CN106176449A - Privates based on chitosan derivatives cleaning, antibacterial nursing mousse and preparation method - Google Patents

Privates based on chitosan derivatives cleaning, antibacterial nursing mousse and preparation method Download PDF

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Publication number
CN106176449A
CN106176449A CN201610741284.9A CN201610741284A CN106176449A CN 106176449 A CN106176449 A CN 106176449A CN 201610741284 A CN201610741284 A CN 201610741284A CN 106176449 A CN106176449 A CN 106176449A
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privates
mousse
chitosan derivatives
sodium
extract
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刘小辉
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Biological Engineering Co Ltd In Sky Is Found In Hubei
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Biological Engineering Co Ltd In Sky Is Found In Hubei
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/604Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of privates based on chitosan derivatives cleaning, antibacterial nursing mousse, it is made up of the raw material of following weight proportioning: chitosan derivatives 3%, sodium lauroyl sarcosine 8%, Sodium Alcohol Ether Sulphate 9%, sodium lauryl sulphate 1%, EDETATE SODIUM 0.05%, acetylbutyrylcellulose 1%, maleic acid Oleum Ricini 1%, APG 3%, propylene glycol 1%, cocoanut fatty acid diethanolamide 0.5%, 2, 4, 4' trichlorine 2' dihydroxy diphenyl ether 0.25%, 1, 3 dihydroxymethyls 5, 5 dimethyl hydantion 0.25%, citric acid 0.12%, essence 0.1%, menthol 0.3%, Herba Lysimachiae foenum-graeci extract 1.5%, Fructus Pruni pseudocerasi extract 1%, Flos Matricariae chamomillae extract 0.8%, surplus is deionized water.Privates based on the chitosan derivatives cleaning of the present invention, antibacterial nursing mousse and preparation method; women privates prepared by this preparation method nursing mousse is mousse foam type, have effectively cleaning privates dirt, regulation privates acid-base balance, to dispel privates abnormal flavour, suppression bacteria breed, protection privates mucosa and skin injury-free.

Description

Privates based on chitosan derivatives cleaning, antibacterial nursing mousse and preparation method
Technical field
The present invention relates to feminine hygiene technical field, be specifically related to a kind of privates based on chitosan derivatives clear Nursing mousse clean, antibacterial and preparation method.
Background technology
Along with the development of economic society, modern metropolitan cities women plays the work of irreplaceability in the development of society With, but advancing by leaps and bounds of being accompanied by cause, also it is pressed in modern female physiology while of pressure with psychological.The appearance of pressure, Directly resulting in body immunity to reduce, modern life environment is increasingly severe in addition, the development in rising trend of gynecological's class disease, women Privates conditioning liquid is seasonable and gives birth to.
Women privates conditioning liquid is different from the cleaning mixture in chemical industry washing liquid and daily life, protects specifically for women privates cleaning Reason design, has wide applicability and higher safety.At present, the washing liquid of a variety of women privates on market, they The most all there is cleaning women privates, dispel the effect such as privates abnormal flavour, preventing and treating antibacterial infection.But, these washing liquids use mostly Organic substance or Chinese medicine formula are as sterilization bacteriostat.If life-time service, antibacterial easily produces drug resistance.Traditional women is private Place's conditioning liquid dosage form is liquid, mostly uses Western medicine or important formula, only has simple cleaning, the effect of sterilization, safety Property low, the weak acidity of destructible women privates, destroy profitable strain, be easily caused your women privates redness allergy, after use, sense Feel extremely uncomfortable;Traditional women privates conditioning liquid, pungent unpleasant, offensive.
Summary of the invention
For prior art exist deficiency, novelty of the present invention provide a kind of privates based on chitosan derivatives Cleaning, antibacterial nursing mousse and preparation method thereof, cleaning, antibacterial nursing mousse prepared by this preparation method are mousse foam type, There is effectively cleaning privates dirt, light black, regulation privates acid-base balance, dispel privates abnormal flavour, suppression bacteria breed, protection privates Mucosa and skin are injury-free, moisturizing, refrigerant, antipruritic effect.
The technical scheme is that and be achieved in that:
Privates based on chitosan derivatives cleaning, antibacterial nursing mousse, be made up of the raw material of following weight proportioning: chitosan spreads out Biological 2-5%, sodium lauroyl sarcosine 5-9%, Sodium Alcohol Ether Sulphate 7-10%, sodium lauryl sulphate 0.5-1.5%, EDETATE SODIUM 0.03-0.1%, acetylbutyrylcellulose 0.5-1.5%, maleic acid Oleum Ricini 0.5-1.5%, APG 2-4%, Propylene glycol 0.5-2.5%, cocoanut fatty acid diethanolamide 0.1-1%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ether 0.2- 0.5%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.2-0.5%, citric acid 0.1-0.15%, essence 0.1-0.2%, menthol 0.2-0.4%, Herba Lysimachiae foenum-graeci extract 1-3%, Fructus Pruni pseudocerasi extract 0.5-1.5%, Flos Matricariae chamomillae extract 0.5-1%, surplus are deionized water.
Preferably, privates based on chitosan derivatives cleaning, antibacterial nursing mousse, by the raw material system of following weight proportioning Become: chitosan derivatives 3%, sodium lauroyl sarcosine 8%, Sodium Alcohol Ether Sulphate 9%, sodium lauryl sulphate 1%, EDTA Disodium 0.05%, acetylbutyrylcellulose 1%, maleic acid Oleum Ricini 1%, APG 3%, propylene glycol 1%, coco-nut oil fatty acid Diglycollic amide 0.5%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.25%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.25%, Citric acid 0.12%, essence 0.1%, menthol 0.3%, Herba Lysimachiae foenum-graeci extract 1.5%, Fructus Pruni pseudocerasi extract 1%, Flos Matricariae chamomillae extract 0.8%, Surplus is deionized water.
A kind of privates based on chitosan derivatives cleaning, the preparation method of antibacterial nursing mousse, described preparation method bag Include following steps:
(1), weigh: check various raw material as requested, standby after weighing various raw materials according to formula proportion;
(2) add in emulsifying pot main cooker after, by deionized water being heated to 90 DEG C, then main cooker will be sequentially added into Hamposyl L Sodium, Sodium Alcohol Ether Sulphate, sodium lauryl sulphate, homogenizing 10 minutes, moderate-speed mixer to each material dissolution is abundant, prepares Without granular mastic, lower the temperature after being incubated 30 minutes, add 2% loss water;
(3), mastic obtained in step (2) is cooled to 50 DEG C, then main cooker will be sequentially added into EDETATE SODIUM, acetate butyrate Cellulose, maleic acid Oleum Ricini, APG, homogenizing 2 minutes, moderate-speed mixer to each material dissolution is abundant, prepares without granule The mastic of shape, continuously stirred cooling;
(4), mastic obtained in step (3) is cooled to 38 DEG C, then main cooker will be sequentially added into propylene glycol, coconut oil fat Acid diglycollic amide, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers, chitosan derivatives, after moderate-speed mixer is uniform, sequentially add 1,3 dihydroxymethyl-5,5 dimethyl hydantion, citric acid, after moderate-speed mixer is uniform, sequentially add essence, menthol, lavandula angustifolia After extract, Fructus Pruni pseudocerasi extract, Flos Matricariae chamomillae extract, moderate-speed mixer to each material dissolution is abundant, prepares without granular mastic.
(5), inspection: sampling self-inspection, do the inspection of the PH before discharging, appearance test, under qualified rear low speed homogenizing, 100 mesh filter Discharging;The inspection of microbial bacterial sum mycete is carried out after discharging.
(6), expect that body is poured in blender, the speed of conversion 140 revs/min after the speed stirring 6-9min of 25 revs/min Degree is stirred for after 3-5min stopping stirring, adds 2% deionized water toward blender in, continues to stir, and homogenizing is after 20-30 minute, Self-inspection blowing is carried out again after standing 1-2 hour after discharging.
Further, described mixing liquid is coffee-like transparent flow liquid.
Further, the viscosity of described mixing liquid is 0pa.s~0.1pa.s.
Further, the pH value of described mixing liquid is 5.0-6.0.
Compared with prior art, the beneficial effects of the present invention is:
The invention discloses a kind of privates based on chitosan derivatives cleaning, antibacterial nursing mousse, for mousse foam type, bubble Careful, pure white, full, it is full of elasticity;Women privates nursing mousse have light black, clean, increase elasticity effect, meanwhile, energy Effectively cleaning privates dirt, light black, regulation privates acid-base balance, dispels privates abnormal flavour, suppression bacteria breed, protection privates mucosa Injury-free with skin, moisturizing, refrigerant, antipruritic effect.Women privates nursing mousse adds chitosan derivatives, belongs to natural Antibiotic substance, raw material is extensive, with low cost, is a kind of natural polysaccharide, has the molecular structure of uniqueness, is unique in natural polysaccharide A large amount of basic amine group polysaccharide existed, have antibacterial effect, add the privates nursing mousse after oligochitosan, have raising human body Immunity, prevention women privates inflammation, the effect of increase bacteriostasis and sterilization effect;Women privates nursing mousse adds lavandula angustifolia and extracts Thing, Fructus Pruni pseudocerasi extract, Flos Matricariae chamomillae extract, complement each other with other Ingredients Active factor, quickly penetrates into hair follicle disinfecting, antimicrobial, moistens Cleaning women privates, improves women privates color and luster, has the effect of cleaning and whitening, life-time service, can delay privates skin aging And increase the elasticity of privates skin, and safe and non-stimulating, without anaphylaxis, have no side effect, go for various age bracket Women uses, and recovers the women youth, promotes love life.
Detailed description of the invention
Below in conjunction with detailed description of the invention, technical scheme is clearly and completely described, it is clear that retouched The embodiment stated is only a part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, this The every other embodiment that field those of ordinary skill is obtained under not making creative work premise, broadly falls into the present invention The scope of protection.
Embodiment one:
Privates based on chitosan derivatives cleaning, antibacterial nursing mousse, be made up of the raw material of following weight proportioning: chitosan spreads out Biology 2%, sodium lauroyl sarcosine 5%, Sodium Alcohol Ether Sulphate 7%, sodium lauryl sulphate 0.5%, EDETATE SODIUM 0.03%, acetylbutyrylcellulose 0.5%, maleic acid Oleum Ricini 0.5%, APG 2%, propylene glycol 0.5%, coconut oil fat Acid diglycollic amide 0.1%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.2%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.2%, Citric acid 0.1%, essence 0.1%, menthol 0.2%, Herba Lysimachiae foenum-graeci extract 1%, Fructus Pruni pseudocerasi extract 0.5%, Flos Matricariae chamomillae extract 0.5%, Surplus is deionized water.
Further, described chitosan derivatives is chitosan, oligochitosan and carboxymethyl chitosan.
A kind of privates based on chitosan derivatives cleaning, the preparation method of antibacterial nursing mousse, described preparation method bag Include following steps:
(1), weigh: check various raw material as requested, standby after weighing various raw materials according to formula proportion;
(2) add in emulsifying pot main cooker after, by deionized water being heated to 90 DEG C, then main cooker will be sequentially added into Hamposyl L Sodium 5%, Sodium Alcohol Ether Sulphate 7%, sodium lauryl sulphate 0.5%, homogenizing 10 minutes, moderate-speed mixer is to each material dissolution Fully, prepare without granular mastic, lower the temperature after being incubated 30 minutes, add 2% loss water;
(3), mastic obtained in step (2) is cooled to 50 DEG C, then main cooker will be sequentially added into EDETATE SODIUM 0.03%, vinegar Acid cellulose butyrate 0.5%, maleic acid Oleum Ricini 0.5%, APG 2%, homogenizing 2 minutes, moderate-speed mixer is to each material dissolution Fully, prepare without granular mastic, continuously stirred cooling;
(4), mastic obtained in step (3) is cooled to 38 DEG C, then main cooker will be sequentially added into propylene glycol 0.5%, Oleum Cocois Fatty diglycollic amide 0.1%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.2%, chitosan derivatives 2%, moderate-speed mixer is equal After even, sequentially adding 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.2%, citric acid 0.1%, after moderate-speed mixer is uniform, more successively After adding essence 0.1%, menthol 0.2%, Herba Lysimachiae foenum-graeci extract 1%, Fructus Pruni pseudocerasi extract 0.5%, Flos Matricariae chamomillae extract 0.5%, middling speed is stirred Mix to each material dissolution abundant, prepare without granular mastic.
(5), inspection: sampling self-inspection, do the inspection of the PH before discharging, appearance test, under qualified rear low speed homogenizing, 100 mesh filter Discharging;The inspection of microbial bacterial sum mycete is carried out after discharging.
(6), expect that body is poured in blender, the speed of conversion 140 revs/min after the speed stirring 6min of 25 revs/min Stopping stirring after being stirred for 3min, add 2% deionized water in blender, continue stirring, homogenizing is after 20 minutes, quiet after discharging Self-inspection blowing is carried out again after putting 1 hour.
Further, described mixing liquid is coffee-like transparent flow liquid.
Further, the viscosity of described mixing liquid is 0.03pa.s.
Further, the pH value of described mixing liquid is 5.0.
Embodiment two:
Privates based on chitosan derivatives cleaning, antibacterial nursing mousse, be made up of the raw material of following weight proportioning: chitosan spreads out Biological 3%, sodium lauroyl sarcosine 8%, Sodium Alcohol Ether Sulphate 9%, sodium lauryl sulphate 1%, EDETATE SODIUM 0.05%, Acetylbutyrylcellulose 1%, maleic acid Oleum Ricini 1%, APG 3%, propylene glycol 1%, cocoanut fatty acid diethanolamide 0.5%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.25%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.25%, citric acid 0.12%, essence 0.1%, menthol 0.3%, Herba Lysimachiae foenum-graeci extract 1.5%, Fructus Pruni pseudocerasi extract 1%, Flos Matricariae chamomillae extract 0.8%, surplus are Deionized water.
Further, described chitosan derivatives is chitosan, oligochitosan and carboxymethyl chitosan.
A kind of privates based on chitosan derivatives cleaning, the preparation method of antibacterial nursing mousse, described preparation method bag Include following steps:
(1), weigh: check various raw material as requested, standby after weighing various raw materials according to formula proportion;
(2) add in emulsifying pot main cooker after, by deionized water being heated to 90 DEG C, then main cooker will be sequentially added into Hamposyl L Sodium 8%, Sodium Alcohol Ether Sulphate 9%, sodium lauryl sulphate 1%, homogenizing 10 minutes, moderate-speed mixer fills to each material dissolution Point, prepare without granular mastic, lower the temperature after being incubated 30 minutes, add 2% loss water;
(3), mastic obtained in step (2) is cooled to 50 DEG C, then main cooker will be sequentially added into EDETATE SODIUM 0.05%, vinegar Acid cellulose butyrate 1%, maleic acid Oleum Ricini 1%, APG 3%, homogenizing 2 minutes, moderate-speed mixer fills to each material dissolution Point, prepare without granular mastic, continuously stirred cooling;
(4), mastic obtained in step (3) is cooled to 38 DEG C, then main cooker will be sequentially added into propylene glycol 1%, Cortex cocois radicis oils and fats Fat acid diglycollic amide 0.5%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.25%, chitosan derivatives 3%, moderate-speed mixer is uniform After, sequentially adding 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.25%, citric acid 0.12%, after moderate-speed mixer is uniform, more successively After adding essence 0.1%, menthol 0.3%, Herba Lysimachiae foenum-graeci extract 1.5%, Fructus Pruni pseudocerasi extract 1%, Flos Matricariae chamomillae extract 0.8%, middling speed is stirred Mix to each material dissolution abundant, prepare without granular mastic.
(5), inspection: sampling self-inspection, do the inspection of the PH before discharging, appearance test, under qualified rear low speed homogenizing, 100 mesh filter Discharging;The inspection of microbial bacterial sum mycete is carried out after discharging.
(6), expect that body is poured in blender, the speed of conversion 140 revs/min after the speed stirring 7.5min of 25 revs/min Degree stops stirring after being stirred for 4min, adds 2% deionized water in blender, continues stirring, and homogenizing is after 25 minutes, after discharging Self-inspection blowing is carried out again after standing 1.5 hours.
Further, described mixing liquid is coffee-like transparent flow liquid.
Further, the viscosity of described mixing liquid is 0.07pa.s.
Further, the pH value of described mixing liquid is 5.5.
Embodiment three:
Privates based on chitosan derivatives cleaning, antibacterial nursing mousse, be made up of the raw material of following weight proportioning: chitosan spreads out Biology 5%, sodium lauroyl sarcosine 9%, Sodium Alcohol Ether Sulphate 10%, sodium lauryl sulphate 1.5%, EDETATE SODIUM 0.1%, acetylbutyrylcellulose 1.5%, maleic acid Oleum Ricini 1.5%, APG 4%, propylene glycol 2.5%, coco-nut oil fatty acid Diglycollic amide 1%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.5%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.5%, Fructus Citri Limoniae Acid 0.15%, essence 0.2%, menthol 0.4%, Herba Lysimachiae foenum-graeci extract 3%, Fructus Pruni pseudocerasi extract 1.5%, Flos Matricariae chamomillae extract 1%, surplus are Deionized water.
A kind of privates based on chitosan derivatives cleaning, the preparation method of antibacterial nursing mousse, described preparation method bag Include following steps:
(1), weigh: check various raw material as requested, standby after weighing various raw materials according to formula proportion;
(2) add in emulsifying pot main cooker after, by deionized water being heated to 90 DEG C, then main cooker will be sequentially added into Hamposyl L Sodium 9%, Sodium Alcohol Ether Sulphate 10%, sodium lauryl sulphate 1.5%, homogenizing 10 minutes, moderate-speed mixer is to each material dissolution Fully, prepare without granular mastic, lower the temperature after being incubated 30 minutes, add 2% loss water;
(3), mastic obtained in step (2) is cooled to 50 DEG C, then main cooker will be sequentially added into EDETATE SODIUM 0.1%, acetic acid Cellulose butyrate 1.5%, maleic acid Oleum Ricini 1.5%, APG 4%, homogenizing 2 minutes, moderate-speed mixer fills to each material dissolution Point, prepare without granular mastic, continuously stirred cooling;
(4), mastic obtained in step (3) is cooled to 38 DEG C, then main cooker will be sequentially added into propylene glycol 2.5%, Oleum Cocois Fatty diglycollic amide 1%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers 0.5%, chitosan derivatives 5%, moderate-speed mixer is uniform After, sequentially adding 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.5%, citric acid 0.15%, after moderate-speed mixer is uniform, more successively After adding essence 0.2%, menthol 0.4%, Herba Lysimachiae foenum-graeci extract 3%, Fructus Pruni pseudocerasi extract 1.5%, Flos Matricariae chamomillae extract 1%, moderate-speed mixer Abundant to each material dissolution, prepare without granular mastic.
(5), inspection: sampling self-inspection, do the inspection of the PH before discharging, appearance test, under qualified rear low speed homogenizing, 100 mesh filter Discharging;The inspection of microbial bacterial sum mycete is carried out after discharging.
(6), expect that body is poured in blender, the speed of conversion 140 revs/min after the speed stirring 9min of 25 revs/min Stopping stirring after being stirred for 5min, add 2% deionized water in blender, continue stirring, homogenizing is after 30 minutes, quiet after discharging Self-inspection blowing is carried out again after putting 1-2 hour.
Further, described mixing liquid is coffee-like transparent flow liquid.
Further, the viscosity of described mixing liquid is 0.1pa.s.
Further, the pH value of described mixing liquid is 6.0.
Certainly, described above is not limitation of the present invention, and the present invention is also not limited to the example above, the art Those of ordinary skill, in the essential scope of the present invention, the change made, retrofit, add or replace, all should belong to the present invention Protection domain.

Claims (7)

1. privates based on chitosan derivatives cleaning, antibacterial nursing mousse, it is characterised in that by the raw material of following weight proportioning Make: chitosan derivatives 2-5%, sodium lauroyl sarcosine 5-9%, Sodium Alcohol Ether Sulphate 7-10%, dodecyl Sodium sulfate 0.5-1.5%, EDETATE SODIUM 0.03-0.1%, acetylbutyrylcellulose 0.5-1.5%, maleic acid Oleum Ricini 0.5- 1.5%, APG 2-4%, propylene glycol 0.5-2.5%, cocoanut fatty acid diethanolamide 0.1-1%, 2,4,4'-tri- Chloro-2'-dihydroxy diphenyl ether 0.2-0.5%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.2-0.5%, citric acid 0.1- 0.15%, essence 0.1-0.2%, menthol 0.2-0.4%, Herba Lysimachiae foenum-graeci extract 1-3%, Fructus Pruni pseudocerasi extract 0.5-1.5%, mother Chrysanthemum extract 0.5-1%, surplus are deionized water.
Privates based on chitosan derivatives the most according to claim 1 cleaning, antibacterial nursing mousse, it is characterised in that It is made up of the raw material of following weight proportioning: chitosan derivatives 3%, sodium lauroyl sarcosine 8%, Sodium Alcohol Ether Sulphate 9%, sodium lauryl sulphate 1%, EDETATE SODIUM 0.05%, acetylbutyrylcellulose 1%, maleic acid Oleum Ricini 1%, alkyl are many Glucosides 3%, propylene glycol 1%, cocoanut fatty acid diethanolamide 0.5%, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ether 0.25%, 1,3 dihydroxymethyl-5,5 dimethyl hydantion 0.25%, citric acid 0.12%, essence 0.1%, menthol 0.3%, smoke Clothing grass extract 1.5%, Fructus Pruni pseudocerasi extract 1%, Flos Matricariae chamomillae extract 0.8%, surplus are deionized water.
Privates based on chitosan derivatives the most according to claim 1 cleaning, antibacterial nursing mousse, it is characterised in that Described chitosan derivatives is chitosan, oligochitosan and carboxymethyl chitosan.
4. clean according to the privates based on chitosan derivatives described in claim any one of claim 1-3, antibacterial protect The preparation method of reason mousse, it is characterised in that described preparation method comprises the following steps:
(1), weigh: check various raw material as requested, standby after weighing various raw materials according to formula proportion;
(2) add in emulsifying pot main cooker after, by deionized water being heated to 90 DEG C, then main cooker will be sequentially added into Hamposyl L Sodium, Sodium Alcohol Ether Sulphate, sodium lauryl sulphate, homogenizing 10 minutes, moderate-speed mixer to each material dissolution is abundant, prepares Without granular mastic, lower the temperature after being incubated 30 minutes, add 2% loss water;
(3), mastic obtained in step (2) is cooled to 50 DEG C, then main cooker will be sequentially added into EDETATE SODIUM, acetate butyrate Cellulose, maleic acid Oleum Ricini, APG, homogenizing 2 minutes, moderate-speed mixer to each material dissolution is abundant, prepares without granule The mastic of shape, continuously stirred cooling;
(4), mastic obtained in step (3) is cooled to 38 DEG C, then main cooker will be sequentially added into propylene glycol, coconut oil fat Acid diglycollic amide, 2,4,4'-tri-chloro-2'-dihydroxy diphenyl ethers, chitosan derivatives, after moderate-speed mixer is uniform, sequentially add 1,3 dihydroxymethyl-5,5 dimethyl hydantion, citric acid, after moderate-speed mixer is uniform, sequentially add essence, menthol, lavandula angustifolia After extract, Fructus Pruni pseudocerasi extract, Flos Matricariae chamomillae extract, moderate-speed mixer to each material dissolution is abundant, prepares without granular mastic.
(5), inspection: sampling self-inspection, do the inspection of the PH before discharging, appearance test, under qualified rear low speed homogenizing, 100 mesh filter out Material;The inspection of microbial bacterial sum mycete is carried out after discharging.
(6), expecting that body is poured in blender, after the speed stirring 6-9min of 25 revs/min, the speed of conversion 140 revs/min is stirred again Stopping stirring after mixing 3-5min, add 2% deionized water in blender, continue stirring, homogenizing is after 20-30 minute, after discharging Self-inspection blowing is carried out again after standing 1-2 hour.
Privates based on chitosan derivatives the most according to claim 4 cleaning, the preparation method of antibacterial nursing mousse, its Being characterised by, described mixing liquid is coffee-like transparent flow liquid.
Privates based on chitosan derivatives the most according to claim 4 cleaning, the preparation method of antibacterial nursing mousse, its Being characterised by, the viscosity of described mixing liquid is 0pa.s~0.1pa.s.
Privates based on chitosan derivatives the most according to claim 4 cleaning, the preparation method of antibacterial nursing mousse, its Being characterised by, the pH value of described mixing liquid is 5.0-6.0.
CN201610741284.9A 2016-08-26 2016-08-26 Privates based on chitosan derivatives cleaning, antibacterial nursing mousse and preparation method Pending CN106176449A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403520A (en) * 2018-05-07 2018-08-17 青岛高新区尚达医药研究所 A kind of chitosan Mrs Chinese herbal medicine conditioning liquid and its application
WO2020054937A1 (en) * 2018-09-14 2020-03-19 주식회사 엔도비전 Feminine cleanser composition using vegetable chitosan, preparation method therefor, and feminine cleanser comprising same
CN115670954A (en) * 2022-10-24 2023-02-03 青岛健康海洋生物制药有限公司 No-clean private part cleaning mousse and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791319A (en) * 2010-04-07 2010-08-04 北京欧凯纳斯科技有限公司 Female pudendum nursing product
CN105055183A (en) * 2015-08-03 2015-11-18 李彦 Female vagina cleaning care liquid and method for preparing same
CN105327339A (en) * 2014-08-15 2016-02-17 人福医药集团医疗用品有限公司 Chitosan gel particle lotion and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101791319A (en) * 2010-04-07 2010-08-04 北京欧凯纳斯科技有限公司 Female pudendum nursing product
CN105327339A (en) * 2014-08-15 2016-02-17 人福医药集团医疗用品有限公司 Chitosan gel particle lotion and preparation method thereof
CN105055183A (en) * 2015-08-03 2015-11-18 李彦 Female vagina cleaning care liquid and method for preparing same

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403520A (en) * 2018-05-07 2018-08-17 青岛高新区尚达医药研究所 A kind of chitosan Mrs Chinese herbal medicine conditioning liquid and its application
WO2020054937A1 (en) * 2018-09-14 2020-03-19 주식회사 엔도비전 Feminine cleanser composition using vegetable chitosan, preparation method therefor, and feminine cleanser comprising same
CN115670954A (en) * 2022-10-24 2023-02-03 青岛健康海洋生物制药有限公司 No-clean private part cleaning mousse and preparation method thereof
CN115670954B (en) * 2022-10-24 2024-02-13 青岛健康海洋生物制药有限公司 Wash-free private cleaning mousse and preparation method thereof

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Application publication date: 20161207