CN106213034A - The vitamin premix of a kind of tilapia health improving tool metabolism syndrome and application - Google Patents
The vitamin premix of a kind of tilapia health improving tool metabolism syndrome and application Download PDFInfo
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- CN106213034A CN106213034A CN201610578014.0A CN201610578014A CN106213034A CN 106213034 A CN106213034 A CN 106213034A CN 201610578014 A CN201610578014 A CN 201610578014A CN 106213034 A CN106213034 A CN 106213034A
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- vitamin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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Abstract
The invention provides vitamin premix and the application of a kind of tilapia health improving tool metabolism syndrome.Described premix material includes vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, pantothenic acid, nicotinic acid, folic acid, inositol, biotin, vitamin C and adjuvant make.Feedstuff of the present invention is common, and with low cost, manufacture method is simple and reliable；The rational proportioning of various raw materials, can improve growth and the health level possessing metabolism syndrome tilapia, improve the premunition possessing metabolism syndrome tilapia.
Description
Technical field
The present invention relates to a kind of feed additive, particularly relate to a kind of tilapia health improving tool metabolism syndrome
Vitamin premix and application.
Background technology
The development of modern aquaculture be unable to do without the contribution of aquatic feeds, but in actual production, nearly all can send out
The Fish of existing various feedstuffs of ingesting the most likely occur that coefficient of condition is higher, intestinal expand thinning, visceral fat accumulation too much, blood
Analysis of Biochemical finds that Hyperlipemia, transaminase activity raise, and liver tissue slices finds swelling of liver cell, fat vacuole
The symptom of serious metabolism syndrome.This symptom be commonly due to feedstuff constitute unreasonable, throw something and feed excessive, poisonous
The factors such as the murder by poisoning of harmful substance.And have the fish of this symptom, resisting impact such as the water temperature acute variation, water quality ripple of poor environment
Move, when drawing in the net, easily caught by harmful microbe invasion and attack；Simultaneously, it is also possible to show the intolerance of transport, draw
The stress such as net overresponse, even there will be large quantities of death.For this problem, current solution is mainly passed through
Change feed formula, reduce feeding volume, utilize the modes such as Chinese herbal medicine conditioning to carry out, and lack fish nutrition after this problem occurs
Concern in terms of material aspect change.
Vitamin is to maintain a class nutrient substance necessary to fish bulk-growth and health.This kind of material is in vivo neither structure
Become the raw material of bodily tissue, be not the source of energy, but a class Auto-regulator, its important function in substance metabolism.As
Vitamin A has the dead effect with heat generation of active program sexual cell, is important fatty tissue growth regulator.Dimension
Raw element B1、B2、B6、B12, pantothenic acid, nicotiamide and biotin in sugar, protein, fat and energy metabolism, play important work
With.Wherein, vitamin B1Form the coenzyme of multiple branched-chain keto acids dehydrogenase in vivo, be oxidative deamination process in tricarboxylic acid cycle
Required composition；Vitamin B2It is the required ingredient of respiratory chain flavo-enzyme, biological oxidation transmits hydrogen；Nicotiamide is at body
Interior synthesis DPNH, and provide proton for oxidative phosphorylation process；Pantothenic acid is the ingredient of coenzyme A, is fatty acid oxygen
Change required material；Biotin is as the coenzyme of decarboxylase, involved in sugar heteroplasia and fatty acid oxidation.Vitamin C promotes fat
Fat is converted into energy, participates in fat and energy metabolism.Vitamin D is by the internal calcium metabolism of regulation and suppresses parathyroid hormone,
Cell Ca2+ influx, suppression obesity is avoided to occur.Vitamin E is important antioxidants, protects low density lipoprotein, LDL (low
Density lipoprotein, LDL) not oxidized.
But, this kind of material can not synthesize or synthetic quantity is not enough due to internal, so while requirement is little, but must be through
Often by food supply.But, along with the change of Fish physiological situation, the absorption of this type of material or metabolism can occur exception.People
In class medical science, as under fat state, there is various nutrients and lack in fat or overweight patient.Multivitamin, mineral exist
Fat generation, development play very important effect.Vitamin and mineral deficiency may result in the generation of obesity-related disease.
Auxiliary as weight intervention is treated, and supplements multivitamin and mineral contributes to controlling body weight, reducing body fat and whole body oxygen
Change stress, reduce obesity-related disease occur.But in Fish, carry out the most completely about research in this respect.
Tilapia is a kind of global important economic freshwater Fish, is excellent to world-wide deployment of FAO (Food and Agriculture Organization of the United Nation)
Good cultured fishes, become international one of main cultivation object.Over nearly 5 years, China mainland tilapia cultured output is about
1500000 tons, in freshwater aquiculture yield, occupy the 6th.It has the advantages such as feeding habits are miscellaneous, growth is fast, lower oxygen concentration resistance, premunition are strong.But
In breeding process, also will often find that fish body stomach fat is accumulated in a large number, the metabolism syndrome symptoms such as liver is loose.Existing grind
Study carefully that report is many to be solved in terms of Chinese medicine, Western medicine and pharmacology, and it needs the pass of change of vitamin under state to itself
Note less.Meanwhile, in the mixed feed of tilapia, conventional vitamin premix mostly is with under fish body healthiness condition, presses
Value according to the nutritional need meeting maximum growth rate is prepared.It was also found that Fish are occurring metabolism to combine in reality cultivates
During simulator sickness, a small amount of mixed feed manufacturer is had to have reached to improve by the way of increasing the addition of vitamin premix
The effect of part fish body health status, this effectively illustrates that vitamin is to tool metabolism syndrome under this kind of unsound state
The importance of symptom healthy fish, but this interpolation has randomness and uncertainty, such as whether mean all vitamins
Component will increase, and the most only needs the problem such as content increasing some vitamin the most on the knees of the gods.
Summary of the invention
For problem above, it is an object of the invention to when the symptom of Rofe fishing gear metabolism syndrome, it is provided that a kind of permissible
Improve the vitamin premix of its health status.
It is a further object to provide a kind of vitamin premix to improve tilapia metabolism syndrome in preparation and raise
Application in material.
To achieve these goals, the present invention uses techniques below measure:
The vitamin premix that a kind of tilapia improving tool metabolism syndrome is healthy, every 100 kilograms of premix material effective
Composition includes:
Remaining is one or more in the conventional adjuvant of this area, such as wheat bran, defatted rice bran, zeolite powder.
Above-mentioned various vitamin addition refers both to the pure material quality of 100%, and in actual fabrication process, material used has
Certain purity, is convertible into actual contents usage amount by actually active content.
Above-described vitamin premix, preferably:
Above-described vitamin premix, preferably:
Above-described vitamin premix, preferably:
Above-described vitamin premix, preferably:
A kind of vitamin premix improves the application in tilapia metabolism syndrome feedstuff in preparation, it is preferred that described
Vitamin premix in feedstuff accounts for the 0.3～1% of feedstuff gross mass.
In schemes described above, it is preferred that the described vitamin premix in feedstuff accounts for feedstuff gross mass
0.5%.
In schemes described above, it is preferred that described feed formula includes:
In schemes described above, preferably:
Every gram of compound mineral salts contains: Ca (H2PO4)2·H2O,135.8mg；Ca(CH3CHOHCOO)2·5H2O,
327mg；MgSO4·7H2O,137mg；NaH2PO4,87.2mg；AlCl3·6H2O,0.15mg；KCl,75mg；CuCl2·.2H2O,
0.1mg；MnSO4·H2O, 0.80mg；CoCl2·6H2O,1mg；ZnSO4·7H2O, 3mg；Remaining is cellulose.
Compared with prior art, there is advantages that
(1) improvement possesses growth and the health level of metabolism syndrome tilapia.With commercially available tilapia vitamin premix
Material carried out contrast experiment, result shows to significantly improve the rate of body weight gain of tilapia, reduce coefficient of condition, serum total cholesterol,
Content of triglyceride.
(2) improve and possess the immunity of metabolism syndrome tilapia.Carry out with commercially available tilapia vitamin premix
Contrast experiment, challenge test shows to significantly improve survival rate.
Detailed description of the invention
The present invention is explained further below in conjunction with embodiment, but the present invention is not done any type of limit by embodiment
Fixed.Technical scheme of the present invention, such as not special standby explanation, is the ordinary skill in the art；Described reagent or material, as not special
Standby explanation, derives from commercial channel.
Embodiment 1:
A kind of vitamin premix of the tilapia health improving tool metabolism syndrome, every 100 kilograms of vitamin premixs
Including:
In the usual way by above-mentioned each component mix homogeneously.
Vitamin A derives from the feed grade retinyl acetate microgranule that purity is 500,000 IU/g；Vitamin D derives from pure
Degree is 500,000 IU/g feed grade vitamin D3Microgranule；Vitamin C is the coated vitamin C of 35%；Pantothenic acid is the calcium pantothenate of 92%,
The purity of other actual raw material of each vitamin is:
By the purity of above-mentioned each vitamin raw materials, the consumption of actual vitamin raw materials can be calculated:
Embodiment 2:
A kind of vitamin premix improves the application in tilapia metabolism syndrome feedstuff in preparation:
Vitamin premix embodiment 1 prepared adds to feedstuff, makes (the heavy property examination of tilapia sinking property test feed
Test feed formula and be shown in Table 1), meanwhile, utilize certain vitamin premix used by tilapia feed enterprise commercially available to make matched group and raise
Material, culture experiment is carried out in the cultivating workshop of Aquatic product institute Wuhan, the Changjiang river.The gift tilapia of original body mass 20g is through too high sugar
(45%) high fat (12%) feedstuff feeding is after 40 days, sets up Metabolic Syndrome.Then test fish is randomly divided into 3 groups, often
Group 3 repetition, often repeats 30 tails, and one group is continued to feed high glucose and high fat feedstuff, one group of testing material of throwing something and feeding, one group of control feed of throwing something and feeding, supports
Grow 4 weeks.After experiment terminates, the tilapia opisthosoma that the present invention is thrown something and fed is heavily for 149g, relatively matched group raising 13.7%, height of relatively throwing something and feeding
The test group of sugar high lipid food improves 33.0%, reduces serum total cholesterol and sweet compared with matched group and high glucose and high fat group
Oil three ester contents.Another every barrel of random choose 10 tail fish, after streptococcus agalactiae counteracting toxic substances 12 days, the survival rate of experimental group relatively matched group
It is respectively increased 19.9% and 100% with high glucose and high fat group.
Table 1
| Material name | Mass fraction (%) |
| Fish flour | 2.00 |
| Bean cake | 20.00 |
| Rapeseed cake | 18.00 |
| Cottonseed meal | 10.00 |
| Zein powder | 8.00 |
| Soybean oil | 3.50 |
| Wheat-middlings | 25.00 |
| Testa oryzae | 8.00 |
| Vitamin premix | 0.50 |
| Choline chloride | 0.50 |
| Compound mineral salts | 2.00 |
| Dalcium biphosphate | 1.50 |
| Bentonite | 1.00 |
Note: in table, every gram of compound mineral salts contains: Ca (H2PO4)2·H2O,135.8mg；Ca(CH3CHOHCOO)2·
5H2O,327mg；MgSO4·7H2O,137mg；NaH2PO4,87.2mg；AlCl3·6H2O,0.15mg；KCl,75mg；
CuCl2·.2H2O,0.1mg；MnSO4·H2O, 0.80mg；CoCl2·6H2O,1mg；ZnSO4·7H2O, 3mg；Remaining is fiber
Element.
Embodiment 3:
A kind of vitamin premix of the tilapia health improving tool metabolism syndrome, every 100 kilograms of vitamin premixs
Including:
The calculation of each component of above-described vitamin premix and compound method are with embodiment 1.
Embodiment 4:
A kind of vitamin premix improves the application in tilapia metabolism syndrome feedstuff in preparation:
In July, 2015 finds in some pond, and the tilapia abdominal part of cultivation expands, and dissects and finds accumulation of abdominal fat mistake
Greatly, liver enlargement.Therefore, vitamin premix embodiment 3 prepared adds to feedstuff, makes the test of sinking property of tilapia and raises
Material (heavy property test feed formula is shown in Table 2), meanwhile, utilizes certain vitamin premix used by tilapia feed enterprise commercially available to make
Matched group feedstuff.The pond selecting 2 conditions of similarities carries out test 40 days of throwing something and feeding.It was found that relatively matched group, the present invention is thrown
The tilapia opisthosoma fed is heavily 468g, and relatively matched group improves 4.7%, meanwhile, reduces the crude fat content of liver, the total gallbladder of serum
Sterin and content of triglyceride.
Table 2
Note: contain in every gram of compound mineral salts in table: Ca (H2PO4)2·H2O,135.8mg；Ca(CH3CHOHCOO)2·
5H2O,327mg；MgSO4·7H2O,137mg；NaH2PO4,87.2mg；AlCl3·6H2O,0.15mg；KCl,75mg；
CuCl2·.2H2O,0.1mg；MnSO4·H2O, 0.80mg；CoCl2·6H2O,1mg；ZnSO4·7H2O, 3mg；Remaining is fiber
Element.
Claims (10)
1. improve the vitamin premix that the tilapia of tool metabolism syndrome is healthy, effective one-tenth of every 100 kilograms of premix material
Divide and include:
Vitamin A 2500～30,000,000 IU vitamin D 200～6,000,000 IU
Vitamin E 2000～2500 g vitamin K 100～150 g
Vitamin B1100～300 g vitamin Bs290～200g
Nicotinic acid 2000～2800 g pantothenic acid 250～350 g
Vitamin B6100～280 g folic acid 20～30 g
Biotin 5～15 g inositol 20000～30000 g
Vitamin B1210～20g vitamin C 10000～20000 g.
Vitamin premix the most according to claim 1, it is characterised in that:
Vitamin A 2500～28,000,000 IU vitamin D 200～4,000,000 IU
Vitamin E 2200～2500 g vitamin K 120～150 g
Vitamin B1100～200 g vitamin Bs2110～220g
Nicotinic acid 2000～2800 g pantothenic acid 250～350 g
Vitamin B6160～280 g folic acid 20～28 g
Biotin 5～10 g inositol 22000～26000 g
Vitamin B1210～15g vitamin C 12000～18000 g.
Vitamin premix the most according to claim 1, it is characterised in that:
Vitamin A 2500～26,000,000 IU vitamin D 220～2,800,000 IU
Vitamin E 2300～2400 g vitamin K 140～150 g
Vitamin B1150～200 g vitamin Bs2160～200g
Nicotinic acid 2500～2800 g pantothenic acid 300～350 g
Vitamin B6250～280 g folic acid 25～28 g
Biotin 6～9 g inositol 25000～26000 g
Vitamin B1210～12g vitamin C 16000～17000 g.
Vitamin premix the most according to claim 1, it is characterised in that:
Vitamin A 25,500,000 IU vitamin D 2,200,000 IU
Vitamin E 2400 g vitamin K 150 g
Vitamin B1180 g vitamin Bs2 160g
Nicotinic acid 2800 g pantothenic acid 325 g
Vitamin B6275 g folic acid 26 g
Biotin 9 g inositol 26000 g
Vitamin B1212g vitamin C 16000 g.
Vitamin premix the most according to claim 1, it is characterised in that:
Vitamin A 26,000,000 IU vitamin D 2,500,000 IU
Vitamin E 2380 g vitamin K 145 g
Vitamin B1150 g vitamin Bs2 160g
Nicotinic acid 2600 g pantothenic acid 320 g
Vitamin B6270 g folic acid 25 g
Biotin 6 g inositol 25500 g
Vitamin B1210g vitamin C 16000 g.
6. the vitamin premix described in claim 1 improves the application in tilapia metabolism syndrome feedstuff in preparation.
Application the most according to claim 6, the described vitamin premix in feedstuff accounts for the 0.3 ~ 1% of feedstuff gross mass.
Application the most according to claim 7, the described vitamin premix in feedstuff accounts for the 0.5% of feedstuff gross mass.
Application the most according to claim 8, described feed formula includes:
Raw materials quality mark, %
Fish flour 2.00
Bean cake 20.00
Rapeseed cake 18.00
Cottonseed meal 10.00
Zein powder 8.00
Soybean oil 3.50
Wheat-middlings 25.00
Testa oryzae 8.00
Vitamin premix 0.50
Choline chloride 0.50
Compound mineral salts 2.00
Dalcium biphosphate 1.50
Bentonite 1.00.
Application the most according to claim 9, contains in every gram of described compound mineral salts: Ca (H2PO4)2•H2O, 135.8
mg; Ca(CH3CHOHCOO)2•5H2O, 327 mg；MgSO4•7H2O, 137 mg；NaH2PO4, 87.2mg；AlCl3•6H2O,
0.15 mg；KCl, 75 mg；CuCl2•.2H2O, 0.1 mg；MnSO4• H2O, 0.80 mg；CoCl2•6H2O, 1 mg；
ZnSO4•7H2O, 3 mg；Remaining is cellulose.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610578014.0A CN106213034B (en) | 2016-07-21 | 2016-07-21 | It is a kind of improve tool metabolic syndrome Tilapia mossambica health vitamin premix and application |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610578014.0A CN106213034B (en) | 2016-07-21 | 2016-07-21 | It is a kind of improve tool metabolic syndrome Tilapia mossambica health vitamin premix and application |
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| CN106213034A true CN106213034A (en) | 2016-12-14 |
| CN106213034B CN106213034B (en) | 2019-11-01 |
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| CN201610578014.0A Active CN106213034B (en) | 2016-07-21 | 2016-07-21 | It is a kind of improve tool metabolic syndrome Tilapia mossambica health vitamin premix and application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106798197A (en) * | 2017-01-03 | 2017-06-06 | 福建粤海饲料有限公司 | A kind of compounding sea algae feedstuff additive for sea water fish |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101869227A (en) * | 2010-06-13 | 2010-10-27 | 湛江恒兴特种饲料有限公司 | Compound feed of tilapia |
| CN102265983A (en) * | 2011-08-02 | 2011-12-07 | 广东省农业科学院畜牧研究所 | Tilapia feed with high sugar content and low protein content |
| CN103783319A (en) * | 2014-01-21 | 2014-05-14 | 中国水产科学研究院长江水产研究所 | Vitamin premix for tilapia mossambica in medium-term growth and preparation method thereof |
| CN105558436A (en) * | 2016-02-04 | 2016-05-11 | 湛江恒兴珊瑚饲料有限公司 | Expanded feed for resisting fatty liver of tilapia and preparation method |
-
2016
- 2016-07-21 CN CN201610578014.0A patent/CN106213034B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101869227A (en) * | 2010-06-13 | 2010-10-27 | 湛江恒兴特种饲料有限公司 | Compound feed of tilapia |
| CN102265983A (en) * | 2011-08-02 | 2011-12-07 | 广东省农业科学院畜牧研究所 | Tilapia feed with high sugar content and low protein content |
| CN103783319A (en) * | 2014-01-21 | 2014-05-14 | 中国水产科学研究院长江水产研究所 | Vitamin premix for tilapia mossambica in medium-term growth and preparation method thereof |
| CN105558436A (en) * | 2016-02-04 | 2016-05-11 | 湛江恒兴珊瑚饲料有限公司 | Expanded feed for resisting fatty liver of tilapia and preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106798197A (en) * | 2017-01-03 | 2017-06-06 | 福建粤海饲料有限公司 | A kind of compounding sea algae feedstuff additive for sea water fish |
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| Publication number | Publication date |
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| CN106213034B (en) | 2019-11-01 |
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Effective date of registration: 20230307 Address after: No. 055, Longtianyi Industrial Park, 107 National Road, Zhengdian Street, Jiangxia District, Wuhan, Hubei Province, 430000 Patentee after: Wuhan Qixinsheng Biotechnology Co.,Ltd. Patentee after: Wuhan Zhongshuikang Ecological Technology Co.,Ltd. Address before: 430223 No.8, wudayuan 1st Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee before: YANGTZE RIVER FISHERIES Research Institute CHINESE ACADEMY OF FISHERY SCIENCES |
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