CN106177790A - A kind of capsule treating tumor and preparation method thereof - Google Patents

A kind of capsule treating tumor and preparation method thereof Download PDF

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Publication number
CN106177790A
CN106177790A CN201610743552.0A CN201610743552A CN106177790A CN 106177790 A CN106177790 A CN 106177790A CN 201610743552 A CN201610743552 A CN 201610743552A CN 106177790 A CN106177790 A CN 106177790A
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parts
radix
supernatant
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tumor
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王建斌
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/066—Clavicipitaceae
    • A61K36/068—Cordyceps
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    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention discloses a kind of capsule treating tumor and preparation method thereof, a kind of capsule treating tumor of the present invention, it is made up of the following component of weight portion meter: Radix Scutellariae 25 50 parts, Ganoderma 22 38 parts, Radix Pseudostellariae 22 38 parts, Radix Codonopsis 20 38 parts, Semen Cuscutae 8 15 parts, Fructus Forsythiae 12 14 parts, gram Flos Chrysanthemi 58 parts, 58 parts of Radix Glycyrrhizae, Cordyceps 35 parts, Herba Hedyotidis Diffusae 30 60 parts, art 39 parts, Herba Scutellariae Barbatae 25 50 parts, Herba Dendrobii 15 35 parts, Pericarpium Citri Reticulatae 10 12 parts, Periostracum Serpentis 35 parts.Tumor cell is killed in present invention suppression, reduces cancerous protuberance patient suffering, effectively extends their life-span.

Description

A kind of capsule treating tumor and preparation method thereof
Technical field
The present invention relates to therapeutic field of tumor, be specifically related to a kind of capsule treating tumor and preparation method thereof.
Background technology
Radiotherapy and chemotherapy are the essential therapeutic arsenals of malignant tumor, but its toxicity is the biggest.Mesh The anti-tumor medicine thing of front Clinical practice all has toxic and side effects in various degree, and they are while killing tumor cell, again Kill the cell of normal structure, especially kill blood, lymphocyte etc. that in human body, growth promoter is vigorous.Cancer therapy drug The mode classification of untoward reaction is a lot, and according to the cancer therapy drug impact on body different system, untoward reaction mainly has blood poison Property, gastrointestinal toxicity, mucosa lesions, liver toxicity, nephrotoxicity etc..
On the basis of traditional medicine determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, for common multiple pulmonary carcinoma, gastric cancer, the treatment of colorectal cancer, in routine On the basis for the treatment of, lack of appetite abdominal distention that during being conceived to tumor chemoradiotherapy, patient occurs, the dependency disease such as indigestion and loss of appetite, sweating is weak Disease, establishes emphasis disease kind diagnosis and treatment specification, sums up and refines the obvious proved recipe of several clinical curative effect and feature therapies, promotes, The attenuation synergistic of the raising of patients ' life quality, the control of symptom and chemotherapeutics is achieved very big effect, real by clinic Summary after trampling, treats peri-operation period, encloses the controlling extent pair of the quality of life of phase patient, clinical symptoms between chemotherapy stage, radiotherapy Curative effect and prognosis play critical effect.
Summary of the invention
For solving the problems referred to above, it is an object of the invention to provide capsule and the preparation side thereof of a kind of eutherapeutic treatment tumor Method.
For realizing above-mentioned technical purpose, the technical solution used in the present invention is as follows: a kind of glue treating tumor of the present invention Capsule, is made up of the following component of weight portion meter:
Further, it is made up of the following component of weight portion meter:
The preparation method of the capsule for the treatment of tumor of the present invention, comprises the steps:
(1) it is dried after Radix Pseudostellariae, Radix Codonopsis, Radix Scutellariae, Ganoderma, Pericarpium Citri Reticulatae being weighed up by weight ratio, in dried Medicine raw material is crushed to the microgranule of 400-600 mesh by super micron mill；
(2) Radix Pseudostellariae microgranule, Radix Codonopsis microgranule, Radix Scutellariae microgranule, Ganoderma microgranule, Pericarpium Citri Reticulatae microgranule are separately added into 80% concentration After the amount of ethanol 5-30 times, fully mixing, extract 5-7 hour, under room temperature, stand 24-48 hour, respectively obtain five kinds of microgranules Supernatant extracting solution and medicinal residues；
(3) take the medicinal residues of three kinds of microgranules in step (2), add the ethanol 5-30 times amount of 80% concentration, fully after mixing, carry Take 3-7 hour, under room temperature, stand 24-48 hour, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules；
(4) take the medicinal residues of five kinds of microgranules in step (3), add the ethanol 5-30 times amount of 80% concentration, fully after mixing, carry Taking 3-7 hour, under room temperature, stand 24-48 hour, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules, medicinal residues discard；
(5) the Radix Pseudostellariae supernatant that step (2), (3), (4) obtained, Radix Codonopsis supernatant, Radix Scutellariae supernatant, Ganoderma supernatant Liquid, Pericarpium Citri Reticulatae supernatant merge respectively, are filtered to remove residual impurity, obtain the clarified supernatant of five kinds of raw material of Chinese medicine, then to five kinds The clarified supernatant of raw material of Chinese medicine is separately recovered ethanol, and being concentrated into relative density respectively is 1.10-1.45 extractum, powdered extract, Pulverize, cross 40-60 mesh sieve, obtain dry extract, by five kinds of dry extract mix homogeneously；
(6) by Semen Cuscutae, Fructus Forsythiae, gram Flos Chrysanthemi, Radix Glycyrrhizae, Cordyceps, Herba Hedyotidis Diffusae, art, Herba Scutellariae Barbatae, Herba Dendrobii, Serpentis After skin mixing, after decocting, filter, concentrating, obtaining relative density is 1.2-1.5 extractum；
(7) by extractum and the extractum mixing of step (6) gained of step (5) gained, adjuvant is added, through pelletizing, be dried, going out Bacterium, prepares the capsule for the treatment of tumor.
Further, in step (5), the temperature of described extractum is 50-60 DEG C.
Further, in step (6), the temperature of described extractum is 50-60 DEG C.
Beneficial effect: tumor cell is killed in present invention suppression, reduces cancerous protuberance patient suffering, effectively extends their life-span. The clinical efficacy of the drug on tumor patient of the present invention understands, and therapeutic effect of the present invention is notable, and side effect is little, with the raw marrow of the kidney invigorating, The method that blood circulation promoting and dispersing pathogen accumulation, blood stasis dispelling are had one's ideas straightened out, can effectively treat malignant tumor.
Detailed description of the invention
Further illustrate the present invention by the following examples.It should be understood that these embodiments are the explainations of the present invention And citing, limit the scope of the present invention the most in any form.
Embodiment 1
A kind of capsule treating tumor of the present invention, is made up of the following component of weight portion meter:
The preparation method of the capsule for the treatment of tumor of the present invention, comprises the steps:
(1) it is dried after Radix Pseudostellariae, Radix Codonopsis, Radix Scutellariae, Ganoderma, Pericarpium Citri Reticulatae being weighed up by weight ratio, in dried Medicine raw material is crushed to the microgranule of 500 mesh by super micron mill；
(2) Radix Pseudostellariae microgranule, Radix Codonopsis microgranule, Radix Scutellariae microgranule, Ganoderma microgranule, Pericarpium Citri Reticulatae microgranule are separately added into 80% concentration After the amount that ethanol is 20 times, fully mixing, extract 5-7 hour, under room temperature, stand 24-48 hour, respectively obtain the upper of five kinds of microgranules Clear extracting solution and medicinal residues；
(3) take the medicinal residues of three kinds of microgranules in step (2), add ethanol 5 times amount of 80% concentration, fully after mixing, extract 7 Hour, under room temperature, stand 40 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules；
(4) take the medicinal residues of five kinds of microgranules in step (3), add ethanol 5 times amount of 80% concentration, fully after mixing, extract 3 Hour, under room temperature, standing 48 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules, medicinal residues discard；
(5) the Radix Pseudostellariae supernatant that step (2), (3), (4) obtained, Radix Codonopsis supernatant, Radix Scutellariae supernatant, Ganoderma supernatant Liquid, Pericarpium Citri Reticulatae supernatant merge respectively, are filtered to remove residual impurity, obtain the clarified supernatant of five kinds of raw material of Chinese medicine, then to five kinds The clarified supernatant of raw material of Chinese medicine is separately recovered ethanol, and being concentrated into relative density respectively is 1.10-1.45 extractum, powdered extract, Pulverize, cross 40-60 mesh sieve, obtain dry extract, by five kinds of dry extract mix homogeneously；The temperature of described extractum is 50-60 DEG C.
(6) by Semen Cuscutae, Fructus Forsythiae, gram Flos Chrysanthemi, Radix Glycyrrhizae, Cordyceps, Herba Hedyotidis Diffusae, art, Herba Scutellariae Barbatae, Herba Dendrobii, Serpentis After skin mixing, after decocting, filter, concentrating, obtaining relative density is 1.2 extractum；The temperature of described extractum is 50 DEG C.
(7) by extractum and the extractum mixing of step (6) gained of step (5) gained, adjuvant is added, through pelletizing, be dried, going out Bacterium, prepares the capsule for the treatment of tumor.
Embodiment 2
A kind of capsule treating tumor of the present invention, is made up of the following component of weight portion meter:
The preparation method of the capsule for the treatment of tumor of the present invention, comprises the steps:
In step (1), it is dried after Radix Pseudostellariae, Radix Codonopsis, Radix Scutellariae, Ganoderma, Pericarpium Citri Reticulatae are weighed up by weight ratio, will be dry Raw material of Chinese medicine after dry is crushed to the microgranule of 600 mesh by super micron mill；
In step (2), Radix Pseudostellariae microgranule, Radix Codonopsis microgranule, Radix Scutellariae microgranule, Ganoderma microgranule, Pericarpium Citri Reticulatae microgranule are separately added into After the amount of the ethanol of 80% concentration 30 times, fully mixing, extract 5-7 hour, under room temperature, stand 24-48 hour, respectively obtain five Plant supernatant extracting solution and the medicinal residues of microgranule；
In step (3), take the medicinal residues of three kinds of microgranules in step (2), add ethanol 20 times amount of 80% concentration, the most mixed After even, extract 6 hours, under room temperature, stand 24 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules；
In step (4), take the medicinal residues of five kinds of microgranules in step (3), add ethanol 20 times amount of 80% concentration, the most mixed After even, extracting 3 hours, under room temperature, stand 38 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules, medicinal residues discard；
In step (5), Radix Pseudostellariae supernatant that step (2), (3), (4) are obtained, Radix Codonopsis supernatant, Radix Scutellariae supernatant Liquid, Ganoderma supernatant, Pericarpium Citri Reticulatae supernatant merge respectively, are filtered to remove residual impurity, obtain the clarified supernatant of five kinds of raw material of Chinese medicine, Then the clarified supernatant of five kinds of raw material of Chinese medicine being separately recovered ethanol, being concentrated into relative density respectively is 1.45 extractum, is dried Extractum, pulverizes, and crosses 40-60 mesh sieve, obtains dry extract, by five kinds of dry extract mix homogeneously；The temperature of described extractum is 50-60 ℃。
In step (6), by Semen Cuscutae, Fructus Forsythiae, gram Flos Chrysanthemi, Radix Glycyrrhizae, Cordyceps, Herba Hedyotidis Diffusae, art, half After lotus, Herba Dendrobii, Periostracum Serpentis mixing, after decocting, filter, concentrating, obtaining relative density is 1.5 extractum；The temperature of described extractum is 55℃。
In step (7), by extractum and the extractum mixing of step (6) gained of step (5) gained, add adjuvant, through system Grain, dry, sterilizing, prepare the capsule for the treatment of tumor.
Embodiment 3
A kind of capsule treating tumor of the present invention, is made up of the following component of weight portion meter:
The preparation method of the capsule for the treatment of tumor of the present invention, comprises the steps:
In step (1), it is dried after Radix Pseudostellariae, Radix Codonopsis, Radix Scutellariae, Ganoderma, Pericarpium Citri Reticulatae are weighed up by weight ratio, will be dry Raw material of Chinese medicine after dry is crushed to the microgranule of 400 mesh by super micron mill；
In step (2), Radix Pseudostellariae microgranule, Radix Codonopsis microgranule, Radix Scutellariae microgranule, Ganoderma microgranule, Pericarpium Citri Reticulatae microgranule are separately added into The amount of the ethanol of 80% concentration 5 times, fully after mixing, extracts 5-7 hour, under room temperature, stands 24 hours, respectively obtain five kinds micro- The supernatant extracting solution of grain and medicinal residues；
In step (3), take the medicinal residues of three kinds of microgranules in step (2), add ethanol 30 times amount of 80% concentration, the most mixed After even, extract 7 hours, under room temperature, stand 48 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules；
In step (4), take the medicinal residues of five kinds of microgranules in step (3), add ethanol 30 times amount of 80% concentration, the most mixed After even, extracting 5 hours, under room temperature, stand 24 hours, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules, medicinal residues discard；
In step (5), Radix Pseudostellariae supernatant that step (2), (3), (4) are obtained, Radix Codonopsis supernatant, Radix Scutellariae supernatant Liquid, Ganoderma supernatant, Pericarpium Citri Reticulatae supernatant merge respectively, are filtered to remove residual impurity, obtain the clarified supernatant of five kinds of raw material of Chinese medicine, Then the clarified supernatant of five kinds of raw material of Chinese medicine being separately recovered ethanol, being concentrated into relative density respectively is 1.10 extractum, is dried Extractum, pulverizes, and crosses 40 mesh sieves, obtains dry extract, by five kinds of dry extract mix homogeneously；The temperature of described extractum is 50 DEG C.
In step (6), by Semen Cuscutae, Fructus Forsythiae, gram Flos Chrysanthemi, Radix Glycyrrhizae, Cordyceps, Herba Hedyotidis Diffusae, art, half After lotus, Herba Dendrobii, Periostracum Serpentis mixing, after decocting, filter, concentrating, obtaining relative density is 1.3 extractum；The temperature of described extractum is 60℃。
Clinical treatment example 1
Pulmonary carcinoma:
Wang, man, 39 years old, certain retired employees of factory, check because of chest discomfort to certain First People's Hospital of city in August, 2009 It is diagnosed as central type carcinoma of lung, and forms a large amount of hydrothorax and cause left shoulder arm pain unbearably painful.Intend operation, due to this economic bar of patient Part is bad, and 20,000 yuan of Operation Fees to be received by hospital and my economic condition is the poorest, therefore fails to perform the operation.Through our unit, colleague's introduction is taken This medicine, after treating 6 months, CT check display pulmonary masses is wholly absent.The most 8 these patients of year are still alive and live Quality is fine, has reached tumor patient and has cured the treatment standard surviving recoveries from illness in 6 years.
Clinical treatment example 2
Pulmonary carcinoma:
In certain: certain company worker, in February, 2000 does routine physical examination in state hospital and finds that right lung has about 5mm lump, when Time chest once by microtrauma, state hospital make antiinflammatory process, check its lump after three months and expand 24mm to, biopsy is that lung is little carefully Born of the same parents' cancer, through taking medicine two weeks of the present invention, improvement sign is obvious.
Clinical treatment example 3
Mammary gland tumor:
Wang: female, workman, 42 years old, people from Jing Zhou, Hubei.Because mammary gland tumor to certain the People's Hospital of city checks that being diagnosed as mammary gland increases Raw.29mmx27mm, is gradually reduced through taking medicine lump of the present invention, and within 4 months, lump is wholly absent.
The clinical efficacy of the drug on tumor patient of the present invention understands, and therapeutic effect of the present invention is notable, and side effect is little, to mend The method that the raw marrow of kidney, blood circulation promoting and dispersing pathogen accumulation, blood stasis dispelling are had one's ideas straightened out, can effectively treat malignant tumor.
The ultimate principle of the present invention, principal character and advantages of the present invention have more than been shown and described.The technology of the industry Personnel, it should be appreciated that the present invention is not restricted to the described embodiments, simply illustrating this described in above-described embodiment and description The principle of invention, without departing from the spirit and scope of the present invention, the present invention also has various changes and modifications, the present invention Claimed scope is defined by appending claims, description and equivalent thereof.

Claims (5)

1. the capsule treating tumor, it is characterised in that be made up of the following component of weight portion meter:
Radix Scutellariae 25-50 part,
Ganoderma 22-38 part,
Radix Pseudostellariae 22-38 part,
Radix Codonopsis 20-38 part,
Semen Cuscutae 8-15 part,
Fructus Forsythiae 12-14 part,
Gram Flos Chrysanthemi 5-8 part,
Radix Glycyrrhizae 5-8 part,
Cordyceps 3-5 part,
Herba Hedyotidis Diffusae 30-60 part,
Art 3-9 part,
Herba Scutellariae Barbatae 25-50 part,
Herba Dendrobii 15-35 part,
Pericarpium Citri Reticulatae 10-12 part,
Periostracum Serpentis 3-5 part.
The capsule for the treatment of tumor the most according to claim 1, it is characterised in that be made up of the following component of weight portion meter:
Radix Scutellariae 30 parts,
Ganoderma 23 parts,
Radix Pseudostellariae 25 parts,
Radix Codonopsis 30 parts,
Semen Cuscutae 15 parts,
Fructus Forsythiae 14 parts
Gram Flos Chrysanthemi 6 parts,
8 parts of Radix Glycyrrhizae,
Cordyceps 3 parts,
Herba Hedyotidis Diffusae 40 parts,
Art 7 parts,
Herba Scutellariae Barbatae 30 parts,
Herba Dendrobii 30 parts,
Pericarpium Citri Reticulatae 12 parts,
Periostracum Serpentis 3 parts.
3. the preparation method of the capsule of the treatment tumor described in claim 1 or 2, it is characterised in that comprise the steps:
(1) it is dried after Radix Pseudostellariae, Radix Codonopsis, Radix Scutellariae, Ganoderma, Pericarpium Citri Reticulatae being weighed up by weight ratio, by former for dried Chinese medicine Material is crushed to the microgranule of 400-600 mesh by super micron mill；
(2) Radix Pseudostellariae microgranule, Radix Codonopsis microgranule, Radix Scutellariae microgranule, Ganoderma microgranule, Pericarpium Citri Reticulatae microgranule are separately added into the second of 80% concentration After the amount of alcohol 5-30 times, fully mixing, extract 5-7 hour, under room temperature, stand 24-48 hour, respectively obtain five kinds of microgranules Supernatant extracting solution and medicinal residues；
(3) take the medicinal residues of three kinds of microgranules in step (2), add the ethanol 5-30 times amount of 80% concentration, fully after mixing, extract 3-7 hour, under room temperature, stand 24-48 hour, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules；
(4) take the medicinal residues of five kinds of microgranules in step (3), add the ethanol 5-30 times amount of 80% concentration, fully after mixing, extract 3-7 hour, under room temperature, standing 24-48 hour, respectively obtain supernatant extracting solution and the medicinal residues of five kinds of microgranules, medicinal residues discard；
(5) the Radix Pseudostellariae supernatant that step (2), (3), (4) obtained, Radix Codonopsis supernatant, Radix Scutellariae supernatant, Ganoderma supernatant, Pericarpium Citri Reticulatae supernatant merges respectively, is filtered to remove residual impurity, obtains the clarified supernatant of five kinds of raw material of Chinese medicine, then to five kinds of Chinese medicines The clarified supernatant of raw material is separately recovered ethanol, and being concentrated into relative density respectively is 1.10-1.45 extractum, powdered extract, pulverizes, Cross 40-60 mesh sieve, obtain dry extract, by five kinds of dry extract mix homogeneously；
(6) Semen Cuscutae, Fructus Forsythiae, gram Flos Chrysanthemi, Radix Glycyrrhizae, Cordyceps, Herba Hedyotidis Diffusae, art, Herba Scutellariae Barbatae, Herba Dendrobii, Periostracum Serpentis are mixed After conjunction, after decocting, filter, concentrating, obtaining relative density is 1.2-1.5 extractum；
(7) by extractum and the extractum mixing of step (6) gained of step (5) gained, adjuvant is added, through granulation, dry, sterilizing, Prepare the capsule for the treatment of tumor.
The preparation method of the capsule for the treatment of tumor the most according to claim 3 and preparation method thereof, it is characterised in that: in step Suddenly, in (5), the temperature of described extractum is 50-60 DEG C.
The preparation method of the capsule for the treatment of tumor the most according to claim 3 and preparation method thereof, it is characterised in that: in step Suddenly, in (6), the temperature of described extractum is 50-60 DEG C.
CN201610743552.0A 2016-08-29 2016-08-29 A kind of capsule treating tumor and preparation method thereof Pending CN106177790A (en)

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Publication number Priority date Publication date Assignee Title
CN108079197A (en) * 2018-01-18 2018-05-29 张涉应 A kind of anti-tumor drug and preparation method
CN108355100A (en) * 2018-05-28 2018-08-03 北京雄九医学研究院 A kind of Chinese medicine preparation and its preparation process of anticancer
CN113813347A (en) * 2021-10-22 2021-12-21 庞中龙 Preparation method and process of compound paclitaxel anti-tumor capsule tablet

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CN105412818A (en) * 2015-12-05 2016-03-23 张秀凤 Medicine for treating tumors and preparation method thereof
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108079197A (en) * 2018-01-18 2018-05-29 张涉应 A kind of anti-tumor drug and preparation method
CN108355100A (en) * 2018-05-28 2018-08-03 北京雄九医学研究院 A kind of Chinese medicine preparation and its preparation process of anticancer
CN113813347A (en) * 2021-10-22 2021-12-21 庞中龙 Preparation method and process of compound paclitaxel anti-tumor capsule tablet

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Application publication date: 20161207