CN106177313B - War wound ointment for promoting muscle growth and preparation method thereof - Google Patents

War wound ointment for promoting muscle growth and preparation method thereof Download PDF

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CN106177313B
CN106177313B CN201610755237.XA CN201610755237A CN106177313B CN 106177313 B CN106177313 B CN 106177313B CN 201610755237 A CN201610755237 A CN 201610755237A CN 106177313 B CN106177313 B CN 106177313B
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gelatin
sesame oil
muscle growth
blood
promoting muscle
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丁望
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Abstract

The present invention relates to traditional Chinese herb medicines and preparation method thereof.Belong to field of traditional Chinese medicine preparation, more specifically to a kind of war wound ointment for promoting muscle growth and preparation method thereof for War injury field.It is made of sesame oil, olibanum, myrrh, dragon's blood, catechu, rosin, borneol, camphor, donkey-hide gelatin, gelatin, beeswax reasonable compatibility.It the treatment of diseases such as festers suitable for the soft tissue lacerated wound of war (wound) wound, defect of skin, infection, bleeding, later period water outlet.

Description

War wound ointment for promoting muscle growth and preparation method thereof
Technical field
The present invention relates to traditional Chinese herb medicines and preparation method thereof.Belong to field of traditional Chinese medicine preparation, more specifically to a kind of use War wound ointment for promoting muscle growth and preparation method thereof in War injury field.
Background technique
War injury cause soft tissue injury clinic common phenomenon is: tissue tearing, damage, infection etc..Clinic mostly uses operation Treatment, gently then easily more, heavy then difficult multiple, extension is not cured, with the passing of time at sore.Effective hemostasis of early stage, analgesic, detumescence, myogenic are treatments Key, and prevention chronic ulcer formed key.The surface of a wound for clear sore suture of performing the operation either is taken after wound or is not taken The surface of a wound of operative treatment, the thorough healing of wound is mainly by self self-healing.The field, which lacks, can speed up wound healing, prevents and treats and burst The active drug that ulcer is formed.Especially damage serious, defect is larger, infection it is serious more must such drug partner treatment, effectively plus Fast wound repair is to save being effectively ensured for fighting capacity and productivity.Clinic is common all kinds of putrefaction-removing granulation-promoting pastes, mostly for routed The treatment in ulcer face, and mostly black plaster, hard plaster need baking to soften, measure shearing on demand before use, cumbersome, inconvenient fast Speed expansion uses, and the scope of application is narrow.Time is life, and War injury treatment, which needs most, races against time, and needs to meet " short " Rigors such as (used time is short) " letter " (easy to operate) " just " (easy to use) " testing " (curative for effect), rapid deployment can be protected effectively Deposit fighting capacity and productivity.
Summary of the invention
Present invention aim to address the above problem in War injury field or defect, provide a kind of war wound ointment for promoting muscle growth and its Preparation method, meet War injury effectively stop blooding, relieve pain, reducing swelling, myogenic, accelerate wound healing requirement, prevent and treat trauma surface infestation, fit For each period of Wound treating after War injury, sufficiently meet the harsh of " short " " letter " " just " " testing " that war wound needs at this stage Demand.
War wound ointment for promoting muscle growth of the present invention, is made of the ingredient of following parts by weight
Sesame oil 50-100, olibanum 5-10, myrrh 3-12, dragon's blood 5-10, catechu 3-5, rosin 3-5, borneol 1-5, camphor 1- 3, donkey-hide gelatin 1-3, gelatin 1-3, beeswax 1-5.
Its excellent parts by weight matches ratio are as follows: sesame oil 50, olibanum 5, myrrh 3, dragon's blood 5, catechu 3, rosin 3, borneol 1, camphor 1, donkey-hide gelatin 1, gelatin 1, beeswax 1.
Another preferred weight number proportion are as follows: sesame oil 100, olibanum 10, myrrh 12, dragon's blood 10, catechu 5, rosin 5, borneol 5, camphor 3, donkey-hide gelatin 3, gelatin 3, beeswax 5.
The preparation method of the war wound ointment for promoting muscle growth, includes the following steps:
A) taking olibanum, myrrh, dragon's blood, catechu, the rosin of the parts by weight to crush jointly is fine powder, and the weight is added It is impregnated 3-7 days in the sesame oil of part, stirs 10 minutes within every 2 hours in soaking process, obtain sesame oil soak；
B the sesame oil soak) is heated to 180 DEG C -250 DEG C, is kept for 30-60 minutes in stirring, is naturally cooled to often It is filtered after temperature, removes solid insoluble therein, obtain filtered fluid；
C) filtered fluid is heated to boiling, donkey-hide gelatin, gelatin are crushed jointly as fine powder, by donkey-hide gelatin, bright while stirring Glue is put into together with beeswax in the filtered fluid of boiling, after dissolving completely, is stopped working, is naturally cooled to 30 DEG C -50 DEG C, ice is added Piece, camphor are stirred continuously to complete and melt, naturally cool to room temperature and obtain the war wound ointment for promoting muscle growth.
Sesame oil, northern China are known as sesame oil more, and sesame oil is extract from sesame, have special fragrance, therefore claim For sesame oil.The fatty acid composition model of sesame oil is defined in international food code sesame oil standard (CODEXSTAN 26-1981) It encloses.Sesame oil is generally edible per capita.Habitual constipation patient drinks some sesame oil on an empty stomach sooner or later, can relax bowel and defecation；It also is suitable for suffering from Vascular sclerosis, hypertension, coronary heart disease, hyperlipidemia, diabetes, be hard and dry be difficult to resolve, the disorders food such as ascaris intestinal obstruction person With；Sesame oil is also suitable for the person that is engaged in heavy physical labor and the people that has tobacco habit and be addicted to drink is edible.Medicine of the traditional Chinese medicine to sesame With there is higher understanding, claiming it is tonic simply, enriches blood, ease constipation, promotes the production of body fluid, promotes lactation, hair care and other effects.Suitable for body void The symptoms such as weak, graying of hair, anaemia are sallow, body fluid deficiency, dry feces, dizziness and tinnitus.
Olibanum is olive subject plant Boswellia carterii Boswellia carterii Birdw. and congener Boswellia The resin of bhaurdajiana Birdw. bark exudation.There is the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation.For the thoracic obstruction heart Bitterly, gastral cavity pain, dysmenorrhea menostasis, postpartum stasis, abdominal mass abdominal pain, rheumatic arthralgia, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Myrrh is olive subject plant Chinese violet tree Commiphora myrrha Engl. or breathes out Chinese violet tree Commiphora The dry resin of molmol Engl..With scattered stasis pain, the effect of detumescence and promoting granulation.It is usually used in chest impediment and cardialgia, gastral cavity pain, pain Through menostasis, postpartum stasis , abdominal mass and abdominal pain, rheumatic arthralgia, traumatic injury, the treatment of the illnesss such as carbuncle swells sore.
Dragon's blood, the resin for the exudation of babassu Sanguis Draxonis fruit processed are made.With promoting blood circulation analgesic therapy, stagnation resolvation stops The effect of blood, myogenic sore.For traumatic injury, trusted subordinate's stasis caused pain, traumatic hemorrhage, sore do not held back.
Catechu is the peeling branch, dry drying soft extracts of leguminous plant catechu Acacia catechu (L.f.) Willci.. With promoting blood circulation and stopping pain, the effect of hemostasia and promoting granulation, hygroscopic sore, clearing lung and eliminating phlegm.For the pain of injury caused by falling and tumbling, traumatic hemorrhage, hematemesis and epistaxis, Sore is not held back, eczema, wet sore, cough with lung heat.
Rosin, for pinaceae plant masson pine, Chinese pine or belong to several plants resin remove volatile oil after, that is retained consolidates Body resin.Transparent or translucent irregular block, differs in size, and color is by pale yellow to dark-brown.With dispelling pathogenic wind and remove dampness, arrange The effect of purulence detoxification, myogenic pain relieving.Suitable for carbuncle furuncle sore, eczema, traumatic hemorrhage, burn and scald.
Borneol also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing Deng through steam distillation and being recrystallized and obtained by composite family Blumea balsamifera cauline leaf or lauraceae plant borneol camphor tree branches and leaves.Also useful turpentine Oil is obtained through a series of chemical method techniques.It can be used for closing card coma, for red eye, swell pain, and sore throat aphtha swells for sore Bitterly, it is not held back after bursting.
Camphor, camphor are the branch, dry, leaf and root of lauraceae plant camphor tree, are refined crystalline particulate obtained.Camphor has Orifice opening, qi stagnation removing ward off the effect of foul, desinsection is antipruritic, swelling and pain relieving, cure mainly the diseases such as scabies itch, injuries from falls as well, toothache Shape.Main component is pure gum camphor (d-Camphora), is camphane class compound.
Donkey-hide gelatin is the skin of equid donkey, decocted, is concentrated manufactured solid gum, and ingredient is donkey hide, auxiliary material be yellow rice wine, Rock sugar, soya-bean oil.It originates in from general Donga area, Shandong Province.Can enrich blood enriching yin, moisturize, hemostasis.For blood deficiency chlorosis, dizziness palpitaition, the heart Tired egersis, xeropulmonary cough.
Gelatin is degraded by the collagenous portion in the connective tissues such as animal skin, bone, sarolemma, flesh evil spirit and becomes white or light Yellow, translucent, micro-strip gloss thin slice or powder；It is a kind of colorless and odorless, non-volatility, transparent hard noncrystalline material Matter dissolves in hot water, does not dissolve in cold water, but can slowly water swelling softening.Difference can be divided into gelatin depending on the application: eat bright Glue, medical gelatin, industrial gelatine.
Beeswax is apidae insect apis cerana Apis cerana Fabricius or apis mellifera Linnaeus Apis The wax of mellifera Linnaeus secretion.Honeycomb is set in water and is heated, is filtered, condensation takes wax or re-refines.It is main Ingredient has: the pure and mild carbohydrate of acids, free fatty acid, free-fat.In addition, there are also carotenoid, vitamin A, virtues Studies of The Aromatic Substances etc..The product are irregular agglomerate, not of uniform size.It is opaque or sub-translucent in yellow, fallow or yellow-white, table Face is smooth.Body is lighter, wax, section sand shape, and being pinched with hand rubbing can soften.There are honey sample fragrance, taste micro-sweet.Chinese medicine thinks, bee Wax is sweet in flavor, light, mild-natured, principal solution poison；Myogenic；Stop dysentery；Hemostasis；Analgesic therapy.Main ulcer carbuncle on the back, ulcer are to hold back；It is anxious pained；Diarrhea purulence Blood；Endless diarrhea；Vaginal bleeding with fetal movement；Spermatorrhea；Leukorrhagia.
Olibanum blood-activating and qi-promoting, detumescence and promoting granulation in above-mentioned composition have Preferred effects for traumatic injury, sore swell and ache curative；Not yet The analgesic of medicine blood-activating and qi-promoting, detumescence and promoting granulation, effectively treat wound stasis caused pain, ulcer sore pain；There is catechu hygroscopic sore, myogenic to stop blooding it Effect, has stronger effect for wet sore flowing water, unhealing ulcer, traumatic hemorrhage；Rosin has the function of eliminating dampness myogenic, and plays and kill The effect of worm is antipruritic effectively prevent trauma surface infestation；Dragon's blood hemostasia and promoting granulation sore, healing sore and relieving pain of invigorating blood circulation, in this ointment, performance stops The effect of blood and relieving pain dephlogistication and promoting nuscle growth；Borneol has clearing away heat to and alleviating pain, the effect of opening the orifice and activating blood circulation, and it is raw that clearing heat for detumescence is played in this ointment The effect of insertion tendon pain；Sesame oil can mutually fuse with said medicine as matrix and gentle skin, myogenic are put on flesh, relieve the pain detumescence The effect of；Donkey-hide gelatin gelatin had not only played the effect of hemostasia and promoting granulation, but also had the effect of tying-in, and similar phase is asked, poly- with gas phase, Quan Fangxuan medicine Special, compatibility is harmonious.
War wound ointment for promoting muscle growth of the present invention be suitable for fight (wound) hurt soft tissue lacerated wound, defect of skin, infection, out Blood, later period water outlet such as fester at the treatment of diseases.Using reasonable effective flavour of a drug, reasonable compatibility combination is carried out, with plant secretion object oil Lipid and animal glue lipid are associated with cooperation, take sesame oil as matrix progress chemical extraction, group's medicine is similar to mix, in guarantee curative effect Simultaneously, it is ensured that clinical use safety.
Specific embodiment
Embodiment 1:
War wound ointment for promoting muscle growth of the present invention, is made of the ingredient of following parts by weight
Sesame oil 50-100, olibanum 5-10, myrrh 3-12, dragon's blood 5-10, catechu 3-5, rosin 3-5, borneol 1-5, camphor 1- 3, donkey-hide gelatin 1-3, gelatin 1-3, beeswax 1-5.Specific Ingredient Amount can freely adjust in above-mentioned amount ranges.
For example, it is preferable to match are as follows: sesame oil 50, olibanum 5, myrrh 3, dragon's blood 5, catechu 3, rosin 3, borneol 1, camphor 1, donkey-hide gelatin 1, gelatin 1, beeswax 1.
Another optimum ratio is: sesame oil 100, olibanum 10, myrrh 12, dragon's blood 10, catechu 5, rosin 5, borneol 5, camphor 3, Donkey-hide gelatin 3, gelatin 3, beeswax 5.
Also can be used proportion: sesame oil 80, olibanum 8, myrrh 8, dragon's blood 8, catechu 4, rosin 4, borneol 3, camphor 2, donkey-hide gelatin 2, Gelatin 2, beeswax 3.
The preparation method of above-mentioned war wound ointment for promoting muscle growth, includes the following steps:
A) taking olibanum, myrrh, dragon's blood, catechu, the rosin of the parts by weight to crush jointly is fine powder, and the weight is added It is impregnated 3-7 days in the sesame oil of part, stirs 10 minutes within every 2 hours in soaking process, obtain sesame oil soak；
B the sesame oil soak) is heated to 180 DEG C -250 DEG C, is kept for 30-60 minutes in stirring, is naturally cooled to often It is filtered after temperature, removes solid insoluble therein, obtain filtered fluid；
C) filtered fluid is heated to boiling, donkey-hide gelatin, gelatin are crushed jointly as fine powder, by donkey-hide gelatin, bright while stirring Glue is put into together with beeswax in the filtered fluid of boiling, after dissolving completely, is stopped working, is naturally cooled to 30 DEG C -50 DEG C, ice is added Piece, camphor are stirred continuously to complete and melt, naturally cool to room temperature and obtain the war wound ointment for promoting muscle growth.
Embodiment 2:
The proportion of the war wound ointment for promoting muscle growth is the same as embodiment 1.
The hydrotropy of 2-8 parts by weight is added in the preparation method of the war wound ointment for promoting muscle growth before the heating of step C) filtered fluid Agent, the cosolvent are one of sodium benzoate, sodium salicylate, acetamide.
Efficacy analysis:
Currently on the market for hemostasia products study it is more, as zeolite, thrombin preparation, styptic sponge, hemostatic gauze with And the dry fiber albumen patch etc. that septic yanks use.It is also more for the product of myogenic, such as Chinese medicine Shengji Yuhong Gao, myogenic Scattered, rivanol Huang myogenic gauze etc..Its effect is mostly single, and the comprehensive function for playing hemostasis and pain-relieving detumescence and promoting granulation for wound produces Product are less.
The difference that war wound ointment for promoting muscle growth of the present invention plays a role by it, the method used are slightly different, can be with needle It plays a role to hemostasis, before battlefield, building site, transhipment, directly large dosage can smear wound site and hemostatic gauze is cooperated to wrap up, It only needs to apply outside in right amount when the non-emergency surface of a wound, simple covering wrapping.
Its aspect of stopping blooding makees rat tail hemostasis Experimental comparison, is compared, is led to blank control and absorbable gelatin sponge Observation bleeding stopping period, amount of bleeding are crossed, the effect discovery of evaluation war wound myogenic cream, war wound ointment for promoting muscle growth is to rat tail Hemorrhage Model There is significant anastalsis (P < 0.01).
The comparison (n=10) of 3 groups of rat tail haemostatic effects when the folder of table 1. closes 1 minute
Efficacy test of the war wound ointment for promoting muscle growth in terms of detumescence and promoting granulation uses the 0.2% rivanol Huang gauze traditional with doctor trained in Western medicine Dressing comparison, in 70 surface of a wound source investigation comparisons, using 13.0 statistics of SPSS, the percentage of enumeration data is indicated, Using X2It is examined with t, P < 0.01 is that difference is statistically significant.
2 two groups of patient's curative effects of table compare (n=35)

Claims (4)

1. war wound ointment for promoting muscle growth, it is characterised in that be made of the ingredient of following parts by weight:
Sesame oil 50-100, olibanum 5-10, myrrh 3-12, dragon's blood 5-10, catechu 3-5, rosin 3-5, borneol 1-5, camphor 1-3, Ah Glue 1-3, gelatin 1-3, beeswax 1-5.
2. war wound ointment for promoting muscle growth according to claim 1, it is characterised in that be made of the ingredient of following parts by weight: sesame oil 50, olibanum 5, myrrh 3, dragon's blood 5, catechu 3, rosin 3, borneol 1, camphor 1, donkey-hide gelatin 1, gelatin 1, beeswax 1.
3. war wound ointment for promoting muscle growth according to claim 1, it is characterised in that be made of the ingredient of following parts by weight: sesame oil 100, olibanum 10, myrrh 12, dragon's blood 10, catechu 5, rosin 5, borneol 5, camphor 3, donkey-hide gelatin 3, gelatin 3, beeswax 5.
4. the preparation method of war wound ointment for promoting muscle growth as described in claim 1-3 any one, it is characterised in that include the following steps:
A) taking olibanum, myrrh, dragon's blood, catechu, the rosin of the parts by weight to crush jointly is fine powder, and the parts by weight are added It is impregnated 3-7 days in sesame oil, stirs 10 minutes within every 2 hours in soaking process, obtain sesame oil soak；
B the sesame oil soak) is heated to 180 DEG C -250 DEG C, is kept for 30-60 minutes in stirring, after naturally cooling to room temperature Filtering, removes solid insoluble therein, obtains filtered fluid；
C) filtered fluid is heated to boiling, donkey-hide gelatin, gelatin are crushed jointly as fine powder, while stirring by donkey-hide gelatin, gelatin with Beeswax is put into together in the filtered fluid of boiling, after dissolving completely, is stopped working, is naturally cooled to 30 DEG C -50 DEG C, borneol, camphor tree is added Brain is stirred continuously to complete and melts, naturally cools to room temperature and obtain the war wound ointment for promoting muscle growth.
CN201610755237.XA 2016-08-30 2016-08-30 War wound ointment for promoting muscle growth and preparation method thereof Active CN106177313B (en)

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CN1795909A (en) * 2004-12-22 2006-07-05 北京国药苑科技有限公司 'Qili' preparationfor treating injuries from falls and production method
CN101181542A (en) * 2007-11-16 2008-05-21 李蓉 Medicament for curing traumatia
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