CN106178094A - A kind of liquid adhesive bandage and preparation method thereof - Google Patents
A kind of liquid adhesive bandage and preparation method thereof Download PDFInfo
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- CN106178094A CN106178094A CN201610578173.0A CN201610578173A CN106178094A CN 106178094 A CN106178094 A CN 106178094A CN 201610578173 A CN201610578173 A CN 201610578173A CN 106178094 A CN106178094 A CN 106178094A
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- adhesive bandage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The present invention provides a kind of liquid adhesive bandage and preparation method thereof; belong to field of medical products; liquid adhesive bandage is by by nitrocellulose; Oleum Ricini; castor oil hydrogenated; dioctyl phthalate; benzyl alcohol, ethyl acetate, butyl acetate; regulate pH value after isopropanol mixing to prepare to 6～8; after the liquid adhesive bandage that the present invention prepares applies to wound surface, can in 1～2min fast filming, and effectively completely cut off moisture, dust and dirt and bacterial invasion; protect the wound from infecting and healing acceleration, and soft, smooth, the good difficult drop-off of sticking nature.
Description
Technical field
The present invention relates to field of medical products, and particularly to a kind of liquid adhesive bandage and preparation method thereof.
Background technology
The adhesive bandage that stub is sold in the market, generally by an elongated adhesive plaster, centre is accompanied by a dipped medicine of fritter
Sliver constitute.Its adhesive plaster poor air permeability used, the body local normocrinic steam of institute and perspiration can not penetrate this layer of glue
Cloth, then produces action of soaking to local skin, is embodied in local skin and the situation of wrinkle bar, and easy infection occurs.
At present, have some liquid adhesive bandage products on the market, but the film-formation result of these liquid adhesive bandage products be poor,
Easily from skin exfoliation and have more abnormal flavour, do not have good anti-infectious effect.
Summary of the invention
It is an object of the invention to provide a kind of liquid adhesive bandage, this liquid adhesive bandage on skin can fast filming,
Softness, smooth, difficult drop-off sticking nature is good, breathes freely and effectively completely cuts off moisture, dust and dirt and bacterial invasion, attractive in appearance, protects wound
From infect and can accelerating wound healing.
The present invention solves it and technical problem is that and realize by the following technical solutions:
A kind of liquid adhesive bandage, percentage, including nitrocellulose 5%～10%, Oleum Ricini 0.1%～
1%, castor oil hydrogenated 0.5%～1.5%, dioctyl phthalate 1%～2%, benzyl alcohol 17%～19%, ethyl acetate
14%～15%, butyl acetate 50%～55%, isopropanol 3%～5%.
Another object of the present invention is to provide the preparation method of a kind of liquid adhesive bandage, can with prepared aforesaid liquid wound
Patch.
The present invention solves it and technical problem is that and realize by the following technical solutions.
The preparation method of aforesaid liquid adhesive bandage, by nitrocellulose, Oleum Ricini, castor oil hydrogenated, phthalic acid two
Monooctyl ester, benzyl alcohol, ethyl acetate, butyl acetate, regulate pH value after isopropanol mixing and prepare liquid adhesive bandage to 6～8.
Liquid adhesive bandage that present pre-ferred embodiments provides and preparation method thereof provides the benefit that: the embodiment of the present invention
The liquid adhesive bandage raw material provided is plant extract and medicinal rank raw material, and materials safety is reliable.And Oleum Ricini and hydrogenation
Oleum Ricini etc. are plant extract quintessence oil, have the most antibacterial and antibacterial action, are also natural preservative.It is being applied on skin
Behind face, liquid adhesive bandage can quickly form softness, smooth, and the film of difficult drop-off effectively completely cuts off moisture, dust and dirt and antibacterial,
Protect the wound from infecting and accelerating wound healing.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below will be in the embodiment of the present invention
Technical scheme be clearly and completely described.In embodiment, unreceipted actual conditions person, builds according to normal condition or manufacturer
The condition of view is carried out.Agents useful for same or instrument unreceipted production firm person, being can be by the commercially available conventional product bought and obtain
Product.
Liquid adhesive bandage, percentage, including nitrocellulose 5%～10%, Oleum Ricini 0.1%～1%, hydrogen
Change Oleum Ricini 0.5%～1.5%, dioctyl phthalate 1%～2%, benzyl alcohol 17%～19%, ethyl acetate 14%～
15%, butyl acetate 50%～55%, isopropanol 3%～5%.Wherein, nitrocellulose has another name called nitrocotton, is cellulose and nitre
The product of Esterification reaction, it is white or slightly yellow flocculence.In the present invention, low nitrogen digestion cellucotton (NC) is preferably used,
Low nitrogen herein refers to that the nitrogen content of nitrocellulose cotton is less than 12.5%.
More preferably, the cotton mass percent in liquid adhesive bandage of nitrocellulose is 6%～9%.
Semen Ricini (Ricinus communis L.), Euphorbiaceae, Ricinus be annual or herbaceos perennial, the torrid zone or
Southern area often becomes perennial shrub or dungarunga.Oleum Ricini is the extract extracted from Semen Ricini, and it has detumescence and drawing out poison, only
Itch, expelling wind and activating blood circulation, pain relieving is calm and the effect such as dissipating blood stasis.It is used in liquid adhesive bandage, patient wound can be carried out disinfection, kill
Antibacterial, prevents infection.As preferably, in liquid adhesive bandage, the percetage by weight of Oleum Ricini be preferably 0.4%～
0.6%, can be such as 0.5%.By allocating the amount of suitable Oleum Ricini, can effectively kill pathogenic bacteria simultaneously will not be too much
Human normal cell is produced bigger damage.
Castor oil hydrogenated is prepared by Oleum Ricini hydrogenation, is mainly composed of 12-hydroxyl stearic acid triglyceride.Hydrogenation castor
Oleum Sesami can play the effects such as thickening, Hardening and slow release, therefore is used as thickening agent, Hardening agent and slow releasing agent, is used for preparing semisolid
Preparation and solid preparation, such as ointment, suppository, pill, tablet etc..In the present invention, castor oil hydrogenated adds liquid adhesive bandage
After, when application to wound, liquid adhesive bandage fast filming can be made, and the protecting film caking property of molding is good, is difficult to from wound
Place comes off.
More excellent, castor oil hydrogenated percetage by weight in liquid adhesive bandage is 0.8%～1.2%, holds above-mentioned, properly
The proportioning of castor oil hydrogenated, can make liquid adhesive bandage film forming faster after application, and more conducively liquid after film forming
Adhesive bandage is close to wound, it is to avoid it comes off.
Dioctyl phthalate (Dioctyl Phthalate), is called for short dioctyl ester (DOP), is a kind of organosilane ester
Compound, can be used as plasticizer.In present pre-ferred embodiments, dioctyl phthalate can be with the one-tenth of accelerating liquid adhesive bandage
Film speed.Meanwhile, the film of molding is attractive in appearance, soft, smooth.As preferably, dioctyl phthalate is in liquid adhesive bandage
Percetage by weight is 1.5%～2%.
Benzyl alcohol is colourless liquid, and benzyl alcohol has slight anesthetic action, after being applied to the wound of skin, can rise
To analgesic activity, especially for the wound such as knife injury, scuffing, benzyl alcohol can play slight local anesthesia effect, prevents patient
Because of pain or scratchy wound is scratched, cause secondary damage.As preferably, benzyl alcohol weight hundred in liquid adhesive bandage
Mark is 17.5%～18.5%, for example, 18%.
Butyl acetate is a kind of excellent organic solvent, and in present pre-ferred embodiments, butyl acetate is as solvent, nitre
The material such as cellulose, Oleum Ricini all can well be dissolved in wherein, especially good to the dissolubility of nitrocellulose.By closing
Reason allotment butyl acetate content, it is ensured that nitrocellulose can be completely dissolved and can after application fast filming.As preferably, second
The percetage by weight of acid butyl ester is 52%～54%.
Ethyl acetate is a kind of excellent organic solvent equally, its can not only rapid solution nitrocellulose, and work as liquid
After body adhesive bandage is deposited, ethyl acetate and butyl acetate all can volatilize by rapid-curing cutback so that nitrocellulose separates out and fast rapid-result
Film solidifies, and docile is on the skin of wound.As preferably, in liquid adhesive bandage, the percetage by weight of ethyl acetate is
14.4%～14.6%.
Aforesaid liquid adhesive bandage is prepared, by nitrocellulose, Oleum Ricini, castor oil hydrogenated, phthalic acid
Dioctyl ester, benzyl alcohol, ethyl acetate, butyl acetate, after isopropanol mixing, regulation pH value is to 6～8, prepares this liquid adhesive bandage.
The liquid adhesive bandage pH value prepared through said method is consistent with the acid-base value of human body, and human body preferably uses.
Additionally, the moderate viscosity of the liquid adhesive bandage obtained through said method, when application, liquid adhesive bandage can be well
Docile is also unlikely to cause the most serious viscous glutinous sense to cause discomfort at skin surface simultaneously, as preferably, and aforesaid liquid adhesive bandage
Viscosity under the conditions of 25 DEG C should be not more than 25Pa s.
Additionally, the liquid adhesive bandage that said method prepares, owing to the major antibacterial composition in raw material all extracts from natural planting
Thing, will not produce sensitivity response by human body, also skin will not be produced irritant reaction, and it is anti-to the toxicity of human normal cell simultaneously
Should be no more than 2 grades.According to the difference of consumption, aforesaid liquid adhesive bandage can be prepared as 5g, 8g, 10g, 12g, 15g, 20g,
The specification that 25g etc. are different.
The liquid adhesive bandage provided the present invention below in conjunction with specific embodiment is described further.
Embodiment 1
Weigh nitrocellulose 0.5Kg, Oleum Ricini 0.06Kg, castor oil hydrogenated 0.05Kg, dioctyl phthalate
0.2Kg, benzyl alcohol 1.7Kg, ethyl acetate 1.5Kg, butyl acetate 5.5Kg, isopropanol 0.49Kg.Above-mentioned each composition is mixed
After, measuring pH value is 6.8 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.This liquid adhesive bandage is recorded under the conditions of 25 DEG C
Viscosity be 24.3Pa s.
Embodiment 2
Weigh nitrocellulose 0.55Kg, Oleum Ricini 0.055Kg, castor oil hydrogenated 0.06Kg, dioctyl phthalate
0.195Kg, benzyl alcohol 1.74Kg, ethyl acetate 1.49Kg, butyl acetate 5.4Kg, isopropanol 0.51Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.85 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24.7Pa s.
Embodiment 3
Weigh nitrocellulose 0.6Kg, Oleum Ricini 0.05Kg, castor oil hydrogenated 0.07Kg, dioctyl phthalate
0.19Kg, benzyl alcohol 1.78Kg, ethyl acetate 1.48Kg, butyl acetate 5.35Kg, isopropanol 0.48Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.95 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24Pa s.
Embodiment 4
Weigh nitrocellulose 0.65Kg, Oleum Ricini 0.045Kg, castor oil hydrogenated 0.08Kg, dioctyl phthalate
0.185Kg, benzyl alcohol 1.8Kg, ethyl acetate 1.47Kg, butyl acetate 5.3Kg, isopropanol 0.47Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.8 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24.1Pa s.
Embodiment 5
Weigh nitrocellulose 0.74Kg, Oleum Ricini 0.05Kg, castor oil hydrogenated 0.09Kg, dioctyl phthalate
0.18Kg, benzyl alcohol 1.82Kg, ethyl acetate 1.46Kg, butyl acetate 5.36Kg, isopropanol 0.3Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.72 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 23.8Pa s.
Embodiment 6
Weigh nitrocellulose 0.75Kg, Oleum Ricini 0.04Kg, castor oil hydrogenated 0.1Kg, dioctyl phthalate
0.17Kg, benzyl alcohol 1.84Kg, ethyl acetate 1.45Kg, butyl acetate 5.3Kg, isopropanol 0.35Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.77 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24.3Pa s.
Embodiment 7
Weigh nitrocellulose 0.8Kg, Oleum Ricini 0.035Kg, castor oil hydrogenated 0.11Kg, dioctyl phthalate
0.16Kg, benzyl alcohol 1.86Kg, ethyl acetate 1.44Kg, butyl acetate 5.25Kg, isopropanol 0.345Kg.By above-mentioned each composition
After mixing, measuring pH value is 6.69 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.This liquid wound is recorded under the conditions of 25 DEG C
The viscosity that can paste is 23.8Pa s.
Embodiment 8
Weigh nitrocellulose 0.85Kg, Oleum Ricini 0.03Kg, castor oil hydrogenated 0.12Kg, dioctyl phthalate
0.15Kg, benzyl alcohol 1.87Kg, ethyl acetate 1.43Kg, butyl acetate 5.2Kg, isopropanol 0.35Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.84 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24.5Pa s.
Embodiment 9
Weigh nitrocellulose 0.9Kg, Oleum Ricini 0.02Kg, castor oil hydrogenated 0.13Kg, dioctyl phthalate
0.12Kg, benzyl alcohol 1.88Kg, ethyl acetate 1.43Kg, butyl acetate 5.2Kg, isopropanol 0.35Kg.Above-mentioned each composition is mixed
After conjunction, measuring pH value is 6.77 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.Recording this liquid wound under the conditions of 25 DEG C can
The viscosity of patch is 24.0Pa s.
Embodiment 10
Weigh nitrocellulose 1Kg, Oleum Ricini 0.01Kg, castor oil hydrogenated 0.15Kg, dioctyl phthalate
0.1Kg, benzyl alcohol 1.9Kg, ethyl acetate 1.4Kg, butyl acetate 5Kg, isopropanol 0.44Kg.After above-mentioned each composition is mixed,
Measuring pH value is 6.58 to meet acid-base value requirement, i.e. prepares liquid adhesive bandage.This liquid adhesive bandage is recorded under the conditions of 25 DEG C
Viscosity is 23.5Pa s.
The liquid adhesive bandage obtaining above-described embodiment carries out film formation time test, and with other commercially available liquid adhesive bandages
Measuring the film formation time of liquid adhesive bandage as a control group, method of testing is: choose experimenter 10 people of 15～45 years old age bracket,
Respectively at each experimenter arm skin application above-described embodiment 1～10 obtain liquid adhesive bandage and the liquid of matched group
Adhesive bandage, records the film formation time of each application and adds up the average film formation time of each embodiment and matched group.During film forming
Between drop to skin for liquid adhesive bandage and rise to liquid adhesive bandage and formed protecting film.Experimental data is shown in Table 1:
Table 1 liquid adhesive bandage film formation time tables of data
From upper table data, after the liquid adhesive bandage obtained through above-described embodiment is in application to human body skin, during film forming
Between all in 1～2min, relatively commercially available prod is significantly shortened, meanwhile, compared with existing liquid adhesive bandage, all do not have from apply
The situation that use comes off.
Repetition above-described embodiment is to prepare abundant liquid adhesive bandage, simultaneously with commercial liquid adhesive bandage as matched group,
Choose 100 healthy mices, use cutter that the leg muscle of mice causes the scuffing of local, in scratching half an hour, wound is applied
The liquid adhesive bandage prepared with above-described embodiment, whether the wound of observation mice receives antibacterial infection conditions record.Obtained
Data are shown in Table 2
Table 2
From the data in table 2, it can be seen that the liquid adhesive bandage that the above embodiment of the present invention obtains is made for common knife injury, scratch etc.
The anti-infectious effect of the wound become is good, and the antibacterial of common easy infection wound is had preferable killing action, meanwhile, breathability
Good, skin will not be made to produce ugly fold.
The liquid adhesive bandage that above-described embodiment prepares may be used for agnail, incised wound, abrade, scratch, split, burn,
The protection of some minor cut or wounds such as scald, cold injury and promotion healing.After applying to wound surface, can in 1～2min fast filming,
And effectively completely cut off moisture, dust and dirt and bacterial invasion, protect the wound from infect and healing acceleration, and soft, smooth, sticking nature is good
Difficult drop-off.
Embodiments described above is a part of embodiment of the present invention rather than whole embodiments.The reality of the present invention
The detailed description executing example is not intended to limit the scope of claimed invention, but is merely representative of the selected enforcement of the present invention
Example.Based on the embodiment in the present invention, those of ordinary skill in the art are obtained under not making creative work premise
Every other embodiment, broadly falls into the scope of protection of the invention.
Claims (10)
1. a liquid adhesive bandage, it is characterised in that percentage, including nitrocellulose 5%～10%, Oleum Ricini
0.1%～1%, castor oil hydrogenated 0.5%～1.5%, dioctyl phthalate 1%～2%, benzyl alcohol 17%～19%,
Ethyl acetate 14%～15%, butyl acetate 50%～55%, isopropanol 3%～5%.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 6%～9%
Described nitrocellulose.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 0.4%～
The described Oleum Ricini of 0.6%.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 0.8%～
The described castor oil hydrogenated of 1.2%.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 1.5%～2%
Described dioctyl phthalate.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 17.5%～
The described benzyl alcohol of 18.5%.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 52%～54%
Described butyl acetate.
Liquid adhesive bandage the most according to claim 1, it is characterised in that percentage, including 14.4%～
The described ethyl acetate of 14.6%.
Liquid adhesive bandage the most according to claim 1, it is characterised in that described liquid adhesive bandage sticking under the conditions of 25 DEG C
Degree is not more than 25Pa s.
10. the preparation method of the liquid adhesive bandage as described in any one of claim 1～9, it is characterised in that by described nitre
Cellulose, described Oleum Ricini, described castor oil hydrogenated, described dioctyl phthalate, described benzyl alcohol, described acetic acid second
Ester, described butyl acetate, regulate pH value to 6～8 after the mixing of described isopropanol and prepare described liquid adhesive bandage.
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| CN106924803A (en) * | 2017-05-05 | 2017-07-07 | 江南大学 | A kind of high-performance medical use liquid adhesive bandage and preparation method thereof |
| CN107661537A (en) * | 2017-10-18 | 2018-02-06 | 张家港蓝智生物科技有限公司 | A kind of liquid Wound surface protection film containing biological glass ceramic and chitosan |
| CN109224122A (en) * | 2018-09-20 | 2019-01-18 | 天津科技大学 | A kind of antibacterial liquid adhesive bandage and preparation method thereof |
| CN109833511A (en) * | 2017-11-29 | 2019-06-04 | 江苏双盛医疗器械有限公司 | A kind of hemostasia and detumescence adhesive bandage |
| CN109833512A (en) * | 2017-11-29 | 2019-06-04 | 江苏尚铖医疗器械有限公司 | A kind of multi-functional adhesive bandage |
| CN110101900A (en) * | 2019-06-20 | 2019-08-09 | 江西高大生物医疗科技有限公司 | A kind of film forming agent of the insulation blocking surface of a wound |
| CN110859989A (en) * | 2019-10-25 | 2020-03-06 | 天津冠勤医药科技有限公司 | Liquid band-aid and preparation method thereof |
| CN114732942A (en) * | 2022-04-12 | 2022-07-12 | 兰州大学 | Chlorine dioxide slow-release liquid band-aid and preparation method thereof |
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| CN106924803A (en) * | 2017-05-05 | 2017-07-07 | 江南大学 | A kind of high-performance medical use liquid adhesive bandage and preparation method thereof |
| CN107661537A (en) * | 2017-10-18 | 2018-02-06 | 张家港蓝智生物科技有限公司 | A kind of liquid Wound surface protection film containing biological glass ceramic and chitosan |
| CN109833511A (en) * | 2017-11-29 | 2019-06-04 | 江苏双盛医疗器械有限公司 | A kind of hemostasia and detumescence adhesive bandage |
| CN109833512A (en) * | 2017-11-29 | 2019-06-04 | 江苏尚铖医疗器械有限公司 | A kind of multi-functional adhesive bandage |
| CN109224122A (en) * | 2018-09-20 | 2019-01-18 | 天津科技大学 | A kind of antibacterial liquid adhesive bandage and preparation method thereof |
| CN110101900A (en) * | 2019-06-20 | 2019-08-09 | 江西高大生物医疗科技有限公司 | A kind of film forming agent of the insulation blocking surface of a wound |
| CN110859989A (en) * | 2019-10-25 | 2020-03-06 | 天津冠勤医药科技有限公司 | Liquid band-aid and preparation method thereof |
| CN114732942A (en) * | 2022-04-12 | 2022-07-12 | 兰州大学 | Chlorine dioxide slow-release liquid band-aid and preparation method thereof |
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Application publication date: 20161207 |