracts, it is to avoid the injury of chemical reagent, no solvent residue, and raw material is easy to get, low cost, directly with water extraction, takes Layer clear liquid.Human metabolism, heat-clearing and toxic substances removing can be promoted.Effectively get rid of internal harmful toxins, makes blood circulation smooth, resist Bacterium antiinflammatory, skin hypersensitivity pruritus can there be is certain effect.

Natural plant extracts of the present invention and synergetic effect additive fat reducing compositions, be not only effectively increased Rhizoma Imperatae extract Or effect of Cortex Mori extract lowering blood-fat and reducing weight, but also there is stronger antioxidation, can be used directly.The present invention is natural The vegetable composition suitability is wide, and usage amount is little, and alternative conventional wetting agent adds fat-reducing, vigorous and graceful emulsion, cosmetic cream to In.

Detailed description of the invention

The following examples contribute to those skilled in the art and the present invention are more fully understood, but limit never in any form The present invention.

Embodiment 1

Table 1. natural plant composition each formula inventory (weight %)

Compound method: in the appropriate size there-necked flask (such as 250mL) of band stirring and thermometer, according to each formula of table 1 Inventory, is initially charged plant extract and stirring solvent, adds synergetic effect additive, is warming up to 60 DEG C, stirs to complete molten rear fall To room temperature, stable fat reducing compositions i.e. can be obtained.

Embodiment 2

Reference standard QB/T2286-1997, observes the stability of 1# to 8# compositions in embodiment 1, the results are shown in Table 2, can See all conformance with standard requirements of the thermostability of lipid-lowering composition of the present invention, tolerance to cold and centrifugal test, there is good stability.

The stability of each formula of table 2.

Formula number	Thermostability	Tolerance to cold	Centrifugal test
				1#	Without separating	Without separating	Not stratified
2#	Without separating	Without separating	Not stratified
				3#	Without separating	Without separating	Not stratified
4#	Without separating	Without separating	Not stratified
				5#	Without separating	Without separating	Not stratified
6#	Without separating	Without separating	Not stratified
				7#	Without separating	Without separating	Not stratified
8#	Without separating	Without separating	Not stratified

Embodiment 3

The compositions with above-mentioned formula can be used alone, and also can make cream, emulsion use, as made cream, and can Join containing Dormant oils, Prunus dulcis (PRUNUS AMYGDALUS DULCIS) oil, the emulsion of glycosyl trehalose substrate or cream In.

Passing judgment on effect of body building and weight reducing class cosmetics, main detection experimenter's cosmetics use the improvement of position subcutaneous fat Situation, simultaneously using body weight, body fat rate two indices as auxiliary characteristics.

(1) according to " cosmetics health specification (2007 editions) " choose 18-60 year study subject.Nearly one week of experimenter is not Use antihistaminic or do not use immunosuppressant person in nearly one month；In nearly two months, recipient site does not applies any anti-inflammatory agent Thing or other affect the medicine person of using effect.

(2) both effectiveness and safety examination method

Experimenter: healthy, Simple Obesity 50 example, uses the time must not be made into cream less than 1 month in compositions ratio Frost uses.

Using method: 1, after the Water-heating shower by applicable temperature, somewhat water temperature is heightened 2-4 DEG C (according to self to heat Adaptedness regulate water temperature), rinse abdominal part 3-5 minute, dry skin；

2, take appropriate this product (extruding 5-7 drips) and be applied in abdominal part, with navel up and down as line, point left abdominal part and right abdominal part, Smearing respectively, it is ensured that whole abdominal part product slates is uniform, amount can increase less in right amount；

3, at abdominal part with hands counterclockwise rubbing or rub from top to bottom, the time of rubbing is 20-30 minute；(suggestion is coated with Preservative film is superscribed at abdominal part, about 40-50 minute time after smearing massage), after using, have burning sensation, according to self Situation, can not wrap up or open in advance.

50 people divide three groups, wherein fat reducing plant extract addition 3%, and in tester 20 people, wherein nonresponder 3, have Effect person 17.In 17, waistline reduces 6cm person, 2 people；3cm person, 4 people；2cm person, 9 people；1cm person, 2 people.There are two constipation Person, can be with relieving constipation after erasing cream；Having two experimenters, after erasing cream, waist edema phenomenon has been alleviated, and skin elasticity increases By force.

Fat reducing plant extract addition 0.05%, in tester 20 people, wherein nonresponder 9, responder 11.11 In Ming, waistline reduces 4cm person, 1 people；3cm person, 1 people；2cm person, 6；1cm person, 3.

Fat reducing plant extract addition 1%, in tester 10 people, wherein nonresponder 3, responder 7.In 7, Waistline reduces 4cm person, 1 people；3cm person, 2 people；2cm person, 2；1cm person, 2.

Conclusion: this fat reducing cream has certain effect to Weight-reducing and lipid-lowering, when addition is 3%, effective percentage is 85%；When adding Dosage is 1%, and effective percentage is 70%；When addition is only 0.05%, effective percentage also can reach 55%.And over the course for the treatment of There is defecating feces excretion, part population skin elasticity can be made to have alleviated, do not find untoward reaction, and after using 1 month, All find no rebound phenomena.

Claims

1. the fat reducing compositions of a Plant Extracts and synergetic effect additive contains:

A) plant extract；

B) synergetic effect additive；

C) solvent；

A in described compositions) plant extract includes one or both the mixing in Rhizoma Imperatae extract, Cortex Mori extract Thing.

Fat reducing compositions the most according to claim 1, it is characterised in that B in described compositions) synergetic effect additive includes sweet Dew alcohol, 1,2-butanediol, 1,2-ethohexadiol, phenethanol, 1,2-pentanediol, Sensiva SC50, glycerol citrate, poly-diformazan A kind of or the mixture of at least two kinds in radical siloxane, glycerol monolaurate.

Fat reducing compositions the most according to claim 1, it is characterised in that C in described compositions) solvent includes water, Herba Imperatae A kind of or the mixture of at least two in blade of grass aqueous extract, Herba Imperatae showy flowers of herbaceous plants aqueous extract, Rhizoma Imperatae aqueous extract.

Fat reducing compositions the most according to claim 1, it is characterised in that wherein, A in described compositions) plant extract Weight percentage be 1.0～30%, preferably 5～25%, more most preferably 10～20%.

5. according to the arbitrary described fat reducing compositions of claim 1 or 2, it is characterised in that B in described compositions) Synergistic The weight percentage of agent is 0.5～30%, preferably 1.0～20%.

6. according to the arbitrary described fat reducing compositions of claim 1 or 3, it is characterised in that C in described compositions) weight of solvent Amount percentage composition is 5～90%, preferably 15～70%, more preferably 20～60%.

Fat reducing compositions the most according to claim 3, it is characterised in that

Described Herba Imperatae blade of grass aqueous extract is to make to be soaked in water the solution of Rhizoma Imperatae leaf gained, and preparation method: based on 100% claims Take the Herba Imperatae blade of grass of 10%-50%, be torn into little bar or clay into power, add in 50%-90% water, soak 1-24 under room temperature little Time, then 40-100 DEG C of heating in water bath about 15 minutes, filter, take supernatant and be described Herba Imperatae blade of grass aqueous extract；

Described Herba Imperatae showy flowers of herbaceous plants aqueous extract is to make to be soaked in water the solution of Rhizoma Imperatae flower aqueous extract gained, preparation method: press 100% meter, weighs the Herba Imperatae showy flowers of herbaceous plants of 10%-50%, adds in 50%-90% water, soaks 1-24 hour, then exist under room temperature 40-100 DEG C of heating in water bath about 15 minutes, filters, takes supernatant and be described Herba Imperatae showy flowers of herbaceous plants aqueous extract；

Described Rhizoma Imperatae aqueous extract is the solution of the Rhizoma Imperatae gained making to be soaked in water fresh, preparation method: by 100% Meter, weighs the Rhizoma Imperatae of 10%-50%, is cut into small pieces or clays into power, and adds in 50%-90% water, soaks 1-under room temperature 24 hours, then 40-100 DEG C of heating in water bath about 15 minutes, filter, take supernatant and be described Rhizoma Imperatae water extraction Liquid.

8. be used for including this area cream according to the arbitrary described fat reducing compositions of claim 1-7, all products of emulsion subtract Fertile, blood fat reducing purposes.