CN106177963A - 用于治疗癌症或癌前病症的交错方法 - Google Patents
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Molecular Biology (AREA)
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- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| CN102781316B (zh) | 2010-03-01 | 2016-07-06 | 陶制药有限责任公司 | 癌症诊断和成像 |
| EP2755674A4 (en) * | 2011-09-12 | 2015-04-08 | Tau Therapeutics Llc | ANTAGONISTS OF PRODUCTS OF THE HS-459642-UNIGEN CLUSTER TO AVOID PROLIFERATION, DEVELOPMENT, OR DIFFERENTIATION OF STEM CELLS WITH CANCER STEM CELLS |
| US11642353B2 (en) | 2014-02-06 | 2023-05-09 | The Procter & Gamble Company | Hair care composition comprising antidandruff agent and polyquaternium-6 |
| US11058624B2 (en) | 2014-02-06 | 2021-07-13 | The Procter And Gamble Company | Hair care composition comprising cationic polymers and anionic particulates |
| EP3364993B1 (en) | 2015-10-22 | 2022-11-09 | Cavion, Inc. | Methods for treating angelman syndrome |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| CN110545806A (zh) | 2017-02-15 | 2019-12-06 | 卡维昂公司 | 钙通道抑制剂 |
| EP3615521A4 (en) | 2017-04-26 | 2021-02-17 | Cavion, Inc. | METHODS FOR IMPROVING MEMORY AND COGNITION AND TREATING MEMORY AND COGNITIVE DISORDERS |
| JP7480131B2 (ja) | 2018-10-03 | 2024-05-09 | カビオン・インコーポレイテッド | （ｒ）－２－（４－イソプロピルフェニル）－ｎ－（１－（５－（２，２，２－トリフルオロエトキシ）ピリジン－２－イル）エチル）アセトアミドを使用した本態性振戦の処置 |
| CN118217178A (zh) | 2018-10-04 | 2024-06-21 | 宝洁公司 | 包含水不溶性固体有机化合物的个人护理组合物 |
| BR112021013766A2 (pt) | 2019-03-01 | 2021-09-21 | Flamel Ireland Limited | Composições de gama-hidroxibutirato com farmacocinética melhorada no estado alimentado |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
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| US20060003020A1 (en) * | 2004-03-11 | 2006-01-05 | The Regents Of The University Of Michigan | Anti-metastatic ability of mibefradil and gadolinium |
| CN100998566A (zh) * | 2006-12-30 | 2007-07-18 | 南京工业大学 | 替莫唑胺聚乳酸纳米微球与制剂及其制备方法 |
| US20080194669A1 (en) * | 2004-08-20 | 2008-08-14 | Gray Lloyd S | T Type Calcium Channel Blockers and the Treatment of Diseases |
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| US6251886B1 (en) * | 1998-12-07 | 2001-06-26 | Schering Corporation | Methods of using temozolomide in the treatment of cancers |
| US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| TW200538149A (en) * | 2004-05-20 | 2005-12-01 | Telik Inc | Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound |
| US20060000320A1 (en) * | 2004-06-30 | 2006-01-05 | Hutton William M | Ratchet wrench tool assembly for underground work and process of using |
| CA2576191C (en) * | 2004-08-20 | 2013-03-19 | University Of Virginia Patent Foundation | T type calcium channel inhibitors |
| WO2008141189A1 (en) * | 2007-05-09 | 2008-11-20 | Elixir Pharmaceuticals, Inc. | Ghrelin modulating compounds and combinations thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060003020A1 (en) * | 2004-03-11 | 2006-01-05 | The Regents Of The University Of Michigan | Anti-metastatic ability of mibefradil and gadolinium |
| US20080194669A1 (en) * | 2004-08-20 | 2008-08-14 | Gray Lloyd S | T Type Calcium Channel Blockers and the Treatment of Diseases |
| CN100998566A (zh) * | 2006-12-30 | 2007-07-18 | 南京工业大学 | 替莫唑胺聚乳酸纳米微球与制剂及其制备方法 |
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| SG10201402863PA (en) | 2014-10-30 |
| WO2010141842A2 (en) | 2010-12-09 |
| PL2437749T3 (pl) | 2018-04-30 |
| SG176678A1 (en) | 2012-01-30 |
| DK2437749T3 (da) | 2018-01-29 |
| ES2661216T3 (es) | 2018-03-28 |
| EP2437749A2 (en) | 2012-04-11 |
| MX344725B (es) | 2017-01-05 |
| EP2437749B8 (en) | 2018-02-21 |
| IL216443A (en) | 2016-11-30 |
| CN102458416A (zh) | 2012-05-16 |
| EP2437749B1 (en) | 2017-12-20 |
| KR20120030112A (ko) | 2012-03-27 |
| WO2010141842A3 (en) | 2011-04-21 |
| US20120088807A1 (en) | 2012-04-12 |
| JP2016028058A (ja) | 2016-02-25 |
| KR101905050B1 (ko) | 2018-10-08 |
| SG10201810806UA (en) | 2019-01-30 |
| MX2011012940A (es) | 2012-04-20 |
| EP2437749A4 (en) | 2013-04-17 |
| IL248482A0 (en) | 2016-12-29 |
| JP6159958B2 (ja) | 2017-07-12 |
| US20180228822A1 (en) | 2018-08-16 |
| ZA201108909B (en) | 2013-02-27 |
| JP2012528890A (ja) | 2012-11-15 |
| AU2010256442A1 (en) | 2012-01-19 |
| KR20170097237A (ko) | 2017-08-25 |
| CA2764499A1 (en) | 2010-12-09 |
| AU2010256442B2 (en) | 2016-07-21 |
| IL216443A0 (en) | 2012-02-29 |
| IL248482B (en) | 2020-08-31 |
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