CN106177891A - A kind of Chinese medicine composition and application thereof - Google Patents

A kind of Chinese medicine composition and application thereof Download PDF

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CN106177891A
CN106177891A CN201610837519.4A CN201610837519A CN106177891A CN 106177891 A CN106177891 A CN 106177891A CN 201610837519 A CN201610837519 A CN 201610837519A CN 106177891 A CN106177891 A CN 106177891A
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weight portion
chinese medicine
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rhizoma zingiberis
medicine composition
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王昌淦
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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Abstract

The present invention relates to a kind of Chinese medicine composition and application thereof, the raw material of this Chinese medicine composition is: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion.This Chinese medicine composition and the Chinese medicine preparation utilizing this Chinese medicine composition to prepare possess hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy.The present invention also provides for a kind of face mask of traditional Chinese medicine utilizing this Chinese medicine composition to prepare, this face mask of traditional Chinese medicine can be effectively improved face microcirculation, promote epidermis cell metabolism, possess hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, effect of pain relieving, the patient being especially suitable for having pox scar pox print on the face use.

Description

A kind of Chinese medicine composition and application thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly to one have hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, pain relieving The Chinese medicine composition of effect and application thereof.
Background technology
Human body skin is in lesion healing process, and collage synthesis metabolism loses normal tied mechanism, is continuously in Hyperfunction state so that collagen fiber hyperplasia, and generate grand go out normal skin, shape differs, the red matter of color is hard benign tumors, It is cicatrix.The technological means treating cicatrix in prior art includes laser method, compression therapeutic method, radioactive method, medicine method, rehabilitation Deng Therapeutic Method.But above-mentioned Therapeutic Method or poor effect, otherwise side effect is too big, and therefore, cicatrix patient is badly in need of a kind of effect The most more preferably, the Therapeutic Method that side effect is little.
Special needs to be pointed out is, cicatrix is if it occur that in parts such as scalps, can frequently result in the original hair in this position Growing system is destroyed.Prior art is treated the technological means of cicatrix not yet can give patient in this regard and effectively help.
In existing technical field of Chinese medicines, the prescription of hair growth promoting effect is had to be typically based on the Radix Polygoni Multiflori (Radix Polygoni Multiflori, Radix Polygoni Multiflori Preparata) Wanting effective ingredient, its one side hair-growing effects is unsatisfactory, and on the other hand its alopecia causing cicatrix there is no effect; The prescription having scar effect of dispelling then there are no the report of hair growth promoting effect.
Summary of the invention
In view of this, the present invention provides a kind of Chinese medicine composition, Chinese medicine preparation and face mask of traditional Chinese medicine.This Chinese medicine composition, in Medicine preparation and face mask of traditional Chinese medicine are respectively provided with hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy, and evident in efficacy.
In order to realize foregoing invention purpose, the present invention provides techniques below scheme:
A kind of have hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, the Chinese medicine composition of analgesic efficacy, its following weight portion of oil Raw material make: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion.
Rhizoma Zingiberis: for the dry rhizome of Zingiberaceae herbaceos perennial Rhizoma Zingiberis Recens.This product gas perfume (or spice) is special, and acrid in the mouth is peppery.Main performance: Pungent, heat.Return spleen, stomach, the heart, lung meridian.
Rhizoma Zingiberis Recens: for the fresh rhizome of Zingiberaceae herbaceos perennial Rhizoma Zingiberis Recens.This product gas fragrance, acrid in the mouth is peppery.Main performance: pungent, Temperature.Return lung, spleen, stomach warp.Effect: dispersing wind-cold, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough.
Fructus Evodiae: for Rutaceae machaka or arbor Fructus Evodiae, Shi Hu, the dry almost ripe fruit of thin hair Fructus Evodiae. Main product in Guizhou, Guangxi, the ground such as Hunan.8~fruit in November gather when not yet ftractureing.This product aroma is strong, acrid in the mouth is peppery and bitter. Main performance: pungent, bitter, heat.Slightly poisonous.Return liver, spleen, stomach warp.
Fructus Piperis: climb the dry near ripe of shape liana Fructus Piperis or mature fruit for Piperaceae is evergreen.This product gas fragrance, Acrid in the mouth is peppery.Main performance: pungent, heat.Return stomach, large intestine channel.
Cortex Cinnamomi: for the dry bark of Lauraceae aiphyllium Cortex Cinnamomi.This product fragrance is strong, and taste is sweet, peppery.Main performance: pungent, Sweet, heat.Return kidney, spleen, the heart, Liver Channel.Effect: mend fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.
Radix Ginseng Rubra: Radix Ginseng Rubra is the ripe articles for use of ginseng, and its processing method is: through infiltrating, clean, sort, steam, dry in the sun, drying Etc. operation, process.Radix Ginseng Rubra, during steaming, because heat treatment can occur chemical reaction, composition changes.Can give birth to The new composition that Cheng Shuican and Radix Ginseng the most all have, i.e. Radix Ginseng Rubra distinctive biological active substances G-Rh2, panaxytriol, maltol Deng.Radix Ginseng Rubra has strongly invigorating primordial QI, promoting the production of body fluid and inducing sedation of the mind etc. to act on, it is adaptable to palpitation with fear insomniac, body void person, heart failure, cardiogenic shock Deng.
Semen Allii Tuberosi: be again Semen Allii Tuberosi, Folium Allii tuberosi core.For the seed of liliaceous plant fragrant-flowered garlic, gas is special, and taste is peppery, and that chews has Folium Allii tuberosi taste. Main performance: acrid, sweet, warm.Return liver, kidney channel.Effect: liver and kidney tonifying, tonifying YANG controlling nocturnal emission with astringent drugs.
The Radix Astragali: for pulse family herbaceos perennial Radix Astagali or the dry root of Radix Astragali.This product feeble QI and taste is micro-sweet.
The compatible experiments of the above-mentioned Chinese medicine composition of the present invention:
First, prior art thinks that Rhizoma Zingiberis, Rhizoma Zingiberis Recens two medicine can not be used with, but the Chinese medicine composition of the present invention is simultaneously used Rhizoma Zingiberis and Rhizoma Zingiberis Recens, overcome the technology prejudice of those skilled in the art, achieve unforeseeable technique effect.Rhizoma Zingiberis and Rhizoma Zingiberis Recens There is difference on implantation methods: Rhizoma Zingiberis needs the growing way according to Rhizoma Zingiberis Recens constantly to earth up in planting process, Rhizoma Zingiberis Recens then need not training Soil, due to the difference of cultural method, causes chemical composition contained by Rhizoma Zingiberis and Rhizoma Zingiberis Recens to have obvious difference.The Chinese medicine composition of the present invention Thing is understanding based on the difference to Rhizoma Zingiberis and Rhizoma Zingiberis Recens when compatibility, and the two is used with originally, achieves good effect;
Second, the long small pox of human body skin, long carbuncle, eczema, itch, alopecia all relevant with dampness, cold alluvial, the present invention's Rhizoma Zingiberis in Chinese medicine composition, Rhizoma Zingiberis Recens, Fructus Evodiae can provide heat energy to skin, and then can promote that human body discharges dampness, from And make the Chinese medicine composition of the present invention have hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy;
3rd, Rhizoma Zingiberis Recens can also play the effect well dissipating, spreading, and can make the Chinese medicine composition effective ingredient of the present invention Though external or in the used time infiltration be delivered to target site;
4th, Fructus Evodiae is slightly poisonous, and the Rhizoma Zingiberis Recens in the Chinese medicine composition of the present invention can solve its mild toxicity, and side effect is little;
5th, Semen Allii Tuberosi, Radix Ginseng Rubra can promote the metabolism of Skin Cell, promote cell division, and then have hair growth promoting, educate Send out, allow hair become dense effect.
Present invention also offers the preparation method of a kind of Chinese medicine composition, its raw material is: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3 ~5 weight portions, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight Amount part, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion;
By described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, abundant mixing and get final product.
When Chinese medicinal components is crushed to the micropowder of 1500~3000 mesh, it is more beneficial for its interior effective ingredient first and releases Go out, second can be easier to be absorbed and used in external or interior used time.
Present invention also offers a kind of Chinese medicine preparation, including above-mentioned Chinese medicine composition and pharmaceutically acceptable adjuvant.
In some embodiments that the present invention provides, the Chinese medicine preparation that the present invention provides is interior preparation or external preparation, Described interior preparation includes granule, tablet, capsule, pill, soft extract, syrup, distillate medicinal water;Described external preparation includes powder Agent, solution, ointment, paste, tincture, gel.
In some embodiments of the invention, the preparation method of the ointment that the present invention provides, specially take following weight The raw material of part: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, meat Osmanthus 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion, with ultra-fine Pulverizer is crushed to 1500~3000 mesh, fully mixes;
Adding the Chinese medicine composition of above-mentioned mixing after vaseline infusion is become liquid, stirring and evenly mixing, after cooling and get final product.
When each Chinese medicinal components being crushed to 1500~3000 mesh micropowder states is added stirring and evenly mixing in vaseline, The effective ingredient of each Chinese medicinal components can quickly discharge to vaseline and fully mixed, and then makes all scholars prepared Woods ointment possess the hair growth promoting of Chinese medicine composition, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy.
Present invention also offers the preparation method of a kind of face mask of traditional Chinese medicine, comprise the steps:
Take the raw material of Chinese medicine of following weight portion: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight Part, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, The Radix Astragali 0.5~1 weight portion;By described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, fully add 2 times of weights after mixing The water of amount stirs evenly acquisition the concentrated liquid of tradition Chinese medicine;
Take face paper and be soaked in described the concentrated liquid of tradition Chinese medicine, to obtain final product.
The present invention provides a kind of Chinese medicine composition, Chinese medicine preparation and face mask of traditional Chinese medicine.This Chinese medicine composition and Chinese medicine preparation are equal Possess hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy.It is micro-that the face mask of traditional Chinese medicine that the present invention provides can be effectively improved face Circulation, promote epidermis cell metabolism, possess hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, effect of pain relieving, be especially suitable for face On have the patient that pox scar pox prints to use.
Detailed description of the invention
The invention discloses a kind of Chinese medicine composition, Chinese medicine preparation and face mask of traditional Chinese medicine, those skilled in the art can use for reference Present disclosure, is suitably modified technological parameter and realizes.Special needs to be pointed out is, all similar replacements and change are to this area skill Being apparent from for art personnel, they are considered as being included in the present invention.Method and the application of the present invention have been passed through relatively Good embodiment is described, and related personnel substantially can be to as herein described in without departing from present invention, spirit and scope Methods and applications are modified or suitably change and combine, and realize and apply the technology of the present invention.
The invention provides a kind of Chinese medicine composition, it is made up of the raw material of following weight portion:
Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, meat Osmanthus 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion.
Present invention also offers the preparation method of a kind of Chinese medicine composition, its raw material is:
Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, meat Osmanthus 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion;
By described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, abundant mixing and get final product.
Present invention also offers a kind of Chinese medicine preparation, including above-mentioned Chinese medicine composition and pharmaceutically acceptable adjuvant.
In some embodiments that the present invention provides, the Chinese medicine preparation that the present invention provides is interior preparation or external preparation;
Described interior preparation includes granule, tablet, capsule, pill, soft extract, syrup, distillate medicinal water;Described external preparation Including powder, solution, ointment, paste, tincture, gel.
In some embodiments of the invention, the preparation method of the ointment that the present invention provides, specially take following weight The raw material of part: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, meat Osmanthus 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion, with ultra-fine Pulverizer is crushed to 1500~3000 mesh, fully mixes;
Adding the Chinese medicine composition of above-mentioned mixing after vaseline infusion is become liquid, stirring and evenly mixing, after cooling and get final product.
As preferably, described raw material is 1:1~5 with the mass ratio of described vaseline.
Present invention also offers the preparation method of a kind of face mask of traditional Chinese medicine, comprise the steps:
Take the raw material of Chinese medicine of following weight portion: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight Part, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, The Radix Astragali 0.5~1 weight portion;By described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, fully add 2 times of weights after mixing The water of amount stirs evenly acquisition the concentrated liquid of tradition Chinese medicine;
Take face paper and be soaked in described the concentrated liquid of tradition Chinese medicine, to obtain final product.
The present invention provides a kind of Chinese medicine composition, Chinese medicine preparation and face mask of traditional Chinese medicine.This Chinese medicine composition and Chinese medicine preparation are equal Possess hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, analgesic efficacy.The obvious effective rate of the face mask of traditional Chinese medicine hair growth promoting that the present invention provides exists 92.78%, the obvious effective rate of scar of dispelling is 90.56%, and the obvious effective rate of antiinflammatory is 94.44%, and antipruritic obvious effective rate, 87.88%, disappears Swollen obvious effective rate is 94.44%, and the obvious effective rate of pain relieving is 88.89%.
In Chinese medicine composition, Chinese medicine preparation and face mask of traditional Chinese medicine that the present invention provides, raw material all can be buied by market.
Below in conjunction with embodiment, the present invention it is expanded on further:
Embodiment 1: the preparation of Chinese medicine composition
Accurately weigh Rhizoma Zingiberis 60g, Rhizoma Zingiberis Recens 30g, Fructus Evodiae 20g, Fructus Piperis 4g, Cortex Cinnamomi 4g, Radix Ginseng Rubra 5g, Semen Allii Tuberosi 5g, Radix Astragali 5g, By above-mentioned raw materials ultra-fine pulverizer disintegrating to 1500 mesh, abundant mixing and get final product.
Embodiment 2: the preparation of Chinese medicine composition
Accurately weigh Rhizoma Zingiberis 80g, Rhizoma Zingiberis Recens 50g, Fructus Evodiae 40g, Fructus Piperis 6g, Cortex Cinnamomi 6g, Radix Ginseng Rubra 10g, Semen Allii Tuberosi 15g, the Radix Astragali 10g, by above-mentioned raw materials ultra-fine pulverizer disintegrating to 3000 mesh, abundant mixing and get final product.
Embodiment 3: the preparation of Chinese medicine composition
Accurately weigh Rhizoma Zingiberis 70g, Rhizoma Zingiberis Recens 40g, Fructus Evodiae 30g, Fructus Piperis 5g, Cortex Cinnamomi 5g, Radix Ginseng Rubra 7.5g, Semen Allii Tuberosi 10g, the Radix Astragali 7,5g, by above-mentioned raw materials ultra-fine pulverizer disintegrating to 2000 mesh, abundant mixing and get final product.
Embodiment 4: the preparation of Chinese medicine ointment
Accurately weigh Rhizoma Zingiberis 60g, Rhizoma Zingiberis Recens 30g, Fructus Evodiae 20g, Fructus Piperis 4g, Cortex Cinnamomi 4g, Radix Ginseng Rubra 5g, Semen Allii Tuberosi 5g, Radix Astragali 5g, With ultra-fine pulverizer disintegrating to 1500 mesh, fully mix;
Vaseline infusion is become after liquid according to Chinese medicine composition: the ratio of vaseline mass ratio 1:1 adds above-mentioned mixing Chinese medicine composition, stirring and evenly mixing, after cooling and get final product.
Embodiment 5: the preparation of Chinese medicine ointment
Accurately weigh Rhizoma Zingiberis 80g, Rhizoma Zingiberis Recens 50g, Fructus Evodiae 40g, Fructus Piperis 6g, Cortex Cinnamomi 6g, Radix Ginseng Rubra 10g, Semen Allii Tuberosi 15g, the Radix Astragali 10g, with ultra-fine pulverizer disintegrating to 3000 mesh, fully mixes;
Vaseline infusion is become after liquid according to Chinese medicine composition: the ratio of vaseline mass ratio 1:5 adds above-mentioned mixing Chinese medicine composition, stirring and evenly mixing, after cooling and get final product.
Embodiment 6: the preparation of Chinese medicine ointment
Accurately weigh Rhizoma Zingiberis 70g, Rhizoma Zingiberis Recens 40g, Fructus Evodiae 30g, Fructus Piperis 5g, Cortex Cinnamomi 5g, Radix Ginseng Rubra 7.5g, Semen Allii Tuberosi 10g, the Radix Astragali 7,5g, by above-mentioned raw materials ultra-fine pulverizer disintegrating to 2000 mesh, fully mix;
Vaseline infusion is become after liquid according to Chinese medicine composition: the ratio of vaseline mass ratio 1:3 adds above-mentioned mixing Chinese medicine composition, stirring and evenly mixing, after cooling and get final product.
Embodiment 7: the preparation of Chinese medicine granules
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixes, conventionally, granulate, dry Dry, prepare Chinese medicine granules.
Embodiment 8: the preparation of Chinese medicine capsules
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, pelletizes, fill Capsule, prepares Chinese medicine capsules.
Embodiment 9: the preparation of Chinese medicinal tablet
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixes, conventionally, and tabletted, Film coating, prepares Chinese medicinal tablet.
Embodiment 10: the preparation of medicine pill
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, moulds preparation method or general system according to routine Method, prepares medicine pill.
Embodiment 11: the preparation of Chinese medicine decocting unguentum
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixes, conventionally, and sugar refinery or refining After honey, receive cream, prepare Chinese medicine decocting unguentum.
Embodiment 12: the preparation of Chinese materia medica syrup
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant such as sucrose etc., mixes, conventionally, Prepare Chinese materia medica syrup.
Embodiment 13: the preparation of Chinese medicine distillate medicinal water
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, and mixing, according to conventional distil-lation method, in preparing Distilled medicinal water agent.
Embodiment 14: the preparation of Chinese medicine powder
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixes, conventionally, and oven drying at low temperature Prepare Chinese medicine powder.
Embodiment 15: the preparation of Chinese medicine solution
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, prepares Chinese medicine Solution.
Embodiment 16: the preparation of Chinese medicine ointment
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, prepares Chinese medicine Ointment.
Embodiment 17: the preparation of cataplasm of tcm
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, prepares Chinese medicine Paste.
Embodiment 18: the preparation of Traditional Chinese medicine tincture preparation
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, prepares Chinese medicine Tincture.
Embodiment 19: the preparation of Chinese medicine gel
The Chinese medicine composition that Example 1 to 3 prepares, adds customary adjuvant, mixing, conventionally, prepares Chinese medicine Gel.
Embodiment 20: the preparation of face mask of traditional Chinese medicine
The water that the Chinese medicine composition that embodiment 1 to 3 prepares adds 2 times of weight is stirred evenly acquisition the concentrated liquid of tradition Chinese medicine, takes facial film Paper is soaked in this concentrated solution, to obtain final product.
Embodiment 21: acute toxicity maximum resistance test
It is resistance to that the Chinese medicine preparation that according to embodiments of the present invention prepared by 4 to embodiment 19 carries out acute toxicity maximum in animal body Being put to the test, the day maximum tolerated dose being administered mouse stomach is 400 times of the clinical consumption per day of adult, does not observes under this dosage The toxic reaction of the Chinese medicine preparation that the preparation method that the present invention provides is made.
Embodiment 22: long term toxicity test
The Chinese medicine preparation of the embodiment of the present invention 4 to embodiment 19 preparation is carried out long term toxicity examination in 6 months in animal body Testing, every day is administered to rat oral gavage, and dosage is respectively equivalent to be grown up 100 times, 50 times, 20 times of clinical day dose.Observe item Mesh is include General observation and the complete detection that includes including hematological examination 29.Result shows, three dosages are the most not Obvious adverse reaction occurs, shows that the Chinese medicine preparation of 4 to embodiment 19 preparation according to embodiments of the present invention for Clinical practice is Safety.
Embodiment 23: long-term clinical trials
The Chinese medicine composition that for oral administration or external application embodiment of the present invention 1 to 20 provides, be provided with significant hair growth promoting, scar of dispelling, Antiinflammatory, antipruritic, detumescence, analgesic efficacy.
The Chinese medicine preparation of the embodiment of the present invention 7 to embodiment 13 preparation for oral administration, a 3-4 grain (sheet/ball), 3 times on the one, even Take two weeks;Or the Chinese medicine preparation of the external embodiment of the present invention 4 to embodiment 6, embodiment 14 to embodiment 19 preparation, clinical sight Examine, do not find obvious adverse reaction.Curative effect determinate standard performs with reference to " Clinical Researches of New Drugs guideline " version in 2002.
Curative effect determinate standard:
Basic healing: hair growth promoting > 90%, scar > 90% of dispelling, antiinflammatory > 90%, antipruritic > 90%, subside a swelling > 90%, pain relieving > 90%;
Effective: hair growth promoting > 60%, scar > 60% of dispelling, antiinflammatory > 60%, antipruritic > 60%, subside a swelling > 60%, pain relieving > 60%;
Taking a turn for the better: hair growth promoting > 30%, scar > 30% of dispelling, antiinflammatory > 30%, antipruritic > 30%, subside a swelling > 30%, pain relieving > 30%;
Invalid: hair growth promoting < 30%, scar < 30% of dispelling, antiinflammatory < 30%, antipruritic < 30%, subside a swelling < 30%, pain relieving < 30%;
Effective percentage=(substantially curing number of cases+effective number of cases+improvement number of cases)/total number of cases × 100%;
Obvious effective rate=(substantially curing number of cases+effective number of cases)/total number of cases × 100%
Table 1 clinical therapeutic efficacy
Clinical therapeutic efficacy shows, the obvious effective rate of the Chinese medicine preparation hair growth promoting that the embodiment of the present invention 4 to embodiment 19 provides exists 92.78%, the obvious effective rate of scar of dispelling is 90.56%, and the obvious effective rate of antiinflammatory is 94.44%, and antipruritic obvious effective rate, 87.88%, disappears Swollen obvious effective rate is 94.44%, and the obvious effective rate of pain relieving is 88.89%.
Embodiment 24: the face mask of traditional Chinese medicine therapeutic effect that the present invention provides
Case 1: Xiamen Mrs Cai, 35 years old, has the cicatrix of each 1 cm of a length and width, anaphalantiasis at cicatrix at eyebrow. Once a day, the facial film of each application embodiment of the present invention 20 preparation 30 minutes to 60 minutes, one week is a course for the treatment of.
First course for the treatment of terminates rear cicatrix and begins to level off, and color is thin out;Second course for the treatment of terminates hair growth at rear cicatrix System recovery function, begins with the growth of sparse eyebrow;3rd course for the treatment of terminates rear cicatrix lump and substantially disappears, color and surrounding skin Skin is close, and the density of eyebrow is similar with surrounding eyebrow, does not sees there is cicatrix from the most substantially.
Case 2: Quanzhou Mr. Lin, 20 years old, comedo was more serious on the face, and many places suppuration, infection, inflammation, if not in time Correct treatment will leave serious pox scar on the face.
Once a day, the facial film of each application embodiment of the present invention 20 preparation 30 minutes to 60 minutes, one week is a treatment Journey.
Terminate first course for the treatment of that the facial skin that rear comedo causes suppurates, infects, inflammation is obviously controlled, and emits pox Local pressing is without pain;The second to four course for the treatment of terminates rear facial skin and becomes smooth, smooth, leaves over without obvious pox scar.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (6)

1. one kind have hair growth promoting, scar of dispelling, antiinflammatory, antipruritic, detumescence, the Chinese medicine composition of analgesic efficacy, it is characterised in that its raw material For: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4 ~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion.
2. the preparation method of a Chinese medicine composition as claimed in claim 1, it is characterised in that its raw material is: Rhizoma Zingiberis 6~8 Weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion;
By described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, abundant mixing and get final product.
3. a Chinese medicine preparation, it is characterised in that include Chinese medicine composition as claimed in claim 1 and pharmaceutically acceptable Adjuvant.
Chinese medicine preparation the most according to claim 3, it is characterised in that it is interior preparation or external preparation, described interior use Preparation is selected from granule, tablet, capsule, pill, soft extract, syrup, distillate medicinal water;Described external preparation selected from powder, solution, Ointment, paste, tincture, gel.
5. the preparation method of as claimed in claim 4 ointment, it is characterised in that take the raw material of following weight portion: Rhizoma Zingiberis 6~8 Weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, Fructus Piperis 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion, with ultra-fine pulverizer disintegrating to 1500~ 3000 mesh, fully mix;
Adding the Chinese medicine composition of above-mentioned mixing after vaseline infusion is become liquid, stirring and evenly mixing, after cooling and get final product.
6. the preparation method of a face mask of traditional Chinese medicine, it is characterised in that comprise the steps:
Take the raw material of Chinese medicine of following weight portion: Rhizoma Zingiberis 6~8 weight portion, Rhizoma Zingiberis Recens 3~5 weight portion, Fructus Evodiae 2~4 weight portion, recklessly Green pepper 0.4~0.6 weight portion, Cortex Cinnamomi 0.4~0.6 weight portion, Radix Ginseng Rubra 0.5~1 weight portion, Semen Allii Tuberosi 0.5~1.5 weight portion, the Radix Astragali 0.5~1 weight portion;2 times of weight are added after described raw material ultra-fine pulverizer disintegrating to 1500~3000 mesh, fully mixing Water stirs evenly acquisition the concentrated liquid of tradition Chinese medicine;
Take face paper and be soaked in described the concentrated liquid of tradition Chinese medicine, to obtain final product.
CN201610837519.4A 2016-09-21 2016-09-21 A kind of Chinese medicine composition and application thereof Pending CN106177891A (en)

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Publication number Priority date Publication date Assignee Title
CN113662893A (en) * 2021-08-20 2021-11-19 中山中研化妆品有限公司 Temperature-sensitive mask and preparation method thereof

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CN103655257A (en) * 2013-05-14 2014-03-26 广东太阳神集团有限公司 Chinese medicine hair nourishing shampoo and preparation method thereof
CN103977371A (en) * 2014-05-12 2014-08-13 谢桂斌 Medicament for treating alopecia
CN104353002A (en) * 2014-10-08 2015-02-18 天津科丝美特生物科技有限公司 Hair loss prevention and hair growth plant liquid
CN105148234A (en) * 2015-09-23 2015-12-16 黄名珠 Medicine for treating alopecia

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Publication number Priority date Publication date Assignee Title
CN103007249A (en) * 2013-01-17 2013-04-03 赵海荣 Scar revision ointment
CN103655257A (en) * 2013-05-14 2014-03-26 广东太阳神集团有限公司 Chinese medicine hair nourishing shampoo and preparation method thereof
CN103977371A (en) * 2014-05-12 2014-08-13 谢桂斌 Medicament for treating alopecia
CN104353002A (en) * 2014-10-08 2015-02-18 天津科丝美特生物科技有限公司 Hair loss prevention and hair growth plant liquid
CN105148234A (en) * 2015-09-23 2015-12-16 黄名珠 Medicine for treating alopecia

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113662893A (en) * 2021-08-20 2021-11-19 中山中研化妆品有限公司 Temperature-sensitive mask and preparation method thereof

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