CN106176338B - A kind of anti-aging cosmetics composition and preparation method thereof - Google Patents
A kind of anti-aging cosmetics composition and preparation method thereof Download PDFInfo
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- CN106176338B CN106176338B CN201610538995.6A CN201610538995A CN106176338B CN 106176338 B CN106176338 B CN 106176338B CN 201610538995 A CN201610538995 A CN 201610538995A CN 106176338 B CN106176338 B CN 106176338B
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- safflower
- semen coicis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The present invention relates to a kind of anti-aging cosmetics compositions, belong to cosmetic field, and active constituent is composed of Rubus corchorifolius extract, safflower extract, black bearberry leaf extract, Semen Coicis extract and Herba Schizonepetae extract, and test result shows that its anti-aging effects is excellent.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of anti-aging cosmetics composition and preparation method thereof.
Background technique
Beautiful and youth is the pursuit of women invariability, thus has the skin care item of senile-resistant efficacy always by pushing away
It is high, however, most of product in the market is all made an overstatement, use that actual effect is general, and the present invention is directed to study one
Kind anti-aging effects are significantly containing the skin care item of natural component.
Rubus corchorifolius (Rubus corchorifolius L.f.) also known as raspberry, mountain throw son, milk bubble, spread seedling bubble, steep March,
It steeps April, dragon-boat bubble, barley bubble, pierces cucurbit, steamed bun spinach, high foot wave at bubble youngster thorn, has the supporing yang improving eyesight of arresting seminal emission kidney-nourishing, sobers up only
Yearningly, the effect of resolving sputum is detoxified, cures mainly the diseases such as kidney deficiency, spermatorrhea, drunk, erysipelas.The study found that stilbene constituents, flower that Rubus corchorifolius contains
Green glucoside, vitamin and SOD (superoxide dismutase) all have significant antioxidation, also containing vitamin B1, dimension life
Plain B2, vitamin E, carotene etc., therefore nutritive value with higher and medical care effect.It has been verified from Rubus corchorifolius
Ingredient see that flavone compound has hypoglycemic, reducing blood lipid, anti-arrhythmia cordis, anti-oxidant high efficiency and hypotoxicity, anti-aging
Equal physiological activity.Scopolactone has the function of certain analgesia, anti-inflammatory, eliminating the phlegm and relievings asthma.Tea polyphenols have decompression, drop blood
The effect of rouge, anti-mutation, prevention and cure of cardiovascular disease, antibacterial anti-inflammatory, also has and eliminates free radical, cancer-resisting, anti-lipid peroxy
The effects of change and anti-aging.SOD radiation protection, anti-aging, prevent in terms of have unique function, be added to drug, makeup
Anti-inflammatory, anti-aging effects can be played in product.
Safflower (Carthamus tinctorius L.), alias: red blue flower, thorn safflower, composite family, safflower plant are dry
Tubular flower, orange red, floral tube is narrow thin, and apex 5 is split, sliver narrow line shape, and anther yellow is unified into pipe, is higher by except sliver,
There is column cap exposing in center.Have special fragrance, mildly bitter flavor.It is long with flower piece, color is scarlet, the soft person of matter is preferred.Safflower has anti-oxidant
Effect, while there is antifatigue effect, studies have shown that carthamin yellow 1100mg/kg mouse and control group (use normal salt
Water) compare, swimming time is obviously prolonged, and rate elongation is up to 117.0%, P < 0.01.
Black bearberry also known as bear grape, the bear certain kind of berries (Bearberry) are a kind of plants that Ericaceae black bearberry belongs to.Black bearberry can be cooked
For medicinal plant.Uva ursi is the leaf of black bearberry, and containing Arbutin, the effect of black bearberry is known as antibacterial, is a kind of mild benefit
Agent is urinated, can be used to treat the disease of urinary system.Arbutin can also reduce the formation of dermal melanin, the function with whitening
Effect, and be used in cosmetics.
Semen Coicis (Coix chinensis Tod.), is called: semen coicis, the seed of jog's tears, maize, are gramineae
Kernel.Its is cool in nature, sweet in flavor, light, enters spleen, lung, kidney channel, has effects that Li Shui, invigorating the spleen, eliminating impediment, clearing away heat and eliminating pus.Semen Coicis is rich in egg
8 kinds of amino acid necessary to white matter, carbohydrate and human body has very strong white-skinned face function, at the same can make skin become it is smooth,
It is fine and smooth.Minerals contained by Semen Coicis have the function of releiving, it is calm shine after skin, vitamin B group with anti-inflammatory, oil-control, guarantor
The effect of wet water lock, Coixol have the function of preventing it is tanned, improve dry skin situation, adlay rouge, which has, promotes new old generation
It thanks, the effect for allowing rough thick wrong skin to smooth out.
Schizonepeta (Nepeta cataria L.), alias: fragrant chaste tree shepherd's purse, line shepherd's purse, tetragonous bar wormwood artemisia, false Soviet Union, are Labiatae, schizonepeta
Belong to perennial plant, contain volatile oil 1.8%, principal component is D-menthone, racemization book lotus ketone, a small amount of dextrorotation lemon in oil
Alkene, Herba Schizonepetae extract have inhibiting effect to clostridiopetidase A.
The anti-aging cosmetics that the present invention is researched and developed exactly are composed of Rubus corchorifolius, safflower, uva ursi, Semen Coicis and schizonepeta
, it is proved by effect test, anti-aging effects are excellent.
Summary of the invention
The purpose of the present invention is overcoming the deficiencies of existing technologies, a kind of effective anti-aging cosmetics combination is provided
Object, formula composition are as follows:
A phase: 15-20 parts of Rubus corchorifolius extract, 4-6 parts of Semen Coicis extract, 6-10 parts of safflower extract, black bearberry leaf extract
12-15 parts, 2-5 parts of Herba Schizonepetae extract, 10-15 parts of hyaluronic acid, 3-8 parts of cetanol ethylhexoate, C16-18 alcohol 12-15
Part, 3-12 parts of glycerol, 150-200 parts of deionized water；
B phase: 6-10 parts of avocado oil, 30-50 parts of dimethicone, 6-10 parts of Magnesium Ascorbyl Phosphate, sher butter 15-18
Part, 12-15 parts of carbomer, 8-10 parts of evening primrose oil, 1-5 parts of Salvia japonica essential oil, 15-20 parts of lanolin, octyldodecanol 12-
14 parts；
Preservative, appropriate essence.
Preferably, formula forms are as follows:
A phase: 18 parts of Rubus corchorifolius extract, 5 parts of Semen Coicis extract, 10 parts of safflower extract, 15 parts of black bearberry leaf extract, schizonepeta
2 parts of extract, 12 parts of hyaluronic acid, 6 parts of cetanol ethylhexoate, 12 parts of C16-18 alcohol, 10 parts of glycerol, deionized water 200
Part；
B phase: 8 parts of avocado oil, 40 parts of dimethicone, 8 parts of Magnesium Ascorbyl Phosphate, 16 parts of sher butter, carbomer 12
Part, 10 parts of evening primrose oil, 4 parts of Salvia japonica essential oil, 18 parts of lanolin, 12 parts of octyldodecanol.
The Rubus corchorifolius extract, safflower extract, black bearberry leaf extract, Semen Coicis extract and Herba Schizonepetae extract can pass through
Water commonly used in the art mentions or the preparation of the method for alcohol extracting.
For example, the Rubus corchorifolius extract, safflower extract and black bearberry leaf extract the preparation method comprises the following steps: by Rubus corchorifolius, safflower
Or uva ursi presses solid-liquid ratio 1:(10-15) distilled water is added in 80 DEG C of extraction 1-2h, in triplicate, filtering, merging filtrate depressurizes
Concentration, with 90% ethyl alcohol alcohol precipitation 3 times of 6-8 times of volume, filtering, will precipitating it is dry to get；
The Semen Coicis extract and Herba Schizonepetae extract the preparation method comprises the following steps: petroleum ether degreasing is added in Semen Coicis or schizonepeta after
Solid-liquid ratio 1:(10-15 is pressed with 60% ethyl alcohol) in 50 DEG C of extraction 0.5-1h, it repeats to extract three times, merging filtrate is rotated in 90 DEG C
Evaporate to obtain thick paste, dry, pulverize to get.
Invention also provides the preparation method of above-mentioned anti-aging cosmetics composition, operating procedures are as follows:
(1) A phase each component heating stirring is uniform；
(2) B phase each component heating stirring is uniform；
(3) A phase and B are mixed uniformly, preservative and essence are added, stirs evenly, it is cooling to get.
The heating temperature of the A phase and B phase is preferably 80-85 DEG C.
The active constituent of anti-aging cosmetics composition of the invention is mentioned by Rubus corchorifolius extract, safflower extract, uva ursi
Object, Semen Coicis extract and Herba Schizonepetae extract is taken to be composed, test result shows that its anti-aging effects is excellent.
Specific embodiment
The preparation of plant extracts
Distilled water is added in 80 DEG C of extraction 1.5h, in triplicate, mistake by solid-liquid ratio 1:12 in Rubus corchorifolius, safflower or uva ursi
Filter, merging filtrate are concentrated under reduced pressure, and with 90% ethyl alcohol alcohol precipitation 3 times of 7 times of volumes, filtering will precipitate drying, obtain Rubus corchorifolius respectively and mention
Take object, safflower extract and black bearberry leaf extract；It is added in Semen Coicis or schizonepeta after petroleum ether degreasing and presses feed liquid with 60% ethyl alcohol
It than 1:15 in 50 DEG C of extraction 1h, repeats to extract three times, merging filtrate obtains thick paste in 90 DEG C of rotary evaporations, dry, pulverize, respectively
Obtain Semen Coicis extract and Herba Schizonepetae extract.
Embodiment 1
Raw material is taken by following composition:
A phase: 15 parts of Rubus corchorifolius extract, 4 parts of Semen Coicis extract, 7 parts of safflower extract, 12 parts of black bearberry leaf extract, schizonepeta
2 parts of extract, 12 parts of hyaluronic acid, 4 parts of cetanol ethylhexoate, 12 parts of C16-18 alcohol, 5 parts of glycerol, deionized water 150
Part；
B phase: 6 parts of avocado oil, 30 parts of dimethicone, 6 parts of Magnesium Ascorbyl Phosphate, 15 parts of sher butter, carbomer 14
Part, 8 parts of evening primrose oil, 2 parts of Salvia japonica essential oil, 20 parts of lanolin, 12 parts of octyldodecanol；
The each component of A phase and B phase is uniform respectively at 80 DEG C of heating stirrings, then the two is uniformly mixed, anti-corrosion is added
Agent and essence, stir evenly, it is cooling to get.
Embodiment 2
Raw material is taken by following composition:
A phase: 18 parts of Rubus corchorifolius extract, 5 parts of Semen Coicis extract, 8 parts of safflower extract, 13 parts of black bearberry leaf extract, schizonepeta
4 parts of extract, 13 parts of hyaluronic acid, 6 parts of cetanol ethylhexoate, 14 parts of C16-18 alcohol, 8 parts of glycerol, deionized water 180
Part；
B phase: 8 parts of avocado oil, 40 parts of dimethicone, 8 parts of Magnesium Ascorbyl Phosphate, 16 parts of sher butter, carbomer 14
Part, 9 parts of evening primrose oil, 3 parts of Salvia japonica essential oil, 18 parts of lanolin, 13 parts of octyldodecanol；
The each component of A phase and B phase is uniform respectively at 80 DEG C of heating stirrings, then the two is uniformly mixed, anti-corrosion is added
Agent and essence, stir evenly, it is cooling to get.
Embodiment 3
Raw material is taken by following composition:
A phase: 20 parts of Rubus corchorifolius extract, 6 parts of Semen Coicis extract, 10 parts of safflower extract, 15 parts of black bearberry leaf extract, schizonepeta
5 parts of extract, 15 parts of hyaluronic acid, 8 parts of cetanol ethylhexoate, 15 parts of C16-18 alcohol, 12 parts of glycerol, deionized water 200
Part；
B phase: 10 parts of avocado oil, 50 parts of dimethicone, 10 parts of Magnesium Ascorbyl Phosphate, 18 parts of sher butter, carbomer 15
Part, 10 parts of evening primrose oil, 5 parts of Salvia japonica essential oil, 20 parts of lanolin, 14 parts of octyldodecanol；
The each component of A phase and B phase is uniform respectively at 85 DEG C of heating stirrings, then the two is uniformly mixed, anti-corrosion is added
Agent and essence, stir evenly, it is cooling to get.
Embodiment 4:
The Antisenility Experiment of fructus lycii anti-aging extract:
Aged Mice 40 are taken, 4 groups is randomly divided into, every group 10, gavages the anti-aging cosmetics group of embodiment 1-3 respectively
Five Plant Extracts mixture 100mg/kg in object are closed, physiological saline 0.5mL/ only, under equal conditions, feeds continuous 30
It, eye socket blood sampling in 2 hours after last time is administered measures SOD and LPO content, takes tail eyelash measurement HO-Pro to contain after putting to death mouse
Amount.The results are shown in Table 1:
Influence of the 1 anti-aging cosmetics composition object of table to Aged Mice SOD, LPO, HO-PRO
| SOD(u/ghb) | LPO(mol/ml) | HO-Pro(mg/5mg) | |
| Physiological saline group | 1311 | 8.43 | 3.27 |
| Embodiment 1 | 2612 | 4.11 | 5.21 |
| Embodiment 2 | 2633 | 4.01 | 5.00 |
| Embodiment 3 | 2642 | 4.18 | 5.02 |
Meanwhile mouse 40 are taken, 4 groups are randomly divided into, every group 10, gavages the anti-aging cosmetics of embodiment 1-3 respectively
Five Plant Extracts mixture 100mg/kg in composition, physiological saline 0.5mL/ only, under equal conditions, feed continuous 30
It, carries out endurance measurement respectively, according to 15% weight bearing of mouse weight, in depth of water 60cm, 22 DEG C of water temperature of water went swimming, with mouse
The no longer floating that sinks under water is index, measures their swimming time.The results are shown in Table 2:
Influence of the 2 anti-aging cosmetics composition of table to mouse swimming time
| Physiological saline group | Embodiment 1 | Embodiment 2 | Embodiment 3 | |
| Swimming time (s) | 46.8 | 88.2 | 91.3 | 99.1 |
The results show that anti-aging cosmetics composition of the invention can significantly reduce LPO level in Aged Mice serum,
SOD activity in Aged Mice red blood cell is improved, while being able to extend mouse and improving endurance, extends mouse swimming time, thus can
Damage caused by interior free yl is effectively removed, to reduce the generation and anti-aging of disease.
Claims (4)
1. a kind of anti-aging cosmetics composition, which is characterized in that its formula composition are as follows:
A phase: 15-20 parts of Rubus corchorifolius extract, 4-6 parts of Semen Coicis extract, 6-10 parts of safflower extract, black bearberry leaf extract 12-15
Part, 2-5 parts of Herba Schizonepetae extract, 10-15 parts of hyaluronic acid, 3-8 parts of cetanol ethylhexoate, 12-15 parts of C16-18 alcohol, glycerol
3-12 parts, 150-200 parts of deionized water；
B phase: 6-10 parts of avocado oil, 30-50 parts of dimethicone, 6-10 parts of Magnesium Ascorbyl Phosphate, 15-18 parts of sher butter, card
12-15 parts of wave nurse, 8-10 parts of evening primrose oil, 1-5 parts of Salvia japonica essential oil, 15-20 parts of lanolin, 12-14 parts of octyldodecanol；
Preservative, appropriate essence；
The Rubus corchorifolius extract, safflower extract and black bearberry leaf extract the preparation method comprises the following steps: Rubus corchorifolius, safflower or uva ursi are pressed
Solid-liquid ratio 1:(10-15) distilled water is added in 80 DEG C of extraction 1-2h, in triplicate, filtering, merging filtrate is concentrated under reduced pressure, uses 6-8
90% ethyl alcohol alcohol precipitation 3 times of times volume, filtering, will precipitating it is dry to get；
The Semen Coicis extract and Herba Schizonepetae extract the preparation method comprises the following steps: petroleum ether degreasing is added in Semen Coicis or schizonepeta after use
60% ethyl alcohol presses solid-liquid ratio 1:(10-15) in 50 DEG C of extraction 0.5-1h, it repeats to extract three times, merging filtrate is steamed in 90 DEG C of rotations
Send out to obtain thick paste, dry, pulverize to get.
2. anti-aging cosmetics composition according to claim 1, which is characterized in that its formula composition is preferred
Are as follows:
A phase: 18 parts of Rubus corchorifolius extract, 5 parts of Semen Coicis extract, 10 parts of safflower extract, 15 parts of black bearberry leaf extract, schizonepeta is extracted
2 parts of object, 12 parts of hyaluronic acid, 6 parts of cetanol ethylhexoate, 12 parts of C16-18 alcohol, 10 parts of glycerol, 200 parts of deionized water；
B phase: 8 parts of avocado oil, 40 parts of dimethicone, 8 parts of Magnesium Ascorbyl Phosphate, 16 parts of sher butter, 12 parts of carbomer, the moon
See careless 10 parts, 4 parts of Salvia japonica essential oil, 18 parts of lanolin, 12 parts of octyldodecanol of oil.
3. according to claim 1 or the preparation method of 2 described in any item anti-aging cosmetics compositions, which is characterized in that its
Operating procedure are as follows:
(1) A phase each component heating stirring is uniform；
(2) B phase each component heating stirring is uniform；
(3) A phase and B are mixed uniformly, preservative and essence are added, stirs evenly, it is cooling to get.
4. preparation method according to claim 3, which is characterized in that the heating temperature of the A phase and B phase is preferably 80-
85℃。
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| CN201610538995.6A CN106176338B (en) | 2016-07-09 | 2016-07-09 | A kind of anti-aging cosmetics composition and preparation method thereof |
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| CN106176338B true CN106176338B (en) | 2019-01-29 |
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| CN106691920A (en) * | 2016-12-08 | 2017-05-24 | 郭保国 | Raspberry root mask rich in SOD |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077864A (en) * | 2007-07-04 | 2007-11-28 | 北京绿色金可生物技术股份有限公司 | Vaccinnium vitis-idaea extract, preparation method and application thereof |
| CN102113992A (en) * | 2011-02-25 | 2011-07-06 | 广州市天吻娇颜化妆品有限公司 | Externally applied composite with breast enhancement function and preparation method thereof |
| CN103393568A (en) * | 2013-07-28 | 2013-11-20 | 娇时化妆品（杭州）有限公司 | Whitening and freckle-removing cream |
| CN103830152A (en) * | 2014-03-14 | 2014-06-04 | 集安五味堂生物科技有限公司 | Cosmetic composition and essence with skin whitening function |
| CN105395405A (en) * | 2015-11-30 | 2016-03-16 | 梁宏盛 | Whitening and freckle removing cream and preparation method thereof |
-
2016
- 2016-07-09 CN CN201610538995.6A patent/CN106176338B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077864A (en) * | 2007-07-04 | 2007-11-28 | 北京绿色金可生物技术股份有限公司 | Vaccinnium vitis-idaea extract, preparation method and application thereof |
| CN102113992A (en) * | 2011-02-25 | 2011-07-06 | 广州市天吻娇颜化妆品有限公司 | Externally applied composite with breast enhancement function and preparation method thereof |
| CN103393568A (en) * | 2013-07-28 | 2013-11-20 | 娇时化妆品（杭州）有限公司 | Whitening and freckle-removing cream |
| CN103830152A (en) * | 2014-03-14 | 2014-06-04 | 集安五味堂生物科技有限公司 | Cosmetic composition and essence with skin whitening function |
| CN105395405A (en) * | 2015-11-30 | 2016-03-16 | 梁宏盛 | Whitening and freckle removing cream and preparation method thereof |
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Effective date of registration: 20190411 Address after: 510920 Hengjiang Road 339-32, Conghua Suburb Street, Guangzhou, Guangdong Province Patentee after: Guangzhou Lancs Cosmetics Co. Ltd. Address before: No. 308, Ningxia Road, Southern District, Shandong, Qingdao, Shandong Patentee before: Qingdao University |